Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetylsalicylic acid [2] Acetylsalicylic acid; Aspirin[1] Aspirin 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
2 Albuterol [2] Albuterol; Salbutamol[2] Albuterol sulfate ,
Albuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[16] 2, 3, 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
3 Allogeneic Cardiosphere-Derived Cells [1] Allogeneic cardiosphere-derived cells---[1] 113 💬
4 AOC 1001 [1] AOC 1001---[1] 113 💬
5 Ataluren [1] Ataluren[1] Ataluren 💬 --[6] 19, 113, 140, 246, 299, 329 💬
6 ATL1102 [1] ATL1102---[2] 13, 113 💬
7 ATX-01 [1] ATX-01---[1] 113 💬
8 ATYR-1940 [1] ATYR1940---[1] 113 💬
9 BB-301 [0] ---[1] 113 💬
10 Bisoprolol [2] Bisoprolol; Bisoprolol fumarate[2] Bisoprolol fumarate ,
Bisoprolol 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 58, 67, 86, 113 💬
11 BLS-M22 [1] BLS-M22---[1] 113 💬
12 BMN-044 [2] BMN 044; PRO044---[1] 113 💬
13 BMN-045 [2] BMN 045; PRO045---[1] 113 💬
14 BMN-053 [2] BMN053; PRO053---[1] 113 💬
15 Bocidelpar [1] Bocidelpar[2] Bocidelpar ,
Bocidelpar sulfate 💬 		[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 113 💬
16 Botulinum toxin type A [5] Botulinum toxin A; Botulinum toxin type A; BTX-A; Incobotulinumtoxina; Onabotulinumtoxina[2] Botulinum toxin type A ,
Prabotulinumtoxin A 💬 		[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 47, 51, 70, 113, 149, 171, 226 💬
17 Calcifediol [1] Calcifediol[1] Calcifediol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 86, 113 💬
18 Canakinumab [1] Canakinumab[1] Canakinumab 💬 [1] IL1B 💬 [43] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
19 Carvedilol [1] Carvedilol[2] Carvedilol ,
Carvedilol phosphate 💬 		[5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		[15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 46, 57, 86, 113, 210 💬
20 Casimersen [1] Casimersen[1] Casimersen 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
21 Citrulline [1] Citrulline[2] L-Citrulline ,
Citrulline malate 💬 		--[1] 113 💬
22 Clenbuterol [2] Clenbuterol; Clenbuterol hydrochloride[2] Clenbuterol hydrochloride ,
Clenbuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 1, 2, 6, 113, 256 💬
23 Creatine [3] Acetic acid; Creatine; Creatine monohydrate---[14] 1, 2, 6, 8, 13, 21, 46, 49, 50, 97, 113, 156, 201, 337 💬
24 Cyclosporine [6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[1] Cyclosporine 💬 [5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[42] 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
25 Deflazacort [1] Deflazacort[1] Deflazacort 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 30, 113 💬
26 Delandistrogene moxeparvovec [1] Delandistrogene moxeparvovec[1] Delandistrogene moxeparvovec 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
27 Dexmedetomidine [3] Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
28 Domagrozumab [1] PF-06252616[1] Domagrozumab 💬 [1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 113 💬
29 Drisapersen [1] Drisapersen[1] Drisapersen 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
30 DT-DEC01 [1] DT-DEC01---[1] 113 💬
31 DYNE-251 [1] DYNE-251---[1] 113 💬
32 Edasalonexent [1] Edasalonexent[1] Edasalonexent 💬 [1] RELA 💬 [75] AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬[1] 113 💬
33 Empagliflozin [1] Empagliflozin[1] Empagliflozin 💬 --[13] 46, 58, 65, 67, 72, 77, 86, 96, 97, 113, 257, 298, 299 💬
34 Enalapril [2] Enalapril; Enalapril maleate[2] Enalapril maleate ,
Enalapril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[8] 13, 19, 46, 66, 113, 210, 222, 279 💬
35 Epicatechin [1] Epicatechin---[2] 86, 113 💬
36 Epigallocatechin [1] Epigallocatechin---[5] 8, 13, 28, 85, 113 💬
37 Eplerenone [1] Eplerenone[1] Eplerenone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[4] 75, 113, 210, 215 💬
38 Esomeprazole [3] Esomeprazole; Esomeprazole magnesium; Omeprazole[5] Esomeprazole magnesium ,
Esomeprazole sodium ,
Esomeprazole ,
Esomeprazole strontium ,
Esomeprazole magnesium dihydrate 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
39 Eteplirsen [1] Eteplirsen[1] Eteplirsen 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
40 Ezutromid [1] Ezutromid---[1] 113 💬
41 Filgrastim [3] Filgrastim; G-CSF; Granulocyte colony stimulating factor[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[29] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
42 Fordadistrogene movaparvovec [1] Fordadistrogene movaparvovec---[1] 113 💬
