Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 GABBR1 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
2 GABBR2 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
3 HTR1D 💬 [5] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
4 HTR1D 💬 [5] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
5 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
6 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
7 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Psilocybin 💬 Psilocybin [5] 2, 6, 13, 149, 206 💬
8 HTR2C 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
9 HTR2C 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
10 IL1R1 💬 [13] MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Th17 cell differentiation, Inflammatory mediator regulation of TRP channels, Pathogenic Escherichia coli infection, Shigellosis, Amoebiasis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra [22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
11 IL1R2 💬 [7] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Amoebiasis, Human T-cell leukemia virus 1 infection, Transcriptional misregulation in cancer, Prostate cancer, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra [22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
12 IL6R 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, HIF-1 signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th17 cell differentiation, Non-alcoholic fatty liver disease, Human cytomegalovirus infection, Coronavirus disease, Pathways in cancer Tocilizumab 💬 Tocilizumab [26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
13 MTNR1A 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
14 MTNR1B 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
15 NPC1L1 💬 [1] Fat digestion and absorption Ezetimibe 💬 Ezetimibe [5] 49, 79, 93, 149, 260 💬
16 SCN3A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
17 SCN9A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
18 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
19 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
20 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
21 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
22 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Incobotulinumtoxin A 💬 Botulinum toxin type A [13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
23 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A [13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
24 SV2A 💬 [1] ECM-receptor interaction Levetiracetam 💬 Levetiracetam [7] 2, 4, 6, 13, 34, 149, 307 💬
25 SV2A 💬 [1] ECM-receptor interaction Brivaracetam 💬 Brivaracetam [2] 149, 309 💬
26 SV2A 💬 [1] ECM-receptor interaction Padsevonil 💬 Padsevonil [1] 149 💬
27 SV2B 💬 [1] ECM-receptor interaction Padsevonil 💬 Padsevonil [1] 149 💬
28 SV2C 💬 [1] ECM-receptor interaction Padsevonil 💬 Padsevonil [1] 149 💬