Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[1] Abatacept[2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetaminophen 💬[1] Acetaminophen[2] Acetaminophen; Paracetamol[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[17] 3, 6, 11, 13, 19, 34, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
3 Adalimumab 💬[1] Adalimumab[1] Adalimumab[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[18] 19, 37, 40, 41, 46, 55, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
4 Afegostat 💬[1] Afegostat[1] Afegostat tartrate--[1] 19 💬
5 Afegostat tartrate 💬[1] Afegostat[1] Afegostat tartrate--[1] 19 💬
6 Agalsidase alfa 💬[1] Agalsidase alfa[3] Agalsidase alfa; Agalsidase alpha; Recombinant alpha-galactosidase A[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬[1] 19 💬
7 Agalsidase beta 💬[1] Agalsidase beta[1] Agalsidase beta[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬[1] 19 💬
8 Alemtuzumab 💬[1] Alemtuzumab[1] Alemtuzumab--[18] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
9 Alendronate sodium 💬[1] Alendronic acid[3] Alendronate; Alendronate sodium; Alendronic acid[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299 💬
10 Alendronic acid 💬[1] Alendronic acid[3] Alendronate; Alendronate sodium; Alendronic acid[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299 💬
11 Alglucerase 💬[1] Imiglucerase[2] Imiglucerasa; Imiglucerase[1] GBA 💬 [4] Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
12 Ambroxol 💬[1] Ambroxol[2] Ambroxol; Ambroxol hydrochloride--[3] 2, 6, 19 💬
13 Ambroxol hydrochloride 💬[1] Ambroxol[2] Ambroxol; Ambroxol hydrochloride--[3] 2, 6, 19 💬
14 Amoxicillin 💬[1] Amoxicillin[2] Amoxicilina; Amoxicillin--[5] 46, 63, 96, 97, 299 💬
15 Amoxicillin 💬[1] Amoxicillin[2] Amoxicilina; Amoxicillin--[5] 46, 63, 96, 97, 299 💬
16 Amoxicillin sodium 💬[1] Amoxicillin[2] Amoxicilina; Amoxicillin--[5] 46, 63, 96, 97, 299 💬
17 Anakinra 💬[1] Anakinra[1] Anakinra[2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[19] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 84, 86, 97, 106, 107, 266, 299 💬
18 Arimoclomol 💬[1] Arimoclomol[2] Arimoclomol; Arimoclomol citrate--[3] 2, 15, 19 💬
19 Arimoclomol citrate 💬[1] Arimoclomol[2] Arimoclomol; Arimoclomol citrate--[3] 2, 15, 19 💬
20 Ataluren 💬[1] Ataluren[1] Ataluren--[6] 19, 113, 140, 246, 299, 329 💬
21 Azathioprine 💬[1] Azathioprine[2] Azathioprine; Azatioprina--[22] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
22 Azathioprine sodium 💬[1] Azathioprine[2] Azathioprine; Azatioprina--[22] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
23 Busulfan 💬[1] Busulfan[2] Busulfan; Busulfano--[14] 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
24 Calcium carbonate 💬[1] Calcium carbonate[1] Calcium carbonate--[7] 13, 19, 46, 75, 96, 235, 299 💬
25 Calcium carbonate 💬[1] Calcium carbonate[1] Calcium carbonate--[7] 13, 19, 46, 75, 96, 235, 299 💬
26 Cannabidiol 💬[1] Cannabidiol[1] Cannabidiol[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 19, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 271 💬
27 Cannabis 💬[1] Medical Cannabis[2] Cannabis; Medical cannabis--[6] 6, 13, 46, 90, 96, 97 💬
28 Cerliponase alfa 💬[1] Cerliponase alfa[2] Cerliponase alfa; Recombinant human tripeptidyl peptidase-1[1] TPP1 💬 [1] Lysosome 💬[1] 19 💬
29 Cetirizine 💬[1] Cetirizine[3] Cetirizina; Cetirizine; Cetirizine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 13, 19, 35, 300, 309 💬
30 Cetirizine hydrochloride 💬[1] Cetirizine[3] Cetirizina; Cetirizine; Cetirizine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 13, 19, 35, 300, 309 💬
31 Cholecalciferol 💬[1] Cholecalciferol[4] Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[15] 6, 13, 19, 20, 34, 46, 49, 51, 53, 65, 96, 97, 228, 298, 299 💬
32 Cholesterol 💬[1] Cholesterol[1] Cholesterol--[5] 19, 90, 160, 222, 310 💬
33 Clofarabine 💬[1] Clofarabine[1] Clofarabine[3] POLA1,
