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DR info

Clinical trials : 525 / Drugs : 330 - (DrugBank : 49) / Drug target genes : 20 - Drug target pathways : 59

Drugs, Primary sponsors and Trial info (Enrollment year, Phase, Trial ID, Countries)

0.9% nacl
   Arrowhead Pharmaceuticals
      2019   Phase 1   NCT03747224   Australia;New Zealand
   Visirna Therapeutics HK Limited
      2023   Phase 1   NCT05851066   China
2-[3,5-dichloro-4-(5-isopropyl-6-OXO-1,6-dihydro-pyridazin-3-yloxy)- phenyl]-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carbonitrile
   Madrigal Pharmaceuticals, Inc.
      2017   Phase 2   EUCTR2016-002315-17-NO   Denmark;Netherlands;Norway
      2017   Phase 2   EUCTR2016-002315-17-NL   Denmark;Netherlands;Norway
      2017   Phase 2   EUCTR2016-002315-17-DK   Denmark;Netherlands;Norway
2-hydroxybenzylamine
   Vanderbilt University Medical Center
      2024   Phase 2   NCT04941599   United States
AAV directed hldlr gene therapy
   Regenxbio Inc.
      2016   Phase 1/Phase 2   NCT02651675   Canada;Italy;Netherlands;United States
AAV8.TBG.hldlr
   REGENXBIO Inc.
      2020   Phase 2   EUCTR2019-004496-39-NL   Canada;Italy;Netherlands;United States
      2017   Phase 1;Phase 2   EUCTR2016-001446-25-IT   Canada;Italy;Netherlands;United States
   University of Pennsylvania
      2017   Phase 1;Phase 2   EUCTR2016-001446-25-NL   Canada;Italy;Netherlands;United States
AEGR-733
   AEGERION PHARMACEUTICALS
      2011   -   EUCTR2010-023742-79-IT   Italy
   Aegerion Pharmaceuticals
      2009   -   EUCTR2008-007058-36-IT   Italy
   Aegerion Pharmaceuticals Inc.
      2016   Phase 3   EUCTR2014-003806-33-GR   Austria;Canada;Germany;Greece;Israel;Italy;Turkey
   Aegerion Pharmaceuticals, Inc.
      2007   Phase 3   NCT00730236   Canada;Italy;South Africa;United States
AK102
   Akeso
      2019   Phase 2   NCT04173793   China
      2019   Phase 2   NCT03933293   China
Akcea-angptl3-LRX
   Akcea Therapeutics
      2018   Phase 2   NCT03455777   Canada
Alirocumab
   Fundación Hipercolesterolemia Familiar
      2018   Phase 4   EUCTR2017-004299-69-ES   Spain
   REGENERON PHARMACEUTICALS, INC.
      2019   Phase 3   EUCTR2017-003170-13-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-001388-19-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      2017   Phase 3   EUCTR2017-000351-95-IT   Austria;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals
      2017   Phase 3   NCT03156621   Austria;Canada;Czechia;France;Germany;Greece;Italy;Japan;South Africa;Taiwan;Turkey;Ukraine;United States
      2016   Phase 4   NCT02957682   Bulgaria;Chile;Colombia;Estonia;Japan;Mexico;Russian Federation;South Africa;Ukraine;United States
      2015   Phase 3   NCT02326220   Germany;United States
      2012   Phase 3   NCT01709500   Czech Republic;Netherlands;Norway;United Kingdom
      2012   Phase 2   NCT01576484   Canada;United States
      2011   Phase 2   NCT01266876   Canada;Netherlands;United States
   Regeneron Pharmaceuticals Inc.
      2018   Phase 3   EUCTR2017-001388-19-GR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-DE   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      2012   -   EUCTR2012-001222-95-NL   Czech Republic;Netherlands;United Kingdom
      2012   -   EUCTR2012-001222-95-GB   Czech Republic;Netherlands;United Kingdom
      2012   -   EUCTR2012-001222-95-CZ   Czech Republic;Netherlands;United Kingdom
      -   Phase 3   EUCTR2017-001388-19-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      -   Phase 3   EUCTR2017-001388-19-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals, Inc.
      2019   Phase 4   EUCTR2018-002810-11-BG   Bulgaria;Chile;Estonia;Mexico;Russian Federation;South Africa;Ukraine;United States
      2019   Phase 3   EUCTR2017-003170-13-GR   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 4   EUCTR2018-002810-11-EE   Bulgaria;Chile;Estonia;Mexico;Russian Federation;South Africa;Ukraine;United States
      2018   Phase 3   EUCTR2017-003170-13-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2017-000351-95-GR   Austria;Canada;Czech Republic;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
      2017   Phase 3   EUCTR2017-000351-95-FR   Austria;Belgium;Bulgaria;Canada;Croatia;Czech Republic;Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Poland;Portugal;Serbia;Slovenia;South Africa;Spain;Sweden;Tunisia;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2017-000351-95-DE   Austria;Canada;Czech Republic;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
      2017   Phase 3   EUCTR2017-000351-95-AT   Austria;Canada;Czech Republic;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
      2017   Phase 4   EUCTR2016-003189-16-SK   Argentina;Bulgaria;Chile;Colombia;Estonia;Israel;Japan;Mexico;Peru;Russian Federation;Slovakia;South Africa;Ukraine;United States
      2017   Phase 4   EUCTR2016-003189-16-BG   Argentina;Bulgaria;Chile;Colombia;Czech Republic;Denmark;Estonia;Germany;Hungary;Israel;Japan;Mexico;Netherlands;Poland;Romania;Russian Federation;Slovakia;South Africa;United Kingdom;United States
      2016   Phase 4   EUCTR2016-003189-16-EE   Argentina;Bulgaria;Chile;Colombia;Estonia;Israel;Japan;Mexico;Peru;Russian Federation;Slovakia;South Africa;Ukraine;United States
      2015   Phase 3   EUCTR2014-001917-20-DE   Germany;United States
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-GB   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002333-11-DE   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      -   Phase 3   EUCTR2017-003170-13-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
      -   Phase 3   EUCTR2017-000351-95-CZ   Austria;Belgium;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Israel;Italy;Netherlands;Poland;Portugal;Serbia;Slovenia;South Africa;Spain;Sweden;Tunisia;Turkey;Ukraine;United Kingdom;United States
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
      2014   Phase 3   NCT02107898   Japan
      2013   Phase 3   NCT01954394   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   Phase 3   NCT01623115   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   Phase 3   NCT01617655   Canada;Netherlands;Russian Federation;South Africa;United States
   Sanofi-Aventis Recherche & Développement
      2018   Phase 3   EUCTR2017-002297-39-SI   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-NO   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-NL   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-IT   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-FR   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-ES   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-DK   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-BG   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-AT   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
   Sanofi-aventis recherche & développement
      2018   Phase 3   EUCTR2017-001903-60-SI   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-SE   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-NO   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-NL   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-IT   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-HU   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-FR   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-FI   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-ES   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-DK   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-DE   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-CZ   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-BG   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-AT   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      -   Phase 3   EUCTR2017-001903-60-PL   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
   sanofi-aventis recherche et développement
      2014   Phase 3   EUCTR2013-002572-40-RO   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-PT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-NO   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-HU   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-GB   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-FI   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DK   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-CZ   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BG   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-AT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-NL   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-IT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-ES   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
   sanofi-aventis recherche&developpement
      2017   Phase 2   EUCTR2015-003766-85-SE   Australia;Canada;Czech Republic;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden
      2016   Phase 2   EUCTR2015-003766-85-FR   Australia;Canada;Czech Republic;France;Israel;Norway;Russian Federation;Spain;Sweden
      2016   Phase 2   EUCTR2015-003766-85-ES   Australia;Canada;Czech Republic;France;Israel;Norway;Russian Federation;Spain;Sweden
      2016   Phase 2   EUCTR2015-003766-85-CZ   Australia;Canada;Czech Republic;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden
      -   Phase 2   EUCTR2015-003766-85-Outside-EU/EEA   Australia;Canada;Czech Republic;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden
ALN-60212
   The Medicines Company
      2018   Phase 3   EUCTR2017-002472-30-GB   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-SE   Canada;Czech Republic;Denmark;Israel;Netherlands;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-ES   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-DK   Canada;Czech Republic;Denmark;Netherlands;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-CZ   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 2   EUCTR2016-003376-49-NL   Netherlands;South Africa;United States
ALN-pcssc
   The Medicines Company
      2017   Phase 2   EUCTR2016-003376-49-NL   Netherlands;South Africa;United States
      2016   Phase 2   NCT02963311   Netherlands;South Africa;United States
      2016   Phase 2   NCT02597127   Canada;Germany;Netherlands;United Kingdom;United States
AMG 145
   AMGEN INC.
      2016   Phase 3   EUCTR2015-002276-25-IT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
   Amgen Europe B.V.
