Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 C1R 💬 [6] Phagosome, Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Conestat alfa 💬 Conestat alfa [1] 61 💬
2 C1S 💬 [5] Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Sutimlimab 💬 Sutimlimab [1] 61 💬
3 C1S 💬 [5] Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Conestat alfa 💬 Conestat alfa [1] 61 💬
4 C3 💬 [17] Neuroactive ligand-receptor interaction, Phagosome, Complement and coagulation cascades, Neutrophil extracellular trap formation, Alcoholic liver disease, Shigellosis, Pertussis, Legionellosis, Leishmaniasis, Chagas disease, Staphylococcus aureus infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Viral carcinogenesis, Systemic lupus erythematosus Pegcetacoplan 💬 Pegcetacoplan [4] 2, 61, 62, 222 💬
5 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Zilucoplan 💬 Zilucoplan [3] 2, 11, 62 💬
6 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
7 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Crovalimab 💬 Crovalimab [2] 62, 109 💬
8 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
9 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Pozelimab 💬 Pozelimab [2] 11, 62 💬
10 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
11 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Ravulizumab 💬 Ravulizumab [7] 2, 11, 13, 50, 62, 66, 109 💬
12 C5AR1 💬 [6] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Alcoholic liver disease, Staphylococcus aureus infection, Coronavirus disease - COVID-19 Avacopan 💬 Avacopan [3] 43, 44, 222 💬
13 CA1 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
14 CA1 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
15 CA1 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
16 CA12 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
17 CA12 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
18 CA12 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
19 CA13 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
20 CA13 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
21 CA13 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
22 CA14 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
23 CA14 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
24 CA14 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
25 CA2 💬 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide 💬 Dorzolamide [1] 90 💬
26 CA2 💬 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
27 CA2 💬 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
28 CA2 💬 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dichlorphenamide 💬 Diclofenamide [1] 114 💬
29 CA3 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
30 CA3 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
31 CA3 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
32 CA4 💬 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
33 CA4 💬 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation Dorzolamide 💬 Dorzolamide [1] 90 💬
34 CA4 💬 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation Dichlorphenamide 💬 Diclofenamide [1] 114 💬
35 CA4 💬 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
36 CA5A 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
37 CA5A 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
38 CA5A 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
39 CA5B 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
40 CA5B 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
41 CA5B 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
42 CA6 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
43 CA6 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
44 CA6 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
45 CA7 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
46 CA7 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
47 CA7 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
48 CA8 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
49 CA8 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
50 CA8 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
51 CA9 💬 [2] Nitrogen metabolism, Metabolic pathways Dichlorphenamide 💬 Diclofenamide [1] 114 💬
52 CA9 💬 [2] Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
53 CA9 💬 [2] Nitrogen metabolism, Metabolic pathways Dorzolamide 💬 Dorzolamide [1] 90 💬
54 CACNA1B 💬 [15] MAPK signaling pathway, Calcium signaling pathway, Synaptic vesicle cycle, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Type II diabetes mellitus, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Morphine addiction, Nicotine addiction, Chemical carcinogenesis - receptor activation Cilnidipine 💬 Cilnidipine [1] 67 💬
55 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
56 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
57 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
58 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Propiverine 💬 Propiverine [1] 226 💬
59 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
60 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Perhexiline 💬 Perhexiline [2] 58, 272 💬
61 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nifedipine 💬 Nifedipine [2] 50, 81 💬
62 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nicardipine 💬 Nicardipine [2] 70, 86 💬
63 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Cilnidipine 💬 Cilnidipine [1] 67 💬
64 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
65 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
66 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Cilnidipine 💬 Cilnidipine [1] 67 💬
67 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
68 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
69 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
70 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
