Drug Description in Trials / DrugBank / KEGG DRUG

  

Search results

No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acamprosate 💬[1] Acamprosate[1] Acamprosate[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206 💬
2 Acetaminophen 💬[1] Acetaminophen[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
3 Acetylcysteine 💬[1] Acetylcysteine[3] ACETYLCYSTEINE; Mucomyst; N-acetylcysteine--[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
4 Ademetionine 💬[1] Ademetionine[2] SAM-e; SAMe--[2] 6, 93 💬
5 Agomelatine 💬[1] Agomelatine[1] Agomelatine[3] HTR2C,
MTNR1A,
MTNR1B 💬 		[6] Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
6 Alanine 💬[1] Alanine[2] Alanine; L-alanine--[4] 6, 13, 298, 299 💬
7 Albendazole 💬[1] Albendazole[2] Albendazole; Eskazole--[1] 96 💬
8 Allopurinol 💬[1] Allopurinol[2] ALLOPURINOL; ALLOPURINOL SODIUM[1] XDH 💬 [6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
9 Amantadine 💬[1] Amantadine[3] Amantadine; AMANTADINE HYDROCHLORIDE; GOCOVRI[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127 💬
10 Ambroxol 💬[1] Ambroxol[1] Ambroxol--[2] 6, 19 💬
11 Ammonia solution, strong 💬[1] Ammonia[1] Ammonia--[2] 6, 296 💬
12 Amoxicillin 💬[1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
13 Amoxicillin 💬[1] Amoxicillin[4] Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
14 Ampicillin 💬[1] Ampicillin[1] ABPC--[1] 84 💬
15 Ampreloxetine 💬[1] Ampreloxetine[1] Ampreloxetine[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
16 Anhydrous lactose 💬[1] Lactose[1] Lactose--[6] 2, 6, 13, 97, 228, 310 💬
17 Apomorphine 💬[1] Apomorphine[4] APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride[2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7 💬
18 Aripiprazole 💬[1] Aripiprazole[1] Aripiprazole[4] DRD2,
DRD3,
HTR1A,
HTR2A 💬 		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206 💬
19 Armodafinil 💬[1] Armodafinil[2] Armodafinil; Modafinil[1] SLC6A3 💬 [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[3] 6, 13, 84 💬
20 Aspartame 💬[1] Aspartame[0] [2] TAS1R2,
TAS1R3 💬 		[2] Carbohydrate digestion and absorption, Taste transduction 💬-
21 Atomoxetine 💬[1] Atomoxetine[2] Atomoxetine; Strattera[1] SLC6A2 💬 [1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
22 Azathioprine 💬[1] Azathioprine[3] Azathioprine; Azatioprina; Imuran--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
23 Bavisant 💬[1] Bavisant[1] Bavisant[1] HRH3 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 6 💬
24 Benserazide 💬[1] Benserazide[1] BENSERAZIDE[1] DDC 💬 [9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
25 Botulinum toxin type A 💬[1] Botulinum toxin type A[8] BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
26 Bromocriptine 💬[1] Bromocriptine[1] Bromocriptine[2] DRD2,
PRL 💬 		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 74 💬
27 Bumetanide 💬[1] Bumetanide[1] Bumetanide[1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 158 💬
28 Buspirone 💬[1] Buspirone[2] Buspirone; Buspirone Hydrochloride[2] DRD2,
HTR1A 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 51 💬
29 Cabergoline 💬[1] Cabergoline[3] CABERGOLINA; CABERGOLINE; DOSTINEX[2] DRD2,
PRL 💬 		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75 💬
30 Caffeine 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
31 Caffeine hydrate 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
32 Cannabidiol 💬[1] Cannabidiol[4] CANNABIDIOL; Epidiolex; Epidyolex; Sativex[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[19] 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
33 Capsaicin 💬[1] Capsaicin[2] Capsaicin; Qutenza[1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226 💬
34 Captopril 💬[1] Captopril[1] Captopril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[2] 17, 86 💬
35 Carbamazepine 💬[1] Carbamazepine[1] Carbamazepine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 6, 13, 231 💬
36 Carbidopa 💬[1] Carbidopa[8] Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] DDC 💬 [9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
