Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ANGPTL3 💬 [1] Cholesterol metabolism Evinacumab 💬 Evinacumab [1] 79 💬
2 APOB 💬 [4] Fat digestion and absorption, Vitamin digestion and absorption, Cholesterol metabolism, Lipid and atherosclerosis Mipomersen sodium 💬 Mipomersen [1] 79 💬
3 APOC3 💬 [2] PPAR signaling pathway, Cholesterol metabolism Volanesorsen 💬 Volanesorsen [1] 265 💬
4 APOC3 💬 [2] PPAR signaling pathway, Cholesterol metabolism Volanesorsen sodium 💬 Volanesorsen [1] 265 💬
5 CETP 💬 [1] Cholesterol metabolism Torcetrapib 💬 Torcetrapib [1] 79 💬
6 CETP 💬 [1] Cholesterol metabolism Obicetrapib 💬 Obicetrapib [1] 79 💬
7 CETP 💬 [1] Cholesterol metabolism Anacetrapib 💬 Anacetrapib [1] 79 💬
8 LIPA 💬 [4] Steroid biosynthesis, Lysosome biogenesis, Efferocytosis, Cholesterol metabolism Sebelipase alfa 💬 Sebelipase alfa [1] 19 💬
9 LIPC 💬 [2] Glycerolipid metabolism, Cholesterol metabolism Dextran sulfate sodium 💬 Dextran [5] 2, 62, 79, 96, 97 💬
10 LPL 💬 [4] Glycerolipid metabolism, PPAR signaling pathway, Cholesterol metabolism, Alzheimer disease Dextran sulfate sodium 💬 Dextran [5] 2, 62, 79, 96, 97 💬
11 PCSK9 💬 [1] Cholesterol metabolism Evolocumab 💬 Evolocumab [2] 79, 222 💬
12 PCSK9 💬 [1] Cholesterol metabolism Lerodalcibep 💬 Lerodalcibep [1] 79 💬
13 PCSK9 💬 [1] Cholesterol metabolism Inclisiran 💬 Inclisiran [1] 79 💬
14 PCSK9 💬 [1] Cholesterol metabolism Bococizumab 💬 Bococizumab [1] 79 💬
15 PCSK9 💬 [1] Cholesterol metabolism Alirocumab 💬 Alirocumab [1] 79 💬
16 PCSK9 💬 [1] Cholesterol metabolism Inclisiran sodium 💬 Inclisiran [1] 79 💬
17 SORT1 💬 [3] Lysosome biogenesis, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab [1] 127 💬