Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 7-beta-Hydroxyepiandrosterone [1] 7-beta-Hydroxyepiandrosterone---[1] 6 💬
2 Acamprosate [2] Acamprosate; Acamprosate calcium[2] Acamprosate calcium ,
Acamprosate 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 6, 206 💬
3 Acetate [1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
4 Acetylcysteine [4] Acetylcysteine; N acetyl cysteine; N-Acetyl cysteine; N-acetylcysteine[1] Acetylcysteine 💬 --[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
5 Agomelatine [1] Agomelatine[1] Agomelatine 💬 [3] HTR2C,
MTNR1A,
MTNR1B 💬 		[7] Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
6 Alanine [2] Alanine; L-alanine[1] Alanine 💬 --[8] 6, 13, 70, 94, 97, 251, 298, 299 💬
7 Allopurinol [2] Allopurinol; ALLOPURINOL SODIUM[2] Allopurinol ,
Allopurinol sodium 💬 		[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
8 Alovudine [1] Alovudine[1] Alovudine 💬 --[1] 6 💬
9 Altanserin [1] Altanserin---[1] 6 💬
10 Altropane [1] Altropane---[1] 6 💬
11 Amantadine [3] Amantadine; AMANTADINE HYDROCHLORIDE; Amantadine sulfate[2] Amantadine hydrochloride ,
Amantadine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[5] 2, 6, 8, 13, 127 💬
12 Ambroxol [2] Ambroxol; Ambroxol Hydrochloride[2] Ambroxol hydrochloride ,
Ambroxol 💬 		--[3] 2, 6, 19 💬
13 Amino acids [1] Amino acids---[6] 6, 70, 90, 113, 240, 298 💬
14 Ammonia [1] Ammonia[1] Ammonia solution, strong 💬 --[6] 6, 17, 86, 88, 251, 296 💬
15 Amoxicillin [2] Amoxicilina; AMOXICILLIN[3] Amoxicillin ,
Amoxicillin sodium ,
Amoxicillin 💬 		--[9] 6, 46, 63, 94, 96, 97, 222, 223, 299 💬
16 Ampreloxetine [1] Ampreloxetine[1] Ampreloxetine 💬 [2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
17 Apigenin [1] Apigenin---[3] 6, 46, 97 💬
18 Aplindore [1] Aplindore[1] Aplindore fumarate 💬 [2] DRD2,
DRD3 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
19 Apomorphine [2] Apomorphine; APOMORPHINE HYDROCHLORIDE[2] Apomorphine hydrochloride ,
Apomorphine 💬 		[2] DRD1,
DRD2 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7 💬
20 Aripiprazole [1] Aripiprazole[1] Aripiprazole 💬 [4] DRD2,
DRD3,
HTR1A,
HTR2A 💬 		[14] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[3] 6, 74, 206 💬
21 Armodafinil [2] Armodafinil; Modafinil[1] Armodafinil 💬 [1] SLC6A3 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[3] 6, 13, 84 💬
22 Atomoxetine [1] Atomoxetine[2] Atomoxetine hydrochloride ,
Atomoxetine 💬 		[1] SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
23 AV-101 [1] AV-101---[2] 6, 86 💬
24 Azathioprine [2] Azathioprine; AZATIOPRINA[2] Azathioprine ,
Azathioprine sodium 💬 		--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
25 AZD-0328 [0] ---[1] 6 💬
26 Bacillus coagulans [1] Bacillus coagulans---[1] 6 💬
27 Bacillus licheniformis [1] Bacillus licheniformis---[1] 6 💬
28 Bacillus subtilis [1] Bacillus subtilis---[3] 6, 28, 96 💬
29 Barium [1] Barium---[5] 2, 6, 19, 97, 98 💬
30 Bavisant [1] Bavisant[1] Bavisant 💬 [1] HRH3 💬 [2] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 6 💬
31 Befiradol [1] BEFIRADOL---[1] 6 💬
32 Benserazide [2] BENSERAZIDE; BENSERAZIDE HYDROCHLORIDE[2] Benserazide hydrochloride ,
Benserazide 💬 		[1] DDC 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
33 Benzofuran [1] Benzofuran---[1] 6 💬
34 BIA [1] BIA---[4] 6, 86, 96, 299 💬
35 Botulinum toxin type A [5] Botulinum toxin A; BOTULINUM TOXIN TYPE A; IncobotulinumtoxinA; Onabotulinumtoxin A; OnabotulinumtoxinA[4] Botulinum toxin type A ,
OnabotulinumtoxinA ,
AbobotulinumtoxinA ,
Incobotulinumtoxin A 💬 		[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
36 Botulinum toxin type B [1] Botulinum toxin type B[1] RimabotulinumtoxinB 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[3] 2, 6, 51 💬
37 Bromocriptine [1] Bromocriptine[2] Bromocriptine mesylate ,
Bromocriptine 💬 		[2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 57, 74 💬
38 BTRX-246040 [1] BTRX-246040---[1] 6 💬
39 Bumetanide [1] Bumetanide[1] Bumetanide 💬 [1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[4] 6, 57, 115, 158 💬
40 Buspirone [2] Buspirone; Buspirone Hydrochloride[2] Buspirone hydrochloride ,
Buspirone 💬 		[2] DRD2,
HTR1A 💬 		[12] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[3] 6, 51, 179 💬
41 Butylphthalide [2] 3-N-butylphthalide; Butylphthalide---[4] 2, 6, 17, 22 💬
42 Cabergoline [2] CABERGOLINA; Cabergoline[1] Cabergoline 💬 [2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 74, 75, 77 💬
43 Caffeine [1] Caffeine[2] Caffeine ,
Caffeine citrate 💬 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
44 Calcium [1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
45 Cannabidiol [1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
46 Capsaicin [1] Capsaicin[1] Capsaicin 💬 [1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226 💬
47 Carbamazepine [1] Carbamazepine[1] Carbamazepine 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[6] 6, 13, 137, 145, 158, 231 💬
