Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 cGMP-PKG signaling pathway 💬
 [2] ADORA1, ADORA3 💬 Adenosine 💬 Adenosine [4] 13, 57, 58, 65 💬
2 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
3 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
4 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
5 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
6 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
7 cGMP-PKG signaling pathway 💬
 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
8 cGMP-PKG signaling pathway 💬
 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine citrate 💬 Caffeine [8]  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
9 cGMP-PKG signaling pathway 💬
 [1] ADORA3 💬 Piclidenoson 💬 Piclidenoson [2] 46, 348 💬
10 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin hydrochloride 💬 Alfuzosin [1] 13 💬
11 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
12 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
13 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin mesylate 💬 Doxazosin [2] 57, 67 💬
14 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
15 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ifenprodil tartrate 💬 Ifenprodil [1] 13 💬
16 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ifenprodil 💬 Ifenprodil [1] 13 💬
17 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine hydrochloride 💬 Midodrine [3]  6 , 17, 58 💬
18 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
19 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
20 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
21 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine hydrochloride 💬 Phenylephrine [1] 22 💬
22 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
23 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine bitartrate 💬 Phenylephrine [1] 22 💬
24 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin hydrochloride 💬 Tamsulosin [1] 13 💬
25 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
26 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin hydrochloride 💬 Terazosin [1]  6  💬
27 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
28 cGMP-PKG signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 Ergoloid mesylates 💬 Ergoloid mesylate [1] 206 💬
29 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Dipivefrin hydrochloride 💬 Dipivefrin [1]  6  💬
30 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
31 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
32 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine [1] 11 💬
33 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Ephedrine hydrochloride 💬 Ephedrine [1] 11 💬
34 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Ephedrine sulfate 💬 Ephedrine [1] 11 💬
35 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
36 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
37 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
38 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
39 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Norepinephrine bitartrate 💬 Norepinephrine [2] 22, 296 💬
40 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Norepinephrine hydrochoride 💬 Norepinephrine [2] 22, 296 💬
41 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine hydrochloride 💬 Pseudoephedrine [1] 17 💬
42 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine polistirex 💬 Pseudoephedrine [1] 17 💬
43 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine sulfate 💬 Pseudoephedrine [1] 17 💬
44 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
45 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol [7]  6 , 46, 57, 58, 86, 113, 210 💬
46 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol phosphate 💬 Carvedilol [7]  6 , 46, 57, 58, 86, 113, 210 💬
47 cGMP-PKG signaling pathway 💬
 [8] ADRA1A, ADRA1B, ADRA1D, ADRB1, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol [1]  8  💬
48 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 Amiodarone hydrochloride 💬 Amiodarone [3] 28, 67, 127 💬
49 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 Amiodarone 💬 Amiodarone [3] 28, 67, 127 💬
50 cGMP-PKG signaling pathway 💬
 [1] ADRA2A 💬 Guanfacine hydrochloride 💬 Guanfacine [1] 193 💬
51 cGMP-PKG signaling pathway 💬
 [1] ADRA2A 💬 Guanfacine 💬 Guanfacine [1] 193 💬
52 cGMP-PKG signaling pathway 💬
 [1] ADRA2A 💬 Pimozide 💬 Pimozide [1]  2  💬
53 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Apraclonidine hydrochloride 💬 Apraclonidine [1] 11 💬
54 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Apraclonidine 💬 Apraclonidine [1] 11 💬
55 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Brimonidine tartrate 💬 Brimonidine [2] 13, 90 💬
56 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Brimonidine 💬 Brimonidine [2] 13, 90 💬
57 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Chlorpromazine 💬 Chlorpromazine [2] 120, 254 💬
58 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [2] 120, 254 💬
59 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Clonidine 💬 Clonidine [3]  6 , 65, 70 💬
60 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Clonidine hydrochloride 💬 Clonidine [3]  6 , 65, 70 💬
61 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Clozapine 💬 Clozapine [1]  6  💬
62 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Dexmedetomidine 💬 Dexmedetomidine [15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
63 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Dexmedetomidine hydrochloride 💬 Dexmedetomidine [15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
64 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Guanabenz acetate 💬 Guanabenz [2]  2 , 13 💬
65 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Guanabenz 💬 Guanabenz [2]  2 , 13 💬
66 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Mirtazapine 💬 Mirtazapine [4]  6 , 85, 97, 156 💬
67 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Rilmenidine 💬 Rilmenidine [1]  8  💬
68 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Tizanidine hydrochloride 💬 Tizanidine [1] 13 💬
69 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Tizanidine 💬 Tizanidine [1] 13 💬
70 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Yohimbine hydrochloride 💬 Yohimbine [1]  6  💬
71 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 Yohimbine 💬 Yohimbine [1]  6  💬
72 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Atenolol 💬 Atenolol [1] 167 💬
73 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Bisoprolol fumarate 💬 Bisoprolol [5] 57, 58, 67, 86, 113 💬
74 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [5] 57, 58, 67, 86, 113 💬
