Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Arginine [1] Arginine[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬
--[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
2 Barium [1] Barium---[5] 2, 6, 19, 97, 98 💬
3 Barzolvolimab [1] Barzolvolimab[1] Barzolvolimab 💬 [1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[1] 98 💬
4 Beclomethasone dipropionate [2] BECLOMETASONE DIPROPIONATE; Beclomethasone dipropionate[3] Beclomethasone dipropionate ,
Beclometasone ,
Beclomethasone dipropionate monohydrate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 97, 98 💬
5 Benralizumab [1] Benralizumab[1] Benralizumab 💬 [1] IL5RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[5] 44, 45, 98, 162, 299 💬
6 Bethanechol [1] Bethanechol[1] Bethanechol chloride 💬 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 98 💬
7 Budesonide [1] Budesonide[1] Budesonide 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
8 CALY-002 [1] CALY-002---[1] 98 💬
9 Cendakimab [1] Cendakimab[1] Cendakimab 💬 [1] IL13 💬 [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 98 💬
10 Citalopram [1] Citalopram[2] Citalopram hydrobromide ,
Citalopram 💬
[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
11 Dexlansoprazole [2] Dexlansoprazole; Lansoprazole[2] Dexlansoprazole ,
Dexlansoprazole sesquihydrate 💬
[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[1] 98 💬
12 Dupilumab [1] Dupilumab[1] Dupilumab 💬 [1] IL4R 💬 [8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[8] 51, 97, 98, 160, 162, 222, 300, 306 💬
13 Esomeprazole [3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[5] Esomeprazole magnesium ,
Esomeprazole sodium ,
Esomeprazole ,
Esomeprazole strontium ,
Esomeprazole magnesium dihydrate 💬
[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
14 Etrasimod [1] Etrasimod[2] Etrasimod ,
Etrasimod arginine 💬
[3] S1PR1,
S1PR4,
S1PR5 💬
[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 96, 97, 98 💬
15 Famotidine [1] Famotidine[1] Famotidine 💬 [1] HRH2 💬 [4] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[7] 6, 46, 86, 98, 107, 145, 300 💬
16 Fluticasone [1] Fluticasone[1] Fluticasone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[4] 98, 228, 299, 306 💬
17 Fluticasone propionate [1] FLUTICASONE PROPIONATE[1] Fluticasone propionate 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 98, 228, 306 💬
18 Gold [1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
19 Honey [1] Honey[1] Honey 💬 --[4] 57, 63, 98, 230 💬
20 Infliximab [2] Infliximab; Infliximab-Dyyb[1] Infliximab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 223, 269, 270, 271 💬
21 L-arginine [1] L-arginine---[10] 2, 21, 46, 67, 96, 97, 98, 113, 223, 299 💬
22 Lansoprazole [1] Lansoprazole[1] Lansoprazole 💬 [2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[8] 63, 71, 85, 98, 166, 222, 223, 299 💬
23 Lirentelimab [1] Lirentelimab[1] Lirentelimab 💬 --[1] 98 💬
24 Loratadine [1] LORATADINE[1] Loratadine 💬 [1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 13, 19, 46, 89, 98 💬
25 Losartan [2] Losartan; LOSARTAN POTASSIUM[2] Losartan potassium ,
Losartan 💬
[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
26 Mepolizumab [1] MEPOLIZUMAB[1] Mepolizumab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[4] 44, 45, 98, 162 💬
27 Mometasone [1] Mometasone[1] Mometasone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 98, 162 💬
28 Mometasone furoate [1] Mometasone furoate[2] Mometasone furoate ,
Mometasone furoate hydrate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 98, 162 💬
29 Montelukast [2] Montelukast; MONTELUKAST SODIUM[2] Montelukast sodium ,
Montelukast 💬
[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[10] 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
30 NDX-3315 [1] NDX-3315---[1] 98 💬
31 Nitric Oxide [1] Nitric Oxide[1] Nitric oxide 💬 --[12] 46, 51, 85, 86, 88, 97, 98, 210, 251, 294, 299, 340 💬
32 Omalizumab [1] Omalizumab[1] Omalizumab 💬 [1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
33 Omeprazole [3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬
[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
34 Ondansetron [2] Ondansetron; Ondansetron hydrochloride dihydrate[2] Ondansetron ,
Ondansetron hydrochloride hydrate 💬
[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬
[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 97, 98, 107, 231 💬
35 Potassium [1] Potassium[1] Potassium 💬 --[17] 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬
36 Propofol [1] Propofol[1] Propofol 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
37 Reslizumab [1] Reslizumab[1] Reslizumab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 98 💬
38 Sevoflurane [1] Sevoflurane[1] Sevoflurane 💬 --[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
39 Sirolimus [2] Rapamycin; Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
40 Solrikitug [1] Solrikitug[1] Solrikitug 💬 [1] CRLF2 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 98 💬
41 Sucralfate [1] Sucralfate[1] Sucralfate 💬 --[1] 98 💬
42 Tezepelumab [2] AMG 157; Tezepelumab[1] Tezepelumab 💬 [1] TSLP 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[3] 44, 45, 98 💬
43 Upadacitinib [1] UPADACITINIB[3] Upadacitinib ,
Upadacitinib tartrate ,
Upadacitinib hydrate 💬
[1] JAK1 💬 [27] Coronavirus disease, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[12] 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
44 Vitamin D [1] Vitamin D---[26] 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
45 Vonoprazan [1] Vonoprazan[1] Vonoprazan 💬 [2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[3] 63, 97, 98 💬
46 Wheat [1] Wheat[1] Wheat 💬 --[5] 6, 53, 97, 98, 266 💬
47 Xanthan gum [1] Xanthan gum[1] Xanthan gum 💬 --[1] 98 💬
48 Xylose [1] Xylose[1] Xylose 💬 --[1] 98 💬