Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(-)-Epicatechin[1] Epicatechin---[2] 86, 113 💬
2(18F)FPGLU----[1] 86 💬
3(Pyr1)apelin-13[1] Apelin---[1] 86 💬
4(S)-2-(4,6-dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropanoic acid----[1] 86 💬
5(S)-3-((3-(1-((6-(3,4-DIMETHOXYPHENYL)PRYAZIN-2- YL)AMINO)ETHYL)PHENYL)CARBAMOYL)-5-METHYLPRIDIN-1-IUM----[1] 86 💬
6(S)-3-((3-(1-((6-(3,4-DIMETHOXYPHENYL)PRYAZIN-2-YL)AMINO)ETHYL)PHENYL)CARBAMOYL)-5-METHYLPRIDIN-1-IUM----[1] 86 💬
7**Comment**- IMP inhalation solution identical to ventavis inhalation solution, but IMP is in a different volume presentation. Please see covering letter.----[1] 86 💬
810-nitro-9(E)-octadec-9-enoic acid[1] CXA-10---[1] 86 💬
911C-acetate[1] Acetate---[2] 86, 88 💬
10120 mg sodium nitrite inhalation solution[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[1] 86 💬
11129Xe Hyperpolarized----[1] 86 💬
1215 mg sodium nitrite inhalation solution[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[1] 86 💬
13150mg CXA-10[1] CXA-10---[1] 86 💬
14171----[1] 86 💬
152-(4-[5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy)-N-(methylsulfonyl)actamide----[1] 86 💬
162-HOBA----[2] 46, 86 💬
172-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl) acetamide[1] Acetamide---[1] 86 💬
1820 mg sildenafil citrate by mouth[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
1920 mg/ml Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
2025% MTD sodium nitrite inhalation solution[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[1] 86 💬
212D and 3D trans-thoracic echocardiography----[2] 86, 88 💬
22400 mg BIA 5-1058[1] BIA---[1] 86 💬
2345 mg sodium nitrite inhalation solution[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[1] 86 💬
244AU76----[1] 86 💬
2566215-101----[1] 86 💬
2675mg CXA-10[1] CXA-10---[1] 86 💬
2790 mg sodium nitrite inhalation solution[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[1] 86 💬
28: 2-{4-[(5,6-difenilpirazin-2-yl)(isopropil)amino]butoxi}-N-----[1] 86 💬
29[11C]-GSK2256098 500 MBq[1] GSK2256098---[1] 86 💬
30[18F] FES----[1] 86 💬
31[18F]FAPI-74----[1] 86 💬
32[18F]Fluoro-2-deoxy-2-D-glucose[1] D-glucose[1] Glucose 💬 --[2] 86, 88 💬
33[ACE-011]----[1] 86 💬
34[ACT-064992]----[1] 86 💬
35[APD811]----[1] 86 💬
36[BIA 5-1058][1] BIA---[1] 86 💬
37[BIA-5-1058][1] BIA---[1] 86 💬
38[CJNJ-68150420-ZZZ-G001 (ACT- 064992D)]----[1] 86 💬
39[G04BE08]----[1] 86 💬
40[INS1009]----[1] 86 💬
41[JNJ-67896049 (ACT-293987)]----[1] 86 💬
42[JNJ-67896062 / ACT-064992]----[2] 86, 88 💬
43[JNJ-67896062/ ACT-064992]----[2] 86, 88 💬
44[MK-4836]----[1] 86 💬
45[MK-5475]----[1] 86 💬
46[RVT-1201]----[1] 86 💬
47Access program - sildenafil citrate, Viagra, Revatio[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
48ACE-011----[1] 86 💬
49ACE-011 / ??-7962----[1] 86 💬
50ACE-011 / MK - 7962----[1] 86 💬
51ACE-011 / MK-7962----[1] 86 💬
52ACE-011/ MK-7962----[1] 86 💬
53Acetamide[1] Acetamide---[3] 65, 86, 154 💬
54Acetaminophen[1] Acetaminophen[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
55Acetate[1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
56ACT - 064992----[1] 86 💬
57ACT-050089----[1] 86 💬
58ACT-050089 (Ro 61-0612)----[1] 86 💬
59ACT-064992----[5] 51, 85, 86, 88, 210 💬
60ACT-064992 / JNJ-67896062----[1] 86 💬
61ACT-064992/ JNJ-67896062----[1] 86 💬
62ACT-064992D----[1] 86 💬
63ACT-178418----[1] 86 💬
64ACT-293987----[3] 51, 86, 88 💬
65ACT-293987 (NS-304)----[1] 86 💬
66ACT-385781A----[1] 86 💬
67ACT-385781A (Actelion Epoprostenol)[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
68ActRIIA-IgG1Fc----[1] 86 💬
69Adcirca----[1] 86 💬
70ADCIRCA 20 mg film-coated tablets----[1] 86 💬
71Adcirca®----[1] 86 💬
72Adempas----[5] 51, 86, 88, 225, 299 💬
73Adempas (Riociguat, BAY63-2521)[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
74ADEMPAS - 0,5 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE----[1] 86 💬
75ADEMPAS - 1 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE----[2] 51, 86 💬
76ADEMPAS - 1,5 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE----[2] 51, 86 💬
77ADEMPAS - 2 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE----[2] 51, 86 💬
78ADEMPAS - 2,5 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PP/ALU) - 42 COMPRESSE----[2] 51, 86 💬
79Adempas 0.5 mg----[2] 86, 299 💬
80Adempas 0.5 mg Film Coated Tablet----[1] 86 💬
81Adempas 1 mg Film Coated Tablet----[1] 86 💬
82Adempas 1.0 mg----[2] 86, 299 💬
83Adempas 1.5 mg----[1] 86 💬
84Adempas 1.5 mg Film Coated Tablet----[1] 86 💬
85Adempas 2 mg Film Coated Tablet----[1] 86 💬
86Adempas 2.0 mg----[2] 86, 299 💬
87Adempas 2.5 mg----[1] 86 💬
88Adempas 2.5 mg Film Coated Tablet----[1] 86 💬
89Adempas Filmtabletten----[1] 86 💬
90Adempas®----[2] 86, 88 💬
91Adempas® 0.5 mg film-coated tablets----[1] 86 💬
92Adempas® 1.0 mg film-coated tablets----[1] 86 💬
93Adempas® 1.5 mg film-coated tablets----[1] 86 💬
94Adempas® 2.0 mg film-coated tablets----[1] 86 💬
95Adempas® 2.5 mg film-coated tablets----[1] 86 💬
96Adempas¿ 0.5 mg compressa rivestita con film----[1] 86 💬
97Adempas¿ 1.0----[1] 86 💬
98Adempas¿ 1.5 mg----[1] 86 💬
99Adempas¿ 2.0 mg----[1] 86 💬
100Adempas¿ 2.5 mg----[1] 86 💬
101Adipose derived mesenchymal stem cells----[1] 86 💬
102AER-901 Solution for Nebulization----[1] 86 💬
103Aerosolized iloprost[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
104AIR001----[1] 86 💬
105AIR001 (sodium nitrite inhalation solution)[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[1] 86 💬
106AIR001 Inhalation Solution----[1] 86 💬
107AIR001 Inhalation Solution (Expansion arm)----[1] 86 💬
108Albuterol[1] Albuterol[2] Albuterol sulfate ,
Albuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
109Albuterol.[1] Albuterol[2] Albuterol sulfate ,
Albuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
110Allogeneic Human Cardiosphere-Derived Stem Cells----[1] 86 💬
111Ambrisentan[1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 51, 66, 84, 85, 86, 88, 210, 211, 218, 222 💬
112Ambrisentan - high dose[1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
113Ambrisentan - low dose[1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
114Ambrisentan 5 mg film-coated tablets[1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
115Ambrisentan 5mg film-coated tablets [marketed product][1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
116Ambrisentan mimic[1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
117Ambrisentan plus Spironolactone[2] Ambrisentan,
Spironolactone		[2] Spironolactone ,
Ambrisentan 💬 		[2] EDNRA,
NR3C2 💬 		[8] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
118Ambrisentan Tablet[1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
119Ammonia[1] Ammonia[1] Ammonia solution, strong 💬 --[6] 6, 17, 86, 88, 251, 296 💬
120AMN107----[2] 34, 86 💬
121Anakinra[1] Anakinra[1] Anakinra 💬 [2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
122ANASTROZOLE[1] Anastrozole[1] Anastrozole 💬 [1] CYP19A1 💬 [2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193 💬
123Apabetalone[1] Apabetalone[1] Apabetalone 💬 --[1] 86 💬
124APD811----[1] 86 💬
125Apelin[1] Apelin---[1] 86 💬
126APL-9796----[1] 86 💬
127AR392830----[1] 86 💬
128Artesunate[1] Artesunate[1] Artesunate 💬 --[4] 18, 66, 86, 96 💬
129Aspirin[1] Acetylsalicylic acid[1] Aspirin 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 22, 34, 48, 49, 51, 63, 86, 158, 210, 231 💬
130Assigned pulmonary hypertension medication----[1] 86 💬
131AV-101[1] AV-101---[2] 6, 86 💬
