Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Leucine 💬[1] Leucine[2] L-leucine; Leucine--[6] 6, 19, 65, 283, 284, 299 💬
2 Cholesterol 💬[1] Cholesterol[1] Cholesterol--[6] 8, 19, 90, 160, 222, 310 💬
3 Gelatin 💬[1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid--[7] 19, 28, 62, 78, 97, 269, 299 💬
4 Methotrexate 💬[1] Methotrexate[6] Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate[2] DHFR,
DHFR2 💬 		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
5 Angiotensin II 💬[1] Angiotensin II[2] Angiotensin; Angiotensin II[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224 💬
6 Cyclosporine 💬[1] Cyclosporine[10] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
7 Cholecalciferol 💬[1] Cholecalciferol[5] CHOLECALCIFEROL; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
8 Acetylcysteine 💬[1] Acetylcysteine[3] Acetylcysteine; Mucomyst; N-acetylcysteine--[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
9 Amoxicillin 💬[1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
10 Azathioprine 💬[1] Azathioprine[3] Azathioprine; Azatioprina; Imuran--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
11 Busulfan 💬[1] Busulfan[3] Busilvex; Busulfan; BUSULFANO--[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
12 Cyclophosphamide 💬[1] Cyclophosphamide[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
13 Gabapentin 💬[1] Gabapentin[4] Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
14 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284 💬
15 Lisinopril 💬[1] Lisinopril[2] Lisinopril; Zestril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222 💬
16 Melphalan 💬[1] Melphalan[3] ALKERAN; Melphalan; Melphalan Hydrochloride--[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
17 Methylprednisolone 💬[1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
18 Prednisone 💬[1] Prednisone[3] Prednisona; Prednisone; RAYOS[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
19 Pyrimethamine 💬[1] Pyrimethamine[2] Daraprim; Pyrimethamine--[4] 2, 4, 19, 65 💬
20 Thiotepa 💬[1] Thiotepa[1] Thiotepa--[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬
21 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[3] CELLCEPT; Mycophenolate Mofetil; Mycophenolate mofetil TEVA[2] IMPDH1,
IMPDH2 💬 		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
22 Sirolimus 💬[1] Sirolimus[3] RAPAMUNE; Rapamycin; Sirolimus[1] MTOR 💬 [51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
23 Paricalcitol 💬[1] Paricalcitol[1] Paricalcitol[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298 💬
24 Calcium carbonate 💬[1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
25 Iohexol 💬[1] Iohexol[2] Iohexol; OMNIPAQUE--[3] 19, 67, 222 💬
26 Angiotensin II 💬[1] Angiotensin II[2] Angiotensin; Angiotensin II[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224 💬
27 Lysine 💬[1] Lysine[1] Lysine--[4] 13, 97, 228, 299 💬
28 Betadex 💬[1] Betadex[1] Beta-cyclodextrin--[1] 19 💬
29 Adalimumab 💬[1] Adalimumab[7] Adalimumab; AMGEVITA; Cyltezo; Hulio; HUMIRA; Hyrimoz; Imraldi[1] TNF 💬 [67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
30 Agalsidase alfa 💬[1] Agalsidase alfa[5] AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL[1] GLA 💬 [6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19 💬
31 Alemtuzumab 💬[1] Alemtuzumab[4] ALEMTUZUMAB; Campath; Lemtrada; MABCAMPATH[1] CD52 💬 [1] 💬[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
32 Alglucerase 💬[1] Alglucerase[1] Ceredase[1] GBA1 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
33 Rituximab 💬[1] Rituximab[6] MabThera; Rituxan; Rituximab; Rixathon; Ruxience; Truxima[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
34 Imiglucerase 💬[1] Imiglucerase[3] CEREZYME; IMIGLUCERASA; IMIGLUCERASE[1] GBA1 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
35 Abatacept 💬[1] Abatacept[2] Abatacept; ORENCIA[2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
36 Agalsidase beta 💬[1] Agalsidase beta[2] AGALSIDASE BETA; FABRAZYME[1] GLA 💬 [6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19 💬
37 Lenograstim 💬[1] Lenograstim[2] G-CSF; LENOGRASTIM[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65 💬
38 Lactase 💬[1] Tilactase[1] Beta-Galactosidase--[1] 19 💬
39 Clofarabine 💬[1] Clofarabine[1] Clofarabine[3] POLA1,
POLA2,
RRM1 💬 		[7] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 234, 326 💬
40 Cysteamine 💬[1] Cysteamine[8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; CYSTEAMINE; Mercaptamina; Mercaptamine; PROCYSBI--[4] 8, 19, 21, 299 💬
41 Quinapril 💬[1] Quinapril[1] Accuretic[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 19 💬
42 Idursulfase 💬[1] Idursulfase[4] Elaprase; Iduronate 2-sulfatase; IDURSULFASA; IDURSULFASE[1] IDS 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19 💬
43 Laronidase 💬[1] Laronidase[2] Aldurazyme; LARONIDASE[1] IDUA 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[2] 19, 256 💬
44 Miglustat 💬[1] Miglustat[2] MIGLUSTAT; ZAVESCA[1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism 💬[3] 19, 256, 299 💬
45 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic[2] IMPDH1,
IMPDH2 💬 		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
46 Galsulfase 💬[1] Galsulfase[2] GALSULFASE; Naglazyme[1] ARSB 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19 💬
47 Donkey glue 💬[1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid--[7] 19, 28, 62, 78, 97, 269, 299 💬
48 Alendronic acid 💬[1] Alendronic acid[3] Alendronate; Alendronate sodium; ALENDRONIC ACID[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299 💬
49 Gamolenic acid 💬[1] Gamolenic acid[2] Gamma-Linolenic acid; Linolenic acid--[1] 46 💬
50 Treosulfan 💬[1] Treosulfan[2] OVASTAT; Treosulfan--[6] 13, 19, 62, 65, 283, 286 💬
51 Ambroxol 💬[1] Ambroxol[1] Ambroxol--[2] 6, 19 💬
52 Amoxicillin 💬[1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
53 Betaine 💬[1] Betaine[2] Betaine; Cystadane--[3] 19, 201, 337 💬
54 Cyclophosphamide 💬[1] Cyclophosphamide[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
55 Enalapril 💬[1] Enalapril[2] ENALAPRIL; Enalapril Maleate[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222 💬
56 Fludarabine 💬[1] Fludarabine[4] FLUDARA; Fludarabina; Fludarabine; Fludarabine phosphate[1] RRM1 💬 [6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
57 Folinic acid 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[4] 19, 46, 107, 320 💬
58 Folinic acid calcium salt pentahydrate 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[4] 19, 46, 107, 320 💬
59 Levothyroxine 💬[1] Levothyroxine[2] Levothyroxine; Thyroxine[2] THRA,
THRB 💬 		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 19, 49, 78, 80 💬
60 Lisinopril 💬[1] Lisinopril[2] Lisinopril; Zestril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222 💬
61 Losartan 💬[1] Losartan[3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
62 Warfarin 💬[1] Warfarin[2] Warfarin; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
63 Dapagliflozin 💬[1] Dapagliflozin[2] Dapagliflozin; Forxiga[1] SLC5A2 💬 [1] 💬[7] 19, 49, 66, 67, 86, 88, 222 💬
64 Plerixafor 💬[1] Plerixafor[2] Mozobil; Plerixafor[1] CXCR4 💬 [14] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[5] 19, 20, 65, 285, 299 💬
65 Velaglucerase alfa 💬[1] Velaglucerase alfa[3] GA-GCB; VELAGLUCERASE ALFA; VPRIV[1] GBA1 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
66 Ataluren 💬[1] Ataluren[2] ATALUREN; Translarna--[6] 19, 113, 140, 246, 299, 329 💬
67 Afegostat 💬[1] Afegostat[1] Afegostat--[1] 19 💬
68 Taliglucerase alfa 💬[1] Taliglucerase alfa[3] Elelyso; PrGCD; TALIGLUCERASE ALFA[1] GBA1 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
69 Eliglustat 💬[1] Eliglustat[2] Cerdelga; Eliglustat[1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19 💬
70 Elosulfase alfa 💬[1] Elosulfase alfa[3] Elosulfase alfa; Recombinant human N-acetylgalactosamine-6-sulfatase; RhGALNS[1] GALNS 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19 💬
71 Migalastat 💬[1] Migalastat[3] 1-Deoxygalactonojirimycin; Galafold; MIGALASTAT--[1] 19 💬
72 Sofosbuvir 💬[1] Sofosbuvir[1] Sofosbuvir--[1] 19 💬
73 Sebelipase alfa 💬[1] Sebelipase alfa[4] KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa[1] LIPA 💬 [3] Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬[1] 19 💬
74 Ledipasvir 💬[1] Ledipasvir[1] Ledipasvir--[1] 19 💬
75 Calcium carbonate 💬[1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium Carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
76 Cerliponase alfa 💬[1] Cerliponase alfa[2] Brineura; Cerliponase Alfa[1] TPP1 💬 [1] Lysosome 💬[1] 19 💬
77 Olipudase alfa 💬[1] Olipudase alfa[1] OLIPUDASE ALFA[1] SMPD1 💬 [5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19 💬
78 Vestronidase alfa 💬[1] Vestronidase alfa[3] Mepsevii; Recombinant human beta-glucuronidase; Vestronidase alfa[1] GUSB 💬 [8] Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin metabolism 💬[1] 19 💬
79 Velmanase alfa 💬[1] Velmanase alfa[3] LAMAZYM; RhLAMAN; VELMANASE ALFA[1] MAN2B1 💬 [2] Lysosome, Other glycan degradation 💬[1] 19 💬
80 Idursulfase beta 💬[1] Idursulfase beta[3] Hunterase; Iduronate 2-sulfatase; Idursulfase beta[1] IDS 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19 💬
81 Rimiducid 💬[1] Rimiducid[1] Rimiducid[1] CASP9 💬 [35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326 💬
82 Arimoclomol 💬[1] Arimoclomol[1] ARIMOCLOMOL--[3] 2, 15, 19 💬
83 Lucerastat 💬[1] Lucerastat[1] Lucerastat[1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19 💬
84 Venglustat 💬[1] Venglustat[2] GENZ-682452; Venglustat[1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism 💬[3] 6, 19, 67 💬
85 Genistein 💬[1] Genistein[1] GENISTEIN--[2] 19, 299 💬
86 Pegunigalsidase alfa 💬[1] Pegunigalsidase alfa[1] PEGUNIGALSIDASE ALFA--[1] 19 💬
87 Pabinafusp alfa 💬[1] Pabinafusp alfa[1] Pabinafusp alfa[2] IDS,
TFRC 💬 		[8] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Metabolic pathways, Phagosome 💬[1] 19 💬