      2019   Phase 3   EUCTR2015-002276-25-SI   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Swaziland;Switzerland;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Amgen Inc
      2019   Phase 3   EUCTR2015-002276-25-PT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2019   Phase 3   EUCTR2015-002276-25-PL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2014-002277-11-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2014-002277-11-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2014-002277-11-SI   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-002276-25-NL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2017   Phase 3   EUCTR2015-002276-25-ES   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-HU   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-GR   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-DE   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-CZ   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-BE   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-AT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2016   Phase 3   EUCTR2014-002277-11-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-002277-11-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   -   EUCTR2014-002277-11-HU   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Finland;Hungary;Italy;New Zealand;South Africa;Spain;Turkey;United States
      2016   Phase 3   EUCTR2014-002277-11-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   -   EUCTR2014-002277-11-FI   Australia;Belgium;Brazil;Canada;Czech Republic;Finland;New Zealand;South Africa;Spain;Turkey;United States
      2016   Phase 3   EUCTR2014-002277-11-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-002277-11-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-002277-11-NO   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2015   -   EUCTR2014-002277-11-ES   Australia;Brazil;Canada;New Zealand;South Africa;Spain;Turkey;United States
      2015   Phase 3   EUCTR2014-002277-11-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2   EUCTR2011-005400-15-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Malaysia;Netherlands;New Zealand;Norway;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2   EUCTR2011-005400-15-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Malaysia;Netherlands;New Zealand;Norway;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Netherlands;New Zealand;South Africa;Spain;United Kingdom;United States
      2013   -   EUCTR2011-005400-15-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Malaysia;New Zealand;Norway;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2013   -   EUCTR2011-005399-40-NL   Belgium;Brazil;Canada;Czech Republic;France;Hong Kong;Italy;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United States
      2013   -   EUCTR2011-005399-40-IT   Austria;Belgium;Brazil;Canada;Czech Republic;France;Hong Kong;Italy;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United States
      2013   -   EUCTR2011-005399-40-ES   Austria;Belgium;Brazil;Canada;Czech Republic;France;Hong Kong;Malaysia;New Zealand;South Africa;Spain;Turkey;United States
      2013   Phase 2;Phase 3   EUCTR2011-005399-40-CZ   Belgium;Brazil;Canada;Czech Republic;France;Hong Kong;Italy;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United States
      2012   -   EUCTR2012-001365-32-SE   Australia;Canada;France;Germany;Hong Kong;Japan;Netherlands;New Zealand;Norway;Singapore;South Africa;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 3   EUCTR2012-001365-32-NL   Australia;Canada;France;Germany;Hong Kong;Japan;Netherlands;New Zealand;Norway;Singapore;South Africa;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 3   EUCTR2012-001365-32-GB   Australia;Canada;France;Germany;Hong Kong;Japan;Netherlands;New Zealand;Norway;Singapore;South Africa;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 3   EUCTR2012-001365-32-ES   Australia;Canada;France;Germany;Hong Kong;Japan;Netherlands;New Zealand;Norway;Singapore;South Africa;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   -   EUCTR2012-001365-32-DE   Australia;Canada;France;Germany;Hong Kong;Japan;Netherlands;New Zealand;Norway;Singapore;South Africa;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 2   EUCTR2011-005400-15-GR   Belgium;Canada;Czech Republic;Greece;Italy;Netherlands;South Africa;Spain;United Kingdom;United States
      2012   Phase 2;Phase 3   EUCTR2011-005400-15-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2012   Phase 2;Phase 3   EUCTR2011-005399-40-BE   Belgium;Brazil;Canada;Czech Republic;France;Hong Kong;Italy;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United States
      2012   Phase 2   EUCTR2011-001915-29-DE   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Japan;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-SE   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-NO   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-NL   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-HU   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-GB   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-FI   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-ES   Australia;Belgium;Canada;Czech Republic;Denmark;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-DK   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-CZ   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Japan;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-BE   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   -   EUCTR2011-001528-39-SE   Canada;Germany;Hong Kong;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   -   EUCTR2011-001528-39-GB   Canada;Germany;Hong Kong;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   -   EUCTR2011-001528-39-ES   Canada;Germany;Hong Kong;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   -   EUCTR2011-001528-39-DE   Canada;Germany;Hong Kong;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      -   Phase 3   EUCTR2015-002276-25-NO   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2015-002276-25-GB   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;United Kingdom
      -   -   EUCTR2014-002277-11-Outside-EU/EEA   Australia;Brazil;Canada;New Zealand;South Africa;Turkey;United States
      -   Phase 3   EUCTR2014-002277-11-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      -   -   EUCTR2011-005399-40-Outside-EU/EEA   Brazil;Canada;Hong Kong;Lebanon;Malaysia;New Zealand;South Africa;Turkey;United States
AMG145
   AMGEN INC.
      2016   Phase 3   EUCTR2015-002276-25-IT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
   Amgen Inc
      2019   Phase 3   EUCTR2014-002277-11-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2014-002277-11-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2014-002277-11-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-002277-11-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   -   EUCTR2014-002277-11-HU   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Finland;Hungary;Italy;New Zealand;South Africa;Spain;Turkey;United States
      2016   Phase 3   EUCTR2014-002277-11-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   -   EUCTR2014-002277-11-FI   Australia;Belgium;Brazil;Canada;Czech Republic;Finland;New Zealand;South Africa;Spain;Turkey;United States
      2016   Phase 3   EUCTR2014-002277-11-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-002277-11-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-002277-11-NO   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2015   -   EUCTR2014-002277-11-ES   Australia;Brazil;Canada;New Zealand;South Africa;Spain;Turkey;United States
      2015   Phase 3   EUCTR2014-002277-11-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Netherlands;New Zealand;South Africa;Spain;United Kingdom;United States
      2012   Phase 2;Phase 3   EUCTR2011-005400-15-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Malaysia;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      -   -   EUCTR2014-002277-11-Outside-EU/EEA   Australia;Brazil;Canada;New Zealand;South Africa;Turkey;United States
      -   Phase 3   EUCTR2014-002277-11-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
Amlodipine/atorvastatin
   Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
      2010   -   NCT01107743   -
Anacetrapib
   Merck Sharp & Dohme Corp.
      2013   Phase 3   NCT01841684   Canada;Germany;Israel;Italy;Norway;United Kingdom;United States
      2013   Phase 3   NCT01824238   Japan
      2012   Phase 3   NCT01524289   Canada;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
      2013   Phase 3   EUCTR2012-002434-37-IT   Brazil;Canada;Czech Republic;Israel;Italy;Malaysia;Norway;South Africa;United Kingdom;United States
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
      2012   Phase 3   EUCTR2011-004525-27-NL   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   Phase 3   EUCTR2011-004525-27-GB   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   Phase 3   EUCTR2011-004525-27-ES   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   Phase 3   EUCTR2011-004525-27-DE   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   -   EUCTR2011-004525-27-CZ   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
APL180
   Novartis Pharma Services AG
      2008   -   EUCTR2008-002848-41-NL   Netherlands
   Novartis Pharmaceuticals
      2006   Phase 2   NCT00751608   Netherlands
ARO-ANG 3 injection
   Arrowhead Pharmaceuticals
      2022   Phase 2   NCT05217667   Australia;Canada;South Africa;United States
ARO-ANG3
   Arrowhead Pharmaceuticals
      2019   Phase 1   NCT03747224   Australia;New Zealand
ART002g1 injection
   Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
      2026   Early Phase 1   NCT07353398   China
Atorvastatin
   Organon and Co
      2000   Phase 3   NCT03885921   -
      2000   Phase 3   NCT03884452   -
   Pfizer
      2008   Phase 1   NCT00739999   Canada;Greece;Norway
   Pfizer Inc
      2009   Phase 3   EUCTR2008-006130-95-SK   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
      2009   -   EUCTR2008-006130-95-IT   Belgium;Germany;Hungary;Italy;Spain
      2009   -   EUCTR2008-006130-95-HU   Belgium;Germany;Hungary;Italy;Spain
      2009   -   EUCTR2008-006130-95-GR   Belgium;Germany;Greece;Hungary;Italy;Spain
      2009   Phase 3   EUCTR2008-006130-95-BE   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
      -   -   EUCTR2008-006130-95-Outside-EU/EEA   Canada;Russian Federation;Turkey;United States
   Pfizer Inc, 235 East 42nd Street, New York, NY 10017
      -   -   EUCTR2008-002774-34-Outside-EU/EEA   Canada
   Pfizer Inc,235 East 42nd Street,New York,NY 10017
      -   -   EUCTR2008-002774-34-NL   Netherlands
   Pfizer Inc. 235 East 42nd Street, New York, NY 10017, USA
      2009   -   EUCTR2008-006130-95-DE   Belgium;Canada;Germany;Greece;Hungary;Italy;Norway;Poland;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United States
   Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
      2009   Phase 3   NCT00827606   Belgium;Canada;Germany;Greece;Hungary;Italy;Norway;Poland;Puerto Rico;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United States
   Regeneron Pharmaceuticals
      2012   Phase 3   NCT01709500   Czech Republic;Netherlands;Norway;United Kingdom
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
   Universitätsklinikum Freiburg
      -   Phase 4   EUCTR2014-005473-36-DE   Germany
Atorvastatin ,zarator
   Pfizer
      2005   Phase 3   EUCTR2004-004269-14-IS   Denmark;Iceland;Sweden
Atorvastatin calcium
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
Atorvastatin/ zarator
   Pfizer
      2005   Phase 3   EUCTR2004-004269-14-IS   Denmark;Iceland;Sweden
Atorvastatina calcica trihidrato
   PFIZER
      2009   Phase 3   EUCTR2008-006130-95-ES   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
AZD0780
   AstraZeneca
      2025   Phase 3   NCT07000136   Argentina;Australia;Brazil;Bulgaria;Canada;Chile;Czechia;Denmark;Finland;France;Germany;Hungary;Japan;Netherlands;New Zealand;Norway;Poland;Slovakia;South Africa;South Korea;Spain;Sweden;Taiwan;Turkey (Türkiye);United States;Vietnam
AZD4522
   AstraZeneca AB
      2010   -   EUCTR2009-016492-29-NL   Belgium;Canada;Netherlands;Norway;United States
      2010   Phase 3   EUCTR2009-016492-29-BE   Belgium;Netherlands
      2010   -   EUCTR2009-016492-29-AT   Austria;Belgium;Netherlands
      2006   Phase 3   EUCTR2006-002616-96-NL   Netherlands;Spain
      -   -   EUCTR2009-016492-29-Outside-EU/EEA   Belgium;Canada;Netherlands;Norway;United States
      -   -   EUCTR2006-002616-96-Outside-EU/EEA   Canada;United States
Bempedoic acid
   A. Menarini International Licensing S.A.
      2026   Phase 3   NCT07614958   United Kingdom
   Esperion Therapeutics, Inc.