71 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Perhexiline 💬 Perhexiline [2] 58, 272 💬
72 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Propiverine 💬 Propiverine [1] 226 💬
73 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
74 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nifedipine 💬 Nifedipine [2] 50, 81 💬
75 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nicardipine 💬 Nicardipine [2] 70, 86 💬
76 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
77 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
78 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nicardipine 💬 Nicardipine [2] 70, 86 💬
79 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Propiverine 💬 Propiverine [1] 226 💬
80 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
81 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
82 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nifedipine 💬 Nifedipine [2] 50, 81 💬
83 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
84 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Cilnidipine 💬 Cilnidipine [1] 67 💬
85 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
86 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
87 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Perhexiline 💬 Perhexiline [2] 58, 272 💬
88 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Zonisamide 💬 Zonisamide [1] 6 💬
89 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Flunarizine 💬 Flunarizine [1] 149 💬
90 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
91 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Zonisamide 💬 Zonisamide [1] 6 💬
92 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Flunarizine 💬 Flunarizine [1] 149 💬
93 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
94 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Zonisamide 💬 Zonisamide [1] 6 💬
95 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Flunarizine 💬 Flunarizine [1] 149 💬
96 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
97 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
98 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
99 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
100 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
101 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nifedipine 💬 Nifedipine [2] 50, 81 💬
102 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Propiverine 💬 Propiverine [1] 226 💬
103 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Perhexiline 💬 Perhexiline [2] 58, 272 💬
104 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
105 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nicardipine 💬 Nicardipine [2] 70, 86 💬
106 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
107 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Cilnidipine 💬 Cilnidipine [1] 67 💬
108 CACNA2D1 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Mirogabalin 💬 Mirogabalin [1] 70 💬
109 CACNA2D1 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
110 CACNA2D1 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
111 CACNA2D2 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
112 CACNA2D2 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Mirogabalin 💬 Mirogabalin [1] 70 💬
113 CACNA2D2 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
114 CACNA2D3 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
115 CACNA2D3 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
116 CACNA2D4 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
117 CACNA2D4 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
118 CALCA 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction Fremanezumab 💬 Fremanezumab [2] 124, 226 💬
119 CASP9 💬 [35] Platinum drug resistance, p53 signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Apoptosis - multiple species, VEGF signaling pathway, Thyroid hormone signaling pathway, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Legionellosis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Small cell lung cancer, Non-small cell lung cancer, Viral myocarditis, Lipid and atherosclerosis Rimiducid 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
120 CASR 💬 [2] NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action Cinacalcet 💬 Cinacalcet [1] 238 💬
121 CCKBR 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gastric acid secretion Proglumide 💬 Proglumide [1] 298 💬
122 CCL2 💬 [17] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, NOD-like receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Yersinia infection, Chagas disease, Malaria, Human cytomegalovirus infection, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Rheumatoid arthritis, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
123 CCN2 💬 [2] Apelin signaling pathway, Hippo signaling pathway Pamrevlumab 💬 Pamrevlumab [2] 85, 113 💬
124 CCR2 💬 [3] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway Cenicriviroc 💬 Cenicriviroc [1] 94 💬
125 CCR4 💬 [5] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Viral carcinogenesis Mogamulizumab 💬 Mogamulizumab [1] 26 💬
126 CCR5 💬 [11] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Endocytosis, Toxoplasmosis, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis Maraviroc 💬 Maraviroc [2] 46, 84 💬
127 CCR5 💬 [11] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Endocytosis, Toxoplasmosis, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis Cenicriviroc 💬 Cenicriviroc [1] 94 💬
128 CD19 💬 [5] PI3K-Akt signaling pathway, Hematopoietic cell lineage, B cell receptor signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Obexelimab 💬 Obexelimab [1] 300 💬
129 CD19 💬 [5] PI3K-Akt signaling pathway, Hematopoietic cell lineage, B cell receptor signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Inebilizumab 💬 Inebilizumab [4] 11, 13, 51, 300 💬
