18. Spinocerebellar degeneration Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 83 / Drugs : 83 - (DrugBank : 31) / Drug target genes : 30 - Drug target pathways : 53
Spinocerebellar degeneration and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 18 | Spinocerebellar degeneration | - |
| 13 | Multiple sclerosis | 39.642 |
| 6 | Parkinson disease | 36.501 |
| 206 | Fragile X syndrome | 33.600 |
| 97 | Ulcerative colitis | 30.613 |
| 2 | Amyotrophic lateral sclerosis | 30.307 |
| 156 | Rett syndrome | 27.971 |
| 8 | Huntington disease | 27.657 |
| 17 | Multiple system atrophy | 27.605 |
| 3 | Spinal muscular atrophy | 26.997 |
| 5 | Progressive supranuclear palsy | 24.615 |
| 140 | Dorabe syndrome | 20.969 |
| 144 | Lennox-Gastaut syndrome | 20.847 |
| 205 | Fragile X syndrome related disease | 20.651 |
| 193 | Prader-Willi syndrome | 19.336 |
| 96 | Crohn disease | 19.185 |
| 46 | Malignant rheumatoid arthritis | 19.023 |
| 21 | Mitochondrial disease | 17.258 |
| 152 | PCDH19 related syndrome | 16.000 |
| 70 | Spinal stenosis | 15.674 |
| 84 | Sarcoidosis | 14.909 |
| 145 | West syndrome | 14.400 |
| 203 | 22q11.2 deletion syndrome | 14.000 |
| 296 | Biliary atresia | 13.827 |
| 201 | Angelman syndrome | 13.188 |
| 98 | Eosinophilic gastro-intestinal disorder | 13.109 |
| 22 | Moyamoya disease | 12.844 |
| 158 | Tuberous sclerosis | 12.754 |
| 34 | Neurofibromatosis | 12.503 |
| 272 | Fibrodysplasia ossificans progressiva | 12.034 |
| 298 | Hereditary pancreatitis | 11.958 |
| 155 | Acquired aphasia with convulsive disorder | 11.378 |
| 36 | Epidermolysis bullosa | 11.167 |
| 231 | Alpha-1-antitrypsin deficiency | 10.403 |
| 75 | Cushing disease | 10.335 |
| 85 | Idiopathic interstitial pneumonia | 3.612 |
| 113 | Muscular dystrophy | 3.540 |
| 49 | Systemic lupus erythematosus | 3.491 |
| 78 | Hypopituitarism | 2.618 |
| 127 | Frontotemporal lobar degeneration | 2.123 |
| 120 | Hereditary dystonia | 2.000 |
| 215 | Tetralogy of Fallot | 1.790 |
| 4 | Primary lateral sclerosis | 1.725 |
| 65 | Primary immunodeficiency | 1.549 |
| 299 | Cystic fibrosis | 1.520 |
| 171 | Wilson disease | 1.363 |
| 179 | Williams syndrome | 1.133 |
| 235 | Hypoparathyroidism | 1.044 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |