Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen 💬[1] Acetaminophen[2] Acetaminophen; PARACETAMOL[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
2 Air, medical 💬[1] Medical air[1] Medical air--[3] 85, 86, 193 💬
3 Albuterol 💬[1] Albuterol[2] Albuterol; Salbutamol[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
4 Albuterol sulfate 💬[1] Albuterol[2] Albuterol; Salbutamol[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
5 Ambrisentan 💬[1] Ambrisentan[1] Ambrisentan[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 51, 66, 84, 85, 86, 88, 210, 211, 218, 222 💬
6 Ammonia solution, strong 💬[1] Ammonia[1] Ammonia--[6] 6, 17, 86, 88, 251, 296 💬
7 Anakinra 💬[1] Anakinra[1] ANAKINRA[2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
8 Anastrozole 💬[1] Anastrozole[1] Anastrozole[1] CYP19A1 💬 [2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193 💬
9 Apabetalone 💬[1] Apabetalone[1] Apabetalone--[1] 86 💬
10 Artesunate 💬[1] Artesunate[1] Artesunate--[4] 18, 66, 86, 96 💬
11 Aviptadil 💬[1] Aviptadil[1] Aviptadil--[4] 49, 51, 84, 86 💬
12 Bardoxolone 💬[1] Bardoxolone[1] Bardoxolone--[7] 66, 67, 84, 85, 86, 218, 222 💬
13 Bardoxolone methyl 💬[1] Bardoxolone methyl[1] Bardoxolone Methyl--[7] 66, 67, 84, 85, 86, 218, 222 💬
14 Benzbromarone 💬[1] Benzbromarone[1] BENZBROMARONE--[1] 86 💬
15 Beraprost 💬[1] Beraprost[2] Beraprost; Beraprost Sodium[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
16 Beraprost sodium 💬[1] Beraprost[2] Beraprost; Beraprost Sodium[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
17 Bevacizumab 💬[1] Bevacizumab[1] Bevacizumab[1] VEGFA 💬 [24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
18 Bisoprolol 💬[1] Bisoprolol[2] Bisoprolol; Bisoprolol Fumarate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 57, 58, 67, 86, 113 💬
19 Bisoprolol fumarate 💬[1] Bisoprolol[2] Bisoprolol; Bisoprolol Fumarate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 57, 58, 67, 86, 113 💬
20 Blood, whole 💬[1] Whole Blood[1] Whole Blood--[9] 44, 45, 50, 65, 86, 177, 226, 283, 299 💬
21 Bosentan 💬[1] Bosentan[2] Bosentan; Bosentan monohydrate[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
22 Bosentan 💬[1] Bosentan[2] Bosentan; BOSENTAN MONOHYDRATE[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
23 Calcifediol 💬[1] Calcifediol[1] CALCIFEDIOL[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 86, 113 💬
24 Capsaicin 💬[1] Capsaicin[1] Capsaicin[1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226 💬
25 Captopril 💬[1] Captopril[1] Captopril[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[3] 17, 57, 86 💬
26 Carbon monoxide 💬[1] Carbon monoxide[1] Carbon monoxide--[3] 85, 86, 298 💬
27 Carvedilol 💬[1] Carvedilol[1] Carvedilol[5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		[15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 46, 57, 58, 86, 113, 210 💬
28 Carvedilol phosphate 💬[1] Carvedilol[1] CARVEDILOL[5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		[15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 46, 57, 58, 86, 113, 210 💬
29 Cetuximab 💬[1] Cetuximab[1] Cetuximab[1] EGFR 💬 [49] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬[5] 34, 51, 86, 89, 331 💬
30 Chenodiol 💬[1] Chenodeoxycholic acid[2] Chenodeoxycholic acid; Chenodiol[1] NR1H4 💬 [1] Bile secretion 💬[5] 20, 86, 96, 234, 263 💬
31 Chlorhexidine 💬[1] Chlorhexidine[2] Chlorhexidine; Chlorhexidine Gluconate--[2] 86, 299 💬
32 Chlorhexidine acetate 💬[1] Chlorhexidine[2] Chlorhexidine; Chlorhexidine Gluconate--[2] 86, 299 💬
33 Chlorhexidine gluconate 💬[1] Chlorhexidine[2] Chlorhexidine; Chlorhexidine Gluconate--[2] 86, 299 💬
34 Chlorhexidine hydrochloride 💬[1] Chlorhexidine[2] Chlorhexidine; Chlorhexidine Gluconate--[2] 86, 299 💬
35 Cicletanine 💬[1] Cicletanine[2] Cicletanine; Cicletanine hydrochloride--[1] 86 💬