37 Ceftriaxone 💬[1] Ceftriaxone[1] Ceftriaxone--[4] 2, 6, 46, 97 💬
38 Cholecalciferol 💬[1] Cholecalciferol[5] CHOLECALCIFEROL; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
39 Citalopram 💬[1] Citalopram[1] Citalopram[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
40 Citicoline 💬[1] Citicoline[1] Citicolina--[1] 6 💬
41 Clarithromycin 💬[1] Clarithromycin[1] Clarithromycin--[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
42 Clenbuterol 💬[1] Clenbuterol[1] Clenbuterol[1] ADRB2 💬 [9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 1, 2, 6, 256 💬
43 Clonazepam 💬[1] Clonazepam[1] Clonazepam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬
44 Clonidine 💬[1] Clonidine[4] Clonidin; Clonidina; Clonidine; Clonidine hydrochloride[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78 💬
45 Clozapine 💬[1] Clozapine[1] CLOZAPINE[11] ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[8] Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬[1] 6 💬
46 Cyanocobalamin 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
47 Cyanocobalamin Co 57 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
48 Cyanocobalamin Co 58 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
49 Cyanocobalamin Co 60 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
50 Dalfampridine 💬[1] Dalfampridine[7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; FAMPYRA[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14 💬
51 Darifenacin 💬[1] Darifenacin[2] Darifenacin; Emselex[1] CHRM3 💬 [11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13 💬
52 Deanol 💬[1] Deanol[1] Deanol--[1] 6 💬
53 Deferiprone 💬[1] Deferiprone[2] Deferiprone; Ferriprox--[6] 2, 6, 18, 120, 122, 233 💬
54 Delorazepam 💬[1] Delorazepam[0] [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬-
55 Desmopressin 💬[1] Desmopressin[5] DDAVP; Desmopressin; Desmopressin Acetate; Desmopressine; Minirin[2] AVPR2,
F8 💬 		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288 💬
56 Dexmedetomidine 💬[1] Dexmedetomidine[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
57 Dextromethorphan 💬[1] Dextromethorphan[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
58 Dihydroergotoxine 💬[1] Dihydroergotoxine[1] Dihydroergotoxine--[1] 6 💬
59 Dihydrotachysterol 💬[1] Dihydrotachysterol[0] [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬-
60 Dipivefrin 💬[1] Dipivefrin[2] Dipivefrin; Dipivefrine[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
61 Domperidone 💬[1] Domperidone[1] Domperidone[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
62 Domperidone maleate 💬[1] Domperidone[1] Domperidone[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
63 Donepezil 💬[1] Donepezil[3] Aricept; Donepezil; Donepezil hydrochloride[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
64 Dopamine 💬[1] Dopamine[2] Dopamina; Dopamine[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 299 💬
65 Doxepin 💬[1] Doxepin[1] Doxepin[3] HRH1,
SLC6A2,
SLC6A4 💬 		[5] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6 💬
66 Droxidopa 💬[1] Droxidopa[4] DOPS; Droxidopa; L-DOPS; Northera[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
67 Duloxetine 💬[1] Duloxetine[3] Cymbalta; DULOXETINE; Duloxetine hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13 💬
68 Edaravone 💬[1] Edaravone[3] Edaravone; Methylphenylpyrazolone; Norphenazone--[3] 2, 6, 22 💬
69 Elobixibat 💬[1] Elobixibat[1] Elobixibat[1] SLC10A2 💬 [1] Bile secretion 💬[1] 6 💬
70 Entacapone 💬[1] Entacapone[5] COMTAN; Comtess; ENTACAPONA; Entacapone; Stalevo[1] COMT 💬 [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
71 Erythromycin 💬[1] Erythromycin[1] Erythromycin--[5] 6, 36, 164, 228, 291 💬
72 Escitalopram 💬[1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
73 Eszopiclone 💬[1] Eszopiclone[2] Eszopiclone; Zopiclone[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46 💬
74 Etomidate 💬[1] Etomidate[1] Etomidate[1] GABRA1 💬 [6] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[1] 6 💬