132AV-101Pharmaceutical Form: Inhalation powder, hard capsuleINN or Proposed INN: ImatinibCAS Number: 152459-95-5Current Sponsor code: AV-101Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 5-Product Name: AV-101Pharmaceutical Form: Inhalation powder, hard capsuleINN or Proposed INN: ImatinibCAS Number: 152459-95-5Current Sponsor code: AV-101Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 17.5-Product Name: AV-101Pharmaceutical Form: Inhalation powder, hard capsuleINN or Proposed INN: ImatinibCAS Number: 152459-95-5Current Sponsor code: AV-101Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 35-----[1] 86 💬
133Aviptadil[1] Aviptadil[1] Aviptadil 💬 --[4] 49, 51, 84, 86 💬
134Axially Oscillating Sphere dry powder inhaler (AOS DPI)----[1] 86 💬
135AZD4831----[1] 86 💬
136Background PAH Therapy----[1] 86 💬
137Bardoxolone[1] Bardoxolone[1] Bardoxolone 💬 --[7] 66, 67, 84, 85, 86, 218, 222 💬
138Bardoxolone methyl[2] Bardoxolone,
Bardoxolone methyl		[2] Bardoxolone ,
Bardoxolone methyl 💬 		--[7] 66, 67, 84, 85, 86, 218, 222 💬
139Bardoxolone methyl capsules[2] Bardoxolone,
Bardoxolone methyl		[2] Bardoxolone ,
Bardoxolone methyl 💬 		--[4] 66, 67, 86, 222 💬
140BARDOXOLONE METHYL, CDDO-Me, CDDO-Methyl Ester, NSC 713200, Chemical Name: Oleana-1,9(11)-dien-28-oic acid, 2-cyano-3,12-dioxo-, methyl ester[2] Bardoxolone,
Bardoxolone methyl		[2] Bardoxolone ,
Bardoxolone methyl 💬 		--[1] 86 💬
141BAY 63-2521----[2] 86, 88 💬
142BAY 63-2521 0.06 %----[1] 86 💬
143BAY 63-2521 0.3 %----[1] 86 💬
144BAY 63-2521 coated tablets 0.5 mg----[2] 86, 88 💬
145BAY 63-2521 coated tablets 1 mg----[2] 86, 88 💬
146BAY 63-2521 coated tablets 1.5 mg----[2] 86, 88 💬
147BAY 63-2521 coated tablets 2 mg----[2] 86, 88 💬
148BAY 63-2521 coated tablets 2.5 mg----[2] 86, 88 💬
149BAY 63-2521 IR tablets 0.5 mg----[1] 86 💬
150BAY 63-2521 IR tablets 1 mg----[1] 86 💬
151BAY 63-2521 IR tablets 1.0 mg----[1] 86 💬
152BAY 63-2521 IR tablets 1.5 mg----[1] 86 💬
153BAY 63-2521 IR tablets 2.0 mg----[1] 86 💬
154BAY 63-2521 IR tablets 2.5 mg----[1] 86 💬
155BAY 63-2521 Tablet----[1] 86 💬
156BAY 63-2521 tablets 0.5 mg----[2] 86, 88 💬
157BAY 63-2521 tablets 1 mg----[2] 86, 88 💬
158BAY 63-2521 tablets 1.5 mg----[2] 86, 88 💬
159BAY 63-2521 tablets 2 mg----[2] 86, 88 💬
160BAY 63-2521 tablets 2.5 mg----[2] 86, 88 💬
161Bay Q 6256----[1] 86 💬
162BAY1237592----[2] 86, 88 💬
163BAY63-2521----[3] 51, 86, 299 💬
164Beetroot juice----[2] 67, 86 💬
165Behavioral: 24 hour diet recall----[1] 86 💬
166Behavioral: Activity monitoring----[1] 86 💬
167Behavioral: E-learning----[1] 86 💬
168Behavioral: International Physical Activity Questionnaire Short Form (IPAQ-SF)----[1] 86 💬
169Behavioral: Low resistance exercise intervention----[1] 86 💬
170Behavioral: passive leg raising----[1] 86 💬
171Behavioral: Quality of Life Questionnaire (emPHasis 10)----[1] 86 💬
172Benzbromaron----[1] 86 💬
173Benzbromaron AL----[1] 86 💬
174BENZBROMARONE[1] Benzbromarone[1] Benzbromarone 💬 --[1] 86 💬
175Beraprost[1] Beraprost[2] Beraprost sodium ,
Beraprost 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
176Beraprost Sodium[1] Beraprost[2] Beraprost sodium ,
Beraprost 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
177Beraprost Sodium 314d Modified Release Tablets[1] Beraprost[2] Beraprost sodium ,
Beraprost 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
178Beraprost Sodium Modified Release[1] Beraprost[2] Beraprost sodium ,
Beraprost 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
179Bevacizumab[1] Bevacizumab[1] Bevacizumab 💬 [1] VEGFA 💬 [24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
180BIA[1] BIA---[4] 6, 86, 96, 299 💬
181BIA 5-1058[1] BIA---[1] 86 💬
182BIA 5-1058 and Furosemide[2] BIA,
Furosemide		[1] Furosemide 💬 [1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[1] 86 💬
183BIA-5-1058[1] BIA---[1] 86 💬
184Biological DMARDs----[2] 86, 107 💬
185Bisoprolol[1] Bisoprolol[2] Bisoprolol fumarate ,
Bisoprolol 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 57, 58, 67, 86, 113 💬
186Blood sampling----[15] 2, 3, 13, 14, 17, 46, 51, 64, 86, 96, 97, 98, 106, 162, 300 💬
187Bosentan[1] Bosentan[2] Bosentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
188Bosentan administration[1] Bosentan[2] Bosentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
189Bosentan Dispersible Tablets[1] Bosentan[2] Bosentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
190Bosentan monohydrat[1] Bosentan[2] Bosentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
191BOSENTAN MONOHYDRATE[1] Bosentan[2] Bosentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 84, 86, 88 💬
192Bosentan, Ambrisentan[2] Ambrisentan,
Bosentan		[3] Bosentan ,
Ambrisentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
193BPS-314d-MR----[1] 86 💬
194BPS-MR----[1] 86 💬
195Breelib nebulizer----[1] 86 💬
196Bromure d'Ipratropium[1] Ipratropium---[1] 86 💬
197BSF 208075----[1] 86 💬
198BSF 208075 or LU 208075----[1] 86 💬
199C07AB07----[1] 86 💬
200C225----[2] 51, 86 💬
201Calcifediol[1] Calcifediol[1] Calcifediol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 86, 113 💬
202Calcifediol Oral Capsule[1] Calcifediol[1] Calcifediol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 86 💬
203Capsaicin[1] Capsaicin[1] Capsaicin 💬 [1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226 💬
204Captopril[1] Captopril[1] Captopril 💬 [1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[3] 17, 57, 86 💬
205Carbon monoxide[1] Carbon monoxide[1] Carbon monoxide 💬 --[3] 85, 86, 298 💬
206CardioMEMS pulmonary artery pressure monitor----[1] 86 💬
207Carvedilol[1] Carvedilol[2] Carvedilol ,
Carvedilol phosphate 💬 		[5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		[15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 46, 57, 58, 86, 113, 210 💬
208Cetuximab[1] Cetuximab[1] Cetuximab 💬 [1] EGFR 💬 [49] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬[5] 34, 51, 86, 89, 331 💬
209Chenodeoxycholic acid[1] Chenodeoxycholic acid[1] Chenodiol 💬 [1] NR1H4 💬 [1] Bile secretion 💬[5] 20, 86, 96, 234, 263 💬
210Chlorhexidine[1] Chlorhexidine[4] Chlorhexidine gluconate ,
Chlorhexidine hydrochloride ,
Chlorhexidine ,
Chlorhexidine acetate 💬 		--[2] 86, 299 💬
211Cialis----[2] 51, 86 💬
212Cialis 10 mg film-coated tablets----[2] 86, 113 💬
213Cialis 2.5 mg film-coated tablets----[2] 86, 113 💬
214CIALIS 20 mg comprimidos recubiertos con película----[1] 86 💬
215Cialis 20 mg film-coated tablets----[2] 86, 113 💬
216Cialis 5 mg film-coated tablets----[2] 86, 113 💬
217Cicletanine[1] Cicletanine[2] Cicletanine ,
Cicletanine hydrochloride 💬 		--[1] 86 💬
218Cicletanine hydrochloride[1] Cicletanine[2] Cicletanine ,
Cicletanine hydrochloride 💬 		--[1] 86 💬
219Citrulline[1] Citrulline[2] L-Citrulline ,
Citrulline malate 💬 		--[3] 21, 86, 113 💬
220CJNJ-68150420-ZZZ-G001 (ACT- 064992D)----[1] 86 💬
221CJNJ-68150420-ZZZ-G001 (ACT-064992D)----[1] 86 💬
222CJNJ-68150420-ZZZ-G001(ACT-064992D)----[1] 86 💬
223Clopidogrel[1] Clopidogrel[4] Clopidogrel bisulfate ,
Clopidogrel ,
Clopidogrel hydrochloride ,
Clopidogrel besilate 💬 		[1] P2RY12 💬 [3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬[7] 40, 49, 51, 62, 71, 86, 222 💬
224Coenzyme Q-10 in Normal Control subjects----[1] 86 💬
225Coenzyme Q-10 in Pulmonary Hypertension subjects----[1] 86 💬
226Combination Product:----[1] 86 💬
227Combination Product: Implantable System for Remodulin (treprostinil)[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
228Combination Product: Treprostinil via implanted pump[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