36 Cicletanine hydrochloride 💬[1] Cicletanine[2] Cicletanine; Cicletanine hydrochloride--[1] 86 💬
37 Citrulline malate 💬[1] Citrulline[2] Citrulline; L-Citrulline--[3] 21, 86, 113 💬
38 Clopidogrel 💬[1] Clopidogrel[1] CLOPIDOGREL[1] P2RY12 💬 [3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬[7] 40, 49, 51, 62, 71, 86, 222 💬
39 Clopidogrel besilate 💬[1] Clopidogrel[1] Clopidogrel[1] P2RY12 💬 [3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬[7] 40, 49, 51, 62, 71, 86, 222 💬
40 Clopidogrel bisulfate 💬[1] Clopidogrel[1] Clopidogrel[1] P2RY12 💬 [3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬[7] 40, 49, 51, 62, 71, 86, 222 💬
41 Clopidogrel hydrochloride 💬[1] Clopidogrel[1] CLOPIDOGREL[1] P2RY12 💬 [3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬[7] 40, 49, 51, 62, 71, 86, 222 💬
42 Conivaptan 💬[1] Conivaptan[1] Conivaptan[2] AVPR1A,
AVPR2 💬 		[6] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 86 💬
43 Conivaptan hydrochloride 💬[1] Conivaptan[1] Conivaptan[2] AVPR1A,
AVPR2 💬 		[6] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 86 💬
44 Dapagliflozin 💬[1] Dapagliflozin[1] Dapagliflozin--[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
45 Diethanolamine 💬[1] Diethanolamine[1] Diethanolamine--[2] 51, 86 💬
46 Diltiazem 💬[1] Diltiazem[2] Diltiazem; Diltiazem Hydrochloride[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 58, 86, 88 💬
47 Diltiazem hydrochloride 💬[1] Diltiazem[2] Diltiazem; Diltiazem Hydrochloride[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 58, 86, 88 💬
48 Diltiazem malate 💬[1] Diltiazem[2] Diltiazem; Diltiazem Hydrochloride[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 58, 86, 88 💬
49 Dimethyl fumarate 💬[1] Dimethyl fumarate[1] Dimethyl fumarate[1] KEAP1 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 20, 51, 86, 296 💬
50 Diphenhydramine 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine Hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
51 Diphenhydramine citrate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
52 Diphenhydramine hydrochloride 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
53 Diphenhydramine salicylate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
54 Dobutamine 💬[1] Dobutamine[2] Dobutamin; Dobutamine[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 28, 57, 58, 86, 215 💬
55 Dobutamine hydrochloride 💬[1] Dobutamine[2] Dobutamin; Dobutamine[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 28, 57, 58, 86, 215 💬
56 Dobutamine tartrate 💬[1] Dobutamine[2] Dobutamin; Dobutamine[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 28, 57, 58, 86, 215 💬
57 Empagliflozin 💬[1] Empagliflozin[1] Empagliflozin--[17] 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
58 Epoprostenol 💬[1] Epoprostenol[3] EPOPROSTENOL; EPOPROSTENOL SODIUM; Prostacyclin[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
59 Epoprostenol sodium 💬[1] Epoprostenol[3] EPOPROSTENOL; EPOPROSTENOL SODIUM; Prostacyclin[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
60 Esomeprazole 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
61 Esomeprazole magnesium 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
62 Esomeprazole magnesium dihydrate 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
63 Esomeprazole sodium 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
64 Esomeprazole strontium 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
65 Esuberaprost 💬[1] Esuberaprost[1] Esuberaprost[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
66 Esuberaprost sodium 💬[1] Esuberaprost[1] Esuberaprost[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
67 Famotidine 💬[1] Famotidine[1] Famotidine[1] HRH2 💬 [4] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[7] 6, 46, 86, 98, 107, 145, 300 💬
68 Ferric carboxymaltose 💬[1] Ferric carboxymaltose[1] FERRIC CARBOXYMALTOSE--[4] 86, 96, 97, 299 💬
