Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 S1PR1 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
2 S1PR1 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
3 S1PR1 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Siponimod 💬 Siponimod [2] 13, 50 💬
4 S1PR1 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Fingolimod 💬 Fingolimod [3] 13, 14, 156 💬
5 S1PR1 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ponesimod 💬 Ponesimod [1] 13 💬
6 S1PR1 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
7 S1PR1 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Cenerimod 💬 Cenerimod [1] 49 💬
8 S1PR2 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
9 S1PR2 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
10 S1PR2 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
11 S1PR3 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
12 S1PR3 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
13 S1PR3 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
14 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
15 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
16 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
17 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
18 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
19 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
20 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Siponimod 💬 Siponimod [2] 13, 50 💬
21 SCN1A 💬 [1] Dopaminergic synapse Cifenline 💬 Cibenzoline [1] 58 💬
22 SCN1A 💬 [1] Dopaminergic synapse Levobupivacaine 💬 Levobupivacaine [1] 46 💬
23 SCN1A 💬 [1] Dopaminergic synapse Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
24 SCN1A 💬 [1] Dopaminergic synapse Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
25 SCN1A 💬 [1] Dopaminergic synapse Zonisamide 💬 Zonisamide [1] 6 💬
26 SCN1A 💬 [1] Dopaminergic synapse Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
27 SCN1A 💬 [1] Dopaminergic synapse Rufinamide 💬 Rufinamide [1] 144 💬
28 SCN1A 💬 [1] Dopaminergic synapse Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
29 SCN1A 💬 [1] Dopaminergic synapse Flecainide 💬 Flecainide [1] 6 💬
30 SCN1A 💬 [1] Dopaminergic synapse Phenytoin 💬 Phenytoin [1] 13 💬
31 SCN1A 💬 [1] Dopaminergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
32 SCN1A 💬 [1] Dopaminergic synapse Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
33 SCN1A 💬 [1] Dopaminergic synapse Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
34 SCN1A 💬 [1] Dopaminergic synapse Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
35 SCN1A 💬 [1] Dopaminergic synapse Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
36 SCN1A 💬 [1] Dopaminergic synapse Quinidine 💬 Quinidine [3] 2, 8, 13 💬
37 SCN1A 💬 [1] Dopaminergic synapse Amiodarone 💬 Amiodarone [2] 28, 127 💬
38 SCN1A 💬 [1] Dopaminergic synapse Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
39 SCN1A 💬 [1] Dopaminergic synapse Eleclazine 💬 Eleclazine [1] 58 💬
40 SCN2A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
41 SCN2A 💬 [1] Taste transduction Levobupivacaine 💬 Levobupivacaine [1] 46 💬
42 SCN2A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
43 SCN2A 💬 [1] Taste transduction Eleclazine 💬 Eleclazine [1] 58 💬
44 SCN2A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
45 SCN2A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
46 SCN2A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
47 SCN2A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
48 SCN2A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
49 SCN2A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
50 SCN2A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
51 SCN2A 💬 [1] Taste transduction Amiodarone 💬 Amiodarone [2] 28, 127 💬
52 SCN2A 💬 [1] Taste transduction Cifenline 💬 Cibenzoline [1] 58 💬
53 SCN2A 💬 [1] Taste transduction Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
54 SCN2A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
55 SCN2A 💬 [1] Taste transduction Phenytoin 💬 Phenytoin [1] 13 💬
56 SCN2A 💬 [1] Taste transduction Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
57 SCN2A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
58 SCN2A 💬 [1] Taste transduction Rufinamide 💬 Rufinamide [1] 144 💬
59 SCN3A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
60 SCN3A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
61 SCN3A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