48 Carbidopa [1] Carbidopa[1] Carbidopa 💬 [1] DDC 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
49 Carfentanil [1] Carfentanil[2] Carfentanil citrate ,
Carfentanil 💬 		[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 6 💬
50 Carnosine [1] Carnosine---[2] 6, 13 💬
51 Carvedilol [1] CARVEDILOL[2] Carvedilol ,
Carvedilol phosphate 💬 		[5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		[15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 46, 57, 58, 86, 113, 210 💬
52 Ceftriaxone [1] Ceftriaxone[2] Ceftriaxone sodium ,
Ceftriaxone 💬 		--[4] 2, 6, 97, 299 💬
53 Celecoxib [1] Celecoxib[1] Celecoxib 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
54 CEP-1347 [1] CEP-1347---[1] 6 💬
55 CERE-120 [1] CERE-120---[1] 6 💬
56 Chamomile [1] Chamomile[1] German chamomile flower 💬 --[1] 6 💬
57 Cilostazol [1] Cilostazol[1] Cilostazol 💬 [3] PDE3A,
PDE3B,
TBXA2R 💬 		[13] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 48, 51, 70, 124 💬
58 Citalopram [1] Citalopram[2] Citalopram hydrobromide ,
Citalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
59 Clarithromycin [1] Clarithromycin[1] Clarithromycin 💬 --[10] 6, 46, 63, 84, 96, 97, 222, 223, 228, 299 💬
60 Clenbuterol [2] Clenbuterol; CLENBUTEROL HYDROCHLORIDE[2] Clenbuterol hydrochloride ,
Clenbuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 1, 2, 6, 57, 113, 256 💬
61 Clonazepam [1] Clonazepam[1] Clonazepam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬
62 Clonidine [2] Clonidine; Clonidine hydrochloride[2] Clonidine ,
Clonidine hydrochloride 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[3] 6, 65, 70 💬
63 Clozapine [1] CLOZAPINE[1] Clozapine 💬 [11] ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[10] Calcium signaling pathway, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬[1] 6 💬
64 Cocoa [2] Chocolate; Cocoa---[1] 6 💬
65 Creatine [3] Acetic acid; Creatine; Creatine monohydrate---[18] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 97, 113, 156, 201, 256, 337 💬
66 Crisugabalin [1] Crisugabalin---[2] 6, 13 💬
67 Crocin [1] Crocin---[1] 6 💬
68 CVN-424 [0] ---[1] 6 💬
69 Cysteine [2] Cysteine; Cysteine hydrochloride[2] L-Cysteine ,
Cysteine hydrochloride 💬 		--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
70 D-Serine [1] D-Serine---[1] 6 💬
71 Dapagliflozin [1] Dapagliflozin[1] Dapagliflozin 💬 --[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
72 Dapansutrile [1] Dapansutrile[1] Dapansutrile 💬 --[1] 6 💬
73 Daridorexant [1] Daridorexant[2] Daridorexant ,
Daridorexant hydrochloride 💬 		[2] HCRTR1,
HCRTR2 💬 		[2] Hormone signaling, Neuroactive ligand-receptor interaction 💬[1] 6 💬
74 Darifenacin [1] Darifenacin[2] Darifenacin hydrobromide ,
Darifenacin 💬 		[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[4] 2, 6, 13, 26 💬
75 Deanol [1] Deanol[1] Deanol 💬 --[1] 6 💬
76 Deferiprone [1] Deferiprone[1] Deferiprone 💬 --[7] 2, 6, 18, 121, 122, 139, 233 💬
77 Desmopressin [2] Desmopressin; Desmopressin acetate[2] Desmopressin ,
Desmopressin acetate 💬 		[2] AVPR2,
F8 💬 		[5] Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[8] 6, 22, 64, 72, 75, 223, 225, 288 💬
78 Dexmedetomidine [4] DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; Imidazole[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
79 Dextromethorphan [2] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE[3] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Dextromethorphan polistirex 💬 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
80 Dihydroergotoxine [1] Dihydroergotoxine[1] Dihydroergotoxine 💬 --[1] 6 💬
81 Dipivefrin [1] Dipivefrin[2] Dipivefrin hydrochloride ,
Dipivefrin 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
82 Dipraglurant [1] Dipraglurant---[1] 6 💬
83 Domperidone [1] Domperidone[2] Domperidone ,
Domperidone maleate 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
84 Donepezil [2] Donepezil; Donepezil hydrochloride[2] Donepezil hydrochloride ,
Donepezil 💬 		[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[8] 5, 6, 13, 46, 124, 127, 156, 206 💬
85 Dopamine [1] Dopamine[2] Dopamine hydrochloride ,
Dopamine 💬 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 7, 17, 74, 77 💬
86 Doxepin [1] Doxepin[2] Doxepin hydrochloride ,
Doxepin 💬 		[3] HRH1,
SLC6A2,
SLC6A4 💬 		[6] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6 💬
87 Droxidopa [2] Droxidopa; L-DOPS[1] Droxidopa 💬 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
88 Duloxetine [2] Duloxetine; Duloxetine hydrochloride[2] Duloxetine hydrochloride ,
Duloxetine 💬 		[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 97 💬
89 Edaravone [3] EDARAVONE; Methylphenylpyrazolone; Norphenazone[1] Edaravone 💬 --[3] 2, 6, 22 💬
90 Eliprodil [1] Eliprodil---[1] 6 💬
91 Elobixibat [1] Elobixibat[1] Elobixibat 💬 [1] SLC10A2 💬 [1] Bile secretion 💬[1] 6 💬
92 Eltoprazine [2] ELTOPRAZINE; Eltoprazine Hydrochloride---[1] 6 💬
93 Entacapone [2] ENTACAPONA; ENTACAPONE[1] Entacapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