229Commercial Ventavis® (iloprost)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
230Confirm Rx----[1] 86 💬
231Conivaptan[1] Conivaptan[2] Conivaptan hydrochloride ,
Conivaptan 💬 		[2] AVPR1A,
AVPR2 💬 		[6] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 86 💬
232Conventional drug therapy(expectorant,bronchodilator)----[1] 86 💬
233Crono Five ambulatory pump----[1] 86 💬
234CS1----[1] 86 💬
235CS1 Administration----[1] 86 💬
236Current marketed FLOLAN (epoprostenol sodium)[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
237CXA-10[1] CXA-10---[2] 86, 222 💬
238D-glucose[1] D-glucose[1] Glucose 💬 --[3] 49, 86, 88 💬
239D.3.6.2 - dose massima specificare: giornaliera----[1] 86 💬
240Dapagliflozin[1] Dapagliflozin[1] Dapagliflozin 💬 --[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
241Dapagliflozin 10 MG [Farxiga][1] Dapagliflozin[1] Dapagliflozin 💬 --[2] 86, 88 💬
242DHEA tablet----[1] 86 💬
243DIAG723----[2] 86, 227 💬
244Diagnostic Test: 18F-FAPI-74 PET/CT Imaging----[1] 86 💬
245Diagnostic Test: 18F-FGLN PET Imaging----[1] 86 💬
246Diagnostic Test: Blood draw----[8] 34, 65, 85, 86, 96, 97, 240, 299 💬
247Diagnostic Test: Cardiac MRI (Gadolinium enhanced)[1] Gadolinium---[1] 86 💬
248Diagnostic Test: CMRI----[2] 51, 86 💬
249Diagnostic Test: Echocardiogram----[2] 19, 86 💬
250Diagnostic Test: Endogenous thrombin potential[1] Thrombin[1] Thrombin 💬 --[2] 86, 88 💬
251Diagnostic Test: Grip strength test----[1] 86 💬
252Diagnostic Test: Light transmission aggregometry----[2] 86, 88 💬
253Diagnostic Test: Optional Muscle Biopsy----[1] 86 💬
254Diagnostic Test: PET-CT Imaging with [89Zr]-bevacizumab[1] Bevacizumab[1] Bevacizumab 💬 [1] VEGFA 💬 [24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[1] 86 💬
255Diagnostic Test: Platelet function analyzer-100----[2] 86, 88 💬
256Diagnostic Test: Right Heart Catheterization (RHC) while exercising----[1] 86 💬
257Diagnostic Test: Rotational thromboelastometry----[2] 86, 88 💬
258Diagnostic Test: Short Performance Physical Battery----[1] 86 💬
259Diagnostic Test: Six minute walk test----[1] 86 💬
260Dichloroacetate Sodium----[1] 86 💬
261Diet----[5] 86, 95, 97, 240, 299 💬
262Dietanolamina de treprostinilo[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
263Diethanolamine[1] Diethanolamine[1] Diethanolamine 💬 --[2] 51, 86 💬
264Diltiazem[1] Diltiazem[3] Diltiazem hydrochloride ,
Diltiazem malate ,
Diltiazem 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 58, 86, 88 💬
265Diltiazem Hydrochloride[1] Diltiazem[3] Diltiazem hydrochloride ,
Diltiazem malate ,
Diltiazem 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
266DIMETHYL FUMARATE[1] Dimethyl fumarate[1] Dimethyl fumarate 💬 [1] KEAP1 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 20, 51, 86, 296 💬
267Dimethyl Fumarate (DMF)[1] Dimethyl fumarate[1] Dimethyl fumarate 💬 [1] KEAP1 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[3] 13, 51, 86 💬
268Diphenhydramine[1] Diphenhydramine[4] Diphenhydramine ,
Diphenhydramine hydrochloride ,
Diphenhydramine salicylate ,
Diphenhydramine citrate 💬 		[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
269Dobutamine[1] Dobutamine[3] Dobutamine hydrochloride ,
Dobutamine ,
Dobutamine tartrate 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 28, 57, 58, 86, 215 💬
270Dobutamine test[1] Dobutamine[3] Dobutamine hydrochloride ,
Dobutamine ,
Dobutamine tartrate 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
271Dose A KER-012----[1] 86 💬
272Dose B KER-012----[1] 86 💬
273Dose C KER-012----[1] 86 💬
274Duo-Therapy with Sildenafil + Bosentan[2] Bosentan,
Sildenafil		[4] Bosentan ,
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
275EFI/ACT-385781A----[1] 86 💬
276Elafin[1] Elafin---[1] 86 💬
277EMEA/H/C/002677----[1] 86 💬
278Empagliflozin[1] Empagliflozin[1] Empagliflozin 💬 --[17] 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
279Empagliflozin 10 MG[1] Empagliflozin[1] Empagliflozin 💬 --[4] 58, 67, 86, 97 💬
280Empagliflozin in treatment pulmonary aerterial hypertension[1] Empagliflozin[1] Empagliflozin 💬 --[1] 86 💬
281Endothelin receptor antagonist therapy----[1] 86 💬
282Endothelin Receptor Antagonists----[1] 86 💬
283Endothelin-3----[1] 86 💬
284ENOS transfected EPCs will be delivered via a PA line----[1] 86 💬
285Epicatechin[1] Epicatechin---[2] 86, 113 💬
286EPOPROSTENOL[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
287Epoprostenol for injection[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
288EPOPROSTENOL SODICO[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
289EPOPROSTENOL SODIUM[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
290Epoprostenol-Actelion[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
291Epoprostenolo per iniezione----[1] 86 💬
292ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[6] Bosentan ,
Tadalafil ,
Sildenafil citrate ,
Bosentan ,
Sildenafil ,
Macitentan 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
293ERA as specific PAH treatment----[1] 86 💬
294Erbitux----[3] 51, 86, 121 💬
295Esomeprazole[1] Esomeprazole[5] Esomeprazole magnesium ,
Esomeprazole sodium ,
Esomeprazole ,
Esomeprazole strontium ,
Esomeprazole magnesium dihydrate 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
296ESR-specific PET scan----[1] 86 💬
297Esuberaprost[1] Esuberaprost[2] Esuberaprost ,
Esuberaprost sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
298Eutonic Treprostinil Solution[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
299Famotidine[1] Famotidine[1] Famotidine 💬 [1] HRH2 💬 [4] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[7] 6, 46, 86, 98, 107, 145, 300 💬
300Famotidine 20 MG[1] Famotidine[1] Famotidine 💬 [1] HRH2 💬 [4] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 86 💬
301FDC macitentan/tadalafil[2] Macitentan,
Tadalafil		[2] Tadalafil ,
Macitentan 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
302Ferinject----[3] 86, 97, 299 💬
303Ferinject or CosmoFer----[1] 86 💬
304FERRIC CARBOXYMALTOSE[1] Ferric carboxymaltose[1] Ferric carboxymaltose 💬 --[4] 86, 96, 97, 299 💬
305Ferricarboxymaltose----[1] 86 💬
306FK506 level 2-3 ng/ml----[1] 86 💬
307FK506 level 3-5 ng/ml----[1] 86 💬
308FK506 level < 2 ng/ml----[1] 86 💬
309FLOLAN injection with currently marketed diluent----[1] 86 💬
310FLOLAN injection with reformulated diluent----[1] 86 💬
311FLOLAN TM and Glycine Diluent[1] Glycine[1] Glycine 💬 --[1] 86 💬
312Flolan®----[1] 86 💬
313FLOLAN™ and Glycine Diluent[1] Glycine[1] Glycine 💬 --[1] 86 💬
314FLUOXETINE[1] Fluoxetine[2] Fluoxetine ,
Fluoxetine hydrochloride 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 13, 17, 86 💬
315Forxiga----[4] 86, 88, 222, 223 💬
316Forxiga (dapagliflozin)[1] Dapagliflozin[1] Dapagliflozin 💬 --[2] 86, 88 💬
317Frespaciguat[1] Frespaciguat---[1] 86 💬
318Fulvestrant[1] Fulvestrant[1] Fulvestrant 💬 [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 86 💬
319Furosemide[1] Furosemide[1] Furosemide 💬 [1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[5] 6, 57, 77, 86, 222 💬
320G04BE03----[1] 86 💬
321G04BE03- Sildenafil - sildenafil (citrato)[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
322G04BE08----[1] 86 💬
323Gadolinium[1] Gadolinium---[8] 13, 34, 46, 65, 77, 86, 113, 305 💬
324GB002----[1] 86 💬
325GB002 (seralutinib)[1] Seralutinib[1] Seralutinib 💬 [2] PDGFRA,
PDGFRB 💬 		[22] Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Focal adhesion, Gap junction, Glioma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬[1] 86 💬
326GB002 Capsules----[1] 86 💬
327Generic Dry Powder Inhaler----[1] 86 💬