69 Fluoxetine 💬[1] Fluoxetine[3] FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 13, 17, 86 💬
70 Fluoxetine hydrochloride 💬[1] Fluoxetine[3] FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 13, 17, 86 💬
71 Fulvestrant 💬[1] Fulvestrant[1] Fulvestrant[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 86 💬
72 Furosemide 💬[1] Furosemide[1] Furosemide[1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[5] 6, 57, 77, 86, 222 💬
73 Glucose 💬[1] D-glucose[1] D-glucose--[3] 49, 86, 88 💬
74 Glycine 💬[1] Glycine[1] Glycine--[7] 35, 60, 86, 226, 247, 299, 340 💬
75 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
76 Ifetroban 💬[1] Ifetroban[2] Ifetroban; Ifetroban Sodium[1] TBXA2R 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[4] 51, 85, 86, 113 💬
77 Ifetroban sodium 💬[1] Ifetroban[2] Ifetroban; Ifetroban Sodium[1] TBXA2R 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[4] 51, 85, 86, 113 💬
78 Iloprost 💬[1] Iloprost[1] Iloprost[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[4] 51, 84, 85, 86 💬
79 Iloprost tromethamine 💬[1] Iloprost[1] Iloprost[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[4] 51, 84, 85, 86 💬
80 Imatinib 💬[1] Imatinib[2] Imatinib; Imatinib mesylate[3] ABL1,
KIT,
PDGFRA 💬 		[34] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
81 Imatinib mesylate 💬[1] Imatinib[2] Imatinib; Imatinib mesylate[3] ABL1,
KIT,
PDGFRA 💬 		[34] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
82 L-Citrulline 💬[1] Citrulline[2] Citrulline; L-Citrulline--[3] 21, 86, 113 💬
83 Lidocaine 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
84 Lidocaine hydrochloride 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
85 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
86 Lisuride 💬[1] Lisuride[1] Lisuride[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86 💬
87 Macitentan 💬[1] Macitentan[1] MACITENTAN[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 51, 85, 86, 88, 210 💬
88 Melatonin 💬[1] Melatonin[1] Melatonin[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
89 Metformin 💬[1] Metformin[4] Metformin; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
90 Metformin hydrochloride 💬[1] Metformin[4] METFORMIN; Metformin hydrochloride; METFORMINA; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
91 Methylprednisolone 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
92 Methylprednisolone acetate 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
93 Morphine 💬[1] Morphine[3] Morphine; Morphine hydrochloride; MORPHINE SULFATE[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
94 Morphine hydrochloride hydrate 💬[1] Morphine[3] Morphine; Morphine hydrochloride; MORPHINE SULFATE[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
95 Morphine sulfate 💬[1] Morphine[3] Morphine; Morphine hydrochloride; Morphine Sulfate[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
96 Morphine tartrate 💬[1] Morphine[3] Morphine; Morphine hydrochloride; Morphine Sulfate[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
97 Moxifloxacin 💬[1] Moxifloxacin[2] Moxifloxacin; Moxifloxacin Hydrochloride--[10] 2, 6, 46, 49, 85, 86, 113, 226, 240, 299 💬
98 Moxifloxacin hydrochloride 💬[1] Moxifloxacin[2] Moxifloxacin; Moxifloxacin Hydrochloride--[10] 2, 6, 46, 49, 85, 86, 113, 226, 240, 299 💬
99 Moxifloxacin hydrochloride monohydrate 💬[1] Moxifloxacin[2] Moxifloxacin; Moxifloxacin hydrochloride--[10] 2, 6, 46, 49, 85, 86, 113, 226, 240, 299 💬
100 Nicardipine 💬[1] Nicardipine[1] Nicardipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 70, 86 💬
101 Nicardipine hydrochloride 💬[1] Nicardipine[1] Nicardipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 70, 86 💬
102 Nilotinib 💬[1] Nilotinib[2] Nilotinib; NILOTINIB HYDROCHLORIDE MONOHYDRATE[4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬 		[35] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86 💬