94 EPI-589 [1] EPI-589---[2] 2, 6 💬
95 Erythromycin [1] Erythromycin[7] Erythromycin ,
Erythromycin estolate ,
Erythromycin ethylsuccinate ,
Erythromycin lactobionate ,
Erythromycin stearate ,
Erythromycin gluceptate ,
Erythromycin thiocyanate 💬 		--[6] 2, 6, 36, 164, 228, 291 💬
96 Erythropoietin [3] EPOETIN ALFA; Erythropoietin; RhEPO[4] Epoetin alfa ,
Epoetin epsilon ,
Epoetin theta ,
Epoetin zeta 💬 		[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
97 Escitalopram [3] Citalopram; Escitalopram; Escitalopram oxalate[2] Escitalopram oxalate ,
Escitalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[5] 2, 6, 13, 46, 77 💬
98 Esketamine [3] Esketamine; Esketamine hydrochloride; KETAMINE[2] Esketamine ,
Esketamine hydrochloride 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 4, 6, 70, 96, 97, 156 💬
99 Esomeprazole [3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[5] Esomeprazole magnesium ,
Esomeprazole sodium ,
Esomeprazole ,
Esomeprazole strontium ,
Esomeprazole magnesium dihydrate 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
100 Eszopiclone [2] Eszopiclone; Zopiclone[1] Eszopiclone 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46 💬
101 Etomidate [1] Etomidate[1] Etomidate 💬 [1] GABRA1 💬 [8] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[2] 6, 11 💬
102 Etoricoxib [1] Etoricoxib[1] Etoricoxib 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 6, 46, 70, 165, 271 💬
103 Exametazime [1] Exametazime[1] Exametazime 💬 --[1] 6 💬
104 Exenatide [1] Exenatide[1] Exenatide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
105 Exidavnemab [1] Exidavnemab---[2] 6, 17 💬
106 Famotidine [1] Famotidine[1] Famotidine 💬 [1] HRH2 💬 [4] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[7] 6, 46, 86, 98, 107, 145, 300 💬
107 Fasudil [2] Fasudil; Fasudil hydrochloride[2] Fasudil hydrochloride ,
Fasudil 💬 		[2] ROCK1,
ROCK2 💬 		[25] Adherens junction, Axon guidance, Cadherin signaling, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 2, 5, 6, 7, 51 💬
108 FB-101 [1] FB-101---[1] 6 💬
109 Febuxostat [1] Febuxostat[2] Febuxostat ,
Febuxostat hydrate 💬 		[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[5] 2, 6, 13, 67, 97 💬
110 Fecal microbiota [3] Fecal microbial transplantation; Fecal microbiota; Fecal Microbiota Transplantation---[14] 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 222, 271, 298 💬
111 Fesoterodine [1] Fesoterodine[2] Fesoterodine ,
Fesoterodine fumarate 💬 		[2] CHRM2,
CHRM3 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
112 Fexofenadine [1] Fexofenadine[2] Fexofenadine hydrochloride ,
Fexofenadine 💬 		[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[4] 6, 13, 19, 46 💬
113 Filgrastim [4] Filgrastim; G-CSF; Gcsf; GRANULOCYTE COLONY STIMULATING FACTOR[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[30] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
114 Finasteride [1] Finasteride[1] Finasteride 💬 [1] SRD5A2 💬 [2] Prostate cancer, Steroid hormone biosynthesis 💬[1] 6 💬
115 Fipamezole [1] Fipamezole---[2] 6, 17 💬
116 Flecainide [3] Flecainide; FLECAINIDE ACETATE; Flecainidum[2] Flecainide acetate ,
Flecainide 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[2] 6, 115 💬
117 Fludrocortisone [1] Fludrocortisone[2] Fludrocortisone acetate ,
Fludrocortisone 💬 		[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
118 Flumazenil [1] Flumazenil[1] Flumazenil 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
119 Flutemetamol [1] Flutemetamol---[6] 2, 5, 6, 7, 17, 127 💬
120 Folic acid [4] Acide folique; Folacin; Folate; Folic acid[2] Folic acid ,
Folate sodium 💬 		--[9] 6, 46, 49, 50, 84, 97, 118, 172, 296 💬
121 Foliglurax [1] Foliglurax---[1] 6 💬
122 Foscarbidopa [1] Foscarbidopa[1] Foscarbidopa 💬 --[1] 6 💬
123 Foslevodopa [1] Foslevodopa[1] Foslevodopa 💬 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
124 Furosemide [1] FUROSEMIDE[1] Furosemide 💬 [1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[5] 6, 57, 77, 86, 222 💬
125 Fursultiamine [1] Fursultiamine[2] Fursultiamine ,
Fursultiamine hydrochloride 💬 		--[2] 6, 18 💬
126 Gabapentin [3] GABAPENTIN; GABAPENTINA; Gabapentine[1] Gabapentin 💬 [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[10] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[7] 6, 13, 18, 19, 70, 226, 298 💬
127 Galantamine [2] GALANTAMINE; Galantamine hydrobromide[2] Galantamine hydrobromide ,
Galantamine 💬 		[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[3] 6, 11, 127 💬
128 Gemfibrozil [1] Gemfibrozil[1] Gemfibrozil 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 6, 13 💬
129 Glutathione [2] GLUTATHIONE; Reduced glutathione[1] Glutathione 💬 --[2] 6, 299 💬
130 Glycerol phenylbutyrate [1] Glycerol Phenylbutyrate[1] Glycerol phenylbutyrate 💬 --[2] 6, 7 💬
131 Gold [1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
132 GPI-1485 [0] ---[1] 6 💬
133 Grapefruit [1] Grapefruit---[5] 6, 46, 50, 83, 97 💬