328Generic treprostinil sodium + Standard of Care (Double Oral)[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
329Genetic: Saliva sample----[2] 86, 88 💬
330Genetic: targeted gene panels analysis----[1] 86 💬
331Genetic: whole genome analysis----[1] 86 💬
332Gereic Dry Powder Inhaler----[1] 86 💬
333GLIVEC----[2] 51, 86 💬
334GLIVEC 100 mg comprimidos recubiertos con película----[2] 34, 86 💬
335Glivec 100 mg Filmtabletten----[2] 51, 86 💬
336Glivec 100 mg Hartkapsel----[1] 86 💬
337Glivec®----[1] 86 💬
338Glivec® 100 mg Filmtabletten----[1] 86 💬
339GLYCINE[1] Glycine[1] Glycine 💬 --[7] 35, 60, 86, 226, 247, 299, 340 💬
340GMA301 Injection----[1] 86 💬
341Gold[1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
342GS-4997 18 mg----[1] 86 💬
343GS-4997 2 mg----[1] 86 💬
344GS-4997 6 mg----[1] 86 💬
345GSK1325760----[2] 86, 88 💬
346GSK1325760A----[1] 86 💬
347GSK2256098[1] GSK2256098---[1] 86 💬
348GSK2586881----[1] 86 💬
349HGP1206----[1] 86 💬
350HS135----[1] 86 💬
351HS235----[1] 86 💬
352Hydroxyurea[1] Hydroxyurea[1] Hydroxyurea 💬 [1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
353Hyperpolarized 129Xe----[1] 86 💬
354Hyperpolarized 13C-pyruvate----[1] 86 💬
355Hyperpolarized Xe129----[5] 51, 85, 86, 88, 299 💬
356HypotonicTreprostinil Solution----[1] 86 💬
357I-Neb AAD system----[1] 86 💬
358I.v. selexipag[1] Selexipag[1] Selexipag 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
359Ifetroban[1] Ifetroban[2] Ifetroban ,
Ifetroban sodium 💬 		[1] TBXA2R 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[4] 51, 85, 86, 113 💬
360IKT-001----[1] 86 💬
361IKT-001Pro[1] IKT-001Pro---[1] 86 💬
362Ilomedin 20----[1] 86 💬
363Ilomedin 20 [20 µg / ml]----[1] 86 💬
364Iloprost[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[4] 51, 84, 85, 86 💬
365Iloprost (5 µg)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
366Iloprost (Ventavis BAYQ6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
367Iloprost (Ventavis inhaled, BAYQ6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
368Iloprost (Ventavis, BAYQ 6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
369Iloprost (Ventavis, BAYQ6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
370Iloprost (Ventavis®)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
371Iloprost Inhalation Solution (Ventavis)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[2] 85, 86 💬
372Iloprost PD-15[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
373Iloprost PD-6[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
374Iloprost,(Ventavis, BAYQ6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
375Imatinib[1] Imatinib[2] Imatinib mesylate ,
Imatinib 💬 		[3] ABL1,
KIT,
PDGFRA 💬 		[34] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
376IMATINIB MESILATE[1] Imatinib[2] Imatinib mesylate ,
Imatinib 💬 		[3] ABL1,
KIT,
PDGFRA 💬 		[34] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[3] 13, 86, 88 💬
377Imatinib Mesylate[1] Imatinib[2] Imatinib mesylate ,
Imatinib 💬 		[3] ABL1,
KIT,
PDGFRA 💬 		[34] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 13, 28, 34, 51, 86 💬
378IMC-003 and PAH background therapy----[1] 86 💬
379Inhaled dry powder treprostinil (LIQ861)[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
380Inhaled Iloprost (5 µg)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
381Inhaled iloprost (Ventavis, BAYQ6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
382Inhaled Nitric Oxide[1] Nitric Oxide[1] Nitric oxide 💬 --[3] 85, 86, 294 💬
383Inhaled nitric oxide & INOpulse delivery[1] Nitric Oxide[1] Nitric oxide 💬 --[1] 86 💬
384Inhaled nitric oxide 75 mcg/kg IBW/hr[1] Nitric Oxide[1] Nitric oxide 💬 --[2] 85, 86 💬
385Inhaled NO with pulsed delivery----[1] 86 💬
386Inhaled prostacyclin----[1] 86 💬
387Inhaled Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[3] 84, 85, 86 💬
388INO----[2] 85, 86 💬
389INS1009----[1] 86 💬
390Intestinal microbiota transplant (IMT)----[1] 86 💬
391Intravenous administration of ferric carboxymaltose[1] Ferric carboxymaltose[1] Ferric carboxymaltose 💬 --[1] 86 💬
392Intravenous Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
393Intravenous/Subcutaneous Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
394Ipratropium[1] Ipratropium---[2] 6, 86 💬
395Iron supplement----[1] 86 💬
396Jardiance----[2] 65, 86 💬
397JNJ-67896049----[1] 86 💬
398JNJ-67896049 (ACT-293987)----[1] 86 💬
399JNJ-67896062 / ACT-064992----[2] 86, 88 💬
400JNJ-67896062/ACT-064922----[1] 86 💬
401JTT-251[1] JTT-251---[1] 86 💬
402KAR5585 Capsules----[1] 86 💬
403L-Carnitine----[5] 13, 46, 86, 96, 240 💬
404L-Citrulline Malate[1] Citrulline[2] L-Citrulline ,
Citrulline malate 💬 		--[1] 86 💬
405L01XE01----[1] 86 💬
406L606 (Liposomal Treprostinil) Inhalation Solution 51ug[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
407L606 Inhalation System----[1] 86 💬
408L608 Inhalation Solution----[1] 86 💬
409L608 Liposomal inhalation suspension----[1] 86 💬
410Levitra----[2] 13, 86 💬
411Lidocaine[1] Lidocaine[3] Lidocaine ,
Lidocaine hydrochloride ,
Lidocaine hydrochloride monohydrate 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
412LIQ861 100 µg----[1] 86 💬
413LIQ861 106 µg----[1] 86 💬
414LIQ861 25 µg----[1] 86 💬
415LIQ861 26.5 µg----[1] 86 💬
416LIQ861 50 µg----[1] 86 💬
417LIQ861 53 µg----[1] 86 💬
418LIQ861 75 µg----[1] 86 💬
419LIQ861 79.5 µg----[1] 86 💬
420LIQ861 Inhaled Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
421LISURIDE[1] Lisuride[1] Lisuride 💬 [3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86 💬
422Lloprost(Ventavis,BAYQ6252, 10 µg/mL)----[1] 86 💬
423Lloprost(Ventavis,BAYQ6252, 20 µg/mL)----[1] 86 💬
424LTP----[1] 86 💬
425LTP001----[2] 85, 86 💬
426LY450190----[1] 86 💬
427Macitentan[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 51, 85, 86, 88, 210 💬
428Macitentan (ACT-064992)[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
429Macitentan 10 mg[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 86, 88 💬
430Macitentan 10 mg tablet, once daily.[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
431Macitentan 37.5 mg[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
432Macitentan 75 mg[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
433MACITENTAN COMPRESSE[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
434Macitentan Group[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
435MACITENTAN TABLETS[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
436Medical air[1] Medical air[1] Air, medical 💬 --[3] 85, 86, 193 💬
437Melatonin[1] Melatonin[1] Melatonin 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
438Metformin[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
439Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo----[1] 86 💬
440Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo [3,4-b]pyridine-3-yl]-5-pyrimidinyl(methyl)carb----[2] 86, 88 💬
441Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]meth----[2] 86, 88 💬
442Methylprednisolone[1] Methylprednisolone[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
443MHealth Intervention----[1] 86 💬
444MK-4836----[2] 86, 88 💬
445MK-5475----[1] 86 💬
446MK-7962----[1] 86 💬
447MK-8892----[1] 86 💬
448MN-08 24 mg/day----[1] 86 💬
449MN-08 60 mg/day----[1] 86 💬
450Mono-Therapy with Sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
451Morphine[1] Morphine[4] Morphine sulfate ,
Morphine hydrochloride hydrate ,
Morphine ,
Morphine tartrate 💬 		[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
452MORPHINE SULFATE[1] Morphine[4] Morphine sulfate ,
Morphine hydrochloride hydrate ,