62 SCN3A 💬 [1] Taste transduction Phenytoin 💬 Phenytoin [1] 13 💬
63 SCN3A 💬 [1] Taste transduction Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
64 SCN3A 💬 [1] Taste transduction Levobupivacaine 💬 Levobupivacaine [1] 46 💬
65 SCN3A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
66 SCN3A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
67 SCN3A 💬 [1] Taste transduction Amiodarone 💬 Amiodarone [2] 28, 127 💬
68 SCN3A 💬 [1] Taste transduction Eleclazine 💬 Eleclazine [1] 58 💬
69 SCN3A 💬 [1] Taste transduction Cifenline 💬 Cibenzoline [1] 58 💬
70 SCN3A 💬 [1] Taste transduction Rufinamide 💬 Rufinamide [1] 144 💬
71 SCN3A 💬 [1] Taste transduction Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
72 SCN3A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
73 SCN3A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
74 SCN3A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
75 SCN3A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
76 SCN3A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
77 SCN3A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
78 SCN3A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
79 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Flecainide 💬 Flecainide [1] 6 💬
80 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
81 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
82 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
83 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
84 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
85 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
86 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Rufinamide 💬 Rufinamide [1] 144 💬
87 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
88 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Zonisamide 💬 Zonisamide [1] 6 💬
89 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Eleclazine 💬 Eleclazine [1] 58 💬
90 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
91 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Cifenline 💬 Cibenzoline [1] 58 💬
92 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Phenytoin 💬 Phenytoin [1] 13 💬
93 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Amiodarone 💬 Amiodarone [2] 28, 127 💬
94 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Levobupivacaine 💬 Levobupivacaine [1] 46 💬
95 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Quinidine 💬 Quinidine [3] 2, 8, 13 💬
96 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
97 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
98 SCN9A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
99 SCN9A 💬 [1] Taste transduction Cifenline 💬 Cibenzoline [1] 58 💬
100 SCN9A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
101 SCN9A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
102 SCN9A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
103 SCN9A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
104 SCN9A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
105 SCN9A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
106 SCN9A 💬 [1] Taste transduction Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
107 SCN9A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
108 SCN9A 💬 [1] Taste transduction Amiodarone 💬 Amiodarone [2] 28, 127 💬
109 SCN9A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
110 SCN9A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
111 SCN9A 💬 [1] Taste transduction Phenytoin 💬 Phenytoin [1] 13 💬
112 SCN9A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
113 SCN9A 💬 [1] Taste transduction Eleclazine 💬 Eleclazine [1] 58 💬
114 SCN9A 💬 [1] Taste transduction Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
115 SCN9A 💬 [1] Taste transduction Rufinamide 💬 Rufinamide [1] 144 💬
116 SCN9A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
117 SCN9A 💬 [1] Taste transduction Levobupivacaine 💬 Levobupivacaine [1] 46 💬
118 SCNN1A 💬 [2] Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
119 SCNN1B 💬 [2] Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
120 SCNN1G 💬 [2] Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
121 SERPINC1 💬 [1] Complement and coagulation cascades Adomiparin 💬 Enoxaparin [1] 46 💬
122 SERPINC1 💬 [1] Complement and coagulation cascades Sulodexide 💬 Sulodexide [2] 51, 271 💬
123 SERPINC1 💬 [1] Complement and coagulation cascades Adomiparin 💬 Heparin [11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬
124 SERPINC1 💬 [1] Complement and coagulation cascades Adomiparin 💬 Parnaparin [1] 97 💬
125 SERPIND1 💬 [1] Complement and coagulation cascades Sulodexide 💬 Sulodexide [2] 51, 271 💬
126 SIGLEC8 💬 - Lirentelimab 💬 Lirentelimab [1] 98 💬
127 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Blarcamesine 💬 Blarcamesine [1] 156 💬
128 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan 💬 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
129 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
130 SLAMF7 💬 - Elotuzumab 💬 Elotuzumab [1] 28 💬
131 SLC10A1 💬 [2] Bile secretion, Hepatitis B Maralixibat 💬 Maralixibat [3] 296, 297, 338 💬
132 SLC10A2 💬 [1] Bile secretion Odevixibat 💬 Odevixibat [3] 296, 297, 338 💬
133 SLC10A2 💬 [1] Bile secretion Maralixibat 💬 Maralixibat [3] 296, 297, 338 💬
134 SLC10A2 💬 [1] Bile secretion Elobixibat 💬 Elobixibat [1] 6 💬
135 SLC12A2 💬 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection Bumetanide 💬 Bumetanide [2] 6, 158 💬
136 SLC12A2 💬 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection Furosemide 💬 Furosemide [2] 6, 86 💬
137 SLC12A3 💬 - Indapamide 💬 Indapamide [1] 13 💬
138 SLC12A3 💬 - Chlorothiazide 💬 Chlorothiazide [1] 225 💬
139 SLC12A3 💬 - Bendroflumethiazide 💬 Bendroflumethiazide [1] 67 💬
140 SLC12A3 💬 - Hydrochlorothiazide 💬 Hydrochlorothiazide [4] 13, 67, 225, 235 💬
141 SLC18A2 💬 [7] Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Tetrabenazine 💬 Tetrabenazine [1] 8 💬
142 SLC18A2 💬 [7] Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Deutetrabenazine 💬 Deutetrabenazine [1] 8 💬
143 SLC18A2 💬 [7] Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Valbenazine 💬 Valbenazine [1] 8 💬
144 SLC22A12 💬 - Benzbromarone 💬 Benzbromarone [1] 86 💬
145 SLC5A2 💬 - Empagliflozin 💬 Empagliflozin [6] 58, 65, 67, 72, 97, 257 💬
146 SLC5A2 💬 - Dapagliflozin 💬 Dapagliflozin [7] 19, 49, 66, 67, 86, 88, 222 💬
147 SLC6A1 💬 [2] Synaptic vesicle cycle, GABAergic synapse Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
148 SLC6A2 💬 [1] Synaptic vesicle cycle Doxepin 💬 Doxepin [1] 6 💬
149 SLC6A2 💬 [1] Synaptic vesicle cycle Bupropion 💬 Bupropion [5] 8, 18, 21, 96, 171 💬
150 SLC6A2 💬 [1] Synaptic vesicle cycle Phentermine 💬 Phentermine [1] 97 💬
151 SLC6A2 💬 [1] Synaptic vesicle cycle Amoxapine 💬 Amoxapine [1] 46 💬
152 SLC6A2 💬 [1] Synaptic vesicle cycle Desipramine 💬 Desipramine [2] 120, 156 💬
153 SLC6A2 💬 [1] Synaptic vesicle cycle Venlafaxine 💬 Venlafaxine [3] 6, 13, 46 💬
154 SLC6A2 💬 [1] Synaptic vesicle cycle Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
155 SLC6A2 💬 [1] Synaptic vesicle cycle Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
156 SLC6A2 💬 [1] Synaptic vesicle cycle Amitriptyline 💬 Amitriptyline [4] 78, 97, 226, 299 💬
157 SLC6A2 💬 [1] Synaptic vesicle cycle Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
158 SLC6A2 💬 [1] Synaptic vesicle cycle Milnacipran 💬 Milnacipran [2] 46, 49 💬
159 SLC6A2 💬 [1] Synaptic vesicle cycle Atomoxetine 💬 Atomoxetine [4] 6, 8, 13, 17 💬
160 SLC6A2 💬 [1] Synaptic vesicle cycle Duloxetine 💬 Duloxetine [2] 6, 13 💬
161 SLC6A2 💬 [1] Synaptic vesicle cycle Nortriptyline 💬 Nortriptyline [2] 6, 226 💬
162 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
163 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion [5] 8, 18, 21, 96, 171 💬
164 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
165 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Armodafinil 💬 Armodafinil [3] 6, 13, 84 💬
166 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
167 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
168 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Trazodone 💬 Trazodone [1] 2 💬
169 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Paroxetine 💬 Paroxetine [4] 6, 13, 46, 85 💬
170 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Vortioxetine 💬 Vortioxetine [1] 6 💬
171 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Venlafaxine 💬 Venlafaxine [3] 6, 13, 46 💬
172 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Desipramine 💬 Desipramine [2] 120, 156 💬
173 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Amitriptyline 💬 Amitriptyline [4] 78, 97, 226, 299 💬
174 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Citalopram 💬 Citalopram [7] 6, 8, 13, 18, 46, 98, 127 💬
175 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