134 Guar gum [1] Guar gum[1] Guar gum 💬 --[1] 6 💬
135 Hemoglobin [1] Hemoglobin---[3] 6, 60, 283 💬
136 Heptaminol [2] Heptaminol; Heptaminol hydrochloride[2] Heptaminol ,
Heptaminol hydrochloride 💬 		--[1] 6 💬
137 HOV-12020 [1] HOV-12020---[2] 6, 124 💬
138 Hydrocortisone [3] Cortisol; HYDROCORTISONE; Hydrocortisonum[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
139 Hydrogen [1] Hydrogen---[8] 5, 6, 13, 17, 83, 97, 226, 238 💬
140 Hydroxychloroquine [2] Hydroxychloroquine; Hydroxychloroquine sulfate[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
141 Idebenone [1] Idebenone[1] Idebenone 💬 --[9] 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
142 Iloperidone [1] Iloperidone[1] Iloperidone 💬 [4] DRD2,
HTR2A,
HTR2B,
HTR2C 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 6 💬
143 Inosine [1] Inosine[1] Inosine 💬 --[5] 2, 6, 13, 17, 122 💬
144 Inulin [1] Inulin[1] Inulin 💬 --[5] 6, 96, 97, 156, 299 💬
145 Ipratropium [1] Ipratropium---[2] 6, 86 💬
146 Iproniazid [1] IPRONIAZID[2] Iproniazid ,
Iproniazid phosphate 💬 		[2] MAOA,
MAOB 💬 		[13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
147 Isoflurane [1] Isoflurane[1] Isoflurane 💬 --[1] 6 💬
148 Isradipine [1] Isradipine[1] Isradipine 💬 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
149 Istradefylline [1] ISTRADEFYLLINE[1] Istradefylline 💬 [1] ADORA2A 💬 [8] Alcoholism, Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
150 Itraconazole [1] Itraconazole[1] Itraconazole 💬 --[13] 2, 3, 6, 46, 65, 67, 96, 97, 137, 158, 227, 299, 309 💬
151 KDT-3594 [1] KDT-3594---[1] 6 💬
152 Ketamine [2] KETAMINE; Ketamine hydrochloride[2] Ketamine hydrochloride ,
Ketamine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[6] 6, 13, 70, 113, 156, 215 💬
153 KW-6356 [1] KW-6356---[1] 6 💬
154 Lactobacillus acidophilus [1] Lactobacillus acidophilus[1] Lactomin 💬 --[1] 6 💬
155 Lactobacillus casei [1] Lactobacillus casei[1] Lactobacillus casei 💬 --[3] 6, 97, 296 💬
156 Lactobacillus plantarum [1] Lactobacillus plantarum---[3] 6, 97, 156 💬
157 Lactose [2] Lactose; Lactose monohydrate[2] Anhydrous lactose ,
Lactose hydrate 💬 		--[8] 2, 6, 13, 21, 97, 107, 228, 310 💬
158 Lactulose [1] Lactulose[1] Lactulose 💬 --[5] 6, 13, 96, 97, 291 💬
159 Lecanemab [1] Lecanemab[1] Lecanemab 💬 [1] APP 💬 [4] Alzheimer disease, IgSF CAM signaling, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse 💬[1] 6 💬
160 Lemborexant [1] Lemborexant[1] Lemborexant 💬 [2] HCRTR1,
HCRTR2 💬 		[2] Hormone signaling, Neuroactive ligand-receptor interaction 💬[2] 6, 127 💬
161 Lenrispodun [1] Lenrispodun[1] Lenrispodun 💬 [3] PDE1A,
PDE1B,
PDE1C 💬 		[6] Calcium signaling pathway, Morphine addiction, Olfactory transduction, Purine metabolism, Renin secretion, Taste transduction 💬[1] 6 💬
162 Leptin [1] Leptin---[2] 6, 265 💬
163 Leucine [2] L-leucine; Leucine[1] Leucine 💬 --[13] 5, 6, 7, 18, 19, 65, 96, 97, 127, 280, 283, 284, 299 💬
164 Levetiracetam [1] Levetiracetam[1] Levetiracetam 💬 [1] SV2A 💬 [1] ECM-receptor interaction 💬[7] 2, 4, 6, 13, 34, 149, 307 💬
165 Levodopa [2] L-DOPA; Levodopa[1] Levodopa 💬 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 5, 6, 17, 90, 120, 140, 164, 201 💬
166 Liatermin [2] Liatermin; R-metHuGDNF[1] Liatermin 💬 --[1] 6 💬
167 Lidocaine [2] Lidocaine; Lidocaine hydrochloride[3] Lidocaine ,
Lidocaine hydrochloride ,
Lidocaine hydrochloride monohydrate 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
168 Linaclotide [1] Linaclotide[2] Linaclotide acetate ,
Linaclotide 💬 		[1] GUCY2C 💬 [2] Hormone signaling, Purine metabolism 💬[3] 6, 97, 299 💬
169 Liraglutide [1] Liraglutide[1] Liraglutide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 6, 13, 75, 77, 193 💬
170 Lisuride [1] LISURIDE[1] Lisuride 💬 [3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86 💬
171 Lixisenatide [1] Lixisenatide[1] Lixisenatide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
172 Lovastatin [1] LOVASTATIN[1] Lovastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
173 Lubiprostone [1] Lubiprostone[1] Lubiprostone 💬 [1] CLCN2 💬 [1] Mineral absorption 💬[5] 6, 13, 97, 290, 299 💬
174 LY3884961 [1] LY3884961---[2] 6, 19 💬
175 Magnesium [2] MAGNESIO; Magnesium---[23] 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬
176 Magnesium oxide [1] Magnesium oxide[1] Magnesium oxide 💬 --[4] 6, 113, 166, 291 💬
177 Maltodextrin [1] Maltodextrin[1] Maltodextrin 💬 --[4] 6, 13, 96, 97 💬
178 Mannitol [3] D-Mannitol; Mannite; Mannitol[1] Mannitol 💬 --[8] 6, 13, 21, 28, 60, 96, 113, 299 💬
179 Masitinib [2] MASITINIB; Masitinib mesylate[1] Masitinib 💬 [1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
180 Mavoglurant [1] Mavoglurant---[2] 6, 206 💬
181 MC-1 [1] MC-1---[4] 6, 13, 46, 49 💬
182 Medical Cannabis [1] Medical Cannabis[1] Cannabis 💬 --[3] 6, 96, 97 💬
183 Melatonin [1] Melatonin[1] Melatonin 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
184 Melevodopa [1] Melevodopa[1] Melevodopa 💬 --[1] 6 💬
