Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[1] Abatacept[2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Acetaminophen 💬[1] Acetaminophen[2] Acetaminophen; PARACETAMOL[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
3 Acetylcysteine 💬[1] Acetylcysteine[4] Acetylcysteine; N acetyl cysteine; N-acetyl Cysteine; N-acetylcysteine--[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
4 Adalimumab 💬[1] Adalimumab[1] Adalimumab[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
5 Afegostat 💬[1] Afegostat[2] Afegostat; Afegostat tartrate--[1] 19 💬
6 Afegostat tartrate 💬[1] Afegostat[2] Afegostat; Afegostat tartrate--[1] 19 💬
7 Agalsidase alfa 💬[1] Agalsidase alfa[3] AGALSIDASE ALFA; Agalsidase Alpha; Recombinant alpha-galactosidase A[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬[1] 19 💬
8 Agalsidase beta 💬[1] Agalsidase beta[1] AGALSIDASE BETA[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬[1] 19 💬
9 Alemtuzumab 💬[1] Alemtuzumab[1] Alemtuzumab--[21] 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
10 Alendronate sodium 💬[1] Alendronic acid[3] Alendronate; Alendronate sodium; ALENDRONIC ACID[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[5] 19, 46, 223, 274, 299 💬
11 Alendronic acid 💬[1] Alendronic acid[3] Alendronate; Alendronate sodium; ALENDRONIC ACID[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[5] 19, 46, 223, 274, 299 💬
12 Alglucerase 💬[1] Imiglucerase[2] IMIGLUCERASA; IMIGLUCERASE[1] GBA1 💬 [4] Cornified envelope formation, Lysosome biogenesis, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
13 Ambroxol 💬[1] Ambroxol[2] Ambroxol; Ambroxol Hydrochloride--[3] 2, 6, 19 💬
14 Ambroxol hydrochloride 💬[1] Ambroxol[2] Ambroxol; Ambroxol Hydrochloride--[3] 2, 6, 19 💬
15 Anakinra 💬[1] Anakinra[1] Anakinra[2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
16 Arimoclomol 💬[1] Arimoclomol[2] ARIMOCLOMOL; Arimoclomol citrate--[3] 2, 15, 19 💬
17 Arimoclomol citrate 💬[1] Arimoclomol[2] ARIMOCLOMOL; Arimoclomol citrate--[3] 2, 15, 19 💬
18 Ataluren 💬[1] Ataluren[1] ATALUREN--[6] 19, 113, 140, 246, 299, 329 💬
19 Azathioprine 💬[1] Azathioprine[2] Azathioprine; AZATIOPRINA--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
20 Azathioprine sodium 💬[1] Azathioprine[2] Azathioprine; Azatioprina--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
21 Busulfan 💬[1] Busulfan[2] Busulfan; BUSULFANO--[14] 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
22 Calcium carbonate 💬[1] Calcium carbonate[1] Calcium carbonate--[10] 13, 19, 46, 53, 71, 75, 96, 97, 235, 299 💬
23 Calcium carbonate 💬[1] Calcium carbonate[1] Calcium Carbonate--[10] 13, 19, 46, 53, 71, 75, 96, 97, 235, 299 💬
24 Cannabidiol 💬[1] Cannabidiol[1] CANNABIDIOL[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
25 Capsaicin 💬[1] Capsaicin[1] Capsaicin[1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226 💬
26 Cerliponase alfa 💬[1] Cerliponase alfa[2] Cerliponase Alfa; Recombinant human tripeptidyl peptidase-1[1] TPP1 💬 [1] Lysosome biogenesis 💬[1] 19 💬
27 Cetirizine 💬[1] Cetirizine[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 13, 19, 35 💬
28 Cetirizine hydrochloride 💬[1] Cetirizine[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 13, 19, 35 💬
29 Cholecalciferol 💬[1] Cholecalciferol[4] CHOLECALCIFEROL; Colecalciferol; Vitamin D-3; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[10] 13, 19, 34, 46, 49, 96, 97, 222, 298, 299 💬
30 Cholesterol 💬[1] Cholesterol[1] Cholesterol--[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
31 Clofarabine 💬[1] Clofarabine[1] Clofarabine[3] POLA1,
POLA2,
RRM1 💬 		[5] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
32 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; CYCLOPHOSPHAMIDE; CYCLOPHOSPHAMIDE MONOHYDRATE--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
33 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