75 Exametazime 💬[1] Exametazime[1] Exametazime--[1] 6 💬
76 Exenatide 💬[1] Exenatide[3] BYDUREON; Byetta; Exenatide[1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
77 Famotidine 💬[1] Famotidine[2] FAMOTIDINA; Famotidine[1] HRH2 💬 [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 86, 98, 107 💬
78 Febuxostat 💬[1] Febuxostat[1] Febuxostat[1] XDH 💬 [6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[3] 2, 6, 13 💬
79 Fesoterodine 💬[1] Fesoterodine[1] Fesoterodine[2] CHRM2,
CHRM3 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
80 Filgrastim 💬[1] Filgrastim[7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
81 Finasteride 💬[1] Finasteride[1] Finasteride[1] SRD5A2 💬 [3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6 💬
82 Flecainide 💬[1] Flecainide[3] Flecainide; FLECAINIDE ACETATE; Flecainidum[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
83 Fludrocortisone 💬[1] Fludrocortisone[1] Fludrocortisone[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
84 Flumazenil 💬[1] Flumazenil[1] Flumazenil[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
85 Folic acid 💬[1] Folic acid[5] Acide folique; Folate; Folic acid; Multivitamin; Nicotinamide--[6] 6, 41, 46, 49, 84, 296 💬
86 Foscarbidopa 💬[1] Foscarbidopa[1] Foscarbidopa--[1] 6 💬
87 Foslevodopa 💬[1] Foslevodopa[1] Foslevodopa[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
88 Furosemide 💬[1] Furosemide[2] Furosemide; Furosemide Injection[1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 86 💬
89 Gabapentin 💬[1] Gabapentin[4] Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
90 Galantamine 💬[1] Galantamine[2] Galantamine; Galantamine hydrobromide[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[2] 6, 127 💬
91 German chamomile flower 💬[1] Chamomile[2] Chamomile; MATRICARIA FLOWER--[2] 6, 97 💬
92 Glutathione 💬[1] Glutathione[2] Glutathione; Reduced Glutathione--[2] 6, 299 💬
93 Glycerin 💬[1] Glycerin[2] Bee venom; Glycerol--[5] 6, 13, 79, 316, 317 💬
94 Glycerol phenylbutyrate 💬[1] Glycerol phenylbutyrate[3] Glycerol Phenylbutyrate; GT4P; RAVICTI--[3] 6, 251, 299 💬
95 Green tea leaf 💬[1] Green tea leaf[4] Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract--[4] 6, 17, 28, 46 💬
96 Guar gum 💬[1] Guar gum[1] Guar gum--[1] 6 💬
97 Heptaminol 💬[1] Heptaminol[1] Heptaminol--[1] 6 💬
98 Hydrocortisone 💬[1] Hydrocortisone[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
99 Hydrocortisone cypionate 💬[1] Hydrocortisone cypionate[1] Cortef[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
100 Hydrocortisone succinate 💬[1] Hydrocortisone succinate[2] HYDROCORTISONE HYDROGEN SUCCINATE; Solu-Cortef[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
101 Idebenone 💬[1] Idebenone[2] IDEBENONE; Raxone--[6] 6, 8, 13, 18, 113, 302 💬
102 Iloperidone 💬[1] Iloperidone[1] Iloperidone[4] DRD2,
HTR2A,
HTR2B,
HTR2C 💬 		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 6 💬
103 Inosine 💬[1] Inosine[1] Inosine--[5] 2, 6, 13, 17, 122 💬
104 Inulin 💬[1] Inulin[1] Inulin--[4] 6, 96, 156, 299 💬
105 Iproniazid 💬[1] Iproniazid[1] IPRONIAZID[2] MAOA,
MAOB 💬 		[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
106 Isoflurane 💬[1] Isoflurane[1] Isoflurane--[1] 6 💬
107 Isradipine 💬[1] Isradipine[1] Isradipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
108 Istradefylline 💬[1] Istradefylline[1] ISTRADEFYLLINE[1] ADORA2A 💬 [7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
109 Josamycin 💬[1] Josamycin[0] ---
110 Ketamine 💬[1] Ketamine[2] KETAMINE; NMDA[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[6] 6, 13, 70, 113, 156, 215 💬
111 Lactobacillus casei 💬[1] Lactobacillus casei[2] Fusion; Lactobacillus casei--[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296 💬
112 Lactomin 💬[1] Lactobacillus acidophilus[4] Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus--[3] 6, 49, 97 💬
113 Lactose 💬[1] Lactose[1] Lactose--[6] 2, 6, 13, 97, 228, 310 💬
114 Leucine 💬[1] Leucine[2] L-leucine; Leucine--[6] 6, 19, 65, 283, 284, 299 💬