      2023   Phase 2   NCT05694260   Canada;Denmark;Germany;Netherlands;Spain;United States
      2023   Phase 2   EUCTR2018-004084-31-NL   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2018-004084-31-ES   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2018-004084-31-DE   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-NL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
Bempedoic acid 180MG tablets
   Esperion Therapeutics, Inc.
      2017   Phase 3   EUCTR2016-004115-12-PL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-NL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-GB   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-DE   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-PL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-GB   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-DE   Canada;Germany;Netherlands;Poland;United Kingdom;United States
Blood sample
   Centre Hospitalier Universitaire, Amiens
      2025   -   NCT06555120   France
Blood test
   Hospices Civils de Lyon
      2022   -   NCT05191355   France
      2020   -   NCT04261803   France
BMS356384
   Karo Bio AB
      2011   -   EUCTR2011-001483-21-SE   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-GB   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-ES   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   Phase 3   EUCTR2011-001483-21-DK   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-CZ   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-AT   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
Bococizumab (PF-04950615
   Pfizer
      2013   Phase 3   NCT01968980   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
Calcium
   PFIZER
      2009   Phase 3   EUCTR2008-006130-95-ES   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
   Pfizer Inc
      2009   Phase 3   EUCTR2008-006130-95-SK   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
      2009   -   EUCTR2008-006130-95-HU   Belgium;Germany;Hungary;Italy;Spain
      2009   -   EUCTR2008-006130-95-GR   Belgium;Germany;Greece;Hungary;Italy;Spain
      2009   Phase 3   EUCTR2008-006130-95-BE   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
      -   -   EUCTR2008-006130-95-Outside-EU/EEA   Canada;Russian Federation;Turkey;United States
   Pfizer Inc, 235 East 42nd Street, New York, NY 10017
      -   -   EUCTR2008-002774-34-Outside-EU/EEA   Canada
   Pfizer Inc. 235 East 42nd Street, New York, NY 10017, USA
      2009   -   EUCTR2008-006130-95-DE   Belgium;Canada;Germany;Greece;Hungary;Italy;Norway;Poland;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United States
Cardyl 10 MG comprimidos recubiertos CON PELícula
   PFIZER
      2009   Phase 3   EUCTR2008-006130-95-ES   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
Cardyl 20 MG comprimidos recubiertos CON PELícula
   PFIZER
      2009   Phase 3   EUCTR2008-006130-95-ES   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
Cardyl 40 MG comprimidos recubiertos CON PELícula
   PFIZER
      2009   Phase 3   EUCTR2008-006130-95-ES   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
Cascade
   Isfahan University of Medical Sciences
      2016   -   NCT02865694   Iran, Islamic Republic of
Cascade screening
   Northwestern University
      2023   -   NCT05750667   United States
      2022   -   NCT05430191   United States
Cascade testing
   Mayo Clinic
      2026   -   NCT07653555   United States
CER-001
   CERENIS THERAPEUTICS SA
      2012   -   EUCTR2011-003998-28-IT   Canada;Italy;Netherlands;United Kingdom;United States
   Cerenis Therapeutics
      2012   -   EUCTR2011-003998-28-NL   Canada;France;Italy;Netherlands;United Kingdom;United States
      2012   Phase 2   EUCTR2011-003998-28-GB   Canada;Italy;Netherlands;United Kingdom;United States
   Cerenis Therapeutics, SA
      2012   Phase 2   NCT01515241   Canada
      2011   Phase 2   NCT01412034   Canada;Italy;Netherlands;United Kingdom;United States
Cholestagel
   Daiichi Sankyo Pharma Development
      2007   -   EUCTR2005-003511-75-CZ   Czech Republic;Hungary
      2006   Phase 4   EUCTR2005-003511-75-SK   Austria;Czech Republic;Hungary;Slovakia
      2006   -   EUCTR2005-003511-75-HU   Czech Republic;Hungary
   Genzyme Europe BV
      2007   -   EUCTR2007-000582-37-SE   France;Germany;Sweden;United Kingdom
      2007   Phase 4   EUCTR2007-000582-37-GB   France;Germany;Sweden;United Kingdom
      2007   Phase 4   EUCTR2007-000582-37-FR   France;Germany;Sweden;United Kingdom
      2007   -   EUCTR2007-000582-37-DE   France;Germany;Sweden;United Kingdom
Cholesterol
   Tada Hayato
      2025   -   JPRN-jRCT1040250123   -
Cholestyramine
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
CION-08 concentration unit: MG milligram(S)concentration type: equalconcentration number: 90-trade name: nilemdo product name: bempedoic acidpharmaceutical form: tabletinn or proposed INN: bempedoic acidcas number: 738606-46-7 current sponsor code: ETC-1002
   Esperion Therapeutics, Inc.
      2022   Phase 2   EUCTR2018-004084-31-DK   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
Colesevelam HCL
   Daiichi Sankyo Pharma Development
      2007   -   EUCTR2005-003511-75-CZ   Czech Republic;Hungary
      2006   Phase 4   EUCTR2005-003511-75-SK   Austria;Czech Republic;Hungary;Slovakia
      2006   -   EUCTR2005-003511-75-HU   Czech Republic;Hungary
   Daiichi Sankyo, Inc.
      2005   Phase 4   NCT00145574   Australia;Austria;Canada;Israel;Netherlands;Norway;South Africa;United States
   Sankyo Pharma Development (SPhD)
      2005   -   EUCTR2005-003511-75-AT   Austria;Czech Republic;Hungary
      -   Phase 4   EUCTR2005-003511-75-NO   Austria;Czech Republic;Hungary;Norway;Slovakia
Colesevelam hydrochloride
   Genzyme Europe BV
      2007   -   EUCTR2007-000582-37-SE   France;Germany;Sweden;United Kingdom
      2007   Phase 4   EUCTR2007-000582-37-GB   France;Germany;Sweden;United Kingdom
      2007   Phase 4   EUCTR2007-000582-37-FR   France;Germany;Sweden;United Kingdom
      2007   -   EUCTR2007-000582-37-DE   France;Germany;Sweden;United Kingdom
Colesevelam hydrochloride FILM-coated tablets
   Genzyme, a Sanofi Company
      2007   Phase 4   NCT00655265   France;Germany;Netherlands;Sweden;United Kingdom
Combination therapy
   NewAmsterdam Pharma
      2024   Phase 3   NCT06005597   United States
Control - NO result
   Geisinger Clinic
      2020   Early Phase 1   NCT03832985   United States
CP-529,414/atorvastatin
      2005   -   EUCTR2004-004269-14-DK   Denmark;Iceland;Sweden
   Pfizer
      2005   Phase 3   EUCTR2004-004269-14-IS   Denmark;Iceland;Sweden
   Pfizer AB
      2005   -   EUCTR2004-004269-14-SE   Denmark;Iceland;Sweden
Crestor
   AstraZeneca AB
      2010   -   EUCTR2009-016492-29-NL   Belgium;Canada;Netherlands;Norway;United States
      2010   Phase 3   EUCTR2009-016492-29-BE   Belgium;Netherlands
      2010   -   EUCTR2009-016492-29-AT   Austria;Belgium;Netherlands
      -   -   EUCTR2009-016492-29-Outside-EU/EEA   Belgium;Canada;Netherlands;Norway;United States
      -   -   EUCTR2006-002616-96-Outside-EU/EEA   Canada;United States
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-GB   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-ES   Australia;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002333-11-DE   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
Crestor 10 MG encapsulated tablet
   AstraZeneca AB
      2006   Phase 3   EUCTR2006-002616-96-NL   Netherlands;Spain
Crestor 5 MG encapsulated tablet
   AstraZeneca AB
      2006   Phase 3   EUCTR2006-002616-96-NL   Netherlands;Spain
Crestor FILM-coated tablet
   AstraZeneca AB
      2015   Phase 3   EUCTR2014-004746-99-DK   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      2015   Phase 3   EUCTR2014-004746-99-BE   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      -   Phase 3   EUCTR2014-004746-99-SE   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
Crestor tablets (calcium rosuvastatin) FILM-coated tablets
   AstraZeneca AB
      2014   -   EUCTR2014-000972-24-SE   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
      2014   -   EUCTR2014-000972-24-NL   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
      2014   -   EUCTR2014-000972-24-DK   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      2014   -   EUCTR2014-000972-24-DE   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2014-000972-24-BE   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
CTX310
   CRISPR Therapeutics AG
      2024   Phase 1   NCT07491172   Australia;New Zealand;United Kingdom;United States
Dextran sulfate adsorption
   Laval University
      2013   -   NCT02286596   Canada
Direct contact OF family members FOR cascade screening OF relevant variants
   University of Maryland, Baltimore
      2023   -   NCT05348564   United States
Dppg
   Cerenis Therapeutics
      2012   Phase 2   EUCTR2011-003998-28-GB   Canada;Italy;Netherlands;United Kingdom;United States
EDP167
   Eddingpharm (Zhuhai) Co., Ltd.