43 Gentamicin [2] Gentamicin; Gentamicin sulfate[2] Gentamicin sulfate ,
Gentamicin 💬 		--[3] 36, 113, 299 💬
44 Givinostat [1] Givinostat[1] Givinostat 💬 [11] HDAC10,
HDAC11,
HDAC1_2,
HDAC1_2,
HDAC3,
HDAC4_5,
HDAC4_5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬 		[20] ATP-dependent chromatin remodeling, Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Polycomb repressive complex, TGF-beta signaling pathway, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬[2] 107, 113 💬
45 Golodirsen [1] Golodirsen[1] Golodirsen 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
46 GYM329 [1] GYM329---[2] 3, 113 💬
47 Human Umbilical Cord Mesenchymal Stem Cells [3] Human umbilical cord mesenchymal stem cells; Mesenchymal stromal cells; UC-mscs---[12] 13, 36, 46, 51, 60, 96, 97, 107, 113, 271, 274, 284 💬
48 Ibuprofen [1] Ibuprofen[5] Ibuprofen ,
Ibuprofen aluminum ,
Ibuprofen lysine ,
Ibuprofen sodium ,
Ibuprofen sodium 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[6] 13, 46, 65, 113, 271, 299 💬
49 Icosapent [1] Eicosapentaenoic acid[1] Icosapent 💬 --[9] 46, 48, 49, 96, 97, 113, 296, 297, 338 💬
50 Idebenone [1] Idebenone[1] Idebenone 💬 --[7] 6, 8, 13, 18, 21, 113, 302 💬
51 Ifetroban [2] Ifetroban; Ifetroban sodium[2] Ifetroban ,
Ifetroban sodium 💬 		[1] TBXA2R 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[2] 85, 113 💬
52 Imlifidase [3] HMED-ides; Ides; Imlifidase[1] Imlifidase 💬 --[5] 43, 44, 64, 113, 221 💬
53 Isosorbide [0] [1] Isosorbide 💬 --[1] 113 💬
54 Isosorbide dinitrate [0] [1] Isosorbide dinitrate 💬 --[1] 113 💬
55 Ketamine [3] Ketamine; Ketamine hydrochloride; Nmda[2] Ketamine hydrochloride ,
Ketamine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[6] 6, 13, 70, 113, 156, 215 💬
56 L-arginine [1] L-arginine---[5] 2, 21, 46, 113, 299 💬
57 L-Glutamine [2] Glutamine; L-glutamine[1] Glutamine 💬 --[11] 21, 87, 89, 96, 97, 113, 214, 215, 222, 245, 299 💬
58 Lamotrigine [1] Lamotrigine[1] Lamotrigine 💬 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[6] 13, 34, 38, 113, 114, 144 💬
59 Lisinopril [1] Lisinopril[2] Lisinopril ,
Lisinopril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222 💬
60 Lonafarnib [1] Lonafarnib[1] Lonafarnib 💬 [2] FNTA,
FNTB 💬 		[1] Terpenoid backbone biosynthesis 💬[2] 113, 333 💬
61 Losartan [2] Losartan; Losartan potassium[2] Losartan potassium ,
Losartan 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
62 Losmapimod [1] Losmapimod[1] Losmapimod 💬 [4] P38,
P38,
P38,
P38 💬 		[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[2] 113, 222 💬
63 Magnesium [2] Magnesio; Magnesium---[14] 6, 11, 13, 46, 70, 97, 113, 166, 235, 284, 296, 297, 298, 340 💬
64 Magnesium oxide [1] Magnesium oxide[1] Magnesium oxide 💬 --[3] 6, 113, 166 💬
65 Mannitol [2] Mannite; Mannitol[1] Mannitol 💬 --[6] 6, 13, 60, 96, 113, 299 💬
66 Metformin [3] Metformin; Metformin hydrochloride; Metformina[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[28] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
67 Methylphenidate [2] Methylphenidate; Methylphenidate hydrochloride[2] Methylphenidate hydrochloride ,
Methylphenidate 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
68 Metoprolol [2] Metoprolol; Metoprolol succinate[4] Metoprolol tartrate ,
Metoprolol succinate ,
Metoprolol ,
Metoprolol fumarate 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
69 Mexiletine [2] Mexiletine; Mexiletine hydrochloride[2] Mexiletine hydrochloride ,
Mexiletine 💬 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 1, 2, 10, 113, 114 💬
70 Moxifloxacin [2] Moxifloxacin; Moxifloxacin hydrochloride[3] Moxifloxacin hydrochloride ,
Moxifloxacin ,
Moxifloxacin hydrochloride monohydrate 💬 		--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
71 Nebivolol [1] Nebivolol[2] Nebivolol ,
Nebivolol hydrochloride 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167 💬
72 Omigapil [1] Omigapil---[1] 113 💬
73 Oxatomide [1] Oxatomide[1] Oxatomide 💬 [1] ALOX5 💬 [6] Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113 💬
74 Pamrevlumab [1] Pamrevlumab[1] Pamrevlumab 💬 [1] CTGF 💬 [2] Apelin signaling pathway, Hippo signaling pathway 💬[2] 85, 113 💬
75 Pemirolast [1] Pemirolast[2] Pemirolast potassium ,
Pemirolast 💬 		--[1] 113 💬
76 Pentoxifylline [1] Pentoxifylline[1] Pentoxifylline 💬 --[12] 6, 26, 56, 84, 93, 96, 97, 113, 220, 222, 296, 298 💬
77 Perindopril [2] Perindopril; Perindopril arginine[3] Perindopril erbumine ,
Perindopril ,