115 Levetiracetam 💬[1] Levetiracetam[2] KEPPRA; Levetiracetam[1] SV2A 💬 [1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
116 Levodopa 💬[1] Levodopa[9] Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; LEVODOPA; PARCOPA; SINEMET; SINEMET CR; Stalevo[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[6] 6, 17, 90, 140, 164, 201 💬
117 Levomefolic acid 💬[1] Levomefolic acid[1] L-methylfolate--[1] 6 💬
118 Liatermin 💬[1] Liatermin[2] Liatermin; R-metHuGDNF--[1] 6 💬
119 Lidocaine 💬[1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
120 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
121 Linaclotide 💬[1] Linaclotide[1] Linaclotide[1] GUCY2C 💬 [2] Metabolic pathways, Purine metabolism 💬[2] 6, 97 💬
122 Liraglutide 💬[1] Liraglutide[2] Liraglutide; Saxenda[1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 6, 75, 193 💬
123 Lisuride 💬[1] Lisuride[1] Lisuride[3] DRD2,
DRD3,
DRD4 💬 		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86 💬
124 Lithium citrate 💬[1] Lithium citrate[2] Lithium; LITHIUM CITRATE--[5] 2, 5, 6, 7, 8 💬
125 Lixisenatide 💬[1] Lixisenatide[1] Lixisenatide[1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
126 Lovastatin 💬[1] Lovastatin[1] Lovastatin[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
127 Lubiprostone 💬[1] Lubiprostone[1] Lubiprostone[1] CLCN2 💬 [1] Mineral absorption 💬[4] 6, 13, 290, 299 💬
128 Magnesium oxide 💬[1] Magnesium oxide[1] Magnesium Oxide--[3] 6, 166, 291 💬
129 Maltodextrin 💬[1] Maltodextrin[1] Maltodextrin--[4] 6, 13, 96, 97 💬
130 Mannitol 💬[1] Mannitol[4] Aridol; Bronchitol; Mannite; Mannitol--[7] 6, 13, 28, 60, 96, 113, 299 💬
131 Masitinib 💬[1] Masitinib[1] Masitinib[1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
132 Melatonin 💬[1] Melatonin[2] Circadin; Melatonin[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
133 Melevodopa 💬[1] Melevodopa[1] Melevodopa--[1] 6 💬
134 Melperone 💬[1] Melperone[1] Melperone[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
135 Memantine 💬[1] Memantine[3] EBIXA; MEMANTINE; MEMANTINE HYDROCHLORIDE[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
136 Metformin 💬[1] Metformin[5] Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
137 Methylphenidate 💬[1] Methylphenidate[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
138 Midazolam 💬[1] Midazolam[2] Midazolam; Midazolam injection[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
139 Midodrine 💬[1] Midodrine[2] Midodrine; MIDODRINE HYDROCHLORIDE[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58 💬
140 Minocycline 💬[1] Minocycline[3] Minocycline; MINOCYCLINE HYDROCHLORIDE; Minomycin--[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
141 Mirabegron 💬[1] Mirabegron[1] Mirabegron[1] ADRB3 💬 [8] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
142 Moclobemide 💬[1] Moclobemide[1] MOCLOBEMIDE[1] MAOA 💬 [14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
143 Modafinil 💬[1] Modafinil[2] Modafinil; Provigil--[5] 6, 13, 49, 93, 113 💬
144 Montelukast 💬[1] Montelukast[3] Montelukast; MONTELUKAST SODIUM; Singulair[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228 💬
145 Moxifloxacin 💬[1] Moxifloxacin[2] Moxifloxacin; Moxifloxacin Hydrochloride--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
146 Nabilone 💬[1] Nabilone[1] Nabilone[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 6, 13, 127 💬
147 Nadolol 💬[1] Nadolol[1] Nadolol[2] ADRB1,
ADRB2 💬 		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
148 Nalmefene 💬[1] Nalmefene[1] Nalmefene[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
149 Naloxone 💬[1] Naloxone[2] Naloxone; NALOXONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
150 Naltrexone 💬[1] Naltrexone[2] Naltrexone; Naltrexone Hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
151 Nelotanserin 💬[1] Nelotanserin[1] Nelotanserin[1] HTR2A 💬 [5] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
152 Niacin 💬[1] Niacin[2] Niacin; Nicotinic acid--[3] 6, 78, 79 💬