Morphine ,
Morphine tartrate 💬 		[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 46, 85, 86 💬
453Moxifloxacin[1] Moxifloxacin[3] Moxifloxacin hydrochloride ,
Moxifloxacin ,
Moxifloxacin hydrochloride monohydrate 💬 		--[10] 2, 6, 46, 49, 85, 86, 113, 226, 240, 299 💬
454Moxifloxacin 400 mg[1] Moxifloxacin[3] Moxifloxacin hydrochloride ,
Moxifloxacin ,
Moxifloxacin hydrochloride monohydrate 💬 		--[1] 86 💬
455MTT with antibiotic preconditioning----[1] 86 💬
456MTT with antibiotic preconditioning + fiber supplementation----[1] 86 💬
457MultiHance----[2] 86, 88 💬
458Nab-sirolimus (also known as ABI-009, nab-rapamycin, albumin-bound rapamycin)[1] Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 86 💬
459Nebulized combination ipratropium bromide with salbutamol[1] Ipratropium---[1] 86 💬
460Nebulized ipratropium bromide[1] Ipratropium---[1] 86 💬
461Nebulized nitroglycerin[1] Nitroglycerin[1] Nitroglycerin 💬 --[1] 86 💬
462New thermo stable formulation of epoprostenol sodium[1] Epoprostenol[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
463Nicardipine[1] Nicardipine[2] Nicardipine hydrochloride ,
Nicardipine 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 70, 86 💬
464Nilotinib[1] Nilotinib[1] Nilotinib 💬 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬 		[35] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86 💬
465Nilotinib 50 mg[1] Nilotinib[1] Nilotinib 💬 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬 		[35] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[1] 86 💬
466Nitric Oxide[1] Nitric Oxide[1] Nitric oxide 💬 --[12] 46, 51, 85, 86, 88, 97, 98, 210, 251, 294, 299, 340 💬
467Nitric Oxide for inhalation[1] Nitric Oxide[1] Nitric oxide 💬 --[2] 86, 299 💬
468Nitric Oxide generated by the GeNO nitrosyl delivery system[1] Nitric Oxide[1] Nitric oxide 💬 --[1] 86 💬
469Nitric Oxide plus Oxygen[2] Nitric Oxide,
Oxygen		[2] Oxygen ,
Nitric oxide 💬 		--[1] 86 💬
470Nitrite[1] Nitrite---[3] 58, 86, 299 💬
471Nitroglycerin[1] Nitroglycerin[1] Nitroglycerin 💬 --[2] 51, 86 💬
472Non-Biologic DMARDs----[3] 46, 86, 107 💬
473NS-304----[1] 86 💬
474NS-863 High Dose----[1] 86 💬
475NS-863 Low Dose----[1] 86 💬
476NX1011----[1] 86 💬
477Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi----[1] 86 💬
478Olaparib[1] Olaparib[1] Olaparib 💬 [2] PARP1,
PARP2 💬 		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285 💬
479Opsumit----[2] 86, 88 💬
480Opsumit (macitentan)[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
481Opsumit®----[3] 86, 88, 210 💬
482Opsumit®Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992Pharmaceutical Form: Film-coated tabletINN or Proposed INN: MACITENTANCAS Number: 441798-33-0Current Sponsor code: JNJ-67896062-AAAOther descriptive name: ACT-064992Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 10-Pharmaceutical form of the placebo: Film-coated tabletRoute of administration of the placebo: Oral useProduct Name: Macitentan tabletsProduct Code: JNJ-67896062 / ACT-064992Pharmaceutical Form: Film-coated tabletINN or Proposed INN: MACITENTANCAS Number: 441798-33-0Current Sponsor code: JNJ-67896062-AAAOther descriptive name: ACT-064992Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 75-Pharmaceutical form of the placebo: Film-coated tabletRoute of administration of the placebo: Oral useProduct Name: Macitentan tabletsProduct Code: JNJ-67896062 / ACT-064992Pharmaceutical Form: Film-coated tabletINN or Proposed INN: MACITENTANCAS Number: 441798-33-0Current Sponsor code: JNJ-67896062-AAAOther descriptive name: ACT-064992Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 37.5-Pharmaceutical form of the placebo: Film-coated tabletRoute of administration of the placebo: Oral use[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
483Opsumit®Product Name: macitentan tabletsProduct Code: JNJ-67896062 / ACT-064992Pharmaceutical Form: Film-coated tabletINN or Proposed INN: MACITENTANCAS Number: 441798-33-0Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 10-Pharmaceutical form of the placebo: Film-coated tabletRoute of administration of the placebo: Oral useProduct Name: macitentan tabletsProduct Code: JNJ-67896062 / ACT-064992Pharmaceutical Form: Film-coated tabletINN or Proposed INN: MACITENTANCAS Number: 441798-33-0Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 75-Pharmaceutical form of the placebo: Film-coated tabletRoute of administration of the placebo: Oral useProduct Name: macitentan tabletsProduct Code: JNJ-67896062 / ACT-064992Pharmaceutical Form: Film-coated tabletINN or Proposed INN: MACITENTANCAS Number: 441798-33-0Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 37.5-Pharmaceutical form of the placebo: Film-coated tabletRoute of administration of the placebo: Oral use[1] Macitentan[1] Macitentan 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
484Oral anticoagulant treatment----[1] 86 💬
485Oral ERA----[1] 86 💬
486Oral Ifetroban[1] Ifetroban[2] Ifetroban ,
Ifetroban sodium 💬 		[1] TBXA2R 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[2] 51, 86 💬
487Oral PDE5 inhibitors----[1] 86 💬
488Oral selexipag (Uptravi)[1] Selexipag[1] Selexipag 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
489Oral sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
490Oral treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[2] 51, 86 💬
491Oral treprostinil (UT-15C) Sustained Release Tablets[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
492Oral zamicastat[1] Zamicastat---[1] 86 💬
493Ossido Nitrico----[1] 86 💬
494Other: 6-minute walk distance (6MWD) test----[2] 86, 88 💬
495Other: 6-minute walk distance (6MWD) test on ambient air----[2] 86, 88 💬
496Other: 6-minute walk distance (6MWD) test with supplemental oxygen (3 l/min, nasal)[1] Oxygen[1] Oxygen 💬 --[2] 86, 88 💬
497Other: 6-minute walk distance test with supplemental oxygen[1] Oxygen[1] Oxygen 💬 --[2] 86, 88 💬
498Other: Blood draw----[17] 2, 6, 11, 13, 18, 39, 46, 57, 77, 84, 85, 86, 88, 96, 97, 167, 299 💬
499Other: Blood Gas----[1] 86 💬
500Other: Blood sample----[37] 2, 11, 13, 34, 35, 41, 44, 46, 48, 49, 50, 51, 53, 58, 61, 63, 65, 84, 86, 96, 97, 113, 160, 162, 177, 222, 223, 227, 234, 238, 240, 256, 279, 299, 335, 340, 348 💬
501Other: Blood Samples----[13] 3, 13, 46, 51, 53, 63, 85, 86, 88, 96, 98, 140, 193 💬
502Other: Blood test----[11] 10, 19, 46, 51, 57, 65, 66, 83, 86, 96, 113 💬
503Other: Breath Condensate Collector----[1] 86 💬
504Other: Cardiac MRI----[1] 86 💬
505Other: Health surveys----[2] 86, 88 💬
506Other: Iloprost (Ventavis inhaled, BAYQ6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
507Other: Noninvasive actigraphy monitor----[1] 86 💬
508Other: Pulmonary Exercise Test----[1] 86 💬
509Other: Sham Oxygen therapy[1] Oxygen[1] Oxygen 💬 --[2] 86, 88 💬
510Other: Spirometry----[2] 84, 86 💬
511Other: Standard-of-care----[1] 86 💬
512Other: Standardized meals----[1] 86 💬
513Other: Subacute hypoxic exposures----[1] 86 💬
514Other: Supplemental oxygen therapy[1] Oxygen[1] Oxygen 💬 --[2] 86, 88 💬
515Other: Switch from Ambrisentan to Bosentan[2] Ambrisentan,
Bosentan		[3] Bosentan ,
Ambrisentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
516Oxacom----[1] 86 💬
517Oxygen[1] Oxygen[1] Oxygen 💬 --[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
518Oxygen supplementation[1] Oxygen[1] Oxygen 💬 --[1] 86 💬
519Oxygen, liquid[1] Oxygen[1] Oxygen 💬 --[2] 86, 88 💬
520PADN----[1] 86 💬
521PAH background therapy----[1] 86 💬
522PAH medication----[1] 86 💬