      2026   Phase 2   NCT07489209   China
Enlicitide decanoate
   Merck Sharp & Dohme LLC
      2025   Phase 2/Phase 3   NCT07058077   Australia;Belgium;Brazil;Chile;China;Colombia;Finland;Germany;Netherlands;New Zealand;Singapore;Spain;United Kingdom;United States
      2023   Phase 3   NCT05952869   Australia;Brazil;Canada;Chile;Colombia;Czechia;Finland;Hong Kong;Hungary;Israel;Netherlands;New Zealand;Norway;Singapore;Spain;Taiwan;United States
      2023   Phase 3   NCT05952856   Argentina;China;Colombia;Germany;Israel;Italy;Japan;Mexico;South Africa;South Korea;Spain;Taiwan;Turkey (Türkiye);United States
Eprotirome
   Karo Bio AB
      2011   Phase 3   NCT01410383   Sweden
      2011   -   EUCTR2011-001483-21-SE   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-GB   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-ES   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   Phase 3   EUCTR2011-001483-21-DK   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-CZ   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-AT   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
ER niacin/laropiprant
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
      2012   -   EUCTR2012-001443-49-GB   New Zealand;Norway;South Africa;United Kingdom
ER-niacin or niacin
   Laboratoires Merck Sharp & Dohme - Chibret
      2007   Phase 3   EUCTR2006-001913-13-FR   France;Germany;Sweden;United Kingdom
   Merck & Co., Inc
      2007   -   EUCTR2006-001913-13-SE   France;Germany;Sweden;United Kingdom
   Merck & Co., Inc.
      2006   Phase 3   EUCTR2006-001913-13-DE   France;Germany;Sweden;United Kingdom
   Merck Sharp & Dohme Limited
      2007   Phase 3   EUCTR2006-001913-13-GB   France;Germany;Sweden;United Kingdom
ESP55016
   Esperion Therapeutics, Inc.
      2017   Phase 3   EUCTR2016-004115-12-PL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-NL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-GB   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-DE   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-PL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-NL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-GB   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-DE   Canada;Germany;Netherlands;Poland;United Kingdom;United States
ETC-1002
   Esperion Therapeutics, Inc.
      2023   Phase 2   EUCTR2018-004084-31-NL   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2018-004084-31-ES   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2018-004084-31-DE   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-PL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-NL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-GB   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004115-12-DE   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-PL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-GB   Canada;Germany;Netherlands;Poland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-004136-36-DE   Canada;Germany;Netherlands;Poland;United Kingdom;United States
ETC-1002 180MG tablets
   Esperion Therapeutics, Inc.
      2016   Phase 3   EUCTR2015-004136-36-NL   Canada;Germany;Netherlands;Poland;United Kingdom;United States
Evinacumab
   Daniel Gaudet
      2023   Phase 3   NCT05611528   Canada
   Makino Hisashi
      2023   Phase 3   JPRN-jRCT2051220184   -
   REGENERON PHARMACEUTICALS, INC.
      2019   Phase 3   EUCTR2017-003170-13-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-001388-19-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals
      2024   -   NCT06500598   -
      2020   Phase 3   NCT04233918   Australia;Austria;Netherlands;Taiwan;Ukraine;United States
      2018   Phase 3   NCT03409744   Australia;Austria;Canada;Czechia;France;Greece;Italy;Japan;Netherlands;Norway;South Africa;Ukraine;United States
      2018   Phase 3   NCT03399786   Australia;Austria;Canada;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals Inc.
      2018   Phase 3   EUCTR2017-001388-19-GR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-DE   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      -   Phase 3   EUCTR2017-001388-19-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      -   Phase 3   EUCTR2017-001388-19-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals, Inc.
      2020   Phase 1;Phase 3   EUCTR2019-001931-30-NL   Australia;Austria;Netherlands;Taiwan;United States
      2020   Phase 1;Phase 3   EUCTR2019-001931-30-AT   Australia;Austria;Netherlands;Taiwan;United States
      2019   Phase 3   JPRN-jRCT2080224823   Africa;Europe;Japan;North America;Oceania
      2019   Phase 3   EUCTR2017-003170-13-NO   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-GR   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-GB   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-003170-13-NL   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-003170-13-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2016   Phase 2   EUCTR2016-000411-32-NL   Canada;Netherlands;United States
      -   Phase 3   EUCTR2017-003170-13-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
   Regeneron Pharmaceuticals, Inc.(ICCC: PAREXEL International)
      2018   -   JPRN-jRCT2080224038   Africa;Europe;Japan;North America;Oceania
Evolocumab
   AMGEN INC.
      2016   Phase 3   EUCTR2015-002276-25-IT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
   Amgen
      2018   Phase 4   NCT03403374   India
      2016   Phase 3   NCT02624869   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czechia;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom;United States
      2016   Phase 3   NCT02392559   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Finland;Greece;Hungary;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2013   Phase 3   NCT01763918   Australia;Canada;France;Germany;Hong Kong;Netherlands;New Zealand;Norway;South Africa;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 2/Phase 3   NCT01624142   Australia;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Netherlands;New Zealand;South Africa;Spain;United Kingdom;United States
      2012   Phase 2/Phase 3   NCT01588496   Belgium;Canada;Czech Republic;Czechia;France;Hong Kong;Italy;Lebanon;Netherlands;New Zealand;South Africa;Spain;United States
      2011   Phase 2   NCT01375751   Canada;Germany;Hong Kong;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
   Amgen Europe B.V.
      2019   Phase 3   EUCTR2015-002276-25-SI   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Swaziland;Switzerland;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Amgen Inc
      2019   Phase 3   EUCTR2015-002276-25-PT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2019   Phase 3   EUCTR2015-002276-25-PL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2014-002277-11-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2014-002277-11-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2014-002277-11-SI   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-002276-25-NL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2017   Phase 3   EUCTR2015-002276-25-ES   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-HU   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-GR   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-DE   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-CZ   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-BE   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-AT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2016   Phase 3   EUCTR2014-002277-11-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-002277-11-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   -   EUCTR2014-002277-11-HU   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Finland;Hungary;Italy;New Zealand;South Africa;Spain;Turkey;United States
      2016   Phase 3   EUCTR2014-002277-11-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2016   -   EUCTR2014-002277-11-FI   Australia;Belgium;Brazil;Canada;Czech Republic;Finland;New Zealand;South Africa;Spain;Turkey;United States
      2016   Phase 3   EUCTR2014-002277-11-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;South Africa;Spain;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-002277-11-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-002277-11-NO   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2015   -   EUCTR2014-002277-11-ES   Australia;Brazil;Canada;New Zealand;South Africa;Spain;Turkey;United States
      2015   Phase 3   EUCTR2014-002277-11-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Netherlands;New Zealand;South Africa;Spain;United Kingdom;United States
      2012   Phase 2   EUCTR2011-001915-29-DE   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Japan;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-SE   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-NO   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-NL   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-HU   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-GB   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-FI   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-DK   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-CZ   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Japan;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-BE   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      -   Phase 3   EUCTR2015-002276-25-NO   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2015-002276-25-GB   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;United Kingdom
      -   -   EUCTR2014-002277-11-Outside-EU/EEA   Australia;Brazil;Canada;New Zealand;South Africa;Turkey;United States
      -   Phase 3   EUCTR2014-002277-11-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom;United States
      -   -   EUCTR2011-005399-40-Outside-EU/EEA   Brazil;Canada;Hong Kong;Lebanon;Malaysia;New Zealand;South Africa;Turkey;United States
   Columbia University
      2018   Phase 4   NCT03331666   United States
   Federico II University
      2017   -   NCT04313270   Italy
   Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
      2019   Phase 4   NCT06231459   Mexico
   Kanazawa University Hospital
      2016   -   JPRN-UMIN000022604   Japan
      2016   -   JPRN-UMIN000022603   Japan
   LIB Therapeutics LLC
      2019   Phase 3   NCT04034485   India;Israel;Norway;South Africa;Turkey;United States
   LIB Therapeutics, LLC
      2020   Phase 3   EUCTR2019-003611-62-NO   Israel;Norway;South Africa;Turkey;United States
   Novartis Pharmaceuticals
      2017   Phase 2   NCT03060577   Canada;Germany;Netherlands;United Kingdom;United States
Extended release niacin / laropiprant
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
      2012   -   EUCTR2012-001443-49-GB   New Zealand;Norway;South Africa;United Kingdom
EZ 10 MG/atorva 10 MG FDC
   Organon and Co
      2015   Phase 3   NCT02460159   Japan
EZ 10 MG/atorva 20 MG FDC
   Organon and Co
      2015   Phase 3   NCT02460159   Japan
EZE
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-GB   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-ES   Australia;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002333-11-DE   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
Ezetimibe
   Akeso
      2019   Phase 2   NCT03933293   China
   Organon and Co
      2016   Phase 3   NCT02748057   Japan
      2007   -   NCT00705211   -
      2007   -   NCT00704444   -
      2006   -   NCT00704535   Philippines
      2002   Phase 3   NCT00552097   -
      2002   Phase 3   NCT00092833   United States
      2000   Phase 3   NCT03885921   -
      2000   Phase 3   NCT03884452   -
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-GB   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-ES   Australia;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002333-11-DE   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
   SCHERING-PLOUGH
      2005   -   EUCTR2004-002627-40-IT   Finland;Germany;Italy;Spain
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
   Schering-Plough Research Institute
      2009   Phase 3   EUCTR2008-006271-70-FR   France;Italy;Netherlands
      2005   Phase 3   EUCTR2004-002627-40-FI   Austria;Finland;Germany;Italy;Spain
      2005   Phase 3   EUCTR2004-002627-40-ES   Austria;Finland;Germany;Italy;Spain
      2005   -   EUCTR2004-002627-40-AT   Austria;Finland;Germany;Italy;Spain
   Schering-Plough Research Institute on behalf of MSP Singapore Company, LLC
      2005   -   EUCTR2004-002627-40-DE   Austria;Finland;Germany;Italy;Spain
Ezetimibe with simvastatin
   Organon and Co
      2005   Phase 3   NCT00129402   Argentina;Austria;Brazil;Canada;Chile;Colombia;Finland;France;Germany;Italy;Mexico;Netherlands;Norway;South Africa;Spain;United States
Ezetrol
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-GB   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-ES   Australia;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002333-11-DE   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
   SCHERING-PLOUGH
      2005   -   EUCTR2004-002627-40-IT   Finland;Germany;Italy;Spain
   Schering-Plough Research Institute
      2009   Phase 3   EUCTR2008-006271-70-FR   France;Italy;Netherlands
      2005   Phase 3   EUCTR2004-002627-40-FI   Austria;Finland;Germany;Italy;Spain
      2005   Phase 3   EUCTR2004-002627-40-ES   Austria;Finland;Germany;Italy;Spain
      2005   -   EUCTR2004-002627-40-AT   Austria;Finland;Germany;Italy;Spain
   Schering-Plough Research Institute on behalf of MSP Singapore Company, LLC
      2005   -   EUCTR2004-002627-40-DE   Austria;Finland;Germany;Italy;Spain
Fenofibrate
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
Fish OIL capsule
   The University of Western Australia
      2012   -   NCT01577056   Australia
Fluvastatin
   Novartis
      2001   Phase 3   NCT00171236   Switzerland
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
Gemcabene
   NeuroBo Pharmaceuticals Inc.