103 Nitric oxide 💬[1] Nitric Oxide[1] NITRIC OXIDE--[12] 46, 51, 85, 86, 88, 97, 98, 210, 251, 294, 299, 340 💬
104 Nitroglycerin 💬[1] Nitroglycerin[1] Nitroglycerin--[2] 51, 86 💬
105 Olaparib 💬[1] Olaparib[1] Olaparib[2] PARP1,
PARP2 💬 		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285 💬
106 Oxygen 💬[1] Oxygen[1] OXYGEN--[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
107 Pioglitazone 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
108 Pioglitazone hydrochloride 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
109 Prednisone 💬[1] Prednisone[2] Prednisona; PREDNISONE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
110 Ralinepag 💬[1] Ralinepag[1] RALINEPAG[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
111 Ranolazine 💬[1] Ranolazine[1] Ranolazine--[8] 2, 57, 58, 86, 96, 97, 113, 114 💬
112 Ranolazine hydrochloride 💬[1] Ranolazine[1] Ranolazine--[8] 2, 57, 58, 86, 96, 97, 113, 114 💬
113 Rifampicin sodium 💬[1] Rifampin[2] Rifampicin; Rifampin--[5] 6, 13, 84, 86, 299 💬
114 Rifampin 💬[1] Rifampin[2] RIFAMPICIN; Rifampin--[5] 6, 13, 84, 86, 299 💬
115 Riociguat 💬[1] Riociguat[1] RIOCIGUAT[3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299 💬
116 Ritonavir 💬[1] Ritonavir[1] Ritonavir--[3] 2, 86, 265 💬
117 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
118 Rodatristat 💬[1] Rodatristat[1] Rodatristat[1] TPH1 💬 [3] Folate biosynthesis, Serotonergic synapse, Tryptophan metabolism 💬[1] 86 💬
119 Rodatristat ethyl 💬[1] Rodatristat ethyl[1] Rodatristat ethyl[1] TPH1 💬 [3] Folate biosynthesis, Serotonergic synapse, Tryptophan metabolism 💬[1] 86 💬
120 Sapropterin 💬[1] Sapropterin[4] 6R-BH4; SAPROPTERIN; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin--[3] 86, 124, 240 💬
121 Sapropterin dihydrochloride 💬[1] Sapropterin[4] 6R-BH4; Sapropterin; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin--[3] 86, 124, 240 💬
122 Saquinavir 💬[1] Saquinavir[1] Saquinavir--[4] 86, 222, 223, 265 💬
123 Saquinavir mesylate 💬[1] Saquinavir[1] Saquinavir--[4] 86, 222, 223, 265 💬
124 Satralizumab 💬[1] Satralizumab[1] SATRALIZUMAB[1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 11, 13, 86, 113 💬
125 Selexipag 💬[1] Selexipag[1] SELEXIPAG[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 47, 51, 70, 84, 86, 88 💬
126 Selonsertib 💬[1] Selonsertib[1] Selonsertib[1] MAP3K5 💬 [19] Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Huntington disease, Lipid and atherosclerosis, MAPK signaling pathway, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Protein processing in endoplasmic reticulum, Sphingolipid signaling pathway, Spinocerebellar ataxia, TNF signaling pathway, Thermogenesis, Tight junction 💬[1] 86 💬
127 Seralutinib 💬[1] Seralutinib[1] Seralutinib[2] PDGFRA,
PDGFRB 💬 		[22] Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Focal adhesion, Gap junction, Glioma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬[1] 86 💬
128 Serine 💬[1] Serine[2] L-Serine; Serine--[5] 2, 6, 86, 96, 222 💬
129 Sildenafil 💬[1] Sildenafil[3] Sildenafil; Sildenafil citrate; SILDENAFILO[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
130 Sildenafil citrate 💬[1] Sildenafil[3] Sildenafil; SILDENAFIL CITRATE; SILDENAFILO[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
131 Simvastatin 💬[1] Simvastatin[2] Simvastatin; Simvastatine[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
132 Sirolimus 💬[1] Sirolimus[2] Rapamycin; Sirolimus[1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
133 Sitaxentan 💬[1] Sitaxentan[3] Sitaxentan; Sitaxentan sodium; Sitaxsentan[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
134 Sitaxentan sodium 💬[1] Sitaxentan[3] Sitaxentan; Sitaxentan sodium; Sitaxsentan[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