523Parenteral Remodulin (treprostinil) injection[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
524Parenteral Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
525PB1046----[1] 86 💬
526PB1046 Subcutaneous Injection----[1] 86 💬
527PB1046, VIP-ELP1-120, Vasomera[1] Vasomera---[1] 86 💬
528PDE5 inhibitor----[1] 86 💬
529Pemziviptadil (PB1046) Injection----[1] 86 💬
530PF-00489791[1] PF-00489791---[1] 86 💬
531PF-07868489----[1] 86 💬
532Pioglitazone[1] Pioglitazone[2] Pioglitazone hydrochloride ,
Pioglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
533PLX-PAD[1] PLX-PAD---[1] 86 💬
534PNEUMOSTEM®----[1] 86 💬
535Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
536Preservative-free parenteral treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
537Prostacyclin----[1] 86 💬
538Prostacyclin Receptor Agonist----[1] 86 💬
539Puri-Nethol----[3] 86, 96, 97 💬
540Q4W GMA301 IV injections (1000 mg)----[1] 86 💬
541Q4W GMA301 IV injections (300 mg)----[1] 86 💬
542Q4W GMA301 IV injections (600 mg)----[1] 86 💬
543QCC374----[1] 86 💬
544QCC374 0.015 mg----[1] 86 💬
545QCC374 0.06 mg----[1] 86 💬
546QTI571----[1] 86 💬
547Qutenza----[1] 86 💬
548Qutenza (8% capsaicin)[1] Capsaicin[1] Capsaicin 💬 [1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 86 💬
549Radiation: Chest CT scan----[1] 86 💬
550Radiation: Dual-Energy X-ray Absorptiometry Scan----[1] 86 💬
551Radiation: magnetic resonance imaging----[2] 86, 88 💬
552Radiation: PET/CT Scan: Two PET scans using 1. C-11 HED and 2. N-13 Ammonia or rubidium-82[2] Ammonia,
Rubidium		[1] Ammonia solution, strong 💬 --[1] 86 💬
553RALINEPAG[1] Ralinepag[1] Ralinepag 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
554Ranolazine[1] Ranolazine[2] Ranolazine ,
Ranolazine hydrochloride 💬 		--[8] 2, 57, 58, 86, 96, 97, 113, 114 💬
555Rapid Dose Titration Group of Subcutaneous Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
556Recombinant Human Angiotensin-converting enzyme 2 (ACE2), APN01----[1] 86 💬
557REGN13335----[1] 86 💬
558Remodulin----[1] 86 💬
559Remodulin (treprostinil sodium)[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
560Remodulin® (treprostinil) 1 mg/ml solution for infusion[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
561Remodulin® (treprostinil) 10 mg/ml solution for infusion[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
562Remodulin® (treprostinil) 2.5 mg/ml solution for infusion[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
563Remodulin® (treprostinil) 5 mg/ml solution for infusion[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
564Revatio----[3] 85, 86, 113 💬
565Revatio 10 mg/ml powder for oral suspension----[1] 86 💬
566Revatio 20 mg film coated tablets----[1] 86 💬
567Revatio 20 mg film-coated tablets----[1] 86 💬
568Revatio 20 mg Filmtabletten----[1] 86 💬
569REVATIO 20 mg, comprimidos recubiertos con película----[1] 86 💬
570Revatio inyectable----[1] 86 💬
571Revatio oral----[1] 86 💬
572Revatio POS----[1] 86 💬
573Revatio Tablets----[1] 86 💬
574Revatio®----[1] 86 💬
575Riciguat Group----[1] 86 💬
576Rifampin[1] Rifampin[2] Rifampin ,
Rifampicin sodium 💬 		--[5] 6, 13, 84, 86, 299 💬
577RIOCIGUAT[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299 💬
578Riociguat (Adempas, BAY63-2521)[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 51, 86, 88, 299 💬
579Riociguat (BAY63-2521)[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
580Riociguat 0.5 mg[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
581Riociguat 1.0 mg[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
582Riociguat 1.5 mg[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
583Riociguat 2.0 mg[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
584Riociguat 2.5 mg[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
585Riociguat film coated tablets[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
586Riociguat granules 0.3% for oral application[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
587Riociguat Oral Product[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
588Riociguat Oral Tablet[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 51, 86, 88 💬
589Riociguat Pill[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
590Ritonavir[1] Ritonavir[1] Ritonavir 💬 --[3] 2, 86, 265 💬
591RITUXIMAB[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
592Ro 47-0203----[4] 51, 85, 86, 88 💬
593Ro-47-0203----[1] 86 💬
594Ro-47-0203/029----[1] 86 💬
595RoActemra----[7] 41, 44, 46, 51, 86, 107, 271 💬
596ROC-101----[1] 86 💬
597Rodatristat[1] Rodatristat[1] Rodatristat 💬 [1] TPH1 💬 [3] Folate biosynthesis, Serotonergic synapse, Tryptophan metabolism 💬[1] 86 💬
598Rodatristat ethyl[2] Rodatristat,
Rodatristat ethyl		[2] Rodatristat ,
Rodatristat ethyl 💬 		[1] TPH1 💬 [3] Folate biosynthesis, Serotonergic synapse, Tryptophan metabolism 💬[1] 86 💬
599Rodatristat ethyl 300 mg tablet BID[2] Rodatristat,
Rodatristat ethyl		[2] Rodatristat ,
Rodatristat ethyl 💬 		[1] TPH1 💬 [3] Folate biosynthesis, Serotonergic synapse, Tryptophan metabolism 💬[1] 86 💬
600Rodatristat ethyl 600 mg BID[2] Rodatristat,
Rodatristat ethyl		[2] Rodatristat ,
Rodatristat ethyl 💬 		[1] TPH1 💬 [3] Folate biosynthesis, Serotonergic synapse, Tryptophan metabolism 💬[1] 86 💬
601RS01 dry powder inhaler (RS01 DPI)----[1] 86 💬
602RT234 - vardenafil inhalation powder[1] Vardenafil[2] Vardenafil ,
Vardenafil hydrochloride 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
603RTA 402----[3] 67, 86, 218 💬
604Rubidium[1] Rubidium---[2] 84, 86 💬
605RVG 33865----[1] 86 💬
606RVT-1201----[1] 86 💬
607Salbutamol----[9] 2, 3, 11, 85, 86, 228, 256, 299, 340 💬
608Saline----[12] 2, 6, 13, 17, 18, 53, 67, 77, 86, 97, 168, 299 💬
609Sapropterin[1] Sapropterin[2] Sapropterin dihydrochloride ,
Sapropterin 💬 		--[3] 86, 124, 240 💬
610Sapropterin dihydrochloride (6R-BH4)[1] Sapropterin[2] Sapropterin dihydrochloride ,
Sapropterin 💬 		--[1] 86 💬
611Saquinavir[1] Saquinavir[2] Saquinavir ,
Saquinavir mesylate 💬 		--[4] 86, 222, 223, 265 💬
612Saquinavir and ritonavir[2] Ritonavir,
Saquinavir		[3] Ritonavir ,
Saquinavir ,
Saquinavir mesylate 💬 		--[1] 86 💬
613SATRALIZUMAB[1] Satralizumab[1] Satralizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 11, 13, 86, 113 💬
614Satralizumab (Genetical Recombination)[1] Satralizumab[1] Satralizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 86 💬
615Sauerstoff----[2] 86, 88 💬
616Selexipag[1] Selexipag[1] Selexipag 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 47, 51, 70, 84, 86, 88 💬
617Selexipag (Uptravi)[1] Selexipag[1] Selexipag 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
618Selexipag Film Coated Tablets[1] Selexipag[1] Selexipag 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
619Selexipag, ACT-293987 (NS-304)[1] Selexipag[1] Selexipag 💬 [1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
620Selonsertib[1] Selonsertib[1] Selonsertib 💬 [1] MAP3K5 💬 [19] Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Huntington disease, Lipid and atherosclerosis, MAPK signaling pathway, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Protein processing in endoplasmic reticulum, Sphingolipid signaling pathway, Spinocerebellar ataxia, TNF signaling pathway, Thermogenesis, Tight junction 💬[1] 86 💬
621Seralutinib[1] Seralutinib[1] Seralutinib 💬 [2] PDGFRA,
PDGFRB 💬 		[22] Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Focal adhesion, Gap junction, Glioma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬[1] 86 💬
622Serine[1] Serine[1] Serine 💬 --[5] 2, 6, 86, 96, 222 💬
623Sham O2 (medical air)[1] Medical air[1] Air, medical 💬 --[1] 86 💬