176 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Amoxapine 💬 Amoxapine [1] 46 💬
177 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
178 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Sertraline 💬 Sertraline [2] 6, 206 💬
179 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Milnacipran 💬 Milnacipran [2] 46, 49 💬
180 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Doxepin 💬 Doxepin [1] 6 💬
181 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Nortriptyline 💬 Nortriptyline [2] 6, 226 💬
182 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Duloxetine 💬 Duloxetine [2] 6, 13 💬
183 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Escitalopram 💬 Escitalopram [4] 2, 6, 13, 46 💬
184 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Phentermine 💬 Phentermine [1] 97 💬
185 SMAD7 💬 [2] TGF-beta signaling pathway, Hippo signaling pathway Mongersen 💬 Mongersen [2] 96, 97 💬
186 SMN1 💬 - Onasemnogene abeparvovec 💬 Onasemnogene abeparvovec [1] 3 💬
187 SMN2 💬 [1] Nucleocytoplasmic transport Risdiplam 💬 Risdiplam [1] 3 💬
188 SMN2 💬 - Branaplam 💬 Branaplam [2] 3, 8 💬
189 SMN2 💬 - Nusinersen 💬 Nusinersen [1] 3 💬
190 SMO 💬 [5] Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma Taladegib 💬 Taladegib [1] 85 💬
191 SMO 💬 [5] Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma Vismodegib 💬 Vismodegib [1] 85 💬
192 SMPD1 💬 [5] Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, Lysosome, Necroptosis Olipudase alfa 💬 Olipudase alfa [1] 19 💬
193 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Rimabotulinumtoxin B 💬 Botulinum toxin type B [4] 2, 6, 13, 51 💬
194 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A [14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
195 SNCA 💬 [3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Prasinezumab 💬 Prasinezumab [1] 6 💬
196 SOD1 💬 [8] Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species Tofersen 💬 Tofersen [1] 2 💬
197 SORT1 💬 [3] Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab [2] 2, 127 💬
198 SOST 💬 [2] Wnt signaling pathway, Parathyroid hormone synthesis, secretion and action Romosozumab 💬 Romosozumab [1] 274 💬
199 SRC 💬 [42] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Dasatinib 💬 Dasatinib [2] 51, 85 💬
200 SRC 💬 [42] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Dasatinib 💬 Dasatinib [2] 51, 85 💬
201 SRC 💬 [42] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Bosutinib 💬 Bosutinib [2] 2, 67 💬
202 SRC 💬 [42] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Saracatinib 💬 Saracatinib [3] 6, 89, 272 💬
203 SRD5A1 💬 [2] Steroid hormone biosynthesis, Metabolic pathways Dutasteride 💬 Dutasteride [2] 1, 2 💬
204 SRD5A2 💬 [3] Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer Dutasteride 💬 Dutasteride [2] 1, 2 💬
205 SRD5A2 💬 [3] Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer Finasteride 💬 Finasteride [1] 6 💬
206 SSTR1 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Somatostatin 💬 Somatostatin [2] 67, 78 💬
207 SSTR1 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
208 SSTR2 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
209 SSTR2 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion Somatostatin 💬 Somatostatin [2] 67, 78 💬
210 SSTR2 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion Octreotide 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
211 SSTR3 💬 [2] Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
212 SSTR3 💬 [2] Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Somatostatin 💬 Somatostatin [2] 67, 78 💬
213 SSTR4 💬 [1] Neuroactive ligand-receptor interaction Somatostatin 💬 Somatostatin [2] 67, 78 💬
214 SSTR5 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
215 SSTR5 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action Somatostatin 💬 Somatostatin [2] 67, 78 💬
216 SV2A 💬 [1] ECM-receptor interaction Padsevonil 💬 Padsevonil [1] 149 💬
217 SV2A 💬 [1] ECM-receptor interaction Brivaracetam 💬 Brivaracetam [2] 149, 309 💬
218 SV2A 💬 [1] ECM-receptor interaction Levetiracetam 💬 Levetiracetam [5] 2, 4, 6, 13, 307 💬
219 SV2B 💬 [1] ECM-receptor interaction Padsevonil 💬 Padsevonil [1] 149 💬
220 SV2C 💬 [1] ECM-receptor interaction Padsevonil 💬 Padsevonil [1] 149 💬
221 SYK 💬 [17] NF-kappa B signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Osteoclast differentiation, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease - COVID-19, Viral carcinogenesis Fostamatinib 💬 Fostamatinib [4] 46, 49, 61, 66 💬