      2016   Phase 2   NCT02722408   Canada;Israel;United States
Gene analysis
   Central South University
      2001   -   NCT01878604   China
Genetic
   Assiut University
      2020   -   NCT03900169   Egypt
   Central South University
      2001   -   NCT01878604   China
   First Affiliated Hospital Xi'an Jiaotong University
      2023   Early Phase 1   NCT06125847   China
   Geisinger Clinic
      2020   Early Phase 1   NCT03832985   United States
   Imperial College London Diabetes Centre
      2017   -   NCT03597958   United Arab Emirates
   Nantes University Hospital
      2017   -   NCT03234127   France
Genetic testing
   Children's Hospital,Zhejiang University School of Medicine
      2025   -   ChiCTR2500115103   China
   National Medical Research Center for Therapy and Preventive Medicine
      2020   -   NCT04656028   Russian Federation
   Tada Hayato
      2025   -   JPRN-jRCT1040250123   -
GZ402661
   Genzyme Corporation and its Affiliates
      2013   -   EUCTR2011-001480-42-DK   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-PL   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-HU   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-GB   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-DE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-CZ   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-BE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
Heparin
   Osaka University Graduate School of Medicine
      2016   Phase 1   JPRN-UMIN000020591   Japan
Heparin-induced extracorporeal LDL precipitation
   Laval University
      2013   -   NCT02286596   Canada
Historical data OF lipid-lowering drug administration
   Central South University
      2001   -   NCT01878604   China
Historical data OF plasma lipids, xanthoma changes
   Central South University
      2001   -   NCT01878604   China
HMG coenzyme reductase
   The University of Western Australia
      2012   -   NCT01577056   Australia
IBI306
   Innovent Biologics (Suzhou) Co. Ltd.
      2026   Phase 3   NCT07473960   China
      2019   Phase 3   NCT04179669   China
      2019   Phase 2/Phase 3   NCT04031742   China
   Shenzhen People's Hospital
      2019   Phase 2/Phase 3   NCT04948008   China
IBI306 450MG SC Q4W
   Innovent Biologics (Suzhou) Co. Ltd.
      2020   Phase 3   NCT04289285   China
IBI306 600MG SC Q6W
   Innovent Biologics (Suzhou) Co. Ltd.
      2020   Phase 3   NCT04289285   China
Implitapide
   Medical Research Laboratories International
      2003   Phase 2   NCT00079859   Netherlands;Norway;United States
      2003   Phase 2   NCT00079846   Canada;Israel;Netherlands;Norway;United States
Inclisiran
   Novartis Pharmaceuticals
      2025   -   NCT06958315   Spain
      2025   Phase 3   NCT06597006   Austria;China;Germany;Greece;Malaysia;Netherlands;South Africa;Taiwan;Turkey (Türkiye);United Kingdom;United States
      2024   Phase 3   NCT06597019   Argentina;Austria;Belgium;Brazil;China;Czechia;France;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Portugal;South Africa;Spain;Taiwan;Turkey (Türkiye);United Kingdom;United States
      2024   -   NCT06275724   Japan
      2023   Phase 3   NCT05682378   Argentina;Brazil;Canada;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russia;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey (Türkiye);United Kingdom;United States
      2021   Phase 3   NCT04659863   Canada;France;Greece;Lebanon;Malaysia;Netherlands;Slovenia;Switzerland;Turkey (Türkiye);United States;Vietnam
      2021   Phase 3   NCT04652726   Argentina;Australia;Brazil;Canada;Croatia;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russia;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey (Türkiye);United Kingdom;United States;Vietnam
      2017   Phase 2   NCT03060577   Canada;Germany;Netherlands;United Kingdom;United States
   The Medicines Company
      2017   Phase 3   NCT03397121   Canada;Czechia;Denmark;Israel;Netherlands;South Africa;Spain;Sweden;United Kingdom;United States
Inclisiran (leqvio®) 300MG
   CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
      2024   Phase 2   NCT07421232   China
Inclisiran FOR injection
   The Medicines Company
      2018   Phase 3   EUCTR2017-002472-30-GB   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-SE   Canada;Czech Republic;Denmark;Israel;Netherlands;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-ES   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-DK   Canada;Czech Republic;Denmark;Netherlands;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-CZ   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;South Africa;Spain;Sweden;United Kingdom;United States
Inclisiran sodium
   NOVARTIS PHARMA AG
      2023   Phase 3   EUCTR2022-002316-23-IT   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-002757-18-IT   Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Netherlands;Norway;Poland;Russian Federation;Serbia;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Novartis Pharma AG
      2023   Phase 3   EUCTR2022-002316-23-SI   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-PL   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-NL   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-DE   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2022-002316-23-NO   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2022-002316-23-HU   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2020-002757-18-SK   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002757-18-SI   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
      2021   Phase 3   EUCTR2020-002757-18-PL   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002757-18-NL   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United States
      2021   Phase 3   EUCTR2020-002757-18-HR   Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Netherlands;Norway;Poland;Russian Federation;Serbia;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2021   Phase 3   EUCTR2020-002757-18-GR   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
      2021   Phase 3   EUCTR2020-002757-18-FR   Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Netherlands;Norway;Poland;Russian Federation;Serbia;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2021   Phase 3   EUCTR2020-002757-18-DE   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002755-38-NL   Canada;France;Greece;Lebanon;Malaysia;Netherlands;Slovenia;Turkey;United States
      2021   Phase 3   EUCTR2020-002755-38-GR   Canada;France;Greece;Lebanon;Malaysia;Netherlands;Slovenia;Turkey;United States
      2021   Phase 3   EUCTR2020-002755-38-FR   Canada;France;Greece;Lebanon;Netherlands;Serbia;Slovenia;Switzerland;Türkiye;United States
      2020   Phase 3   EUCTR2020-002757-18-NO   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United States
      2020   Phase 3   EUCTR2020-002757-18-HU   Australia;Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Serbia;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2020   Phase 3   EUCTR2020-002755-38-SI   Canada;France;Germany;Greece;Italy;Lebanon;Netherlands;Serbia;Slovenia;South Africa;Switzerland;Türkiye;United States;Viet Nam
      -   Phase 3   EUCTR2022-002316-23-GR   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2022-002316-23-FR   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2020-002757-18-CZ   Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Serbia;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
   Novartis Pharmaceuticals
      2021   Phase 2   NCT04666298   Japan
      2019   Phase 3   NCT03814187   Canada;Czechia;Denmark;Germany;Hungary;Netherlands;Poland;South Africa;Spain;Sweden;Ukraine;United Kingdom;United States
   The Medicines Company
      2018   Phase 3   EUCTR2017-002472-30-GB   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-SE   Canada;Czech Republic;Denmark;Israel;Netherlands;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-ES   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-DK   Canada;Czech Republic;Denmark;Netherlands;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002472-30-CZ   Austria;Canada;Czech Republic;Denmark;France;Israel;Netherlands;Norway;South Africa;Spain;Sweden;United Kingdom;United States
   Yamada Hiroyuki
      2021   Phase 2   JPRN-jRCT2031200313   -
Inclisiran sodium FOR injection
   Novartis Pharmaceuticals
      2019   Phase 3   NCT03851705   Czechia;Hong Kong;Israel;Russian Federation;Serbia;South Africa;Taiwan;Turkey;Ukraine
Ionis angptl3-LRX
   Ionis Pharmaceuticals, Inc.