75 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Celiprolol hydrochloride 💬 Celiprolol [1] 168 💬
76 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Celiprolol 💬 Celiprolol [1] 168 💬
77 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Dobutamine hydrochloride 💬 Dobutamine [5] 28, 57, 58, 86, 215 💬
78 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Dobutamine 💬 Dobutamine [5] 28, 57, 58, 86, 215 💬
79 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Dobutamine tartrate 💬 Dobutamine [5] 28, 57, 58, 86, 215 💬
80 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Metoprolol tartrate 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
81 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Metoprolol succinate 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
82 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Metoprolol 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
83 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Metoprolol fumarate 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
84 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Nebivolol 💬 Nebivolol [4] 17, 85, 113, 167 💬
85 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Nebivolol hydrochloride 💬 Nebivolol [4] 17, 85, 113, 167 💬
86 cGMP-PKG signaling pathway 💬
 [2] ADRB1, ADRB2 💬 Nadolol 💬 Nadolol [1]  6  💬
87 cGMP-PKG signaling pathway 💬
 [2] ADRB1, ADRB2 💬 Timolol 💬 Timolol [2] 157, 227 💬
88 cGMP-PKG signaling pathway 💬
 [2] ADRB1, ADRB2 💬 Timolol maleate 💬 Timolol [2] 157, 227 💬
89 cGMP-PKG signaling pathway 💬
 [2] ADRB1, ADRB2 💬 Timolol 💬 Timolol [2] 157, 227 💬
90 cGMP-PKG signaling pathway 💬
 [3] ADRB1, ADRB2, ADRB3 💬 Propranolol hydrochloride 💬 Propranolol [7]  6 , 158, 167, 215, 216, 227, 278 💬
91 cGMP-PKG signaling pathway 💬
 [3] ADRB1, ADRB2, ADRB3 💬 Propranolol 💬 Propranolol [7]  6 , 158, 167, 215, 216, 227, 278 💬
92 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [9] 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
93 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [9] 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
94 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Clenbuterol hydrochloride 💬 Clenbuterol [6]  1 ,  2 ,  6 , 57, 113, 256 💬
95 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Clenbuterol 💬 Clenbuterol [6]  1 ,  2 ,  6 , 57, 113, 256 💬
96 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Formoterol fumarate 💬 Formoterol [4] 85, 228, 299, 306 💬
97 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [4] 85, 228, 299, 306 💬
98 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Isoxsuprine hydrochloride 💬 Isoxsuprine [1] 13 💬
99 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Isoxsuprine 💬 Isoxsuprine [1] 13 💬
100 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Salmeterol xinafoate 💬 Salmeterol [1] 299 💬
101 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
102 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Terbutaline sulfate 💬 Terbutaline [2] 63, 118 💬
103 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Terbutaline 💬 Terbutaline [2] 63, 118 💬
104 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Tulobuterol hydrochloride 💬 Tulobuterol [1]  6  💬
105 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Tulobuterol 💬 Tulobuterol [1]  6  💬
106 cGMP-PKG signaling pathway 💬
 [1] ADRB3 💬 Mirabegron 💬 Mirabegron [4]  6 , 13, 53, 226 💬
107 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Angiotensin II 💬 Angiotensin II [2] 66, 222 💬
108 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Angiotensin II 💬 Angiotensin II [2] 66, 222 💬
109 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II [2] 66, 222 💬
110 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Azilsartan 💬 Azilsartan [1] 66 💬
111 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Buloxibutid 💬 Buloxibutid [1] 85 💬
112 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid [1] 85 💬
113 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [4] 57, 58, 67, 222 💬
114 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Irbesartan 💬 Irbesartan [6] 57, 66, 167, 168, 222, 223 💬
115 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Losartan potassium 💬 Losartan [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
116 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
117 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Olmesartan medoxomil 💬 Olmesartan [2] 57, 223 💬
118 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Olmesartan 💬 Olmesartan [2] 57, 223 💬
119 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [5]  6 , 57, 66, 67, 222 💬
120 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Valsartan 💬 Valsartan [11] 28, 57, 58, 66, 75, 86, 210, 218, 222, 223, 224 💬
121 cGMP-PKG signaling pathway 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [4] 66, 218, 222, 223 💬
122 cGMP-PKG signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
123 cGMP-PKG signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digoxin 💬 Digoxin [7]  2 ,  8 , 46, 57, 65, 67, 210 💬
124 cGMP-PKG signaling pathway 💬
 [1] BDKRB2 💬 Deucrictibant 💬 Deucrictibant [1] 65 💬
125 cGMP-PKG signaling pathway 💬
 [1] BDKRB2 💬 Icatibant acetate 💬 Icatibant [1] 65 💬
126 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
127 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
128 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
129 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
130 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Benidipine hydrochloride 💬 Benidipine [1] 57 💬
131 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Benidipine 💬 Benidipine [1] 57 💬
132 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
133 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem [4] 51, 58, 86, 88 💬
134 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem [4] 51, 58, 86, 88 💬
135 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem [4] 51, 58, 86, 88 💬
136 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine [1]  6  💬
137 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine [2] 70, 86 💬
138 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬
139 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬
140 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬
141 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline [2] 58, 272 💬
142 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
143 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine [1] 226 💬
144 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine [1] 226 💬
