Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Artesunate [1] Artesunate[1] Artesunate 💬 --[4] 18, 66, 86, 96 💬
2 Baclofen [1] Baclofen[1] Baclofen 💬 [2] GABBR1,
GABBR2 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206 💬
3 Bupropion [2] Bupropion; Bupropion Hydrochloride[3] Bupropion hydrochloride ,
Bupropion ,
Bupropion hydrobromide 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
4 Calcitriol [1] Calcitriol[1] Calcitriol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[11] 18, 37, 46, 49, 66, 96, 158, 223, 235, 238, 326 💬
5 Citalopram [1] Citalopram[2] Citalopram hydrobromide ,
Citalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
6 Deferiprone [1] DEFERIPRONE[1] Deferiprone 💬 --[7] 2, 6, 18, 121, 122, 139, 233 💬
7 Elamipretide [1] Elamipretide[2] Elamipretide ,
Elamipretide hydrochloride 💬 		--[3] 18, 21, 324 💬
8 Erythropoietin [3] EPOETIN ALFA; Erythropoietin; RhEPO[4] Epoetin alfa ,
Epoetin epsilon ,
Epoetin theta ,
Epoetin zeta 💬 		[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
9 Etravirine [2] ETRAVIRINA; Etravirine[1] Etravirine 💬 --[1] 18 💬
10 Flumazenil [1] Flumazenil[1] Flumazenil 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
11 Fursultiamine [1] Fursultiamine[2] Fursultiamine ,
Fursultiamine hydrochloride 💬 		--[2] 6, 18 💬
12 Gabapentin [3] GABAPENTIN; GABAPENTINA; Gabapentine[1] Gabapentin 💬 [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[10] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[7] 6, 13, 18, 19, 70, 226, 298 💬
13 Ginkgo biloba [1] Ginkgo biloba[1] Ginkgo 💬 --[4] 13, 18, 47, 90 💬
14 Idebenone [1] Idebenone[1] Idebenone 💬 --[9] 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
15 Interferon Gamma [1] Interferon Gamma---[9] 18, 65, 85, 96, 107, 228, 299, 301, 326 💬
16 Interferon gamma-1b [1] Interferon gamma-1b[1] Interferon gamma-1b 💬 [2] IFNGR1,
IFNGR2 💬 		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
17 Iron [1] Iron[1] Ferrous fumarate 💬 --[7] 18, 60, 96, 97, 238, 254, 284 💬
18 Lenograstim [2] G-CSF; Lenograstim[1] Lenograstim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[8] 2, 13, 16, 18, 19, 57, 65, 97 💬
19 Leucine [2] L-leucine; Leucine[1] Leucine 💬 --[13] 5, 6, 7, 18, 19, 65, 96, 97, 127, 280, 283, 284, 299 💬
20 Lithium carbonate [1] LITHIUM CARBONATE[1] Lithium carbonate 💬 --[6] 2, 13, 17, 18, 127, 310 💬
21 LX2006 [1] LX2006---[1] 18 💬
22 Methylprednisolone [3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
23 Nerve Growth Factor [1] Nerve Growth Factor---[5] 2, 3, 18, 53, 90 💬
24 Nicotinamide [2] Niacinamide; Nicotinamide[1] Niacinamide 💬 --[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
25 Nicotinamide riboside [2] Nicotinamide riboside; Nicotinamide Riboside Chloride---[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
26 Nomlabofusp [2] CTI-1601; Nomlabofusp---[1] 18 💬
27 Omaveloxolone [1] Omaveloxolone[1] Omaveloxolone 💬 [1] NFE2L2 💬 [7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
28 Phenylbutyric acid [2] PHENYLBUTYRATE; Sodium phenylbutyrate[1] Sodium phenylbutyrate 💬 --[5] 2, 3, 8, 18, 251 💬
29 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
30 Prednisone [2] Prednisona; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
31 Resveratrol [2] Resveratrol; Trans-Resveratrol---[10] 2, 6, 8, 18, 46, 57, 89, 97, 113, 299 💬
32 Riluzole [1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
33 Rosuvastatin [2] Rosuvastatin; Rosuvastatin calcium[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
34 Taltirelin [1] Taltirelin---[1] 18 💬
35 Tocotrienol [1] Tocotrienol---[4] 18, 21, 156, 299 💬
36 Trehalose [2] Cabaletta; Trehalose---[4] 2, 6, 18, 113 💬
37 Troriluzole [1] Troriluzole[2] Troriluzole ,
Troriluzole hydrochloride 💬 		[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[1] 18 💬
38 Varenicline [2] VARENICLINE; VARENICLINE TARTRATE[2] Varenicline tartrate ,
Varenicline 💬 		[2] CHRNA4,
CHRNB2 💬 		[5] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[4] 6, 18, 53, 298 💬
39 Vatiquinone [2] Alpha-tocotrienol quinone; VATIQUINONE[1] Vatiquinone 💬 --[2] 18, 21 💬
40 VO659 [1] VO659---[2] 8, 18 💬