185 Melperone [1] Melperone[2] Melperone ,
Melperone hydrochloride 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
186 Memantine [2] Memantine; MEMANTINE HYDROCHLORIDE[2] Memantine hydrochloride ,
Memantine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
187 Mesdopetam [1] Mesdopetam---[1] 6 💬
188 Metformin [4] Metformin; METFORMIN HYDROCHLORIDE; Metformina; Metformine[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
189 Methylphenidate [2] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE[2] Methylphenidate hydrochloride ,
Methylphenidate 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
190 Methylprednisolone [3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
191 Midazolam [1] Midazolam[3] Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
192 Midodrine [2] Midodrine; MIDODRINE HYDROCHLORIDE[2] Midodrine hydrochloride ,
Midodrine 💬 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58 💬
193 Minocycline [2] Minocycline; MINOCYCLINE HYDROCHLORIDE[2] Minocycline hydrochloride ,
Minocycline 💬 		--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
194 Minodronic acid [1] Minodronic acid---[4] 6, 46, 93, 95 💬
195 Minzasolmin [1] Minzasolmin[1] Minzasolmin 💬 [1] SNCA 💬 [3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 6 💬
196 Mirabegron [1] Mirabegron[1] Mirabegron 💬 [1] ADRB3 💬 [9] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
197 Mirtazapine [1] Mirtazapine[1] Mirtazapine 💬 [11] ADRA2A,
ADRA2B,
ADRA2C,
HTR2A,
HTR2B,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[9] Calcium signaling pathway, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬[4] 6, 85, 97, 156 💬
198 Moclobemide [1] MOCLOBEMIDE[1] Moclobemide 💬 [1] MAOA 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
199 Modafinil [1] Modafinil[1] Modafinil 💬 --[6] 6, 13, 49, 93, 96, 97 💬
200 Montelukast [2] Montelukast; MONTELUKAST SODIUM[2] Montelukast sodium ,
Montelukast 💬 		[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[10] 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
201 Moxifloxacin [2] Moxifloxacin; Moxifloxacin Hydrochloride[3] Moxifloxacin hydrochloride ,
Moxifloxacin ,
Moxifloxacin hydrochloride monohydrate 💬 		--[10] 2, 6, 46, 49, 85, 86, 113, 226, 240, 299 💬
202 Muscimol [1] Muscimol---[1] 6 💬
203 Nabilone [1] Nabilone[1] Nabilone 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[4] 6, 13, 97, 127 💬
204 Nadolol [1] Nadolol[1] Nadolol 💬 [2] ADRB1,
ADRB2 💬 		[13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
205 Naldemedine [1] Naldemedine[2] Naldemedine ,
Naldemedine tosylate 💬 		[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 6 💬
206 Nalmefene [1] Nalmefene[3] Nalmefene hydrochloride ,
Nalmefene ,
Nalmefene hydrochloride hydrate 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 93 💬
207 Naloxone [3] Naloxone; NALOXONE HYDROCHLORIDE; NALOXONE HYDROCHLORIDE DIHYDRATE[3] Naloxone hydrochloride ,
Naloxone ,
Naloxone hydrochloride dihydrate 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
208 Naltrexone [2] Naltrexone; Naltrexone Hydrochloride[2] Naltrexone hydrochloride ,
Naltrexone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
209 Nebicapone [1] Nebicapone---[1] 6 💬
210 Nelotanserin [1] Nelotanserin[1] Nelotanserin 💬 [1] HTR2A 💬 [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
211 Neridronic Acid [1] Neridronic Acid---[1] 6 💬
212 NeuroCell-PD [1] NeuroCell-PD---[1] 6 💬
213 Niacin [2] Niacin; Nicotinic acid[1] Niacin 💬 --[4] 6, 46, 79, 265 💬
214 Nicotinamide [2] Niacinamide; Nicotinamide[1] Niacinamide 💬 --[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
215 Nicotinamide riboside [2] Nicotinamide Riboside; Nicotinamide Riboside Chloride---[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
216 Nicotine [1] Nicotine[3] Nicotine ,
Nicotine bitartrate ,
Nicotine polacrilex 💬 		[16] CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬 		[9] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Ebolavirus, Lyssavirus and Morbillivirus 💬[3] 6, 13, 84 💬
217 Nilotinib [2] Nilotinib; NILOTINIB HYDROCHLORIDE MONOHYDRATE[1] Nilotinib 💬 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬 		[35] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86 💬
218 Nitisinone [1] NITISINONE[1] Nitisinone 💬 [1] HPD 💬 [3] Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬[3] 6, 164, 241 💬
219 Nitrogen [1] Nitrogen[1] Nitrogen 💬 --[6] 5, 6, 17, 171, 211, 299 💬
220 Nortriptyline [2] Nortriptyline; Nortriptyline hydrochloride[2] Nortriptyline hydrochloride ,
Nortriptyline 💬 		[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226 💬
221 Omeprazole [3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
222 Ondansetron [2] Ondansetron; Ondansetron hydrochloride dihydrate[2] Ondansetron ,
Ondansetron hydrochloride hydrate 💬 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 97, 98, 107, 231 💬
223 Opicapone [1] OPICAPONE[1] Opicapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6 💬
