113. Muscular dystrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 826 / Drugs : 680 - (DrugBank : 126) / Drug target genes : 86 - Drug target pathways : 188
Muscular dystrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 113 | Muscular dystrophy | - |
| 46 | Malignant rheumatoid arthritis | 34.049 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 31.809 |
| 96 | Crohn disease | 30.186 |
| 6 | Parkinson disease | 29.859 |
| 2 | Amyotrophic lateral sclerosis | 24.903 |
| 97 | Ulcerative colitis | 16.169 |
| 8 | Huntington disease | 15.959 |
| 85 | Idiopathic interstitial pneumonia | 15.277 |
| 107 | Juvenile idiopathic arthritis | 15.173 |
| 49 | Systemic lupus erythematosus | 14.774 |
| 86 | Pulmonary arterial hypertension | 14.195 |
| 70 | Spinal stenosis | 13.857 |
| 226 | Interstitial cystitis with Hunners ulcer | 12.946 |
| 58 | Hypertrophic cardiomyopathy | 12.288 |
| 65 | Primary immunodeficiency | 11.576 |
| 299 | Cystic fibrosis | 10.433 |
| 17 | Multiple system atrophy | 10.131 |
| 222 | Primary nephrotic syndrome | 10.131 |
| 38 | Stevens-Johnson syndrome | 10.088 |
| 127 | Frontotemporal lobar degeneration | 10.042 |
| 51 | Scleroderma | 9.988 |
| 11 | Myasthenia gravis | 9.470 |
| 28 | Systemic amyloidosis | 8.903 |
| 215 | Tetralogy of Fallot | 8.814 |
| 206 | Fragile X syndrome | 8.708 |
| 78 | Hypopituitarism | 8.579 |
| 5 | Progressive supranuclear palsy | 8.063 |
| 21 | Mitochondrial disease | 7.384 |
| 34 | Neurofibromatosis | 7.263 |
| 168 | Ehlers-Danlos syndrome | 7.232 |
| 57 | Idiopathic dilated cardiomyopathy | 7.232 |
| 169 | Menkes disease | 7.232 |
| 170 | Occipital horn syndrome | 7.232 |
| 53 | Sjogren syndrome | 6.864 |
| 36 | Epidermolysis bullosa | 6.373 |
| 118 | Myelomeningocele | 6.229 |
| 224 | Purpura nephritis | 5.949 |
| 66 | IgA nephropathy | 5.718 |
| 158 | Tuberous sclerosis | 5.718 |
| 285 | Fanconi anemia | 5.332 |
| 60 | Aplastic anemia | 5.172 |
| 1 | Spinal and bulbar muscular atrophy | 5.149 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 22 | Moyamoya disease | 4.661 |
| 3 | Spinal muscular atrophy | 4.605 |
| 64 | Thrombotic thrombocytopenic purpura | 4.542 |
| 227 | Osler disease | 4.357 |
| 210 | Single Ventricle | 4.290 |
| 151 | Rasmussen encephalitis | 4.237 |
| 83 | Addison disease | 4.237 |
| 41 | Giant cell arteritis | 4.212 |
| 164 | Oculocutaneous albinism | 4.138 |
| 19 | Lysosomal storage disease | 4.103 |
| 50 | Dermatomyositis | 4.102 |
| 4 | Primary lateral sclerosis | 3.996 |
| 274 | Osteogenesis Imperfecta | 3.915 |
| 298 | Hereditary pancreatitis | 3.908 |
| 84 | Sarcoidosis | 3.840 |
| 269 | Pyogenic arthritis | 3.710 |
| 256 | Muscle glycogenosis | 3.587 |
| 39 | Toxic epidermal necrolysis | 3.550 |
| 18 | Spinocerebellar degeneration | 3.540 |
| 63 | Idiopathic thrombocytopenic purpura | 3.540 |
| 228 | Bronchiolitis obliterans | 3.453 |
| 90 | Retinitis pigmentosa | 3.390 |
| 156 | Rett syndrome | 3.329 |
| 193 | Prader-Willi syndrome | 3.323 |
| 81 | Congenital adrenal hyperplasia | 3.305 |
| 286 | Hereditary sideroblastic anemia | 3.284 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 3.230 |
| 288 | Autoimmune acquired coagulation factor deficiency | 3.230 |
| 283 | Acquired pure red cell aplasia | 3.230 |
| 67 | Polycystic kidney disease | 3.179 |
| 95 | Autoimmune hepatitis | 3.103 |
| 171 | Wilson disease | 3.000 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 225 | Congenital nephrogenic diabetes insipidus | 2.929 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 2.920 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 2.887 |
| 284 | Diamond-Blackfan anemia | 2.794 |
| 218 | Alport syndrome | 2.757 |
| 76 | Pituitary gonadotropin secretion hyperthyroidism | 2.757 |
| 93 | Primary biliary cholangitis | 2.665 |
| 231 | Alpha-1-antitrypsin deficiency | 2.665 |
| 326 | Osteopetrosis | 2.631 |
| 56 | Behcet disease | 2.621 |
| 40 | Takayasu arteritis | 2.558 |
| 205 | Fragile X syndrome related disease | 2.558 |
| 10 | Charcot-Marie-Tooth disease | 2.504 |
| 42 | Polyarteritis nodosa | 2.492 |
| 75 | Cushing disease | 2.480 |
| 271 | Ankylosing spondylitis | 2.434 |
| 160 | Congenital ichthyosis | 2.407 |
| 55 | Relapsing polychondritis | 2.331 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 2.331 |
| 251 | Urea cycle disorder | 2.288 |
| 333 | Hutchinson-Gilford syndrome | 2.288 |
| 71 | Idiopathic osteonecrosis of the femoral head | 2.288 |
| 162 | Pemphigoid | 2.139 |
| 212 | Tricuspid atresia | 2.136 |
| 20 | Adrenoleukodystrophy | 2.080 |
| 203 | 22q11.2 deletion syndrome | 2.058 |
| 77 | Growth hormone secreting pituitary adenoma | 2.000 |
| 337 | Homocystinuria | 2.000 |
| 257 | Hepatic glycogenosis | 2.000 |
| 282 | Congenital dyserythropoietic anemia | 2.000 |
| 26 | HTLV-1-associated myelopathy | 1.967 |
| 61 | Autoimmune hemolytic anemia | 1.904 |
| 294 | Congenital diaphragmatic hernia | 1.861 |
| 211 | Hypoplastic left heart syndrome | 1.861 |
| 278 | Huge lymphatic malformation with cervicofacial lesion | 1.861 |
| 167 | Marfan syndrome | 1.763 |
| 114 | Non-dystrophic myotonia syndrome | 1.695 |
| 265 | Lipodystrophy | 1.304 |
| 74 | Prolactin secreting pituitary adenoma | 1.203 |
| 301 | Macular dystrophy | 1.102 |
| 179 | Williams syndrome | 1.102 |
| 238 | Vitamin D-resistant rickets | 1.034 |
| 235 | Hypoparathyroidism | 1.034 |
| 111 | Congenital myopathy | 1.000 |
| 108 | TNF receptor-associated periodic syndrome | 1.000 |
| 267 | Hyper-IgD syndrome | 1.000 |
| 191 | Werner syndrome | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |