Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Axon guidance 💬
 [1] SMO 💬 Taladegib 💬 Taladegib [1] 85 💬
2 Axon guidance 💬
 [1] SMO 💬 Vismodegib 💬 Vismodegib [1] 85 💬
3 Basal cell carcinoma 💬
 [1] SMO 💬 Taladegib 💬 Taladegib [1] 85 💬
4 Basal cell carcinoma 💬
 [1] SMO 💬 Vismodegib 💬 Vismodegib [1] 85 💬
5 Hedgehog signaling pathway 💬
 [1] SMO 💬 Taladegib 💬 Taladegib [1] 85 💬
6 Hedgehog signaling pathway 💬
 [1] SMO 💬 Vismodegib 💬 Vismodegib [1] 85 💬
7 Pathways in cancer 💬
 [1] SMO 💬 Taladegib 💬 Taladegib [1] 85 💬
8 Pathways in cancer 💬
 [1] SMO 💬 Vismodegib 💬 Vismodegib [1] 85 💬
9 Proteoglycans in cancer 💬
 [1] SMO 💬 Taladegib 💬 Taladegib [1] 85 💬
10 Proteoglycans in cancer 💬
 [1] SMO 💬 Vismodegib 💬 Vismodegib [1] 85 💬
11 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
12 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
13 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Caffeine citrate 💬 Caffeine [8]  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
14 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Istradefylline 💬 Istradefylline [1]  6  💬
15 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Preladenant 💬 Preladenant [1]  6  💬
16 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Regadenoson 💬 Regadenoson [1] 58 💬
17 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Regadenoson 💬 Regadenoson [1] 58 💬
18 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 Tozadenant 💬 Tozadenant [1]  6  💬
19 Vascular smooth muscle contraction 💬
 [2] ADORA2A, ADORA2B 💬 Adenosine 💬 Adenosine [3] 13, 58, 65 💬
20 Vascular smooth muscle contraction 💬
 [2] ADORA2A, ADORA2B 💬 Adenosine phosphate 💬 Adenosine phosphate [1] 46 💬
21 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
22 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
23 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
24 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
25 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
26 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Alfuzosin hydrochloride 💬 Alfuzosin [1] 13 💬
27 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
28 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [1]  6  💬
29 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Amiodarone hydrochloride 💬 Amiodarone [1] 127 💬
30 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Amiodarone 💬 Amiodarone [1] 127 💬
31 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Carvedilol 💬 Carvedilol [6]  6 , 46, 57, 86, 113, 210 💬
32 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Carvedilol phosphate 💬 Carvedilol [6]  6 , 46, 57, 86, 113, 210 💬
33 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Dipivefrin hydrochloride 💬 Dipivefrin [1]  6  💬
34 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
35 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin mesylate 💬 Doxazosin [1] 67 💬
36 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [1] 67 💬
37 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
38 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
39 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ephedrine hydrochloride 💬 Ephedrine [1] 11 💬
40 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ephedrine sulfate 💬 Ephedrine [1] 11 💬
41 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Epinephrine 💬 Epinephrine [1] 46 💬
42 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Epinephrine hydrochloride 💬 Epinephrine [1] 46 💬
43 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Epinephrine bitartrate 💬 Epinephrine [1] 46 💬
44 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ergoloid mesylates 💬 Ergoloid mesylate [2]  6 , 206 💬
45 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ifenprodil tartrate 💬 Ifenprodil [1] 13 💬
46 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Ifenprodil 💬 Ifenprodil [1] 13 💬
47 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine hydrochloride 💬 Midodrine [3]  6 , 17, 58 💬
48 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
49 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
50 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Norepinephrine bitartrate 💬 Norepinephrine [2] 22, 296 💬
51 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Norepinephrine hydrochoride 💬 Norepinephrine [2] 22, 296 💬
52 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
53 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
54 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine hydrochloride 💬 Phenylephrine [1] 22 💬
55 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
56 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine bitartrate 💬 Phenylephrine [1] 22 💬
57 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Pseudoephedrine hydrochloride 💬 Pseudoephedrine [1] 17 💬