POLA2,
RRM1 💬 		[5] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 96, 234 💬
34 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--[46] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
35 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--[46] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
36 Cyclosporine 💬[1] Cyclosporine[6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
37 Cysteamine 💬[1] Cysteamine[6] 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
38 Cysteamine bitartrate 💬[1] Cysteamine[6] 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
39 Cysteamine hydrochloride 💬[1] Cysteamine[6] 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
40 Dapagliflozin 💬[1] Dapagliflozin[1] Dapagliflozin--[10] 6, 28, 49, 66, 67, 86, 88, 215, 218, 222 💬
41 Dexamethasone 💬[1] Dexamethasone[2] Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[23] 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
42 Dexamethasone phosphate 💬[1] Dexamethasone[2] Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[23] 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
43 Dexamethasone sodium phosphate 💬[1] Dexamethasone[2] Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[23] 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
44 Diphenhydramine 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
45 Diphenhydramine citrate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
46 Diphenhydramine hydrochloride 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
47 Diphenhydramine salicylate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
48 Donkey glue 💬[1] Gelatin[2] Gelatin; Gelatine--[5] 19, 47, 62, 70, 296 💬
49 Edotreotide gallium Ga-68 💬[1] Dotatate gallium Ga-68[1] 68GA-dotatate[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75 💬
50 Eliglustat 💬[1] Eliglustat[2] Eliglustat; Eliglustat tartrate[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[1] 19 💬
51 Eliglustat tartrate 💬[1] Eliglustat[2] Eliglustat; Eliglustat tartrate[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[1] 19 💬
52 Elosulfase alfa 💬[1] Elosulfase alfa[2] Elosulfase alfa; Rhgalns[1] GALNS 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[1] 19 💬
53 Enalapril 💬[1] Enalapril[2] Enalapril; Enalapril maleate[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 13, 46, 66, 113, 210, 222, 279 💬
54 Enalapril maleate 💬[1] Enalapril[2] Enalapril; Enalapril maleate[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 13, 46, 66, 113, 210, 222, 279 💬
55 Fexofenadine 💬[1] Fexofenadine[1] Fexofenadine[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[4] 6, 13, 19, 46 💬
56 Fexofenadine hydrochloride 💬[1] Fexofenadine[1] Fexofenadine[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[4] 6, 13, 19, 46 💬
57 Fludarabine 💬[1] Fludarabine[2] Fludarabine; Fludarabine phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[25] 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
58 Fludarabine phosphate 💬[1] Fludarabine[2] Fludarabine; Fludarabine phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[25] 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
59 Fluorescein 💬[1] Fluorescein[1] Fluorescein--[2] 22, 97 💬
60 Fluorescein sodium 💬[1] Fluorescein[1] Fluorescein--[2] 22, 97 💬
61 Folinic acid 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[3] 19, 46, 320 💬
62 Folinic acid calcium salt pentahydrate 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[3] 19, 46, 320 💬
63 Gabapentin 💬[1] Gabapentin[2] Gabapentin; Gabapentine[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[10] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[4] 6, 13, 19, 70 💬
64 Galsulfase 💬[1] Galsulfase[1] Galsulfase[1] ARSB 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[1] 19 💬
65 Gamolenic acid 💬[1] Gamolenic acid[1] Gamma-linolenic acid--[1] 46 💬
66 Gelatin 💬[1] Gelatin[2] Gelatin; Gelatine--[5] 19, 47, 62, 70, 296 💬
