Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CACNA2D1 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [7] 6, 13, 18, 19, 70, 226, 298 💬
2 CACNA2D2 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [7] 6, 13, 18, 19, 70, 226, 298 💬
3 CACNA2D3 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [7] 6, 13, 18, 19, 70, 226, 298 💬
4 CACNA2D4 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [7] 6, 13, 18, 19, 70, 226, 298 💬
5 CHRNA4 💬 [5] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline [4] 6, 18, 53, 298 💬
6 CHRNA4 💬 [5] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline tartrate 💬 Varenicline [4] 6, 18, 53, 298 💬
7 CHRNB2 💬 [5] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline tartrate 💬 Varenicline [4] 6, 18, 53, 298 💬
8 CHRNB2 💬 [5] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline [4] 6, 18, 53, 298 💬
9 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Lenograstim 💬 Lenograstim [8] 2, 13, 16, 18, 19, 57, 65, 97 💬
10 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin alfa 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
11 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin theta 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
12 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin epsilon 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
13 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin zeta 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
14 GABBR1 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
15 GABBR2 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
16 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
17 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
18 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
19 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
20 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
21 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
22 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
23 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
24 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
25 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
26 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
27 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
28 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
29 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
30 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
31 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
32 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Troriluzole 💬 Troriluzole [1] 18 💬
33 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
34 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
35 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
36 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
37 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Troriluzole 💬 Troriluzole [1] 18 💬
38 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
39 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Troriluzole 💬 Troriluzole [1] 18 💬
40 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
41 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
42 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Troriluzole 💬 Troriluzole [1] 18 💬
43 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
44 GRIK1 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
45 GRIK1 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
46 GRIK1 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole 💬 Troriluzole [1] 18 💬
47 GRIK2 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
48 GRIK2 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole 💬 Troriluzole [1] 18 💬
49 GRIK2 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
50 GRIK3 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole 💬 Troriluzole [1] 18 💬
51 GRIK3 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
52 GRIK3 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
53 GRIK4 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
54 GRIK4 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
55 GRIK4 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole 💬 Troriluzole [1] 18 💬
56 GRIK5 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
57 GRIK5 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole 💬 Troriluzole [1] 18 💬
58 GRIK5 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
59 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
60 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
61 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Troriluzole 💬 Troriluzole [1] 18 💬
62 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
63 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Troriluzole 💬 Troriluzole [1] 18 💬
64 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
65 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
66 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Troriluzole 💬 Troriluzole [1] 18 💬
67 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
68 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
69 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
70 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Troriluzole 💬 Troriluzole [1] 18 💬
71 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Troriluzole 💬 Troriluzole [1] 18 💬
72 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
73 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
74 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin 💬 Rosuvastatin [16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
75 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin calcium 💬 Rosuvastatin [16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
76 IFNGR1 💬 [18] Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differentiation, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Chagas disease, Toxoplasmosis, Tuberculosis, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
77 IFNGR2 💬 [17] Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differentiation, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Chagas disease, Toxoplasmosis, Tuberculosis, Influenza A, Herpes simplex virus 1 infection, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
78 NFE2L2 💬 [7] Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Omaveloxolone 💬 Omaveloxolone [1] 18 💬
79 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone acetate 💬 Methylprednisolone [51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
80 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone [51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
81 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone [58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
82 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone [48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
83 SLC6A1 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, GABAergic synapse Gabapentin 💬 Gabapentin [7] 6, 13, 18, 19, 70, 226, 298 💬
84 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrobromide 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
85 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
86 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrochloride 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
87 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrobromide 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
88 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrochloride 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
89 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
90 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Citalopram hydrobromide 💬 Citalopram [7] 6, 8, 13, 18, 46, 98, 127 💬
91 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Citalopram 💬 Citalopram [7] 6, 8, 13, 18, 46, 98, 127 💬
92 VDR 💬 [5] Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Calcitriol 💬 Calcitriol [11] 18, 37, 46, 49, 66, 96, 158, 223, 235, 238, 326 💬