58 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Pseudoephedrine sulfate 💬 Pseudoephedrine [1] 17 💬
59 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
60 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin hydrochloride 💬 Tamsulosin [1] 13 💬
61 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
62 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin hydrochloride 💬 Terazosin [1]  6  💬
63 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
64 Vascular smooth muscle contraction 💬
 [7] ADRA1A, ADRA1B, ADRA1D, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol [1]  8  💬
65 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Angiotensin II 💬 Angiotensin II [7] 17, 46, 49, 66, 218, 222, 224 💬
66 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Angiotensin II 💬 Angiotensin II [7] 17, 46, 49, 66, 218, 222, 224 💬
67 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II [7] 17, 46, 49, 66, 218, 222, 224 💬
68 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Azilsartan medoxomil 💬 Azilsartan medoxomil [1] 66 💬
69 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Azilsartan 💬 Azilsartan medoxomil [1] 66 💬
70 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Azilsartan kamedoxomil 💬 Azilsartan medoxomil [1] 66 💬
71 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Buloxibutid 💬 Buloxibutid [1] 85 💬
72 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid [1] 85 💬
73 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
74 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Irbesartan 💬 Irbesartan [4] 66, 167, 168, 222 💬
75 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Losartan potassium 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
76 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
77 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
78 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Valsartan 💬 Valsartan [8] 57, 58, 66, 75, 86, 210, 222, 224 💬
79 Vascular smooth muscle contraction 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
80 Vascular smooth muscle contraction 💬
 [2] AVPR1A, AVPR1B 💬 Terlipressin 💬 Terlipressin [1] 299 💬
81 Vascular smooth muscle contraction 💬
 [2] AVPR1A, AVPR1B 💬 Terlipressin acetate 💬 Terlipressin [1] 299 💬
82 Vascular smooth muscle contraction 💬
 [2] AVPR1A, AVPR1B 💬 Vasopressin 💬 Vasopressin [2] 210, 225 💬
83 Vascular smooth muscle contraction 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
84 Vascular smooth muscle contraction 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
85 Vascular smooth muscle contraction 💬
 [2] BRAF, RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
86 Vascular smooth muscle contraction 💬
 [2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
87 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine [3] 51, 67, 298 💬
88 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine [3] 51, 67, 298 💬
89 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [3] 51, 67, 298 💬
90 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine [3] 51, 67, 298 💬
91 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
92 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem [4] 51, 58, 86, 88 💬
93 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem [4] 51, 58, 86, 88 💬
94 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem [4] 51, 58, 86, 88 💬
95 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine [1]  6  💬
96 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine [2] 70, 86 💬
97 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬
98 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine [1] 81 💬
99 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬
100 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline [2] 58, 272 💬
101 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
102 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine [1] 226 💬
103 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine [1] 226 💬
104 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate [5]  6 , 140, 144, 156, 193 💬
105 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil [4] 58, 96, 140, 167 💬
106 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
107 Vascular smooth muscle contraction 💬
 [1] CACNA1S 💬 Pinaverium bromide 💬 Pinaverium [1] 298 💬
108 Vascular smooth muscle contraction 💬
 [1] CALC 💬 Eptinezumab 💬 Eptinezumab [1] 226 💬
109 Vascular smooth muscle contraction 💬
 [1] CALC 💬 Fremanezumab 💬 Fremanezumab [2] 124, 226 💬
110 Vascular smooth muscle contraction 💬
 [1] CALC 💬 Galcanezumab 💬 Galcanezumab [1] 226 💬
111 Vascular smooth muscle contraction 💬
 [1] CALCRL 💬 Atogepant 💬 Atogepant [1] 226 💬
112 Vascular smooth muscle contraction 💬
 [1] CALCRL 💬 Erenumab 💬 Erenumab [1] 226 💬