624Sham PADN----[1] 86 💬
625SILDENAF----[1] 86 💬
626Sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
627Sildenafil (as citrate)[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
628Sildenafil (Revatio) 20 mg TID[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
629Sildenafil 20mg[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
630Sildenafil 20mg and Bosentan 62.5mg[2] Bosentan,
Sildenafil		[4] Bosentan ,
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
631Sildenafil citrate[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225 💬
632Sildenafil citrate (UK-92,480)[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
633Sildenafil Filmtabletten[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
634Sildenafil singly or in association with Bosentan[2] Bosentan,
Sildenafil		[4] Bosentan ,
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
635SILDENAFILO[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
636Simvastatin[1] Simvastatin[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
637Simvastatin 40 mg[1] Simvastatin[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 86 💬
638Simvastatin 40 mg tablets[1] Simvastatin[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 86 💬
639Sirolimus[1] Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
640Sitaxentan[1] Sitaxentan[2] Sitaxentan ,
Sitaxentan sodium 💬 		[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
641Sitaxentan sodium[1] Sitaxentan[2] Sitaxentan ,
Sitaxentan sodium 💬 		[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
642Sitaxsentan[1] Sitaxentan[2] Sitaxentan ,
Sitaxentan sodium 💬 		[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
643Sitaxsentan alone----[1] 86 💬
644Sitaxsentan and Sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
645SITAXSENTAN SODIUM----[1] 86 💬
646Skin biopsy----[6] 6, 19, 21, 51, 84, 86 💬
647Slow Dose Titration Group of Subcutaneous Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
648SOC: Phosphodiesterase type 5 (PDE-5) inhibitor----[1] 86 💬
649SOC: Soluble guanylate cyclase stimulator----[1] 86 💬
650SODIUM NITRITE[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[2] 86, 299 💬
651Sodium Nitrite Inhalation Solution[2] Nitrite,
Nitrous acid		[1] Sodium nitrite 💬 --[1] 86 💬
652Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
653Sorafenib[1] Sorafenib[2] Sorafenib tosylate ,
Sorafenib 💬 		[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Cadherin signaling, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 34, 86 💬
654SOTATERCEPT[1] Sotatercept[1] Sotatercept 💬 [1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[2] 86, 284 💬
655Sotatercept - 45 mg/vial[1] Sotatercept[1] Sotatercept 💬 [1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 86 💬
656Sotatercept - 60 mg/vial[1] Sotatercept[1] Sotatercept 💬 [1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 86 💬
657Sotatercept - 60 mg/vialProduct Code: ACE-011 / MK-7962 Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962 Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg milligram(s)Concentration type: equalConcentration number: 72.5-Product Name: Sotatercept - 45 mg/vialProduct Code: ACE-011 / MK-7962 Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962 Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg milligram(s)Concentration type: equalConcentration number: 55-[1] Sotatercept[1] Sotatercept 💬 [1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 86 💬
658Sotatercept - 60 mg/vialProduct Code: ACE-011 / MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 72.5-Product Name: Sotatercept - 45 mg/vialProduct Code: ACE-011 / MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 55-[1] Sotatercept[1] Sotatercept 💬 [1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 86 💬
659Sotatercept 0.3 mg/kg escalating to 0.7 mg/kg[1] Sotatercept[1] Sotatercept 💬 [1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 86 💬
660SotaterceptProduct Code: ACE-011 / MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 50-Pharmaceutical form of the placebo: Lyophilisate for solution for injectionRoute of administration of the placebo: Subcutaneous use----[1] 86 💬
661SotaterceptProduct Code: ACE-011/MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011/MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 50-Pharmaceutical form of the placebo: Lyophilisate for solution for injectionRoute of administration of the placebo: Subcutaneous use----[1] 86 💬
662Spironolactone[1] Spironolactone[1] Spironolactone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
663Spironolactone and conivaptan[2] Conivaptan,
Spironolactone		[3] Spironolactone ,
Conivaptan hydrochloride ,
Conivaptan 💬 		[3] AVPR1A,
AVPR2,
NR3C2 💬 		[7] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 86 💬
664Spironolactone captopril carvedilol[3] Captopril,
Carvedilol,
Spironolactone		[4] Captopril ,
Carvedilol ,
Spironolactone ,
Carvedilol phosphate 💬 		[7] ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬 		[21] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hormone signaling, Hypertrophic cardiomyopathy, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
665Standard of Care (SOC): Endothelin receptor antagonist----[1] 86 💬
666Standard of Care - Double Oral----[1] 86 💬
667STI571----[2] 51, 86 💬
668Subcutaneous and intravenous prostacyclin----[1] 86 💬
669Subcutaneous Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
670Sugar pill----[9] 5, 6, 49, 67, 70, 86, 120, 206, 210 💬
671SULFASALAZINE[1] Sulfasalazine[1] Sulfasalazine 💬 --[7] 46, 49, 86, 94, 107, 270, 271 💬
672Tadalafil[1] Tadalafil[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[8] 6, 51, 75, 77, 84, 86, 113, 210 💬
673Tadalafil 20 mg film-coated tablets[1] Tadalafil[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
674Tadalafil 40 mg[1] Tadalafil[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
675Tadalafil and ambrisentan upfront combination therapy[2] Ambrisentan,
Tadalafil		[2] Tadalafil ,
Ambrisentan 💬 		[2] EDNRA,
PDE5A 💬 		[8] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
676Tadalafil mimic[1] Tadalafil[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
677Tadalafil oral suspension[1] Tadalafil[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
678Tadalafil- Tablet or Oral suspension[1] Tadalafil[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
679TADALAFILO[1] Tadalafil[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
680Tamoxifen[1] Tamoxifen[2] Tamoxifen citrate ,
Tamoxifen 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[6] 2, 65, 86, 113, 227, 299 💬
681Tasigna----[2] 34, 86 💬
682Tasigna®----[1] 86 💬
683Tasigna® 150 mg----[1] 86 💬
684TBD----[5] 19, 86, 90, 276, 299 💬
685Tegaderm----[1] 86 💬
686Terguride[1] Terguride[1] Terguride 💬 [2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 51, 86 💬
687Terguride 0,5mg tablet[1] Terguride[1] Terguride 💬 [2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 86 💬
688Terguride 0.5 mg tablet[1] Terguride[1] Terguride 💬 [2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 86 💬
689Tezosentan[1] Tezosentan---[1] 86 💬
690The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:[1] Whole Blood[1] Blood, whole 💬 --[1] 86 💬
691The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:----[1] 86 💬
692Thelin----[1] 86 💬
693Threonine[1] Threonine[1] Threonine 💬 --[3] 86, 96, 97 💬
694Thrombin[1] Thrombin[1] Thrombin 💬 --[3] 86, 88, 97 💬
695Tiprelestat[1] Tiprelestat---[1] 86 💬