34 Cyclosporine 💬[1] Cyclosporine[7] CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
35 Cysteamine 💬[1] Cysteamine[6] 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; CYSTEAMINE HYDROCHLORIDE; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
36 Cysteamine bitartrate 💬[1] Cysteamine[6] 2-aminoethanethiol; CYSTEAMINE; Cysteamine Bitartrate; CYSTEAMINE HYDROCHLORIDE; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
37 Cysteamine hydrochloride 💬[1] Cysteamine[6] 2-aminoethanethiol; CYSTEAMINE; Cysteamine Bitartrate; CYSTEAMINE HYDROCHLORIDE; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
38 Cysteine hydrochloride 💬[1] Cysteine[2] Cysteine; Cysteine hydrochloride--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
39 Dapagliflozin 💬[1] Dapagliflozin[1] Dapagliflozin--[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
40 Dexamethasone 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; DEXAMETHASONE; DEXAMETHASONE SODIUM PHOSPHATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
41 Dexamethasone phosphate 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; DEXAMETHASONE; DEXAMETHASONE SODIUM PHOSPHATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
42 Dexamethasone sodium phosphate 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
43 Diphenhydramine 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
44 Diphenhydramine citrate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
45 Diphenhydramine hydrochloride 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
46 Diphenhydramine salicylate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine Hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
47 Eliglustat 💬[1] Eliglustat[2] Eliglustat; ELIGLUSTAT TARTRATE[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[1] 19 💬
48 Eliglustat tartrate 💬[1] Eliglustat[2] Eliglustat; ELIGLUSTAT TARTRATE[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[1] 19 💬
49 Elosulfase alfa 💬[1] Elosulfase alfa[1] Elosulfase alfa[1] GALNS 💬 [2] Glycosaminoglycan degradation, Lysosome biogenesis 💬[1] 19 💬
50 Enalapril 💬[1] Enalapril[2] Enalapril; Enalapril Maleate[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[10] 13, 19, 46, 57, 66, 113, 210, 222, 223, 279 💬
51 Enalapril maleate 💬[1] Enalapril[2] Enalapril; Enalapril Maleate[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[10] 13, 19, 46, 57, 66, 113, 210, 222, 223, 279 💬
52 Fexofenadine 💬[1] Fexofenadine[1] Fexofenadine[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[4] 6, 13, 19, 46 💬
53 Fexofenadine hydrochloride 💬[1] Fexofenadine[1] Fexofenadine[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[4] 6, 13, 19, 46 💬
54 Fludarabine 💬[1] Fludarabine[3] FLUDARABINA; FLudarabine; Fludarabine phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
55 Fludarabine phosphate 💬[1] Fludarabine[3] FLUDARABINA; Fludarabine; FLUDARABINE PHOSPHATE[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
56 Fluorescein 💬[1] Fluorescein[1] Fluorescein--[4] 19, 22, 41, 97 💬
57 Fluorescein sodium 💬[1] Fluorescein[1] Fluorescein--[4] 19, 22, 41, 97 💬
58 Folinic acid 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[3] 13, 19, 46 💬
59 Folinic acid calcium salt pentahydrate 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[3] 13, 19, 46 💬
60 Gabapentin 💬[1] Gabapentin[3] GABAPENTIN; GABAPENTINA; Gabapentine[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[10] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[7] 6, 13, 18, 19, 70, 226, 298 💬
61 Galsulfase 💬[1] Galsulfase[1] GALSULFASE[1] ARSB 💬 [2] Glycosaminoglycan degradation, Lysosome biogenesis 💬[1] 19 💬
62 Genistein 💬[1] Genistein[1] GENISTEIN--[2] 19, 299 💬
63 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
64 Idursulfase 💬[1] Idursulfase[2] IDURSULFASA; IDURSULFASE[1] IDS 💬 [2] Glycosaminoglycan degradation, Lysosome biogenesis 💬[1] 19 💬