153 Niacinamide 💬[1] Nicotinamide[3] Multivitamin; Niacinamide; Nicotinamide--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
154 Nicotine 💬[1] Nicotine[2] Nicotine; Nicotine gum[16] CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬 		[8] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬[3] 6, 13, 84 💬
155 Nilotinib 💬[1] Nilotinib[2] Nilotinib; TASIGNA[4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬 		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86 💬
156 Nitisinone 💬[1] Nitisinone[2] Nitisinone; Orfadin[1] HPD 💬 [5] Biosynthesis of cofactors, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬[3] 6, 164, 241 💬
157 Nitric oxide 💬[1] Nitric Oxide[3] INOmax; NITRIC OXIDE; Nitrosyl--[7] 85, 86, 88, 210, 251, 294, 299 💬
158 Nitrogen 💬[1] Nitrogen[1] Nitrogen--[5] 5, 6, 17, 211, 299 💬
159 Nortriptyline 💬[1] Nortriptyline[2] Nortriptyline; Nortriptyline hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226 💬
160 Omeprazole 💬[1] Omeprazole[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
161 Ondansetron 💬[1] Ondansetron[1] Ondansetron[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107 💬
162 Opicapone 💬[1] Opicapone[2] Ongentys; OPICAPONE[1] COMT 💬 [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6 💬
163 Oxiglutatione 💬[1] Glutathione[2] Glutathione; Reduced Glutathione--[2] 6, 299 💬
164 Oxybuprocaine 💬[1] Oxybuprocaine[1] Oxybuprocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
165 Oxybutynin 💬[1] Oxybutynin[1] Oxybutynin[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
166 Oxycodone 💬[1] Oxycodone[2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
167 Oxygen 💬[1] Oxygen[3] Medical air; Nitrogen; Oxygen--[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330 💬
168 Oxytocin 💬[1] Oxytocin[2] Oxytocin; Syntocinon[1] OXTR 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226 💬
169 Pardoprunox 💬[1] Pardoprunox[1] Pardoprunox[3] DRD2,
DRD3,
HTR1A 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
170 Paroxetine 💬[1] Paroxetine[1] Paroxetine[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85 💬
171 Perampanel 💬[1] Perampanel[2] Fycompa; Perampanel[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144 💬
172 Pergolide 💬[1] Pergolide[1] PERGOLIDE[2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
173 Phenelzine 💬[1] Phenelzine[1] Nardil[2] MAOA,
MAOB 💬 		[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
174 Pilocarpine 💬[1] Pilocarpine[2] Pilocarpine; Pilocarpine Hydrochloride[2] CHRM2,
CHRM3 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299 💬
175 Pioglitazone 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
176 Piribedil 💬[1] Piribedil[1] Piribedil[2] DRD2,
DRD3 💬 		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
177 Pitolisant 💬[1] Pitolisant[1] Pitolisant[1] HRH3 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193 💬
178 Plantago seed 💬[1] Plantago seed[2] Psyllium; Psyllium husk--[3] 6, 28, 97 💬
179 Polyethylene glycol 3350 💬[1] Polyethylene glycol[4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350--[7] 6, 78, 96, 97, 235, 276, 299 💬
180 Potassium carbonate 💬[1] Potassium carbonate[0] ---
181 Pramipexole 💬[1] Pramipexole[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[3] DRD2,
DRD3,
DRD4 💬 		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20 💬
182 Prasinezumab 💬[1] Prasinezumab[1] Prasinezumab[1] SNCA 💬 [3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 6 💬
183 Preladenant 💬[1] Preladenant[1] Preladenant[1] ADORA2A 💬 [7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
184 Pridopidine 💬[1] Pridopidine[1] Pridopidine[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8 💬
185 Propofol 💬[1] Propofol[2] Propofol; Propofol Injection[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[8] 6, 21, 22, 34, 46, 70, 98, 296 💬
186 Propranolol 💬[1] Propranolol[2] Propanolol; Propranolol[3] ADRB1,
ADRB2,
ADRB3 💬 		[12] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 158, 167, 227, 278, 296 💬
187 Pyridoxine 💬[1] Pyridoxine[2] Pyridoxine; Vitamin B6--[5] 6, 93, 145, 206, 320 💬