696Tiprelestat (10 mg)[1] Tiprelestat---[1] 86 💬
697Tiprelestat (5 mg)[1] Tiprelestat---[1] 86 💬
698Tocilizumab[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
699TOLVAPTAN[1] Tolvaptan[1] Tolvaptan 💬 [1] AVPR2 💬 [4] Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[5] 67, 72, 86, 222, 225 💬
700TPN171H----[1] 86 💬
701TPN171H single dose----[1] 86 💬
702Traclear----[1] 86 💬
703Tracleer----[8] 13, 51, 84, 85, 86, 88, 210, 211 💬
704TRACLEER 62,5MG 56CPR RIV.----[1] 86 💬
705Tracleer Tablet for Oral Suspension----[1] 86 💬
706TRACLEER*125MG 56CPR RIV.----[2] 51, 86 💬
707TRACLEER*56CPR RIV 125MG----[3] 51, 86, 88 💬
708Tracleer®----[1] 86 💬
709Transdihydrolisuride----[2] 51, 86 💬
710TRE----[1] 86 💬
711Treprosinil Diethanolamine[1] Diethanolamine[1] Diethanolamine 💬 --[1] 86 💬
712Treprostin----[1] 86 💬
713Treprostinil[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210 💬
714Treprostinil dietanolamina[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
715Treprostinil diethanolamine[2] Diethanolamine,
Treprostinil		[4] Diethanolamine ,
Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[2] 51, 86 💬
716Treprostinil Diolamine[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
717Treprostinil Inhalation Powder[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
718Treprostinil inhalations[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
719Treprostinil Injectable Product[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
720TREPROSTINIL PALMITIL[2] Treprostinil,
Treprostinil palmitil		[4] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine ,
Treprostinil palmitil 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
721Treprostinil Palmitil Inhalation Powder[2] Treprostinil,
Treprostinil palmitil		[4] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine ,
Treprostinil palmitil 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
722Treprostinil palmitil inhalation powder - 160 microgram[2] Treprostinil,
Treprostinil palmitil		[4] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine ,
Treprostinil palmitil 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
723Treprostinil palmitil inhalation powder - 320 microgram[2] Treprostinil,
Treprostinil palmitil		[4] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine ,
Treprostinil palmitil 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
724Treprostinil palmitil inhalation powder - 80 microgram[2] Treprostinil,
Treprostinil palmitil		[4] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine ,
Treprostinil palmitil 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
725Treprostinil Palmitil Inhalation PowderProduct Code: INS1009Pharmaceutical Form: Inhalation powderINN or Proposed INN: TREPROSTINIL PALMITILCAS Number: 1706528-83-7Current Sponsor code: INS1009Other descriptive name: Treprostinil palmitil inhalation powder - 80 microgramConcentration unit: µg microgram(s)Concentration type: equalConcentration number: 80-Pharmaceutical form of the placebo: Inhalation powderRoute of administration of the placebo: Inhalation useProduct Name: Treprostinil Palmitil Inhalation PowderProduct Code: INS1009Pharmaceutical Form: Inhalation powderINN or Proposed INN: TREPROSTINIL PALMITILCAS Number: 1706528-83-7Current Sponsor code: INS1009Other descriptive name: Treprostinil palmitil inhalation powder - 160 microgramConcentration unit: µg microgram(s)Concentration type: equalConcentration number: 160-Pharmaceutical form of the placebo: Inhalation powderRoute of administration of the placebo: Inhalation useProduct Name: Treprostinil Palmitil Inhalation PowderProduct Code: INS1009Pharmaceutical Form: Inhalation powderINN or Proposed INN: TREPROSTINIL PALMITILCAS Number: 1706528-83-7Current Sponsor code: INS1009Other descriptive name: Treprostinil palmitil inhalation powder - 320 microgramConcentration unit: µg microgram(s)Concentration type: equalConcentration number: 320-Pharmaceutical form of the placebo: Inhalation powderRoute of administration of the placebo: Inhalation use[2] Treprostinil,
Treprostinil palmitil		[4] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine ,
Treprostinil palmitil 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
726TREPROSTINIL SODIUM[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[3] 51, 86, 88 💬
727Treprostinil Sodium Solution for Inhalation[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
728TREPROSTINIL SODIUM, UT-15[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
729Treprostinil, UT-15, LRX-15, 15AU81, BW A15AU, U-62, 840[1] Treprostinil[3] Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
730Trimetazidine[1] Trimetazidine[2] Trimetazidine hydrochloride ,
Trimetazidine 💬 		--[3] 2, 58, 86 💬
731Triple-combination therapy----[1] 86 💬
732Trisuva(r)----[1] 86 💬
733TRK-100STP----[1] 86 💬
734Tyrosine[1] Tyrosine[1] Tyrosine 💬 --[4] 6, 75, 86, 111 💬
735Tyvaso Inhalation Solution----[1] 86 💬
736Ubenimex[1] Ubenimex[1] Ubenimex 💬 [1] ANPEP 💬 [4] Glutathione metabolism, Hematopoietic cell lineage, Phagocytosis, Renin-angiotensin system 💬[1] 86 💬
737Udenafil[1] Udenafil[1] Udenafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 86, 210 💬
738UK 092480----[1] 86 💬
739UK-92,480----[1] 86 💬
740UK-92,480-10----[1] 86 💬
741ULARITIDE[1] Ularitide---[1] 86 💬
742Uptravi----[3] 84, 86, 88 💬
743Uptravi® Film Coated Tablets----[1] 86 💬
744Urodilatin----[1] 86 💬
745Usual Care----[1] 86 💬
746UT-15C----[1] 86 💬
747UT-15C (treprostinil diethanolamine)[2] Diethanolamine,
Treprostinil		[4] Diethanolamine ,
Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
748UT-15C 0.25 mg----[1] 86 💬
749UT-15C 1 mg----[1] 86 💬
750UT-15C 5 mg----[1] 86 💬
751UT-15C LP----[1] 86 💬
752UT-15C SR----[2] 51, 86 💬
753UT-15C SR (treprostinil diethanolamine)[2] Diethanolamine,
Treprostinil		[4] Diethanolamine ,
Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
754UT-15C-SR----[2] 51, 86 💬
755Valsartan[1] Valsartan[1] Valsartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[11] 28, 57, 58, 66, 75, 86, 210, 218, 222, 223, 224 💬
756Valsartan 40 mg[1] Valsartan[1] Valsartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
757Vardenafil[1] Vardenafil[2] Vardenafil ,
Vardenafil hydrochloride 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[3] 13, 86, 299 💬
758Vasodilator-based PAH therapy----[1] 86 💬
759Vasomera[1] Vasomera---[1] 86 💬
760Vasomera (PB1046) Injection[1] Vasomera---[1] 86 💬
761Ventavis----[1] 86 💬
762Ventavis (Iloprost, BAYQ6256)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
763Ventavis 10----[1] 86 💬
764Ventavis(Iloprost)[1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
765Vericiguat[1] Vericiguat[1] Vericiguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 58, 86 💬
766VI-0106----[1] 86 💬
767VIAGRA----[3] 86, 96, 225 💬
768VIP----[3] 49, 51, 86 💬
769Volibris----[4] 51, 85, 86, 88 💬
770VOLIBRIS 10 mg comprimidos recubiertos con película----[1] 86 💬
771VOLIBRIS 5 mg comprimidos recubiertos con película----[1] 86 💬
772VOLIBRIS® (ambrisentan)[1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
773VOLIBRIS™ tablets----[1] 86 💬
774Warfarin[1] Warfarin[3] Warfarin sodium ,
Warfarin potassium ,
Warfarin 💬 		[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
775Water[1] Water[1] Water 💬 --[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬
776Whole Blood[1] Whole Blood[1] Blood, whole 💬 --[9] 44, 45, 50, 65, 86, 177, 226, 283, 299 💬
777ZAMICASTAT[1] Zamicastat---[1] 86 💬
778ZMA001 (BC-NKA-20008)----[1] 86 💬