145 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
146 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil [5] 57, 58, 96, 140, 167 💬
147 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil [5] 57, 58, 96, 140, 167 💬
148 cGMP-PKG signaling pathway 💬
 [1] CACNA1S 💬 Pinaverium bromide 💬 Pinaverium [1] 298 💬
149 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [10] 51, 66, 84, 85, 86, 88, 210, 211, 218, 222 💬
150 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Atrasentan hydrochloride 💬 Atrasentan [3] 66, 218, 222 💬
151 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
152 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Sitaxentan sodium 💬 Sitaxentan [1] 86 💬
153 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
154 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [12] 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
155 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [12] 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
156 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
157 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite [1] 58 💬
158 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Avenciguat 💬 Avenciguat [1] 51 💬
159 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Nicorandil 💬 Nicorandil [1] 46 💬
160 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Praliciguat 💬 Praliciguat [1] 222 💬
161 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
162 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Vericiguat 💬 Vericiguat [2] 58, 86 💬
163 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Zagociguat 💬 Zagociguat [1] 21 💬
164 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
165 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
166 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
167 cGMP-PKG signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
168 cGMP-PKG signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [4] 34, 278, 279, 280 💬
169 cGMP-PKG signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
170 cGMP-PKG signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib [1] 34 💬
171 cGMP-PKG signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
172 cGMP-PKG signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
173 cGMP-PKG signaling pathway 💬
 [2] MYH6, MYH7 💬 Aficamten 💬 Aficamten [1] 58 💬
174 cGMP-PKG signaling pathway 💬
 [1] MYH7 💬 Mavacamten 💬 Mavacamten [1] 58 💬
175 cGMP-PKG signaling pathway 💬
 [1] NPR1 💬 Nesiritide 💬 Nesiritide [1] 57 💬
176 cGMP-PKG signaling pathway 💬
 [1] NPR2 💬 Navepegritide 💬 Navepegritide [1] 276 💬
177 cGMP-PKG signaling pathway 💬
 [1] NPR2 💬 Vosoritide 💬 Vosoritide [3] 19, 195, 276 💬
178 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
179 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
180 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
181 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
182 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
183 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
184 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
185 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
186 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
187 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
188 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone [14]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
189 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naltrexone 💬 Naltrexone [14]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
190 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Oxycodone hydrochloride 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
191 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Oxycodone terephthalate 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
192 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Oxycodone 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
193 cGMP-PKG signaling pathway 💬
 [3] PDE2A, PDE3A, PDE3B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
194 cGMP-PKG signaling pathway 💬
 [3] PDE2A, PDE3A, PDE3B 💬 Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
195 cGMP-PKG signaling pathway 💬
 [3] PDE2A, PDE3A, PDE3B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
196 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 Cilostazol 💬 Cilostazol [7]  6 , 13, 46, 48, 51, 70, 124 💬
197 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 Ensifentrine 💬 Ensifentrine [1] 299 💬
198 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬
199 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 Levosimendan 💬 Levosimendan [2]  2 , 57 💬
200 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 Milrinone 💬 Milrinone [1] 294 💬
201 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 Milrinone lactate 💬 Milrinone [1] 294 💬
202 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Dipyridamole 💬 Dipyridamole [7] 46, 49, 51, 66, 96, 222, 224 💬
203 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Sildenafil citrate 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
204 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Sildenafil 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
205 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Tadalafil 💬 Tadalafil [8]  6 , 51, 75, 77, 84, 86, 113, 210 💬
206 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Udenafil 💬 Udenafil [2] 86, 210 💬
207 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Vardenafil 💬 Vardenafil [3] 13, 86, 299 💬
208 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Vardenafil hydrochloride 💬 Vardenafil [3] 13, 86, 299 💬
209 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
210 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus [1] 160 💬
211 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [37]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
212 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [37]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
213 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin [2] 49, 222 💬
214 cGMP-PKG signaling pathway 💬
 [1] PRKCE 💬 Sotrastaurin 💬 Sotrastaurin [1] 97 💬
215 cGMP-PKG signaling pathway 💬
 [1] PRKCE 💬 Sotrastaurin acetate 💬 Sotrastaurin [1] 97 💬
216 cGMP-PKG signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
217 cGMP-PKG signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
218 cGMP-PKG signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
219 cGMP-PKG signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
220 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
221 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