188 Pyrimethamine 💬[1] Pyrimethamine[2] Daraprim; Pyrimethamine--[4] 2, 4, 19, 65 💬
189 Quetiapine 💬[1] Quetiapine[2] Quetiapine; Seroquel[2] DRD2,
HTR2A 💬 		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13 💬
190 Quinine 💬[1] Quinine[0] ---
191 Quinine dihydrochloride 💬[1] Quinine[0] ---
192 Ramelteon 💬[1] Ramelteon[2] Ramelteon; ROZEREM[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46 💬
193 Rasagiline 💬[1] Rasagiline[4] Azilect; Rasagilina; Rasagiline; RASAGILINE MESYLATE[1] MAOB 💬 [14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
194 Rasagiline tartrate 💬[1] Rasagiline[4] Azilect; Rasagilina; Rasagiline; RASAGILINE MESYLATE[1] MAOB 💬 [14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
195 Remifentanil 💬[1] Remifentanil[2] Remifentanil; Remifentanyl[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[2] 6, 70 💬
196 Repaglinide 💬[1] Repaglinide[1] Repaglinide[2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
197 Rifampin 💬[1] Rifampicin[2] RIFAMPICIN; Rifampin--[9] 6, 13, 17, 46, 84, 86, 93, 299, 338 💬
198 Rifaximin 💬[1] Rifaximin[3] Rifaximin; RIFAXIMINA; Xifaxan--[9] 6, 65, 93, 94, 96, 97, 99, 296, 299 💬
199 Rimabotulinumtoxin B 💬[1] Botulinum toxin type B[3] Botulinum toxin type B; MYOBLOC; NEUROBLOC[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[4] 2, 6, 13, 51 💬
200 Rivastigmine 💬[1] Rivastigmine[3] EXELON; RIVASTIGMINE; Rivastigmine Transdermal System[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13 💬
201 Ropinirole 💬[1] Ropinirole[3] REQUIP; Ropinirole; Ropinirole Hydrochloride[3] DRD2,
DRD3,
DRD4 💬 		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 309 💬
202 Rosuvastatin 💬[1] Rosuvastatin[3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
203 Rotigotine 💬[1] Rotigotine[3] NEUPRO; ROTIGOTINA; ROTIGOTINE[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
204 Safinamide 💬[1] Safinamide[3] Safinamida; SAFINAMIDE; Xadago[1] MAOB 💬 [14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
205 Saracatinib 💬[1] Saracatinib[1] Saracatinib[2] ABL1,
SRC 💬 		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[3] 6, 89, 272 💬
206 Sargramostim 💬[1] Sargramostim[2] Leukine; Sargramostim[1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
207 Selegiline 💬[1] Selegiline[2] SELEGILINE; Zelapar[1] MAOB 💬 [14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
208 Semaglutide 💬[1] Semaglutide[1] Semaglutide[1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
209 Serine 💬[1] Serine[2] L-Serine; Serine--[4] 2, 6, 86, 96 💬
210 Sertraline 💬[1] Sertraline[1] Sertraline[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206 💬
211 Sevoflurane 💬[1] Sevoflurane[1] Sevoflurane--[7] 6, 21, 22, 34, 98, 225, 296 💬
212 Sildenafil 💬[1] Sildenafil[6] Mysildecard; Revatio; Sildenafil; Sildenafil Citrate; SILDENAFILO; Viagra[1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
213 Silodosin 💬[1] Silodosin[2] Silodosin; Silodyx[1] ADRA1A 💬 [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 6, 13 💬
214 Simvastatin 💬[1] Simvastatin[3] SIMVASTATIN; Simvastatina; Simvastatine[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
215 Sitagliptin 💬[1] Sitagliptin[1] Sitagliptin[1] DPP4 💬 [1] Protein digestion and absorption 💬[4] 6, 75, 233, 299 💬
216 Sodium chloride 💬[1] Sodium chloride[6] Lactated Ringers; Natriumchlorid; REBIF; SALINE; SODIUM CHLORIDE; SPORANOX--[20] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬
217 Sodium oxybate 💬[1] Sodium oxybate[1] Sodium Oxybate--[2] 6, 149 💬
218 Solifenacin 💬[1] Solifenacin[2] Solifenacin; Solifenacin Succinate[1] CHRM3 💬 [11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
219 Sulfachlorpyridazine 💬[1] Sulfachlorpyridazine[0] ---
220 Sulfanilamide 💬[1] Sulfanilamide[0] ---
221 Sulpiride 💬[1] Sulpiride[0] [1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬-
222 Suvorexant 💬[1] Suvorexant[1] Suvorexant[2] HCRTR1,
HCRTR2 💬 		[1] Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13 💬