224 OSU-6162 [0] ---[2] 6, 8 💬
225 Oxybuprocaine [1] Oxybuprocaine[2] Benoxinate hydrochloride ,
Oxybuprocaine 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 6 💬
226 Oxybutynin [1] Oxybutynin[2] Oxybutynin ,
Oxybutynin chloride 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
227 Oxycodone [2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298 💬
228 Oxygen [1] Oxygen[1] Oxygen 💬 --[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
229 Oxytocin [1] Oxytocin[1] Oxytocin 💬 [1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[8] 6, 70, 72, 127, 168, 193, 206, 226 💬
230 Pardoprunox [2] Pardoprunox; Pardoprunox hydrochloride[2] Pardoprunox hydrochloride ,
Pardoprunox 💬 		[3] DRD2,
DRD3,
HTR1A 💬 		[12] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
231 Paroxetine [1] Paroxetine[4] Paroxetine hydrochloride hemihydrate ,
Paroxetine ,
Paroxetine hydrochloride ,
Paroxetine mesylate 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85 💬
232 Pentoxifylline [1] Pentoxifylline[1] Pentoxifylline 💬 --[13] 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
233 Perampanel [1] Perampanel[2] Perampanel ,
Perampanel hydrate 💬 		[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		[17] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144 💬
234 Pergolide [1] PERGOLIDE[2] Pergolide mesylate ,
Pergolide 💬 		[2] DRD1,
DRD2 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
235 Phenserine [1] Phenserine---[1] 6 💬
236 Piclozotan [1] Piclozotan---[1] 6 💬
237 Pilocarpine [2] Pilocarpine; Pilocarpine Hydrochloride[3] Pilocarpine ,
Pilocarpine hydrochloride ,
Pilocarpine nitrate 💬 		[2] CHRM2,
CHRM3 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299 💬
238 Pimavanserin [2] PIMAVANSERIN; PIMAVANSERIN TARTRATE[1] Pimavanserin tartrate 💬 [2] HTR2A,
HTR2C 💬 		[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
239 Pioglitazone [1] PIOGLITAZONE[2] Pioglitazone hydrochloride ,
Pioglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
240 Pirepemat [1] Pirepemat---[1] 6 💬
241 Piribedil [1] Piribedil[1] Piribedil 💬 [2] DRD2,
DRD3 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
242 Pitolisant [1] Pitolisant[2] Pitolisant ,
Pitolisant hydrochloride 💬 		[1] HRH3 💬 [2] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193 💬
243 Pittsburgh Compound B [2] C-11 PiB; Pittsburgh Compound B---[3] 6, 13, 127 💬
244 Polyethylene glycol [4] Macrogol; MACROGOL 3350; Polyethylene glycol; Polyethylene Glycol 3350[3] Polyethylene glycol 3350 ,
Macrogol 4000 ,
Macrogol 6000 💬 		--[8] 6, 50, 96, 97, 195, 235, 276, 299 💬
245 Posiphen [2] Buntanetap; Posiphen[1] Buntanetap 💬 [1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[1] 6 💬
246 Pramipexole [3] Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE[2] Pramipexole dihydrochloride ,
Pramipexole 💬 		[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 20, 74 💬
247 Prasinezumab [1] Prasinezumab[1] Prasinezumab 💬 [1] SNCA 💬 [3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 6 💬
248 Preladenant [1] Preladenant[1] Preladenant 💬 [1] ADORA2A 💬 [8] Alcoholism, Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
249 Pridopidine [2] Pridopidine; PRIDOPIDINE HYDROCHLORIDE[2] Pridopidine ,
Pridopidine hydrochloride 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8 💬
250 Promethazine [1] Promethazine[3] Promethazine hydrochloride ,
Promethazine ,
Promethazine teoclate 💬 		[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[2] 6, 96 💬
251 Propanoic acid [2] Propanoic acid; Sodium propionate[3] Propionic acid ,
Sodium propionate ,
Sodium propionate 💬 		--[3] 6, 97, 271 💬
252 Propofol [1] Propofol[1] Propofol 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
253 Propranolol [2] Propranolol; Propranolol Hydrochloride[2] Propranolol hydrochloride ,
Propranolol 💬 		[3] ADRB1,
ADRB2,
ADRB3 💬 		[14] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 158, 167, 215, 216, 227, 278 💬
254 Psilocybin [2] Psilocybin; Psilocybine[1] Psilocybin 💬 [1] HTR2A 💬 [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[5] 2, 6, 13, 149, 206 💬
255 Pyridostigmine [2] Pyridostigmine; PYRIDOSTIGMINE BROMIDE[1] Pyridostigmine bromide 💬 [1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[5] 3, 6, 11, 51, 256 💬
256 Quetiapine [1] Quetiapine[2] Quetiapine fumarate ,
Quetiapine 💬 		[2] DRD2,
HTR2A 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13 💬
257 Rabeprazole [1] Rabeprazole[2] Rabeprazole sodium ,
Rabeprazole 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[3] 2, 6, 51 💬
258 Raclopride [1] Raclopride---[4] 5, 6, 7, 17 💬
259 Radotinib [1] Radotinib---[1] 6 💬
260 Ramelteon [1] Ramelteon[1] Ramelteon 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46 💬
261 Rasagiline [2] Rasagiline; RASAGILINE MESYLATE[3] Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
262 Remifentanil [1] Remifentanil[2] Remifentanil hydrochloride ,
Remifentanil 💬 		[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[4] 6, 22, 70, 96 💬