130 CD22 💬 [3] Cell adhesion molecules, Hematopoietic cell lineage, B cell receptor signaling pathway Epratuzumab 💬 Epratuzumab [1] 49 💬
131 CD274 💬 [2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer Durvalumab 💬 Durvalumab [1] 85 💬
132 CD274 💬 [2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer Atezolizumab 💬 Atezolizumab [1] 85 💬
133 CD38 💬 [7] Nicotinate and nicotinamide metabolism, Metabolic pathways, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Daratumumab 💬 Daratumumab [5] 13, 28, 48, 49, 63 💬
134 CD38 💬 [7] Nicotinate and nicotinamide metabolism, Metabolic pathways, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Isatuximab 💬 Isatuximab [3] 28, 61, 283 💬
135 CD38 💬 [7] Nicotinate and nicotinamide metabolism, Metabolic pathways, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Mezagitamab 💬 Mezagitamab [2] 63, 66 💬
136 CD3D 💬 [11] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Visilizumab 💬 Visilizumab [2] 96, 97 💬
137 CD3D 💬 [11] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Otelixizumab 💬 Otelixizumab [1] 46 💬
138 CD3E 💬 [11] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Mosunetuzumab 💬 Mosunetuzumab [1] 49 💬
139 CD3E 💬 [11] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Visilizumab 💬 Visilizumab [2] 96, 97 💬
140 CD3E 💬 [11] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Otelixizumab 💬 Otelixizumab [1] 46 💬
141 CD3G 💬 [10] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer Otelixizumab 💬 Otelixizumab [1] 46 💬
142 CD3G 💬 [10] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer Visilizumab 💬 Visilizumab [2] 96, 97 💬
143 CD4 💬 [14] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Cytokine-cytokine receptor interaction, Cell adhesion molecules, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Yersinia infection, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Zanolimumab 💬 Zanolimumab [1] 46 💬
144 CD40 💬 [17] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Transcriptional misregulation in cancer, Asthma, Autoimmune thyroid disease, Systemic lupus erythematosus, Allograft rejection, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis Bleselumab 💬 Bleselumab [1] 222 💬
145 CD40 💬 [17] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Transcriptional misregulation in cancer, Asthma, Autoimmune thyroid disease, Systemic lupus erythematosus, Allograft rejection, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
146 CD40 💬 [17] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Transcriptional misregulation in cancer, Asthma, Autoimmune thyroid disease, Systemic lupus erythematosus, Allograft rejection, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis Iscalimab 💬 Iscalimab [2] 49, 53 💬
147 CD40LG 💬 [14] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecules, T cell receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Asthma, Autoimmune thyroid disease, Systemic lupus erythematosus, Allograft rejection, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis Toralizumab 💬 Toralizumab [1] 63 💬
148 CD52 💬 - Alemtuzumab 💬 Alemtuzumab [22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
149 CD58 💬 [2] Cell adhesion molecules, Epstein-Barr virus infection Alefacept 💬 Alefacept [6] 37, 60, 65, 164, 284, 285 💬
150 CD6 💬 [1] Cell adhesion molecules Itolizumab 💬 Itolizumab [1] 49 💬
151 CD74 💬 [3] Antigen processing and presentation, Tuberculosis, Herpes simplex virus 1 infection Milatuzumab 💬 Milatuzumab [1] 49 💬
152 CD80 💬 [11] Virion - Adenovirus, Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
153 CD80 💬 [11] Virion - Adenovirus, Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Belatacept 💬 Belatacept [1] 46 💬
154 CD86 💬 [13] Virion - Adenovirus, Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Transcriptional misregulation in cancer, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
155 CD86 💬 [13] Virion - Adenovirus, Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Transcriptional misregulation in cancer, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Belatacept 💬 Belatacept [1] 46 💬
156 CDK4 💬 [28] Endocrine resistance, Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Tight junction, T cell receptor signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Hepatitis C, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, Glioma, Melanoma, Bladder cancer, Chronic myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma Abemaciclib 💬 Abemaciclib [1] 34 💬
157 CDK6 💬 [23] Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Cushing syndrome, Hepatitis C, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, MicroRNAs in cancer, Pancreatic cancer, Glioma, Melanoma, Chronic myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma Abemaciclib 💬 Abemaciclib [1] 34 💬
158 CETP 💬 [1] Cholesterol metabolism Anacetrapib 💬 Anacetrapib [1] 79 💬
159 CFB 💬 [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 Iptacopan 💬 Iptacopan [5] 61, 62, 66, 109, 222 💬
160 CFD 💬 [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 Danicopan 💬 Danicopan [1] 62 💬
161 CFTR 💬 [8] ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Lumacaftor 💬 Lumacaftor [1] 299 💬
162 CFTR 💬 [8] ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Deutivacaftor 💬 Deutivacaftor [1] 299 💬
163 CFTR 💬 [8] ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Tezacaftor 💬 Tezacaftor [1] 299 💬
164 CFTR 💬 [8] ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Elexacaftor 💬 Elexacaftor [1] 299 💬
165 CFTR 💬 [8] ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Ivacaftor 💬 Ivacaftor [1] 299 💬
166 CFTR 💬 [8] ABC transporters, cAMP signaling pathway, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Galicaftor 💬 Galicaftor [1] 299 💬