67 Genistein 💬[1] Genistein[1] Genistein--[1] 299 💬
68 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
69 Idursulfase 💬[1] Idursulfase[2] Idursulfasa; Idursulfase[1] IDS 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[1] 19 💬
70 Idursulfase beta 💬[1] Idursulfase beta[2] Hunterase; Idursulfase beta[1] IDS 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[1] 19 💬
71 Imiglucerase 💬[1] Imiglucerase[2] Imiglucerasa; Imiglucerase[1] GBA 💬 [4] Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
72 Iohexol 💬[1] Iohexol[1] Iohexol--[2] 19, 67 💬
73 Laronidase 💬[1] Laronidase[1] Laronidase[1] IDUA 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[2] 19, 256 💬
74 Ledipasvir 💬[1] Ledipasvir[0] ---
75 Lenograstim 💬[1] Lenograstim[2] G-CSF; Lenograstim[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[8] 2, 13, 16, 18, 19, 57, 65, 97 💬
76 Lesinidase alfa 💬[1] Lesinidase alfa[1] SBC-103[1] NAGLU 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[1] 19 💬
77 Leucovorin calcium 💬[1] Leucovorin[2] Folinic acid; Leucovorin--[3] 19, 46, 320 💬
78 Lisinopril 💬[1] Lisinopril[1] Lisinopril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[5] 19, 46, 66, 67, 113 💬
79 Lisinopril 💬[1] Lisinopril[1] Lisinopril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[5] 19, 46, 66, 67, 113 💬
80 Loratadine 💬[1] Loratadine[1] Loratadine[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 13, 19, 46, 89, 98 💬
81 Losartan 💬[1] Losartan[2] Losartan; Losartan potassium[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
82 Losartan potassium 💬[1] Losartan[2] Losartan; Losartan potassium[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
83 Lucerastat 💬[1] Lucerastat[1] Lucerastat[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[1] 19 💬
84 Lysine 💬[1] Lysine[1] Lysine--[1] 228 💬
85 Lysine acetate 💬[1] Lysine[1] Lysine--[1] 228 💬
86 Lysine hydrochloride 💬[1] Lysine[1] Lysine--[1] 228 💬
87 Lysine hydrochloride 💬[1] Lysine[1] Lysine--[1] 228 💬
88 Melphalan 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
89 Melphalan hydrochloride 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
90 Methotrexate 💬[1] Methotrexate[5] Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
91 Methotrexate sodium 💬[1] Methotrexate[5] Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
92 Methylprednisolone 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[45] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
93 Methylprednisolone acetate 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[45] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
94 Migalastat 💬[1] Migalastat[2] Migalastat; Migalastat hydrochloride--[1] 19 💬
95 Migalastat hydrochloride 💬[1] Migalastat[2] Migalastat; Migalastat hydrochloride[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬[1] 19 💬
96 Miglustat 💬[1] Miglustat[2] AT2221; Miglustat[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[3] 19, 256, 299 💬
97 Montelukast 💬[1] Montelukast[2] Montelukast; Montelukast sodium[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[9] 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
98 Montelukast sodium 💬[1] Montelukast[2] Montelukast; Montelukast sodium[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[9] 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
99 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
100 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
101 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
102 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
103 Olipudase alfa 💬[1] Olipudase alfa[1] Olipudase alfa[1] SMPD1 💬 [4] Lysosome, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19 💬
104 Oxygen 💬[1] Oxygen[1] Oxygen--[13] 22, 49, 70, 85, 86, 88, 149, 168, 235, 271, 298, 299, 330 💬
105 Pabinafusp alfa 💬[1] Pabinafusp alfa[1] Pabinafusp alfa[2] IDS,
TFRC 💬 		[9] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Phagosome, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬[1] 19 💬
106 Paricalcitol 💬[1] Paricalcitol[1] Paricalcitol[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298 💬
107 Pegunigalsidase alfa 💬[1] Pegunigalsidase alfa[1] Pegunigalsidase alfa[1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬[1] 19 💬
108 Pentosan polysulfate sodium 💬[1] Pentosan polysulfate[2] Pentosan polysulfate; Pentosan polysulfate sodium--[2] 19, 26 💬
109 Prednisone 💬[1] Prednisone[2] Prednisona; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
110 Pyrimethamine 💬[1] Pyrimethamine[1] Pyrimethamine--[4] 2, 4, 19, 65 💬
111 Rimiducid 💬[1] Rimiducid[1] Rimiducid[1] CASP9 💬 [34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[7] 19, 49, 60, 65, 284, 285, 326 💬
112 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
113 Rivogenlecleucel 💬[1] Rivogenlecleucel[1] Rivogenlecleucel--[6] 19, 60, 65, 284, 285, 326 💬
114 Sebelipase alfa 💬[1] Sebelipase alfa[2] SBC-102; Sebelipase alfa[1] LIPA 💬 [4] Cholesterol metabolism, Efferocytosis, Lysosome, Steroid biosynthesis 💬[1] 19 💬
115 Sirolimus 💬[1] Sirolimus[2] Rapamycin; Sirolimus[1] MTOR 💬 [49] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[44] 2, 6, 13, 15, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
116 Somatropin 💬[1] Somatotropin[7] Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina[1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[26] 2, 3, 19, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
117 Taliglucerase alfa 💬[1] Taliglucerase alfa[2] Prgcd; Taliglucerase alfa[1] GBA 💬 [4] Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
118 Thiotepa 💬[1] Thiotepa[1] Thiotepa--[11] 13, 28, 46, 51, 60, 65, 85, 96, 107, 284, 285 💬
119 Tividenofusp alfa 💬[1] Tividenofusp alfa[1] Tividenofusp alfa[2] IDS,
TFRC 💬 		[9] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Phagosome, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬[1] 19 💬
120 Treosulfan 💬[1] Treosulfan[1] Treosulfan--[6] 13, 19, 62, 65, 284, 286 💬
121 Tropicamide 💬[1] Tropicamide[1] Tropicamide[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 19 💬
122 Velaglucerase alfa 💬[1] Velaglucerase alfa[2] GA-GCB; Velaglucerase alfa[1] GBA 💬 [4] Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
123 Velmanase alfa 💬[1] Velmanase alfa[3] Lamazym; Rhlaman; Velmanase alfa[1] MAN2B1 💬 [2] Lysosome, Other glycan degradation 💬[1] 19 💬
124 Venglustat 💬[1] Venglustat[2] Venglustat; Venglustat malate[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[3] 6, 19, 67 💬
125 Venglustat malate 💬[1] Venglustat[2] Venglustat; Venglustat malate--[3] 6, 19, 67 💬
126 Vestronidase alfa 💬[1] Vestronidase alfa[2] Recombinant human BETA-glucuronidase; Vestronidase alfa[1] uidA 💬 [6] Ascorbate and aldarate metabolism, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Pentose and glucuronate interconversions, Porphyrin metabolism 💬[1] 19 💬
127 Vitamin E 💬[1] Vitamin E[2] Alpha-tocopherol; Vitamin E--[6] 2, 19, 20, 49, 90, 206 💬
128 Vosoritide 💬[1] Vosoritide[1] Vosoritide[1] NPR2 💬 [5] Hormone signaling, Oxytocin signaling pathway, Purine metabolism, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 19, 276 💬
129 Warfarin 💬[1] Warfarin[3] Warfarin; Warfarin potassium; Warfarin sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[10] 6, 8, 19, 46, 49, 66, 85, 86, 88, 91 💬
130 Warfarin potassium 💬[1] Warfarin[3] Warfarin; Warfarin potassium; Warfarin sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[10] 6, 8, 19, 46, 49, 66, 85, 86, 88, 91 💬
131 Warfarin sodium 💬[1] Warfarin[3] Warfarin; Warfarin potassium; Warfarin sodium[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[10] 6, 8, 19, 46, 49, 66, 85, 86, 88, 91 💬
132 Water 💬[1] Water[1] Water--[25] 2, 5, 6, 13, 17, 19, 22, 46, 51, 53, 56, 57, 63, 64, 66, 67, 85, 96, 97, 206, 226, 230, 274, 278, 299 💬