263 Remimazolam [1] Remimazolam[2] Remimazolam besylate ,
Remimazolam 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 22, 97 💬
264 Repaglinide [1] Repaglinide[1] Repaglinide 💬 [2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
265 Resveratrol [2] Resveratrol; Trans-Resveratrol---[10] 2, 6, 8, 18, 46, 57, 89, 97, 113, 299 💬
266 Rifampin [2] RIFAMPICIN; Rifampin[2] Rifampin ,
Rifampicin sodium 💬 		--[5] 6, 13, 84, 86, 299 💬
267 Rifaximin [2] Rifaximin; RIFAXIMINA[1] Rifaximin 💬 --[8] 6, 65, 93, 96, 97, 99, 296, 299 💬
268 Rivastigmine [1] Rivastigmine[2] Rivastigmine tartrate ,
Rivastigmine 💬 		[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[3] 5, 6, 13 💬
269 Ropinirole [2] ROPINIROLE; Ropinirole Hydrochloride[2] Ropinirole hydrochloride ,
Ropinirole 💬 		[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 309 💬
270 Rosuvastatin [2] Rosuvastatin; Rosuvastatin calcium[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
271 Rotigotine [3] ROTIGOTINA; ROTIGOTINE; Rotigotine hydrochloride[1] Rotigotine 💬 [1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 67, 127 💬
272 Safinamide [2] Safinamida; SAFINAMIDE[2] Safinamide ,
Safinamide mesylate 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
273 Sage [1] Sage---[1] 6 💬
274 Saracatinib [1] Saracatinib[1] Saracatinib 💬 [2] ABL1,
SRC 💬 		[50] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Hormone signaling, Human cytomegalovirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[3] 6, 89, 272 💬
275 Sarcosine [1] Sarcosine---[1] 6 💬
276 Sargramostim [1] Sargramostim[1] Sargramostim 💬 [1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
277 Sarizotan [2] SARIZOTAN; Sarizotan Hydrochloride[1] Sarizotan hydrochloride 💬 [2] DRD2,
HTR1A 💬 		[12] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 156 💬
278 Selegiline [1] SELEGILINE[2] Selegiline hydrochloride ,
Selegiline 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
279 Semaglutide [1] Semaglutide[1] Semaglutide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 6, 51, 84, 113, 299 💬
280 Serine [2] L-Serine; Serine[1] Serine 💬 --[5] 2, 6, 86, 96, 222 💬
281 Sertraline [1] Sertraline[2] Sertraline hydrochloride ,
Sertraline 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 158, 206 💬
282 Sevoflurane [1] Sevoflurane[1] Sevoflurane 💬 --[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
283 Sildenafil [3] Sildenafil; Sildenafil citrate; SILDENAFILO[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
284 Silicon [1] Silicon---[1] 6 💬
285 Silodosin [1] Silodosin[1] Silodosin 💬 [1] ADRA1A 💬 [9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 6, 13 💬
286 Simvastatin [2] Simvastatin; Simvastatine[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
287 Sirolimus [2] Rapamycin; Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
288 Sitagliptin [1] Sitagliptin[3] Sitagliptin phosphate ,
Sitagliptin ,
Sitagliptin phosphate 💬 		[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[6] 6, 63, 75, 77, 233, 299 💬
289 Smilagenin [1] SMILAGENIN---[1] 6 💬
290 Sodium chloride [3] NaCl; SODIUM CHLORIDE; Sodium Chloride solution[1] Sodium chloride 💬 --[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
291 Sodium oxybate [1] Sodium Oxybate[1] Sodium oxybate 💬 --[2] 6, 149 💬
292 Solifenacin [2] Solifenacin; Solifenacin Succinate[2] Solifenacin succinate ,
Solifenacin 💬 		[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
293 Spheramine [1] Spheramine---[1] 6 💬
294 ST-36 [2] ST 36; ST36---[3] 6, 46, 49 💬
295 Sulforaphane [1] Sulforaphane---[2] 6, 205 💬
296 Sumanirole [1] Sumanirole---[1] 6 💬
297 Suvecaltamide [1] Suvecaltamide[1] Suvecaltamide 💬 [3] CACNA1G,
CACNA1H,
CACNA1I 💬 		[8] Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GnRH secretion, MAPK signaling pathway, Type II diabetes mellitus 💬[1] 6 💬
298 Suvorexant [1] Suvorexant[1] Suvorexant 💬 [2] HCRTR1,
HCRTR2 💬 		[2] Hormone signaling, Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13 💬
299 Tacrolimus [1] TACROLIMUS[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
300 Tadalafil [2] Tadalafil; TADALAFILO[1] Tadalafil 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[8] 6, 51, 75, 77, 84, 86, 113, 210 💬
301 TAK-071 [1] TAK-071---[1] 6 💬
302 Talampanel [1] Talampanel[1] Talampanel 💬 [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		[17] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6 💬
303 Tavapadon [2] PF-06649751; TAVAPADON[1] Tavapadon 💬 [2] DRD1,
DRD5 💬 		[12] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6 💬
304 Telmisartan [1] Telmisartan[1] Telmisartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 6, 57, 66, 67, 222 💬
305 Tenapanor [1] Tenapanor[2] Tenapanor ,
Tenapanor hydrochloride 💬 		[1] SLC9A3 💬 [4] Bile secretion, Mineral absorption, Protein digestion and absorption, Proximal tubule bicarbonate reclamation 💬[2] 6, 299 💬
306 Tenofovir [1] Tenofovir[1] Tenofovir 💬 --[8] 2, 6, 13, 25, 26, 93, 265, 325 💬