65 Idursulfase beta 💬[1] Idursulfase beta[2] Hunterase; Idursulfase beta[1] IDS 💬 [2] Glycosaminoglycan degradation, Lysosome biogenesis 💬[1] 19 💬
66 Imiglucerase 💬[1] Imiglucerase[2] IMIGLUCERASA; IMIGLUCERASE[1] GBA1 💬 [4] Cornified envelope formation, Lysosome biogenesis, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
67 Iohexol 💬[1] Iohexol[1] Iohexol--[2] 19, 67 💬
68 L-Cysteine 💬[1] Cysteine[2] Cysteine; Cysteine hydrochloride--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
69 Laronidase 💬[1] Laronidase[1] Laronidase[1] IDUA 💬 [2] Glycosaminoglycan degradation, Lysosome biogenesis 💬[2] 19, 256 💬
70 Ledipasvir 💬[1] Ledipasvir[1] Ledipasvir--[1] 19 💬
71 Lenograstim 💬[1] Lenograstim[2] G-CSF; Lenograstim[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[8] 2, 13, 16, 18, 19, 57, 65, 97 💬
72 Leucine 💬[1] Leucine[2] L-leucine; Leucine--[13] 5, 6, 7, 18, 19, 65, 96, 97, 127, 280, 283, 284, 299 💬
73 Leucovorin calcium 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[3] 13, 19, 46 💬
74 Lisinopril 💬[1] Lisinopril[1] Lisinopril[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[9] 19, 46, 49, 57, 66, 67, 113, 222, 223 💬
75 Lisinopril 💬[1] Lisinopril[1] Lisinopril[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[9] 19, 46, 49, 57, 66, 67, 113, 222, 223 💬
76 Loratadine 💬[1] Loratadine[1] Loratadine[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 13, 19, 46, 89, 98 💬
77 Losartan 💬[1] Losartan[2] Losartan; Losartan Potassium[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
78 Losartan potassium 💬[1] Losartan[2] Losartan; Losartan Potassium[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
79 Lucerastat 💬[1] Lucerastat[1] Lucerastat[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[1] 19 💬
80 Melphalan 💬[1] Melphalan[2] MELPHALAN; Melphalan Hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
81 Melphalan hydrochloride 💬[1] Melphalan[2] MELPHALAN; Melphalan Hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
82 Methotrexate 💬[1] Methotrexate[5] Methotrexat; Methotrexate; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
83 Methotrexate sodium 💬[1] Methotrexate[5] Methotrexat; Methotrexate; METHOTREXATE SODIUM; Methylaminopterin; Metotrexato[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
84 Methylprednisolone 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
85 Methylprednisolone acetate 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
86 Migalastat 💬[1] Migalastat[2] MIGALASTAT; MIGALASTAT HYDROCHLORIDE--[1] 19 💬
87 Migalastat hydrochloride 💬[1] Migalastat[2] MIGALASTAT; MIGALASTAT HYDROCHLORIDE[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬[1] 19 💬
88 Miglustat 💬[1] Miglustat[2] AT2221; MIGLUSTAT[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[3] 19, 256, 299 💬
89 Montelukast 💬[1] Montelukast[2] MONTELUKAST; MONTELUKAST SODIUM[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[10] 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
90 Montelukast sodium 💬[1] Montelukast[2] Montelukast; MONTELUKAST SODIUM[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[10] 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
91 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
92 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate Mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
93 Nizubaglustat 💬[1] Nizubaglustat[2] AZ-3102; Nizubaglustat[2] GBA2,
UGCG 💬 		[3] Cornified envelope formation, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
94 Olipudase alfa 💬[1] Olipudase alfa[1] OLIPUDASE ALFA[1] SMPD1 💬 [4] Lysosome biogenesis, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19 💬
95 Oxygen 💬[1] Oxygen[1] Oxygen--[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
96 Pabinafusp alfa 💬[1] Pabinafusp alfa[1] Pabinafusp alfa[2] IDS,