113 Vascular smooth muscle contraction 💬
 [1] CALCRL 💬 Rimegepant 💬 Rimegepant [1] 226 💬
114 Vascular smooth muscle contraction 💬
 [1] CALCRL 💬 Rimegepant sulfate 💬 Rimegepant [1] 226 💬
115 Vascular smooth muscle contraction 💬
 [1] CALCRL 💬 Ubrogepant 💬 Ubrogepant [1] 226 💬
116 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [8] 51, 66, 84, 85, 86, 88, 210, 211 💬
117 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Atrasentan hydrochloride 💬 Atrasentan [3] 66, 218, 222 💬
118 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [11] 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
119 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [11] 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
120 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
121 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
122 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Sitaxentan sodium 💬 Sitaxentan [1] 86 💬
123 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
124 Vascular smooth muscle contraction 💬
 [3] GUCY1A, GUCY1A, GUCY1B 💬 Zagociguat 💬 Zagociguat [1] 21 💬
125 Vascular smooth muscle contraction 💬
 [3] GUCY1A, GUCY1A, GUCY1B 💬 Amyl nitrite 💬 Amyl Nitrite [1] 58 💬
126 Vascular smooth muscle contraction 💬
 [3] GUCY1A, GUCY1A, GUCY1B 💬 Avenciguat 💬 Avenciguat [1] 51 💬
127 Vascular smooth muscle contraction 💬
 [3] GUCY1A, GUCY1A, GUCY1B 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
128 Vascular smooth muscle contraction 💬
 [3] GUCY1A, GUCY1A, GUCY1B 💬 Vericiguat 💬 Vericiguat [1] 86 💬
129 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
130 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
131 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib [1] 280 💬
132 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [4] 34, 278, 279, 280 💬
133 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
134 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib [1] 34 💬
135 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
136 Vascular smooth muscle contraction 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
137 Vascular smooth muscle contraction 💬
 [1] NPR1 💬 Nesiritide 💬 Nesiritide [1] 58 💬
138 Vascular smooth muscle contraction 💬
 [2] NPR1, NPR2 💬 Erythrityl tetranitrate 💬 Erythrityl tetranitrate [1] 46 💬
139 Vascular smooth muscle contraction 💬
 [1] NPR2 💬 Vosoritide 💬 Vosoritide [3] 19, 195, 276 💬
140 Vascular smooth muscle contraction 💬
 [1] PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin [1] 168 💬
141 Vascular smooth muscle contraction 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
142 Vascular smooth muscle contraction 💬
 [4] PRKCD, PRKCE, PRKCH, PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin [1] 97 💬
143 Vascular smooth muscle contraction 💬
 [4] PRKCD, PRKCE, PRKCH, PRKCQ 💬 Sotrastaurin acetate 💬 Sotrastaurin [1] 97 💬
144 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Beraprost sodium 💬 Beraprost [1] 86 💬
145 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Beraprost 💬 Beraprost [1] 86 💬
146 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Epoprostenol 💬 Epoprostenol [1] 86 💬
147 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Epoprostenol sodium 💬 Epoprostenol [1] 86 💬
148 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Esuberaprost 💬 Esuberaprost [1] 86 💬
149 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Esuberaprost sodium 💬 Esuberaprost [1] 86 💬
150 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬
151 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Iloprost 💬 Iloprost [4] 51, 84, 85, 86 💬
152 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Iloprost tromethamine 💬 Iloprost [4] 51, 84, 85, 86 💬
153 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Ralinepag 💬 Ralinepag [1] 86 💬
154 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Selexipag 💬 Selexipag [6] 47, 51, 70, 84, 86, 88 💬
155 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Treprostinil 💬 Treprostinil [5] 51, 85, 86, 88, 210 💬
156 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Treprostinil monosodium salt 💬 Treprostinil [5] 51, 85, 86, 88, 210 💬
157 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Treprostinil diolamine 💬 Treprostinil [5] 51, 85, 86, 88, 210 💬
158 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 Treprostinil palmitil 💬 Treprostinil palmitil [1] 86 💬
159 Vascular smooth muscle contraction 💬
 [2] ROCK1, ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
160 Vascular smooth muscle contraction 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
161 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
162 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬

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