      2015   Phase 1   NCT02709850   Canada
Isis 301012
   GENZYME EUROPE BV
      2012   -   EUCTR2011-001480-42-IT   Argentina;Australia;Belgium;Brazil;Canada;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Genzyme Corporation and its Affiliates
      2013   -   EUCTR2011-001480-42-DK   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-SK   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-SE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-PL   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-NL   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-HU   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-GR   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-GB   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-FR   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;France;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-ES   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-DE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-CZ   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-BE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Kastle Therapeutics, LLC
      2006   Phase 2   NCT00281008   Netherlands;United States
      2006   Phase 2   NCT00280995   Netherlands;United States
Isis 301012 phosphorothioate oligonucleotide
   Genzyme Europe B.V.
      2008   Phase 3   EUCTR2005-003450-10-GB   United Kingdom
      2007   Phase 3   EUCTR2005-003449-15-GB   United Kingdom
Isis 703802
   Ionis Pharmaceuticals, Inc.
      2016   Phase 1;Phase 2   EUCTR2015-004003-23-IT   Canada;Italy;Netherlands
JS002
   Shanghai Junshi Bioscience Co., Ltd.
      2020   Phase 2   NCT04515927   China
KB2115
   Karo Bio AB
      2011   -   EUCTR2011-001483-21-SE   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-GB   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-ES   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   Phase 3   EUCTR2011-001483-21-DK   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-CZ   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
      2011   -   EUCTR2011-001483-21-AT   Austria;Czech Republic;Denmark;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom
KJX839
   NOVARTIS PHARMA AG
      2023   Phase 3   EUCTR2022-002316-23-IT   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-002757-18-IT   Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Netherlands;Norway;Poland;Russian Federation;Serbia;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Novartis Pharma AG
      2023   Phase 3   EUCTR2022-002316-23-SI   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-PL   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-NL   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-DE   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2022-002316-23-NO   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2022-002316-23-HU   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2020-002757-18-SK   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002757-18-SI   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
      2021   Phase 3   EUCTR2020-002757-18-PL   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002757-18-NL   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United States
      2021   Phase 3   EUCTR2020-002757-18-HR   Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Netherlands;Norway;Poland;Russian Federation;Serbia;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2021   Phase 3   EUCTR2020-002757-18-GR   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
      2021   Phase 3   EUCTR2020-002757-18-FR   Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Netherlands;Norway;Poland;Russian Federation;Serbia;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2021   Phase 3   EUCTR2020-002757-18-DE   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002755-38-NL   Canada;France;Greece;Lebanon;Malaysia;Netherlands;Slovenia;Turkey;United States
      2021   Phase 3   EUCTR2020-002755-38-GR   Canada;France;Greece;Lebanon;Malaysia;Netherlands;Slovenia;Turkey;United States
      2021   Phase 3   EUCTR2020-002755-38-FR   Canada;France;Greece;Lebanon;Netherlands;Serbia;Slovenia;Switzerland;Türkiye;United States
      2020   Phase 3   EUCTR2020-002757-18-NO   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United States
      2020   Phase 3   EUCTR2020-002757-18-HU   Australia;Brazil;Canada;Croatia;Czech Republic;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Serbia;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2020   Phase 3   EUCTR2020-002755-38-SI   Canada;France;Germany;Greece;Italy;Lebanon;Netherlands;Serbia;Slovenia;South Africa;Switzerland;Türkiye;United States;Viet Nam
      -   Phase 3   EUCTR2022-002316-23-GR   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2022-002316-23-FR   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2020-002757-18-CZ   Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Serbia;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
Krill OIL
   Hospital do Coracao
      2024   -   NCT06331195   Brazil
      2023   -   NCT05695937   Brazil
Kynamro
   Genzyme Corporation and its Affiliates
      2013   -   EUCTR2011-001480-42-DK   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-PL   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-HU   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-GB   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-DE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-CZ   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-BE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
Lactobacillus paracasei B21060
   Federico II University
      2012   Phase 1/Phase 2   NCT02048410   -
Lapaquistat acetate and current lipid-lowering treatment
   Takeda
      2005   Phase 3   NCT00263081   Canada;France;Israel;Poland;United Kingdom;United States
Laropiprant
   Merck Sharp & Dohme Corp.
      2006   Phase 3   NCT00384293   Australia;Belgium;Canada;France;Germany;Israel;Netherlands;New Zealand;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Leqvio
   Semmelweis University
      2023   Phase 4   EUCTR2023-000166-33-HU   Hungary
Leqvio 284 MG solution FOR injection IN PRE-filled syringe
   NOVARTIS PHARMA AG
      2023   Phase 3   EUCTR2022-002316-23-IT   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;United Kingdom;United States
   Novartis Pharma AG
      2023   Phase 3   EUCTR2022-002316-23-SI   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-PL   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-NL   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2022-002316-23-DE   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2022-002316-23-NO   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2022-002316-23-HU   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2020-002757-18-SK   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002757-18-SI   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
      2021   Phase 3   EUCTR2020-002757-18-PL   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002757-18-NL   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United States
      2021   Phase 3   EUCTR2020-002757-18-GR   Argentina;Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
      2021   Phase 3   EUCTR2020-002757-18-DE   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Türkiye;United States
      2021   Phase 3   EUCTR2020-002755-38-NL   Canada;France;Greece;Lebanon;Malaysia;Netherlands;Slovenia;Turkey;United States
      2021   Phase 3   EUCTR2020-002755-38-GR   Canada;France;Greece;Lebanon;Malaysia;Netherlands;Slovenia;Turkey;United States
      2020   Phase 3   EUCTR2020-002757-18-NO   Argentina;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United States
      2020   Phase 3   EUCTR2020-002755-38-SI   Canada;France;Germany;Greece;Italy;Lebanon;Netherlands;Serbia;Slovenia;South Africa;Switzerland;Türkiye;United States;Viet Nam
      -   Phase 3   EUCTR2022-002316-23-GR   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2022-002316-23-FR   Brazil;Canada;France;Germany;Greece;Hungary;Israel;Italy;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2020-002757-18-CZ   Australia;Brazil;Canada;Croatia;Czech Republic;Czechia;France;Germany;Greece;Hungary;Israel;Italy;Jordan;Lebanon;Malaysia;Netherlands;Norway;Poland;Russian Federation;Serbia;Singapore;Slovakia;Slovenia;South Africa;Spain;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States;Viet Nam
Lerodalcibep
   Hasten Biopharmaceutical Co., Ltd.
      2024   Phase 3   NCT06568471   China
   LIB Therapeutics LLC
      2021   Phase 3   NCT04797104   Israel;Norway;South Africa;Turkey;United States
      2020   Phase 3   NCT04798430   India;Israel;Norway;South Africa;Turkey;United States
      2019   Phase 3   NCT04034485   India;Israel;Norway;South Africa;Turkey;United States
   LIB Therapeutics, LLC
      2022   Phase 3   EUCTR2020-004394-49-FR   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2020-004394-49-ES   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2020-004394-49-DE   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Türkiye;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004394-49-NO   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004390-44-NO   Canada;France;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United States
      2021   Phase 3   EUCTR2020-004390-44-ES   Canada;France;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United States
Lerodalcibep 300 MG monthly SC
   LIB Therapeutics LLC
      2025   Phase 3   NCT07102511   South Africa;Turkey (Türkiye);United States
LIB003
   LIB Therapeutics, LLC
      2022   Phase 3   EUCTR2020-004394-49-FR   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2020-004394-49-ES   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 3   EUCTR2020-004394-49-DE   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Türkiye;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004394-49-NO   Canada;France;Germany;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004390-44-NO   Canada;France;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United States
      2021   Phase 3   EUCTR2020-004390-44-ES   Canada;France;India;Israel;New Zealand;Norway;South Africa;Spain;Turkey;United States
      2020   Phase 3   EUCTR2019-003611-62-NO   Israel;Norway;South Africa;Turkey;United States
Lipid analysis
   National Medical Research Center for Therapy and Preventive Medicine
      2020   -   NCT04656028   Russian Federation
Lipid-lowering treatments
   Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
      2015   -   NCT06362473   Italy
Lipitor
      2005   -   EUCTR2004-004269-14-DK   Denmark;Iceland;Sweden
   Pfizer
      2005   Phase 3   EUCTR2004-004269-14-IS   Denmark;Iceland;Sweden
   Pfizer AB
      2005   -   EUCTR2004-004269-14-SE   Denmark;Iceland;Sweden
   Pfizer Inc
      2009   Phase 3   EUCTR2008-006130-95-BE   Belgium;Germany;Greece;Hungary;Italy;Slovakia;Spain
Livazo 1 MG FILM-coated tablets
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004964-32-NL   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-GR   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
      -   -   EUCTR2011-004964-32-NO   Greece;Italy;Netherlands;Norway;Spain
Livazo 1MG FILM-coated tablets
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004983-32-NO   Greece;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-NL   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-GR   Greece;Italy;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
Livazo 2 MG FILM-coated tablets
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004964-32-NL   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-GR   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
      -   -   EUCTR2011-004964-32-NO   Greece;Italy;Netherlands;Norway;Spain
Livazo 2MG FILM-coated tablets
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004983-32-NO   Greece;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-NL   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-GR   Greece;Italy;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
Livazo 4 MG FILM-coated tablets
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004964-32-NL   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-GR   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
      -   -   EUCTR2011-004964-32-NO   Greece;Italy;Netherlands;Norway;Spain
Livazo 4MG FILM-coated tablets
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004983-32-NO   Greece;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-NL   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-GR   Greece;Italy;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
Lojuxta 10 MG hard capsules
   Amryt Pharmaceuticals DAC
      2020   Phase 3   EUCTR2019-002278-30-IT   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia;Turkey
      2020   Phase 3   EUCTR2019-002278-30-DE   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia
Lojuxta 20 MG hard capsules
   Amryt Pharmaceuticals DAC
      2020   Phase 3   EUCTR2019-002278-30-IT   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia;Turkey
      2020   Phase 3   EUCTR2019-002278-30-DE   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia
Lojuxta 5 MG hard capsules
   Amryt Pharmaceuticals DAC
      2020   Phase 3   EUCTR2019-002278-30-IT   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia;Turkey
      2020   Phase 3   EUCTR2019-002278-30-DE   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia
Lomitapide
   AEGERION PHARMACEUTICALS
      2011   -   EUCTR2010-023742-79-IT   Italy
   Aegerion Pharmaceuticals Inc.
