Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
4 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
5 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
6 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
7 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A [1] SCN5A 💬
|
Quinidine Quinidine 💬
| Quinidine | 002 [3] 2 , 8 , 13 💬
|
8 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
9 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
10 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
11 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
12 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
13 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
14 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
15 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
16 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
17 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
18 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
19 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
20 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
21 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
22 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
23 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
24 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
25 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC6A3 [1] SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
26 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
27 | Aldosterone-regulated sodium reabsorption 💬 13 genes, 14 drugs (DrugBank) and 25 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
28 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
29 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
30 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
31 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
32 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
33 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
34 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
35 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
36 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
37 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
38 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
39 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
40 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
41 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC6A3 [1] SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
42 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
ADRA1A [1] ADRA1A 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
43 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
44 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
45 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
46 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
47 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
48 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
49 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
50 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
51 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
52 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
53 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
54 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
NR1H4 [1] NR1H4 💬
|
Ursodiol Ursodiol 💬
| Ursodeoxycholic acid | 006 [14] 6 , 8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
|
55 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
56 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
57 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
58 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
59 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
60 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
61 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
62 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
63 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
64 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [1] HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
65 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
66 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
67 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
68 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
69 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
70 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
71 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [2] DRD2, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
72 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
73 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
74 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
75 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
76 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
77 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
78 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
79 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
80 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
81 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
82 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
83 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
84 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
85 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Rilmenidine Rilmenidine 💬
| Rilmenidine | 008 [1] 8 💬
|
86 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
87 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
88 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
89 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
90 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
91 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
92 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
93 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE [1] ACHE 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
94 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
95 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
96 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
97 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
98 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
99 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
100 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
|
Melatonin Melatonin 💬
| Melatonin | 006 [12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
|
101 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
|
Ramelteon Ramelteon 💬
| Ramelteon | 006 [3] 6 , 8 , 46 💬
|
102 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 25 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
103 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
104 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
105 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
106 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
107 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
108 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
109 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
110 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
111 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
112 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
113 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
114 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
115 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
116 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
117 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
118 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
119 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CYP17A1 [1] CYP17A1 💬
|
Ketoconazole Ketoconazole 💬
| Ketoconazole | 008 [3] 8 , 13, 75 💬
|
120 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CYP17A1 [1] CYP17A1 💬
|
Ketoconazole Ketoconazole 💬
| Ketoconazole | 008 [3] 8 , 13, 75 💬
|
121 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
122 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
123 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
124 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
125 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
126 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
127 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
128 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
129 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
130 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
131 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
132 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
133 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
134 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A [1] SCN1A 💬
|
Quinidine Quinidine 💬
| Quinidine | 002 [3] 2 , 8 , 13 💬
|
135 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
136 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
137 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
138 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC6A3 [1] SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
139 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
140 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
141 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
142 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
143 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
144 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
145 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
146 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
147 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
148 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
149 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
150 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
151 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
152 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
153 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
154 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
155 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
156 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
157 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [2] DRD2, HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
158 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
159 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
160 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
161 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
162 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
163 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
164 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
165 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
166 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
167 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
168 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
169 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
170 | Glycerophospholipid metabolism 💬 1 gene, 5 drugs (DrugBank) and 11 diseases |
ACHE [1] ACHE 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
171 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
172 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
173 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
174 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
175 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
176 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
177 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
178 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
179 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
180 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
181 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
182 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
183 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
184 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
185 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
186 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
187 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
188 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HRH1 [4] HRH1, HTR2A, HTR2B, HTR2C 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
189 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HTR2A [1] HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
190 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
191 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
192 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
193 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
194 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
195 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
196 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
197 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
198 | Leukocyte transendothelial migration 💬 13 genes, 14 drugs (DrugBank) and 30 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
199 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
200 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
201 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
202 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
203 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
204 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
205 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
206 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
207 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
208 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
209 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
210 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
211 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
212 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
213 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP17A1 [1] CYP17A1 💬
|
Ketoconazole Ketoconazole 💬
| Ketoconazole | 008 [3] 8 , 13, 75 💬
|
214 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
215 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
216 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [3] ABL1, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
217 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
218 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
219 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
220 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
221 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
222 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Rilmenidine Rilmenidine 💬
| Rilmenidine | 008 [1] 8 💬
|
223 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
224 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
225 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
226 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
227 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
228 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
229 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
230 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
231 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
232 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
233 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
234 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
235 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
|
Melatonin Melatonin 💬
| Melatonin | 006 [12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
|
236 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
|
Ramelteon Ramelteon 💬
| Ramelteon | 006 [3] 6 , 8 , 46 💬
|
237 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
238 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
239 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
240 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
241 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
242 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
243 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
244 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
245 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
246 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
247 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
248 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
249 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
250 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
251 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
252 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
CYP17A1 [1] CYP17A1 💬
|
Ketoconazole Ketoconazole 💬
| Ketoconazole | 008 [3] 8 , 13, 75 💬
|
253 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A [2] ATP4A, ATP4B 💬
|
Omeprazole Omeprazole 💬
| Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
|
254 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
255 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
256 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
257 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
258 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
259 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
260 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
261 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
262 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
263 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
264 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
265 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 [1] SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
266 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
267 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
268 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
269 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
NQO1 [1] NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
270 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
271 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
272 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
273 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
274 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
275 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
276 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
277 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
278 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
279 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
280 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
281 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
282 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
283 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
284 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
285 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
286 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
287 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
288 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
289 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
290 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
291 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
CYP17A1 [1] CYP17A1 💬
|
Ketoconazole Ketoconazole 💬
| Ketoconazole | 008 [3] 8 , 13, 75 💬
|
292 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
293 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
294 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
295 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
296 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
297 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
298 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CNR1 [1] CNR1 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
299 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CNR1 [1] CNR1 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
300 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
301 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
302 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
303 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
304 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
305 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
306 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
307 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
308 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
309 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
310 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
311 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
312 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
313 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
314 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
315 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
316 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
317 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
318 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
319 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
320 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CNR1 [1] CNR1 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
321 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CNR1 [1] CNR1 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
322 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
323 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
324 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
325 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
326 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
327 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
328 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
329 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
330 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [1] HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
331 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
332 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
333 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
334 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
335 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Citalopram Citalopram 💬
| Citalopram | 006 [7] 6 , 8 , 13, 18, 46, 98, 127 💬
|
336 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
337 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
338 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
339 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
340 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
341 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
342 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
343 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
344 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP17A1 [1] CYP17A1 💬
|
Ketoconazole Ketoconazole 💬
| Ketoconazole | 008 [3] 8 , 13, 75 💬
|
345 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC18A2 [1] SLC18A2 💬
|
Deutetrabenazine Deutetrabenazine 💬
| Deutetrabenazine | 008 [1] 8 💬
|
346 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC18A2 [1] SLC18A2 💬
|
Tetrabenazine Tetrabenazine 💬
| Tetrabenazine | 008 [1] 8 💬
|
347 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC18A2 [1] SLC18A2 💬
|
Valbenazine Valbenazine 💬
| Valbenazine | 008 [1] 8 💬
|
348 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [1] SLC6A2 💬
|
Atomoxetine Atomoxetine 💬
| Atomoxetine | 006 [4] 6 , 8 , 13, 17 💬
|
349 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Bupropion Bupropion 💬
| Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬
|
350 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Citalopram Citalopram 💬
| Citalopram | 006 [7] 6 , 8 , 13, 18, 46, 98, 127 💬
|
351 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
352 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
353 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
354 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
355 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
356 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
357 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
358 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
|
Quinidine Quinidine 💬
| Quinidine | 002 [3] 2 , 8 , 13 💬
|
359 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
360 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
361 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
362 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
363 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
364 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
365 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
366 | Thyroid hormone synthesis 💬 7 genes, 6 drugs (DrugBank) and 7 diseases |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 [3] 8 , 46, 210 💬
|
367 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
368 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
369 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
370 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
371 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
GRIA3 [1] GRIA3 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
372 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
373 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 [2] NQO1, VKORC1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
374 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
375 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
376 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
377 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|