Perindopril arginine 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 58, 113, 167, 222 💬
78 Pitolisant [1] Pitolisant[2] Pitolisant ,
Pitolisant hydrochloride 💬 		[1] HRH3 💬 [2] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193 💬
79 Prasterone [3] Dehydroepiandrosterone; Dhea; Prasterone[1] Prasterone 💬 [3] AR,
ESR1,
ESR2 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[6] 49, 53, 83, 86, 96, 113 💬
80 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[41] 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
81 Prednisone [2] Prednisona; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
82 Primidone [1] Primidone[1] Primidone 💬 --[2] 2, 113 💬
83 Ramipril [1] Ramipril[1] Ramipril 💬 [1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257 💬
84 Ranolazine [1] Ranolazine[2] Ranolazine ,
Ranolazine hydrochloride 💬 		--[7] 2, 58, 86, 96, 97, 113, 114 💬
85 Renadirsen [1] Renadirsen---[1] 113 💬
86 Resveratrol [1] Resveratrol---[6] 8, 18, 89, 97, 113, 299 💬
87 RGX-202 [1] RGX-202---[1] 113 💬
88 Ribitol [1] Ribitol[1] Ribitol 💬 --[1] 113 💬
89 Rimeporide [1] Rimeporide---[1] 113 💬
90 Risedronic acid [3] Risedronate; Risedronate sodium; Risedronic acid[3] Risedronate sodium ,
Risedronic acid ,
Risedronate sodium monohydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
91 Satralizumab [2] Sapelizumab; Satralizumab[1] Satralizumab 💬 [1] IL6R 💬 [11] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 11, 13, 86, 113 💬
92 Sevasemten [1] Sevasemten[1] Sevasemten 💬 [8] MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s,
MYH1s 💬 		[2] Cytoskeleton in muscle cells, Motor proteins 💬[1] 113 💬
93 Sildenafil [3] Sildenafil; Sildenafil citrate; Sildenafilo[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[14] 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
94 Sodium nitrate [1] Sodium nitrate---[2] 58, 113 💬
95 Somatotropin [7] Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina[1] Somatropin 💬 [1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[28] 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
96 Spironolactone [1] Spironolactone[1] Spironolactone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[8] 46, 58, 67, 86, 113, 210, 218, 225 💬
97 SRP-6004 [1] SRP-6004---[1] 113 💬
98 SRP-9005 [1] SRP-9005---[1] 113 💬
99 Stamulumab [1] MYO-029[1] Stamulumab 💬 [1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 113 💬
100 Suvodirsen [1] Suvodirsen---[1] 113 💬
101 Tacrolimus [1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[33] 2, 6, 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
102 Tadalafil [2] Tadalafil; Tadalafilo[1] Tadalafil 💬 [1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[8] 6, 51, 75, 77, 84, 86, 113, 210 💬
103 Tamoxifen [2] Tamoxifen; Tamoxifen citrate[2] Tamoxifen citrate ,
Tamoxifen 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 2, 86, 113, 227 💬
104 Testosterone [1] Testosterone[1] Testosterone 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
105 Testosterone decanoate [1] Testosterone decanoate[1] Testosterone decanoate 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113 💬
106 Testosterone enanthate [1] Testosterone enanthate[1] Testosterone enanthate 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113 💬
107 Testosterone isocaproate [1] Testosterone isocaproate---[1] 113 💬
108 Testosterone phenylpropionate [1] Testosterone phenylpropionate[1] Testosterone phenylpropionate 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113 💬
109 Testosterone propionate [1] Testosterone propionate[1] Testosterone propionate 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113 💬
110 Tetracosactide [3] Cosyntropin; Tetracosactide acetate; Tetracosactrin[2] Cosyntropin ,
Tetracosactide acetate 💬 		[1] MC2R 💬 [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 78, 83, 113, 145, 222 💬
111 Tideglusib [1] Tideglusib---[3] 2, 5, 113 💬
112 Tranilast [1] Tranilast[1] Tranilast 💬 --[4] 46, 84, 106, 113 💬
113 Trehalose [2] Cabaletta; Trehalose---[4] 2, 6, 18, 113 💬
114 Ubidecarenone [2] Coenzyme Q10; COQ10[1] Ubidecarenone 💬 --[14] 2, 5, 6, 8, 10, 46, 57, 86, 96, 107, 113, 193, 214, 215 💬
115 Vamorolone [1] Vamorolone[1] Vamorolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 97, 113 💬
116 Vesleteplirsen [1] Vesleteplirsen---[1] 113 💬
117 Viltolarsen [1] Viltolarsen[1] Viltolarsen 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
118 WVE-N531 [1] WVE-N531---[1] 113 💬
119 Zildistrogene varoparvovec [1] RAAV9-CK8-H-µD5---[1] 113 💬