Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Barzolvolimab 💬[1] Barzolvolimab[1] Barzolvolimab[1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[1] 98 💬
2 Beclometasone 💬[1] Beclomethasone dipropionate[2] Beclometasone dipropionate; Beclomethasone dipropionate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 85, 97, 98 💬
3 Beclomethasone dipropionate 💬[1] Beclomethasone dipropionate[2] Beclometasone dipropionate; Beclomethasone dipropionate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 85, 97, 98 💬
4 Beclomethasone dipropionate monohydrate 💬[1] Beclomethasone dipropionate[2] Beclometasone dipropionate; Beclomethasone dipropionate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 85, 97, 98 💬
5 Benralizumab 💬[1] Benralizumab[1] Benralizumab[1] IL5RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[5] 44, 45, 98, 162, 299 💬
6 Bethanechol chloride 💬[1] Bethanechol[1] Bethanechol[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 98 💬
7 Budesonide 💬[1] Budesonide[1] Budesonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[7] 66, 93, 94, 95, 96, 97, 98 💬
8 Cefadroxil 💬[1] Cefadroxil[0] ---
9 Cefadroxil 💬[1] Cefadroxil[0] ---
10 Cendakimab 💬[1] Cendakimab[1] Cendakimab[1] IL13 💬 [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 98 💬
11 Cholecalciferol 💬[1] Cholecalciferol[4] Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[15] 6, 13, 19, 20, 34, 46, 49, 51, 53, 65, 96, 97, 228, 298, 299 💬
12 Citalopram 💬[1] Citalopram[1] Citalopram[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[5] 6, 13, 46, 98, 127 💬
13 Citalopram hydrobromide 💬[1] Citalopram[1] Citalopram[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[5] 6, 13, 46, 98, 127 💬
14 Dexlansoprazole 💬[1] Dexlansoprazole[1] Dexlansoprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[1] 98 💬
15 Dexlansoprazole sesquihydrate 💬[1] Dexlansoprazole[1] Dexlansoprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[1] 98 💬
16 Dupilumab 💬[1] Dupilumab[1] Dupilumab[1] IL4R 💬 [8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[5] 51, 97, 98, 160, 162 💬
17 Esomeprazole 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
18 Esomeprazole magnesium 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
19 Esomeprazole magnesium dihydrate 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
20 Esomeprazole sodium 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
21 Esomeprazole strontium 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
22 Etrasimod 💬[1] Etrasimod[1] Etrasimod[3] S1PR1,
S1PR4,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 96, 97, 98 💬
23 Etrasimod arginine 💬[1] Etrasimod[1] Etrasimod[3] S1PR1,
S1PR4,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 96, 97, 98 💬
24 Famotidine 💬[1] Famotidine[2] Famotidina; Famotidine[1] HRH2 💬 [4] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 98, 145, 300 💬
25 Fluticasone 💬[1] Fluticasone[1] Fluticasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 98, 228, 299 💬
26 Fluticasone propionate 💬[1] Fluticasone propionate[1] Fluticasone propionate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 98, 228, 306 💬
27 Formaldehyde 💬[1] Formaldehyde[0] ---
28 Honey 💬[1] Honey[1] Honey--[3] 57, 98, 230 💬
29 Hydrocortisone 💬[1] Hydrocortisone[3] Cortisol; Hydrocortisone; Hydrocortisonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[8] 41, 53, 75, 78, 81, 83, 97, 299 💬
30 Infliximab 💬[1] Infliximab[1] Infliximab[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[24] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 164, 269, 270, 271 💬
31 Lirentelimab 💬[1] Lirentelimab[1] Lirentelimab--[1] 98 💬
32 Loratadine 💬[1] Loratadine[1] Loratadine[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 13, 19, 46, 89, 98 💬
33 Losartan 💬[1] Losartan[2] Losartan; Losartan potassium[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
34 Losartan potassium 💬[1] Losartan[2] Losartan; Losartan potassium[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
35 Mepolizumab 💬[1] Mepolizumab[1] Mepolizumab[1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[4] 44, 45, 98, 162 💬
36 Mesalamine 💬[1] Mesalazine[6] 5-aminosalicylic acid; 5-ASA; Mesalamine; Mesalazina; Mesalazine; Mesalazinum--[4] 46, 96, 97, 164 💬
37 Mometasone 💬[1] Mometasone[0] [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬-
38 Mometasone furoate 💬[1] Mometasone furoate[1] Mometasone furoate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 98, 162 💬
39 Mometasone furoate hydrate 💬[1] Mometasone furoate[1] Mometasone furoate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 98, 162 💬
40 Montelukast 💬[1] Montelukast[2] Montelukast; Montelukast sodium[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[9] 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
41 Montelukast sodium 💬[1] Montelukast[2] Montelukast; Montelukast sodium[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[9] 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
42 Omalizumab 💬[1] Omalizumab[1] Omalizumab[1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
43 Omeprazole 💬[1] Omeprazole[3] Omeprazol; Omeprazole; Omeprazole magnesium[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[14] 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
44 Omeprazole magnesium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; Omeprazole magnesium[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[14] 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
45 Omeprazole sodium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; Omeprazole magnesium[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[14] 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
46 Ondansetron 💬[1] Ondansetron[2] Ondansetron; Ondansetron hydrochloride dihydrate[5] HTR3,
HTR3,
HTR3,
HTR3,
HTR3 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 97, 98, 107, 231 💬
47 Ondansetron hydrochloride hydrate 💬[1] Ondansetron[2] Ondansetron; Ondansetron hydrochloride dihydrate[5] HTR3,
HTR3,
HTR3,
HTR3,
HTR3 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 97, 98, 107, 231 💬
48 Propofol 💬[1] Propofol[1] Propofol[16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
49 Reslizumab 💬[1] Reslizumab[1] Reslizumab[1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 98 💬
50 Sevoflurane 💬[1] Sevoflurane[1] Sevoflurane--[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
51 Sirolimus 💬[1] Sirolimus[2] Rapamycin; Sirolimus[1] MTOR 💬 [49] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[44] 2, 6, 13, 15, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
52 Solrikitug 💬[1] Solrikitug[0] [1] TSLPR 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬-
53 Sucralfate 💬[1] Sucralfate[1] Sucralfate--[1] 98 💬
54 Tezepelumab 💬[1] Tezepelumab[3] AMG 157; MEDI9929; Tezepelumab[1] TSLP 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[3] 44, 45, 98 💬
55 Vonoprazan 💬[1] Vonoprazan[1] Vonoprazan[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[3] 63, 97, 98 💬
56 Xanthan gum 💬[1] Xanthan gum[1] Xanthan GUM--[1] 98 💬