      2016   Phase 3   EUCTR2014-003806-33-GR   Austria;Canada;Germany;Greece;Israel;Italy;Turkey
   Aegerion Pharmaceuticals, Inc.
      2016   Phase 3   NCT02765841   -
      2015   -   NCT02399852   -
      2014   Phase 3   NCT02173158   Japan
      2009   Phase 3   NCT00943306   Canada;Italy;South Africa;United States
      2003   Phase 2   NCT01556906   United States
   Amryt Pharma
      2020   Phase 3   NCT04681170   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia
      2014   -   NCT02135705   Argentina;Canada;France;Greece;Italy;Netherlands;United Kingdom;United States
Lomitapide 2MG hard capsules
   Amryt Pharmaceuticals DAC
      2020   Phase 3   EUCTR2019-002278-30-IT   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia;Turkey
      2020   Phase 3   EUCTR2019-002278-30-DE   Germany;Israel;Italy;Saudi Arabia;Spain;Tunisia
Lovastatin
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
LOW satured diet
   Federico II University
      2012   Phase 1/Phase 2   NCT02048410   -
Maintenance OF specific diet
   AstraZeneca
      2002   Phase 3   NCT00654602   -
MBX-8025
   CymaBay Therapeutics, Inc.
      2015   Phase 2   NCT02472535   Canada;France;Netherlands;Norway
      2015   Phase 2   EUCTR2014-004856-68-NO   France;Netherlands;Norway
      2015   -   EUCTR2014-004856-68-NL   France;Netherlands;Norway
      2015   Phase 2   EUCTR2014-004856-68-FR   France;Netherlands;Norway
MGL-3196
   Madrigal Pharmaceuticals, Inc.
      2017   Phase 2   NCT03038022   Denmark;Netherlands;Norway
      2017   Phase 2   EUCTR2016-002315-17-NO   Denmark;Netherlands;Norway
      2017   Phase 2   EUCTR2016-002315-17-NL   Denmark;Netherlands;Norway
      2017   Phase 2   EUCTR2016-002315-17-DK   Denmark;Netherlands;Norway
Mipomersen
   GENZYME EUROPE BV
      2012   -   EUCTR2011-001480-42-IT   Argentina;Australia;Belgium;Brazil;Canada;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Genzyme Corporation and its Affiliates
      2013   -   EUCTR2011-001480-42-DK   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-SK   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-SE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-PL   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-NL   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-HU   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-GR   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-GB   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-FR   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;France;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-ES   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   Phase 3   EUCTR2011-001480-42-DE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-CZ   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2012   -   EUCTR2011-001480-42-BE   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;Slovakia;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Kastle Therapeutics, LLC
      2007   Phase 3   NCT00607373   Brazil;Canada;Netherlands;Singapore;South Africa;Taiwan;United Kingdom;United States
Mipomersen sodium
   Genzyme Europe B.V.
      2008   Phase 3   EUCTR2005-003450-10-GB   United Kingdom
   Kastle Therapeutics, LLC
      2008   Phase 3   NCT00706849   Canada;United States
      2008   Phase 3   NCT00694109   Brazil;Canada;Singapore;South Africa;Taiwan;United Kingdom;United States
      2007   Phase 2   NCT00477594   Netherlands;United States
Mipomersen sodium 200 MG
   Kastle Therapeutics, LLC
      2011   Phase 3   NCT01475825   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Czechia;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
Mipomersen sodium 70 MG
   Kastle Therapeutics, LLC
      2011   Phase 3   NCT01475825   Argentina;Australia;Belgium;Brazil;Canada;Croatia;Czech Republic;Czechia;Denmark;Germany;Greece;Hong Kong;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;New Zealand;Norway;Poland;Russian Federation;South Africa;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
MK-0524 or L-000888839-000E
   Laboratoires Merck Sharp & Dohme - Chibret
      2007   Phase 3   EUCTR2006-001913-13-FR   France;Germany;Sweden;United Kingdom
   Merck & Co., Inc
      2007   -   EUCTR2006-001913-13-SE   France;Germany;Sweden;United Kingdom
   Merck & Co., Inc.
      2006   Phase 3   EUCTR2006-001913-13-DE   France;Germany;Sweden;United Kingdom
   Merck Sharp & Dohme Limited
      2007   Phase 3   EUCTR2006-001913-13-GB   France;Germany;Sweden;United Kingdom
MK-0524A
   Merck Sharp & Dohme Corp.
      2012   Phase 1   NCT01583647   New Zealand;Norway;South Africa
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
      2012   -   EUCTR2012-001443-49-GB   New Zealand;Norway;South Africa;United Kingdom
MK-0524A (ER-niacin/MK-0524) 1G/20MG or MK-0524A
   Laboratoires Merck Sharp & Dohme - Chibret
      2007   Phase 3   EUCTR2006-001913-13-FR   France;Germany;Sweden;United Kingdom
   Merck & Co., Inc
      2007   -   EUCTR2006-001913-13-SE   France;Germany;Sweden;United Kingdom
   Merck & Co., Inc.
      2006   Phase 3   EUCTR2006-001913-13-DE   France;Germany;Sweden;United Kingdom
   Merck Sharp & Dohme Limited
      2007   Phase 3   EUCTR2006-001913-13-GB   France;Germany;Sweden;United Kingdom
MK-0524A (ER-niacin/MK-0524) 1G/20MG tablets or MK-0524A
   Merck & Co., Inc
      2007   -   EUCTR2006-001913-13-SE   France;Germany;Sweden;United Kingdom
   Merck & Co., Inc.
      2006   Phase 3   EUCTR2006-001913-13-DE   France;Germany;Sweden;United Kingdom
   Merck Sharp & Dohme Limited
      2007   Phase 3   EUCTR2006-001913-13-GB   France;Germany;Sweden;United Kingdom
MK-0616
   Merck Sharp & Dohme LLC
      2022   Phase 2   NCT05261126   Germany;Japan;Korea, Republic of;Mexico;Norway;Turkey;United Kingdom;United States
MK-0859
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
      2013   Phase 3   EUCTR2012-002434-37-IT   Brazil;Canada;Czech Republic;Israel;Italy;Malaysia;Norway;South Africa;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002434-37-GB   Australia;Canada;Czech Republic;Israel;Italy;Malaysia;Norway;South Africa;United Kingdom;United States
      2013   -   EUCTR2012-002434-37-CZ   Australia;Canada;Czech Republic;Israel;Malaysia;Norway;South Africa;United Kingdom;United States
      2012   -   EUCTR2012-002434-37-NO   Australia;Canada;Czech Republic;Israel;Malaysia;Norway;South Africa;United Kingdom;United States
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
      2012   Phase 3   EUCTR2011-004525-27-NL   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   Phase 3   EUCTR2011-004525-27-GB   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   Phase 3   EUCTR2011-004525-27-ES   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   Phase 3   EUCTR2011-004525-27-DE   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
      2012   -   EUCTR2011-004525-27-CZ   Canada;Czech Republic;France;Germany;Netherlands;Norway;Russian Federation;Spain;United Kingdom;United States
Monotherapy ezetimibe
   NewAmsterdam Pharma
      2024   Phase 3   NCT06005597   United States
Monotherapy obicetrapib
   NewAmsterdam Pharma
      2024   Phase 3   NCT06005597   United States
Motivational counseling
   National Medical Research Center for Therapy and Preventive Medicine
      2020   -   NCT04656028   Russian Federation
NGGT006
   First Affiliated Hospital Xi'an Jiaotong University
      2023   Early Phase 1   NCT06125847   China
   Suzhou Municipal Hospital
      2024   Early Phase 1   NCT06293729   -
Niacin
   Merck Sharp & Dohme Corp.
      2006   Phase 3   NCT00384293   Australia;Belgium;Canada;France;Germany;Israel;Netherlands;New Zealand;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Nicotinic acid
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
Nicotinic acid/laropiprant
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
      2012   -   EUCTR2012-001443-49-GB   New Zealand;Norway;South Africa;United Kingdom
Nilemdo
   Esperion Therapeutics, Inc.
