18. Spinocerebellar degeneration Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 76 / Drugs : 98 - (DrugBank : 31) / Drug target genes : 44 - Drug target pathways : 65
Spinocerebellar degeneration and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
18 | Spinocerebellar degeneration | - |
13 | Multiple sclerosis/Neuromyelitis optica | 39.642 |
6 | Parkinson disease | 36.501 |
206 | Fragile X syndrome | 33.600 |
97 | Ulcerative colitis | 30.613 |
2 | Amyotrophic lateral sclerosis | 30.307 |
156 | Rett syndrome | 27.971 |
8 | Huntington disease | 27.657 |
17 | Multiple system atrophy | 27.605 |
3 | Spinal muscular atrophy | 26.997 |
5 | Progressive supranuclear palsy | 24.615 |
140 | Dorabe syndrome | 20.969 |
144 | Lennox-Gastaut syndrome | 20.847 |
205 | Fragile X syndrome related disease | 20.651 |
193 | Prader-Willi syndrome | 19.336 |
96 | Crohn disease | 19.185 |
46 | Malignant rheumatoid arthritis | 19.023 |
21 | Mitochondrial disease | 17.258 |
152 | PCDH19 related syndrome | 16.000 |
70 | Spinal stenosis | 15.674 |
84 | Sarcoidosis | 14.909 |
145 | West syndrome | 14.400 |
203 | 22q11.2 deletion syndrome | 14.000 |
296 | Biliary atresia | 13.827 |
201 | Angelman syndrome | 13.188 |
98 | Eosinophilic gastrointestinal disease | 13.109 |
22 | Moyamoya disease | 12.844 |
158 | Tuberous sclerosis | 12.754 |
34 | Neurofibromatosis | 12.503 |
272 | Fibrodysplasia ossificans progressiva | 12.034 |
298 | Hereditary pancreatitis | 11.958 |
155 | Acquired aphasia with convulsive disorder | 11.378 |
36 | Epidermolysis bullosa | 11.167 |
231 | Alpha-1-antitrypsin deficiency | 10.403 |
75 | Cushing disease | 10.335 |
85 | Idiopathic interstitial pneumonia | 3.612 |
113 | Muscular dystrophy | 3.540 |
49 | Systemic lupus erythematosus | 3.491 |
78 | Hypopituitarism | 2.618 |
127 | Frontotemporal lobar degeneration | 2.123 |
120 | Hereditary dystonia | 2.000 |
215 | Tetralogy of Fallot | 1.790 |
4 | Primary lateral sclerosis | 1.725 |
65 | Primary immunodeficiency | 1.549 |
299 | Cystic fibrosis | 1.520 |
171 | Wilson disease | 1.363 |
179 | Williams syndrome | 1.133 |
235 | Hypoparathyroidism | 1.044 |
220 | Rapidly progressive glomerulonephritis | 1.000 |
30 | Distal myopathy | 1.000 |