135 Sodium nitrite 💬[1] Nitrous acid[1] SODIUM NITRITE--[2] 86, 299 💬
136 Sorafenib 💬[1] Sorafenib[1] Sorafenib[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Cadherin signaling, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 34, 86 💬
137 Sorafenib tosylate 💬[1] Sorafenib[1] Sorafenib[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Cadherin signaling, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 34, 86 💬
138 Sotatercept 💬[1] Sotatercept[1] SOTATERCEPT[1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[2] 86, 284 💬
139 Spironolactone 💬[1] Spironolactone[1] Spironolactone[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
140 Sulfasalazine 💬[1] Sulfasalazine[2] Sulfasalazine; Sulphasalazine--[7] 46, 49, 86, 94, 107, 270, 271 💬
141 Tadalafil 💬[1] Tadalafil[2] Tadalafil; TADALAFILO[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[8] 6, 51, 75, 77, 84, 86, 113, 210 💬
142 Tamoxifen 💬[1] Tamoxifen[2] Tamoxifen; TAMOXIFEN CITRATE[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[6] 2, 65, 86, 113, 227, 299 💬
143 Tamoxifen citrate 💬[1] Tamoxifen[2] TAMOXIFEN; TAMOXIFEN CITRATE[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[6] 2, 65, 86, 113, 227, 299 💬
144 Terguride 💬[1] Terguride[1] Terguride[2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 51, 86 💬
145 Threonine 💬[1] Threonine[1] Threonine--[3] 86, 96, 97 💬
146 Thrombin 💬[1] Thrombin[1] Thrombin--[3] 86, 88, 97 💬
147 Tocilizumab 💬[1] Tocilizumab[2] BAT1806; Tocilizumab[1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
148 Tolvaptan 💬[1] Tolvaptan[1] TOLVAPTAN[1] AVPR2 💬 [4] Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[5] 67, 72, 86, 222, 225 💬
149 Treprostinil 💬[1] Treprostinil[3] Treprostinil; Treprostinil Diolamine; TREPROSTINIL SODIUM[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210 💬
150 Treprostinil diolamine 💬[1] Treprostinil[3] Treprostinil; Treprostinil Diolamine; TREPROSTINIL SODIUM[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210 💬
151 Treprostinil monosodium salt 💬[1] Treprostinil[3] Treprostinil; Treprostinil Diolamine; TREPROSTINIL SODIUM[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210 💬
152 Treprostinil palmitil 💬[1] Treprostinil palmitil[1] TREPROSTINIL PALMITIL[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
153 Trimetazidine 💬[1] Trimetazidine[2] Trimetazidine; Trimetazidine dihydrochloride--[3] 2, 58, 86 💬
154 Trimetazidine hydrochloride 💬[1] Trimetazidine[2] Trimetazidine; Trimetazidine Dihydrochloride--[3] 2, 58, 86 💬
155 Tyrosine 💬[1] Tyrosine[4] Alanine; L-tyrosine; Propanoic acid; Tyrosine--[4] 6, 75, 86, 111 💬
156 Ubenimex 💬[1] Ubenimex[1] Ubenimex[1] ANPEP 💬 [4] Glutathione metabolism, Hematopoietic cell lineage, Phagocytosis, Renin-angiotensin system 💬[1] 86 💬
157 Udenafil 💬[1] Udenafil[1] Udenafil[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 86, 210 💬
158 Valsartan 💬[1] Valsartan[1] VALSARTAN[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[11] 28, 57, 58, 66, 75, 86, 210, 218, 222, 223, 224 💬
159 Vardenafil 💬[1] Vardenafil[1] Vardenafil[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[3] 13, 86, 299 💬
160 Vardenafil hydrochloride 💬[1] Vardenafil[1] Vardenafil[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[3] 13, 86, 299 💬
161 Vericiguat 💬[1] Vericiguat[1] Vericiguat[3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 58, 86 💬
162 Warfarin 💬[1] Warfarin[3] Warfarin; Warfarin Potassium; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
163 Warfarin potassium 💬[1] Warfarin[3] Warfarin; Warfarin Potassium; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
164 Warfarin sodium 💬[1] Warfarin[3] Warfarin; Warfarin Potassium; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
165 Water 💬[1] Water[1] Water--[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