TFRC 💬 		[8] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome biogenesis, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬[1] 19 💬
97 Paricalcitol 💬[1] Paricalcitol[1] Paricalcitol[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298 💬
98 Pegunigalsidase alfa 💬[1] Pegunigalsidase alfa[1] PEGUNIGALSIDASE ALFA[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬[1] 19 💬
99 Pentosan polysulfate sodium 💬[1] Pentosan polysulfate[2] Pentosan polysulfate; PENTOSAN POLYSULFATE SODIUM--[3] 19, 26, 226 💬
100 Prednisone 💬[1] Prednisone[2] Prednisona; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
101 Pyrimethamine 💬[1] Pyrimethamine[1] PYRIMETHAMINE--[4] 2, 4, 19, 65 💬
102 Rimiducid 💬[1] Rimiducid[1] Rimiducid[1] CASP9 💬 [34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[7] 19, 49, 60, 65, 284, 285, 326 💬
103 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
104 Rivogenlecleucel 💬[1] Rivogenlecleucel[1] Rivogenlecleucel--[6] 19, 60, 65, 284, 285, 326 💬
105 Sebelipase alfa 💬[1] Sebelipase alfa[3] SBC-102; Sebelipasa Alfa; Sebelipase Alfa[1] LIPA 💬 [4] Cholesterol metabolism, Efferocytosis, Lysosome biogenesis, Steroid biosynthesis 💬[1] 19 💬
106 Sirolimus 💬[1] Sirolimus[2] Rapamycin; SIROLIMUS[1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
107 Sofosbuvir 💬[1] Sofosbuvir[1] Sofosbuvir--[1] 19 💬
108 Taliglucerase alfa 💬[1] Taliglucerase alfa[2] PrGCD; TALIGLUCERASE ALFA[1] GBA1 💬 [4] Cornified envelope formation, Lysosome biogenesis, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
109 Thiotepa 💬[1] Thiotepa[1] Thiotepa--[14] 13, 19, 20, 28, 46, 51, 60, 65, 85, 96, 107, 164, 284, 285 💬
110 Tividenofusp alfa 💬[1] Tividenofusp alfa[1] Tividenofusp alfa[2] IDS,
TFRC 💬 		[8] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome biogenesis, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬[1] 19 💬
111 Tralesinidase alfa 💬[1] Tralesinidase alfa[2] RHNAGLU-IGF2; Tralesinidase alfa[2] IGF2,
NAGLU 💬 		[9] Glycosaminoglycan degradation, Hepatocellular carcinoma, Hormone signaling, Lysosome biogenesis, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Ras signaling pathway 💬[1] 19 💬
112 Treosulfan 💬[1] Treosulfan[1] Treosulfan--[6] 13, 19, 62, 65, 284, 286 💬
113 Tropicamide 💬[1] Tropicamide[1] Tropicamide[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 6, 19 💬
114 Velaglucerase alfa 💬[1] Velaglucerase alfa[2] GA-GCB; VELAGLUCERASE ALFA[1] GBA1 💬 [4] Cornified envelope formation, Lysosome biogenesis, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
115 Velmanase alfa 💬[1] Velmanase alfa[3] LAMAZYM; RhLAMAN; VELMANASE ALFA[1] MAN2B1 💬 [2] Lysosome biogenesis, Other glycan degradation 💬[1] 19 💬
116 Venglustat 💬[1] Venglustat[2] Venglustat; Venglustat malate[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[3] 6, 19, 67 💬
117 Venglustat malate 💬[1] Venglustat[2] Venglustat; Venglustat malate--[3] 6, 19, 67 💬
118 Vestronidase alfa 💬[1] Vestronidase alfa[2] Recombinant human beta-glucuronidase; Vestronidase alfa[1] GUSB 💬 [6] Ascorbate and aldarate metabolism, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome biogenesis, Pentose and glucuronate interconversions, Porphyrin metabolism 💬[1] 19 💬
119 Vitamin E 💬[1] Vitamin E[1] Vitamin E--[12] 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
120 Vosoritide 💬[1] Vosoritide[1] Vosoritide[1] NPR2 💬 [5] Hormone signaling, Oxytocin signaling pathway, Purine metabolism, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 19, 195, 276 💬
121 Warfarin 💬[1] Warfarin[3] Warfarin; Warfarin Potassium; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
122 Warfarin potassium 💬[1] Warfarin[3] Warfarin; Warfarin Potassium; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
123 Warfarin sodium 💬[1] Warfarin[3] Warfarin; Warfarin Potassium; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
124 Water 💬[1] Water[1] Water--[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