Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naloxone 💬 Naloxone [2] 6, 226 💬
2 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalmefene 💬 Nalmefene [2] 6, 93 💬
3 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naloxone hydrochloride dihydrate 💬 Naloxone [2] 6, 226 💬
4 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naloxone hydrochloride 💬 Naloxone [2] 6, 226 💬
5 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone terephthalate 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
6 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone hydrochloride 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
7 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalbuphine 💬 Nalbuphine [1] 85 💬
8 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
9 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
10 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
11 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide 💬 Loperamide [2] 13, 97 💬
12 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalmefene hydrochloride 💬 Nalmefene [2] 6, 93 💬
13 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
14 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalmefene hydrochloride hydrate 💬 Nalmefene [2] 6, 93 💬
15 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone hydrochloride 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
16 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalmefene hydrochloride 💬 Nalmefene [2] 6, 93 💬
17 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
18 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Trimebutine maleate 💬 Trimebutine [1] 51 💬
19 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone terephthalate 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
20 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Buprenorphine hydrochloride 💬 Buprenorphine [3] 46, 70, 298 💬
21 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone hydrochloride 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
22 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naloxone 💬 Naloxone [2] 6, 226 💬
23 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalmefene 💬 Nalmefene [2] 6, 93 💬
24 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Buprenorphine 💬 Buprenorphine [3] 46, 70, 298 💬
25 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dezocine 💬 Dezocine [1] 46 💬
26 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naloxone hydrochloride 💬 Naloxone [2] 6, 226 💬
27 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide 💬 Loperamide [2] 13, 97 💬
28 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
29 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone hydrochloride 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
30 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
31 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Trimebutine 💬 Trimebutine [1] 51 💬
32 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
33 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalbuphine 💬 Nalbuphine [1] 85 💬
34 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Nalmefene hydrochloride hydrate 💬 Nalmefene [2] 6, 93 💬
35 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naloxone hydrochloride dihydrate 💬 Naloxone [2] 6, 226 💬
36 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Loperamide 💬 Loperamide [2] 13, 97 💬
37 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Trimebutine maleate 💬 Trimebutine [1] 51 💬
38 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Hydromorphone 💬 Hydromorphone [1] 70 💬
39 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naloxone hydrochloride dihydrate 💬 Naloxone [2] 6, 226 💬
40 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine hydrochloride hydrate 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
41 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl citrate 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
42 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Sufentanil 💬 Sufentanil [4] 11, 22, 70, 280 💬
43 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naloxone hydrochloride 💬 Naloxone [2] 6, 226 💬
44 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Dihydrocodeine bitartrate 💬 Dihydrocodeine [1] 310 💬
45 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine tartrate 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
46 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naltrexone hydrochloride 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
47 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Remifentanil hydrochloride 💬 Remifentanil [3] 6, 22, 70 💬
48 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Methadone 💬 Methadone [1] 60 💬
49 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
50 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Tramadol hydrochloride 💬 Tramadol [4] 46, 70, 226, 271 💬
51 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Oxycodone hydrochloride 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
52 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Nalbuphine 💬 Nalbuphine [1] 85 💬
53 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Buprenorphine 💬 Buprenorphine [3] 46, 70, 298 💬
54 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Dihydrocodeine 💬 Dihydrocodeine [1] 310 💬
55 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
56 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Hydromorphone hydrochloride 💬 Hydromorphone [1] 70 💬
57 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Dihydrocodeine phosphate 💬 Dihydrocodeine [1] 310 💬
58 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
59 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Meperidine hydrochloride 💬 Meperidine [2] 97, 298 💬
60 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Nalmefene hydrochloride 💬 Nalmefene [2] 6, 93 💬
61 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Nalmefene 💬 Nalmefene [2] 6, 93 💬
62 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl hydrochloride 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
63 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Dezocine 💬 Dezocine [1] 46 💬
64 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naltrexone 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
65 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
66 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Tramadol 💬 Tramadol [4] 46, 70, 226, 271 💬
67 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Trimebutine 💬 Trimebutine [1] 51 💬
68 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Nalmefene hydrochloride hydrate 💬 Nalmefene [2] 6, 93 💬
69 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Remifentanil 💬 Remifentanil [3] 6, 22, 70 💬
70 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naloxone 💬 Naloxone [2] 6, 226 💬
71 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Dihydrocodeine thiocyanate 💬 Dihydrocodeine [1] 310 💬
72 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Buprenorphine hydrochloride 💬 Buprenorphine [3] 46, 70, 298 💬
73 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Oxycodone terephthalate 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
74 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Methadone hydrochloride 💬 Methadone [1] 60 💬
75 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Pethidine 💬 Meperidine [2] 97, 298 💬
76 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine sulfate 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
77 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Sufentanil citrate 💬 Sufentanil [4] 11, 22, 70, 280 💬
78 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Oxycodone 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
79 OSMR 💬 [3] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway Vixarelimab 💬 Vixarelimab [3] 51, 85, 97 💬
80 OXTR 💬 [5] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Oxytocin signaling pathway Carbetocin 💬 Carbetocin [1] 193 💬
81 OXTR 💬 [5] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Oxytocin signaling pathway Atosiban acetate 💬 Atosiban [1] 118 💬
82 OXTR 💬 [5] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Oxytocin signaling pathway Atosiban 💬 Atosiban [1] 118 💬
83 OXTR 💬 [5] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Oxytocin signaling pathway Oxytocin 💬 Oxytocin [8] 6, 70, 72, 127, 168, 193, 206, 226 💬