167 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
168 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Propiverine 💬 Propiverine [1] 226 💬
169 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine [1] 2 💬
170 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
171 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine [1] 254 💬
172 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine [2] 2, 299 💬
173 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide [1] 6 💬
174 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Blarcamesine 💬 Blarcamesine [1] 156 💬
175 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Tropicamide 💬 Tropicamide [1] 6 💬
176 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Pilocarpine 💬 Pilocarpine [3] 6, 53, 299 💬
177 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
178 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Blarcamesine 💬 Blarcamesine [1] 156 💬
179 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Chlorpromazine 💬 Chlorpromazine [1] 254 💬
180 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Atropine 💬 Atropine [2] 2, 299 💬
181 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Scopolamine 💬 Scopolamine [1] 2 💬
182 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Propiverine 💬 Propiverine [1] 226 💬
183 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Fesoterodine 💬 Fesoterodine [1] 6 💬
184 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
185 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Propiverine 💬 Propiverine [1] 226 💬
186 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
187 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine [1] 254 💬
188 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine [1] 2 💬
189 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Blarcamesine 💬 Blarcamesine [1] 156 💬
190 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Cevimeline 💬 Cevimeline [1] 53 💬
191 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tolterodine 💬 Tolterodine [2] 17, 53 💬
192 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Solifenacin 💬 Solifenacin [3] 6, 13, 53 💬
193 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Darifenacin 💬 Darifenacin [2] 6, 13 💬
194 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide [1] 6 💬
195 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Pilocarpine 💬 Pilocarpine [3] 6, 53, 299 💬
196 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Fesoterodine 💬 Fesoterodine [1] 6 💬
197 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
198 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine [2] 2, 299 💬
199 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Tropicamide 💬 Tropicamide [1] 6 💬
200 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Propiverine 💬 Propiverine [1] 226 💬
201 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Atropine 💬 Atropine [2] 2, 299 💬
202 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
203 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Blarcamesine 💬 Blarcamesine [1] 156 💬
204 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Scopolamine 💬 Scopolamine [1] 2 💬
205 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
206 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Chlorpromazine 💬 Chlorpromazine [1] 254 💬
207 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Propiverine 💬 Propiverine [1] 226 💬
208 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Blarcamesine 💬 Blarcamesine [1] 156 💬
209 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine [1] 2 💬
210 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
211 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide [1] 6 💬
212 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine [1] 254 💬
213 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine [2] 2, 299 💬
214 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
215 CHRNA1 💬 [2] Virion - Lyssavirus, Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
216 CHRNA10 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
217 CHRNA2 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
218 CHRNA3 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
219 CHRNA4 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline [3] 6, 18, 53 💬
220 CHRNA4 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
221 CHRNA5 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
222 CHRNA6 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
223 CHRNA7 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Nicotine addiction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
224 CHRNA9 💬 [2] Neuroactive ligand-receptor interaction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
225 CHRNB1 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
226 CHRNB2 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
227 CHRNB2 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline [3] 6, 18, 53 💬
228 CHRNB3 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
229 CHRNB4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
230 CHRND 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
231 CHRNE 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
232 CHRNG 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
233 CLCN2 💬 [1] Mineral absorption Lubiprostone 💬 Lubiprostone [4] 6, 13, 290, 299 💬
234 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Rimonabant 💬 Rimonabant [1] 193 💬
235 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Cannabidiol 💬 Cannabidiol [20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
236 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Dronabinol 💬 Dronabinol [8] 2, 8, 13, 36, 46, 96, 271, 298 💬
237 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Nabilone 💬 Nabilone [3] 6, 13, 127 💬
