Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine [3] 51, 67, 298 💬
2 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine [3] 51, 67, 298 💬
3 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [3] 51, 67, 298 💬
4 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine [3] 51, 67, 298 💬
5 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol [1]  8  💬
6 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
7 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem [4] 51, 58, 86, 88 💬
8 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem [4] 51, 58, 86, 88 💬
9 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem [4] 51, 58, 86, 88 💬
10 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine [1]  6  💬
11 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine [2] 70, 86 💬
12 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬
13 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine [1] 81 💬
14 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬
15 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline [2] 58, 272 💬
16 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
17 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine [1] 226 💬
18 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine [1] 226 💬
19 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate [5]  6 , 140, 144, 156, 193 💬
20 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil [4] 58, 96, 140, 167 💬
21 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
22 GnRH signaling pathway 💬
 [1] CACNA1S 💬 Pinaverium bromide 💬 Pinaverium [1] 298 💬
23 GnRH signaling pathway 💬
 [1] EGFR 💬 Afatinib 💬 Afatinib [1] 285 💬
24 GnRH signaling pathway 💬
 [1] EGFR 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
25 GnRH signaling pathway 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
26 GnRH signaling pathway 💬
 [1] EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib [2] 94, 160 💬
27 GnRH signaling pathway 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [2] 94, 160 💬
28 GnRH signaling pathway 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
29 GnRH signaling pathway 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
30 GnRH signaling pathway 💬
 [1] EGFR 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
31 GnRH signaling pathway 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
32 GnRH signaling pathway 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
33 GnRH signaling pathway 💬
 [1] EGFR 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
34 GnRH signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
35 GnRH signaling pathway 💬
 [1] GNRHR 💬 Cetrorelix acetate 💬 Cetrorelix [1] 46 💬
36 GnRH signaling pathway 💬
 [1] GNRHR 💬 Cetrorelix 💬 Cetrorelix [1] 46 💬
37 GnRH signaling pathway 💬
 [1] GNRHR 💬 Gonadorelin hydrochloride 💬 Gonadorelin [1] 76 💬
38 GnRH signaling pathway 💬
 [1] GNRHR 💬 Gonadorelin acetate 💬 Gonadorelin [1] 76 💬
39 GnRH signaling pathway 💬
 [1] GNRHR 💬 Gonadorelin 💬 Gonadorelin [1] 76 💬
40 GnRH signaling pathway 💬
 [1] GNRHR 💬 Goserelin acetate 💬 Goserelin [1]  1  💬
41 GnRH signaling pathway 💬
 [1] GNRHR 💬 Goserelin 💬 Goserelin [1]  1  💬
42 GnRH signaling pathway 💬
 [1] GNRHR 💬 Histrelin acetate 💬 Histrelin [1] 76 💬
43 GnRH signaling pathway 💬
 [1] GNRHR 💬 Histrelin 💬 Histrelin [1] 76 💬
44 GnRH signaling pathway 💬
 [1] GNRHR 💬 Leuprolide acetate 💬 Leuprolide [5]  1 ,  2 ,  3 , 67, 76 💬
45 GnRH signaling pathway 💬
 [1] GNRHR 💬 Leuprorelin 💬 Leuprolide [5]  1 ,  2 ,  3 , 67, 76 💬
46 GnRH signaling pathway 💬
 [1] GNRHR 💬 Leuprolide mesylate 💬 Leuprolide [5]  1 ,  2 ,  3 , 67, 76 💬
47 GnRH signaling pathway 💬
 [1] GNRHR 💬 Triptorelin 💬 Triptorelin [2] 49, 76 💬
48 GnRH signaling pathway 💬
 [1] GNRHR 💬 Triptorelin pamoate 💬 Triptorelin [2] 49, 76 💬
49 GnRH signaling pathway 💬
 [1] GNRHR 💬 Triptorelin acetate 💬 Triptorelin [2] 49, 76 💬
50 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
51 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
52 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib [1] 280 💬
53 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [4] 34, 278, 279, 280 💬
54 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
55 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib [1] 34 💬
56 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
57 GnRH signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
58 GnRH signaling pathway 💬
 [4] P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
59 GnRH signaling pathway 💬
 [4] P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
60 GnRH signaling pathway 💬
 [1] PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin [1] 168 💬
61 GnRH signaling pathway 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
62 GnRH signaling pathway 💬
 [1] PRKCD 💬 Sotrastaurin 💬 Sotrastaurin [1] 97 💬
63 GnRH signaling pathway 💬
 [1] PRKCD 💬 Sotrastaurin acetate 💬 Sotrastaurin [1] 97 💬
64 GnRH signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
65 GnRH signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
66 GnRH signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
67 GnRH signaling pathway 💬
 [1] SRC 💬 Bosutinib hydrate 💬 Bosutinib [2]  2 , 67 💬
68 GnRH signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
69 GnRH signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
70 GnRH signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