307 Tenofovir disoproxil [2] Tenofovir disoproxil; Tenofovir Disoproxil Fumarate[3] Tenofovir disoproxil fumarate ,
Tenofovir disoproxil phosphate ,
Tenofovir disoproxil maleate 💬 		--[3] 6, 93, 265 💬
308 Terazosin [2] Terazosin; Terazosin Hydrochloride[2] Terazosin hydrochloride ,
Terazosin 💬 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 6 💬
309 Tesofensine [2] Tesofensine; TESOFENSINE CITRATE---[2] 6, 193 💬
310 THK-5351 [1] THK-5351---[5] 5, 6, 7, 17, 127 💬
311 Tolcapone [2] Tolcapon; TOLCAPONE[1] Tolcapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[3] 6, 28, 127 💬
312 Topiramate [1] Topiramate[1] Topiramate 💬 [37] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[55] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Cadherin signaling, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, IgSF CAM signaling, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬
313 Tozadenant [1] TOZADENANT[1] Tozadenant 💬 [1] ADORA2A 💬 [8] Alcoholism, Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
314 Traxoprodil [1] Traxoprodil---[1] 6 💬
315 Trehalose [2] Cabaletta; Trehalose---[4] 2, 6, 18, 113 💬
316 Tributyrin [1] Tributyrin---[1] 6 💬
317 Trihexyphenidyl [1] Trihexyphenidyl[2] Trihexyphenidyl hydrochloride ,
Trihexyphenidyl 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6 💬
318 Trimethobenzamide [2] Trimethobenzamide; Trimethobenzamide Hydrochloride[2] Trimethobenzamide hydrochloride ,
Trimethobenzamide 💬 		--[1] 6 💬
319 Tropicamide [1] Tropicamide[1] Tropicamide 💬 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 6, 19 💬
320 Tryptophan [2] Propanoic acid; Tryptophan[1] Tryptophan 💬 --[3] 6, 46, 77 💬
321 Tulobuterol [2] Tulobuterol; TULOBUTEROL HYDROCHLORIDE[2] Tulobuterol hydrochloride ,
Tulobuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
322 Tyramine [1] Tyramine---[1] 6 💬
323 Tyrosine [4] Alanine; L-tyrosine; Propanoic acid; Tyrosine[1] Tyrosine 💬 --[4] 6, 75, 86, 111 💬
324 Ubiquinol [1] Ubiquinol---[4] 6, 8, 17, 57 💬
325 Ursodeoxycholic acid [3] UDCA; URSODEOXYCHOLIC ACID; Ursodiol[1] Ursodiol 💬 [1] NR1H4 💬 [1] Bile secretion 💬[10] 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
326 Valerian [1] Valerian---[1] 6 💬
327 Vancomycin [1] Vancomycin[2] Vancomycin ,
Vancomycin hydrochloride 💬 		--[9] 6, 13, 46, 70, 94, 96, 97, 296, 299 💬
328 Varenicline [2] Varenicline; VARENICLINE TARTRATE[2] Varenicline tartrate ,
Varenicline 💬 		[2] CHRNA4,
CHRNB2 💬 		[5] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[4] 6, 18, 53, 298 💬
329 Venglustat [2] Venglustat; Venglustat malate[2] Venglustat ,
Venglustat malate 💬 		[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[3] 6, 19, 67 💬
330 Venlafaxine [2] Venlafaxine; VENLAFAXINE HYDROCHLORIDE[3] Venlafaxine hydrochloride ,
Venlafaxine ,
Venlafaxine besylate monohydrate 💬 		[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 97 💬
331 Vildagliptin [1] Vildagliptin[1] Vildagliptin 💬 [1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[1] 6 💬
332 Vinpocetine [1] Vinpocetine[1] Vinpocetine 💬 --[1] 6 💬
333 Vitamin D [1] Vitamin D---[26] 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
334 Vitamin E [1] Vitamin E[1] Vitamin E 💬 --[12] 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
335 Vortioxetine [1] Vortioxetine[3] Vortioxetine ,
Vortioxetine hydrobromide ,
Vortioxetine hemihydrobromide 💬 		[7] HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬 		[6] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[2] 6, 127 💬
336 Vutiglabridin [1] Vutiglabridin---[1] 6 💬
337 Warfarin [3] Warfarin; Warfarin Potassium; Warfarin Sodium[3] Warfarin sodium ,
Warfarin potassium ,
Warfarin 💬 		[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
338 Water [1] Water[1] Water 💬 --[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬
339 Wheat [1] Wheat[1] Wheat 💬 --[5] 6, 53, 97, 98, 266 💬
340 Wheat bran [1] Wheat bran---[1] 6 💬
341 Whey [2] Whey; Whey protein---[4] 6, 46, 96, 97 💬
342 XP21279 [1] XP21279---[1] 6 💬
343 Yohimbine [1] Yohimbine[2] Yohimbine hydrochloride ,
Yohimbine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 6 💬
344 Zoledronic acid [2] ZOLEDRONIC ACID; ZOLEDRONIC ACID MONOHYDRATE[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
345 Zolmitriptan [1] ZOLMITRIPTAN[1] Zolmitriptan 💬 [2] HTR1B,
HTR1D 💬 		[5] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
346 Zolpidem [2] Zolpidem; Zolpidem Tartrate[2] Zolpidem tartrate ,
Zolpidem 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46 💬
347 Zonisamide [1] Zonisamide[1] Zonisamide 💬 [9] CACNA1G,
CACNA1H,
CACNA1I,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[13] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Cadherin signaling, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, IgSF CAM signaling, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus 💬[1] 6 💬
348 Zopiclone [1] Zopiclone[1] Zopiclone 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