238 CNR2 💬 [1] Neuroactive ligand-receptor interaction Nabilone 💬 Nabilone [3] 6, 13, 127 💬
239 CNR2 💬 [1] Neuroactive ligand-receptor interaction Lenabasum 💬 Ajulemic acid [3] 50, 51, 299 💬
240 CNR2 💬 [1] Neuroactive ligand-receptor interaction Dronabinol 💬 Dronabinol [8] 2, 8, 13, 36, 46, 96, 271, 298 💬
241 CNR2 💬 [1] Neuroactive ligand-receptor interaction Cannabidiol 💬 Cannabidiol [20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
242 COMT 💬 [4] Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Entacapone 💬 Entacapone [2] 6, 17 💬
243 COMT 💬 [4] Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Opicapone 💬 Opicapone [1] 6 💬
244 COMT 💬 [4] Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Tolcapone 💬 Tolcapone [3] 6, 28, 127 💬
245 CPS1 💬 [6] Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, Metabolic pathways, Carbon metabolism, Biosynthesis of amino acids Carglumic acid 💬 Carglumic acid [3] 245, 246, 251 💬
246 CPT1A 💬 [9] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, Thermogenesis, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Alcoholic liver disease Perhexiline 💬 Perhexiline [2] 58, 272 💬
247 CPT1B 💬 [10] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, Thermogenesis, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Alcoholic liver disease, Diabetic cardiomyopathy Perhexiline 💬 Perhexiline [2] 58, 272 💬
248 CPT1C 💬 [8] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, Thermogenesis, Adipocytokine signaling pathway, Glucagon signaling pathway, Alcoholic liver disease Perhexiline 💬 Perhexiline [2] 58, 272 💬
249 CPT2 💬 [5] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, Thermogenesis, Diabetic cardiomyopathy Perhexiline 💬 Perhexiline [2] 58, 272 💬
250 CRHR1 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Long-term depression, Cushing syndrome Corticorelin ovine triflutate 💬 Corticorelin ovine triflutate [1] 75 💬
251 CRHR1 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Long-term depression, Cushing syndrome Corticorelin 💬 Corticorelin [1] 75 💬
252 CRHR2 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Cushing syndrome Corticorelin 💬 Corticorelin [1] 75 💬
253 CRHR2 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Cushing syndrome Corticorelin ovine triflutate 💬 Corticorelin ovine triflutate [1] 75 💬
254 CSF1R 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Sunitinib 💬 Sunitinib [2] 28, 34 💬
255 CSF1R 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Pexidartinib 💬 Pexidartinib [1] 34 💬
256 CSF2 💬 [16] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Shigellosis, Amoebiasis, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Coronavirus disease - COVID-19, Transcriptional misregulation in cancer, Acute myeloid leukemia, Rheumatoid arthritis Otilimab 💬 Otilimab [1] 46 💬
257 CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Mavrilimumab 💬 Mavrilimumab [2] 41, 46 💬
258 CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Sargramostim 💬 Sargramostim [7] 6, 28, 60, 62, 96, 229, 285 💬
259 CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Molgramostim 💬 Molgramostim [3] 97, 229, 299 💬
260 CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Regramostim 💬 Regramostim [1] 229 💬
261 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Pegfilgrastim 💬 Pegfilgrastim [1] 60 💬
262 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Filgrastim 💬 Filgrastim [35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
263 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Lenograstim 💬 Lenograstim [7] 2, 13, 16, 18, 19, 57, 65 💬
264 CTLA4 💬 [4] Cell adhesion molecules, T cell receptor signaling pathway, Autoimmune thyroid disease, Rheumatoid arthritis Tremelimumab 💬 Tremelimumab [1] 96 💬
265 CTLA4 💬 [4] Cell adhesion molecules, T cell receptor signaling pathway, Autoimmune thyroid disease, Rheumatoid arthritis Ipilimumab 💬 Ipilimumab [1] 159 💬
266 CTSC 💬 [2] Lysosome, Apoptosis Brensocatib 💬 Brensocatib [1] 299 💬
267 CXCR1 💬 [6] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Phospholipase D signaling pathway, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection Reparixin 💬 Reparixin [2] 298, 299 💬
268 CXCR2 💬 [7] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Phospholipase D signaling pathway, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection Reparixin 💬 Reparixin [2] 298, 299 💬
269 CXCR4 💬 [14] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Endocytosis, Axon guidance, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
270 CYP11A1 💬 [6] Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole [1] 75 💬
271 CYP11B1 💬 [4] Steroid hormone biosynthesis, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole [1] 75 💬
272 CYP11B1 💬 [4] Steroid hormone biosynthesis, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome Metyrapone 💬 Metyrapone [1] 75 💬
273 CYP11B2 💬 [3] Steroid hormone biosynthesis, Metabolic pathways, Aldosterone synthesis and secretion Osilodrostat 💬 Osilodrostat [1] 75 💬
274 CYP17A1 💬 [6] Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Ketoconazole 💬 Ketoconazole [3] 8, 13, 75 💬
275 CYP17A1 💬 [6] Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole [1] 75 💬
276 CYP19A1 💬 [3] Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis Letrozole 💬 Letrozole [2] 81, 89 💬
277 CYP19A1 💬 [3] Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis Anastrozole 💬 Anastrozole [3] 78, 86, 193 💬
278 CYP46A1 💬 [1] Primary bile acid biosynthesis Soticlestat 💬 Soticlestat [2] 140, 144 💬
279 CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction Montelukast 💬 Montelukast [8] 6, 13, 46, 61, 63, 85, 98, 228 💬
280 CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction Tipelukast 💬 Tipelukast [1] 85 💬
281 CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction Ibudilast 💬 Ibudilast [2] 2, 13 💬