223 Tacrolimus 💬[1] Tacrolimus[2] Prograf; Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
224 Tacrolimus 💬[1] Tacrolimus[2] Prograf; Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
225 Tadalafil 💬[1] Tadalafil[4] Adcirca; CIALIS; TADALAFIL; TADALAFILO[1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210 💬
226 Talampanel 💬[1] Talampanel[1] Talampanel[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6 💬
227 Tavapadon 💬[1] Tavapadon[2] PF-06649751; TAVAPADON[2] DRD1,
DRD5 💬 		[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6 💬
228 Terazosin 💬[1] Terazosin[1] Terazosin[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 6 💬
229 Tolcapone 💬[1] Tolcapone[3] Tasmar; Tolcapon; TOLCAPONE[1] COMT 💬 [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[3] 6, 28, 127 💬
230 Topiramate 💬[1] Topiramate[2] TOPAMAX; Topiramate[36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬
231 Tozadenant 💬[1] Tozadenant[1] TOZADENANT[1] ADORA2A 💬 [7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
232 Trihexyphenidyl 💬[1] Trihexyphenidyl[1] Trihexyphenidyl[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6 💬
233 Trimethobenzamide 💬[1] Trimethobenzamide[3] Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride--[1] 6 💬
234 Tropicamide 💬[1] Tropicamide[1] Tropicamide[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
235 Tryptophan 💬[1] Tryptophan[2] Propanoic acid; Tryptophan--[1] 6 💬
236 Tulobuterol 💬[1] Tulobuterol[1] Tulobuterol[1] ADRB2 💬 [9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
237 Tyrosine 💬[1] Tyrosine[4] Alanine; L-tyrosine; Propanoic acid; Tyrosine--[4] 6, 86, 111, 298 💬
238 Ubidecarenone 💬[1] Ubidecarenone[3] Coenzyme Q-10; Coenzyme Q10; CoQ10--[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
239 Ursodiol 💬[1] Ursodeoxycholic acid[4] UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk[1] NR1H4 💬 [1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
240 Valiloxybate 💬[1] Valiloxybate[1] Valiloxybate[2] GABBR1,
GABBR2 💬 		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
241 Valproic acid 💬[1] Valproic acid[3] Valproate; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬
242 Varenicline 💬[1] Varenicline[2] Champix; Varenicline[2] CHRNA4,
CHRNB2 💬 		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[3] 6, 18, 53 💬
243 Venglustat 💬[1] Venglustat[2] GENZ-682452; Venglustat[1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism 💬[3] 6, 19, 67 💬
244 Venlafaxine 💬[1] Venlafaxine[2] Venlafaxine; Venlafaxine Hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46 💬
245 Vitamin E 💬[1] Vitamin E[2] Alpha-tocopherol; Vitamin E--[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
246 Vortioxetine 💬[1] Vortioxetine[1] Vortioxetine[7] HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬 		[5] Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
247 Warfarin 💬[1] Warfarin[2] Warfarin; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
248 Water 💬[1] Water[8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
249 Wheat 💬[1] Wheat[1] Wheat--[2] 6, 53 💬
250 Yohimbine 💬[1] Yohimbine[1] Yohimbine[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 6 💬
251 Zoledronic acid 💬[1] Zoledronic acid[4] ACLASTA; Zoledronate; Zoledronic acid; Zometa[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
252 Zoledronic acid 💬[1] Zoledronic acid[4] Aclasta; Zoledronate; Zoledronic acid; Zometa[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
253 Zolmitriptan 💬[1] Zolmitriptan[1] Zolmitriptan[2] HTR1B,
HTR1D 💬 		[4] Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
254 Zolpidem 💬[1] Zolpidem[2] Zolpidem; Zolpidem Tartrate[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46 💬
255 Zonisamide 💬[1] Zonisamide[2] Zonegran; Zonisamide[8] CACNA1G,
CACNA1H,
CACNA1I,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[11] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus 💬[1] 6 💬
256 Zopiclone 💬[1] Zopiclone[1] Zopiclone[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