      2023   Phase 2   EUCTR2018-004084-31-NL   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2018-004084-31-ES   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2018-004084-31-DE   Canada;Denmark;Germany;Netherlands;Spain;United Kingdom;United States
NK 104
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004983-32-NO   Greece;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-NL   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-GR   Greece;Italy;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-NL   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-GR   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
      -   -   EUCTR2011-004964-32-NO   Greece;Italy;Netherlands;Norway;Spain
Normal saline
   Arrowhead Pharmaceuticals
      2019   Phase 1   NCT03747224   Australia;New Zealand
   The Medicines Company
      2016   Phase 2   NCT02597127   Canada;Germany;Netherlands;United Kingdom;United States
Obicetrapib
   A. Menarini International Licensing S.A.
      2026   Phase 3   NCT07614958   United Kingdom
   NewAmsterdam Pharma
      2022   Phase 3   NCT05425745   Canada;Czechia;Georgia;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2021   Phase 3   NCT05142722   China;Czechia;Denmark;Georgia;Japan;Netherlands;Poland;United States
   NewAmsterdam Pharma B.V.
      2023   Phase 3   EUCTR2021-005064-22-PL   Canada;Czech Republic;Czechia;Georgia;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005065-40-NL   China;Czech Republic;Czechia;Denmark;Georgia;Japan;Netherlands;Poland;United States
      2022   Phase 3   EUCTR2021-005065-40-DK   China;Czech Republic;Czechia;Denmark;Georgia;Japan;Netherlands;Poland;United States
      2022   Phase 3   EUCTR2021-005065-40-CZ   China;Czech Republic;Czechia;Denmark;Georgia;Japan;Netherlands;Poland;United States
      2022   Phase 3   EUCTR2021-005064-22-NL   Canada;Czech Republic;Czechia;Georgia;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005064-22-CZ   Canada;Czech Republic;Czechia;Georgia;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
Omega-3
   Nordlandssykehuset HF
      2013   Phase 3   NCT01813006   Norway
Omega-3 fatty acids
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
Ongericimab
   Shanghai Junshi Bioscience Co., Ltd.
      2021   Phase 3   NCT05325203   China
Pactimibe sulfate
   Daiichi Sankyo Inc.
      2004   Phase 2/Phase 3   NCT00151788   Canada;Israel;Netherlands;Norway;South Africa;Spain;Sweden;United Kingdom;United States
PF-04950615
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2014   Phase 3   EUCTR2013-002644-87-GB   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002644-87-ES   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002644-87-BG   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-NO   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-NL   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-IT   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-FI   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
Phytosterol
   Hospital do Coracao
      2024   -   NCT06331195   Brazil
      2023   -   NCT05695937   Brazil
Pitavastatin calcium
   Kowa Research Europe, Ltd.
      2012   -   EUCTR2011-004983-32-NO   Greece;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-NL   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-GR   Greece;Italy;Netherlands;Norway
      2012   -   EUCTR2011-004983-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004983-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-NL   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-GR   Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-FR   France;Greece;Italy;Netherlands;Norway;Spain
      2012   -   EUCTR2011-004964-32-ES   France;Greece;Italy;Netherlands;Norway;Spain
      -   -   EUCTR2011-004964-32-NO   Greece;Italy;Netherlands;Norway;Spain
Praluent
   Fundación Hipercolesterolemia Familiar
      2018   Phase 4   EUCTR2017-004299-69-ES   Spain
   REGENERON PHARMACEUTICALS, INC.
      2019   Phase 3   EUCTR2017-003170-13-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-001388-19-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      2017   Phase 3   EUCTR2017-000351-95-IT   Austria;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals
      2018   Phase 4   NCT03694197   Bulgaria;Estonia;Russian Federation;South Africa;Ukraine;United States
      2016   Phase 4   NCT02957682   Bulgaria;Chile;Colombia;Estonia;Japan;Mexico;Russian Federation;South Africa;Ukraine;United States
   Regeneron Pharmaceuticals Inc.
      2018   Phase 3   EUCTR2017-001388-19-GR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-DE   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      -   Phase 3   EUCTR2017-001388-19-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      -   Phase 3   EUCTR2017-001388-19-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals, Inc.
      2019   Phase 4   EUCTR2018-002810-11-BG   Bulgaria;Chile;Estonia;Mexico;Russian Federation;South Africa;Ukraine;United States
      2019   Phase 3   EUCTR2017-003170-13-GR   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 4   EUCTR2018-002810-11-EE   Bulgaria;Chile;Estonia;Mexico;Russian Federation;South Africa;Ukraine;United States
      2018   Phase 3   EUCTR2017-003170-13-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2017-000351-95-GR   Austria;Canada;Czech Republic;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
      2017   Phase 3   EUCTR2017-000351-95-FR   Austria;Belgium;Bulgaria;Canada;Croatia;Czech Republic;Denmark;France;Germany;Greece;Israel;Italy;Netherlands;Poland;Portugal;Serbia;Slovenia;South Africa;Spain;Sweden;Tunisia;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2017-000351-95-DE   Austria;Canada;Czech Republic;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
      2017   Phase 3   EUCTR2017-000351-95-AT   Austria;Canada;Czech Republic;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
      2017   Phase 4   EUCTR2016-003189-16-SK   Argentina;Bulgaria;Chile;Colombia;Estonia;Israel;Japan;Mexico;Peru;Russian Federation;Slovakia;South Africa;Ukraine;United States
      2017   Phase 4   EUCTR2016-003189-16-BG   Argentina;Bulgaria;Chile;Colombia;Czech Republic;Denmark;Estonia;Germany;Hungary;Israel;Japan;Mexico;Netherlands;Poland;Romania;Russian Federation;Slovakia;South Africa;United Kingdom;United States
      2016   Phase 4   EUCTR2016-003189-16-EE   Argentina;Bulgaria;Chile;Colombia;Estonia;Israel;Japan;Mexico;Peru;Russian Federation;Slovakia;South Africa;Ukraine;United States
      -   Phase 3   EUCTR2017-003170-13-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
      -   Phase 3   EUCTR2017-000351-95-CZ   Austria;Belgium;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Israel;Italy;Netherlands;Poland;Portugal;Serbia;Slovenia;South Africa;Spain;Sweden;Tunisia;Turkey;Ukraine;United Kingdom;United States
   Sanofi-Aventis Recherche & Développement
      2018   Phase 3   EUCTR2017-002297-39-DK   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
   sanofi-aventis recherche et développement
      2014   Phase 3   EUCTR2013-002572-40-PT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-HU   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-GB   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-FI   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DK   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BG   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-AT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-NL   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Pravastatin
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
Prednisone
   REGENXBIO Inc.
      2017   Phase 1;Phase 2   EUCTR2016-001446-25-IT   Canada;Italy;Netherlands;United States
Prevenar13
   Maastricht University
      2016   Phase 4   EUCTR2015-004846-25-BE   Belgium
Probucol
   Cardiology, Osaka University Graduate School of Medicine
      2016   -   JPRN-UMIN000024187   Japan
   Chinese University of Hong Kong
      2013   Phase 1 study   ChiCTR-ONC-13003008   China
Protein convertase subtilisin/kexin type 9 inhibitor
   Shenzhen People's Hospital
      2020   Phase 3   NCT04759534   China
Pufa muffin
   University of Oslo
      2016   -   NCT02729857   Norway
QLC7401
   Qilu Pharmaceutical Co., Ltd.
      2026   Phase 3   NCT07444086   -
QLC7401 injection
   Qilu Pharmaceutical Co., Ltd.
      2026   Phase 3   NCT07450378   -
R727
   REGENERON PHARMACEUTICALS, INC.
      2017   Phase 3   EUCTR2017-000351-95-IT   Austria;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;South Africa;Turkey;Ukraine;United States
Rapeseed OIL
   Medical University of Vienna
      2009   -   NCT00924339   Austria
      2008   -   NCT00924274   Austria
Receive A pediatric-onset result
   Geisinger Clinic
      2020   Early Phase 1   NCT03832985   United States
Receive AN adult-onset result
   Geisinger Clinic
      2020   Early Phase 1   NCT03832985   United States
Recombinant human apolipoprotein
   CERENIS THERAPEUTICS SA
      2012   -   EUCTR2011-003998-28-IT   Canada;Italy;Netherlands;United Kingdom;United States
Recombinant human apolipoprotein A-I/phospholipids complex
   Cerenis Therapeutics
      2012   -   EUCTR2011-003998-28-NL   Canada;France;Italy;Netherlands;United Kingdom;United States
      2012   Phase 2   EUCTR2011-003998-28-GB   Canada;Italy;Netherlands;United Kingdom;United States
Recombinant human apolipoprotein A1
   Cerenis Therapeutics
      2012   Phase 2   EUCTR2011-003998-28-GB   Canada;Italy;Netherlands;United Kingdom;United States
Regn 727
   Regeneron Pharmaceuticals Inc.
      2012   -   EUCTR2012-001222-95-NL   Czech Republic;Netherlands;United Kingdom
      2012   -   EUCTR2012-001222-95-GB   Czech Republic;Netherlands;United Kingdom
      2012   -   EUCTR2012-001222-95-CZ   Czech Republic;Netherlands;United Kingdom
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-ES   Australia;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
REGN1500
   REGENERON PHARMACEUTICALS, INC.
      2019   Phase 3   EUCTR2017-003170-13-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-001388-19-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals Inc.
      2018   Phase 3   EUCTR2017-001388-19-GR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-DE   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      2018   Phase 3   EUCTR2017-001388-19-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      -   Phase 3   EUCTR2017-001388-19-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
      -   Phase 3   EUCTR2017-001388-19-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
   Regeneron Pharmaceuticals, Inc.
      2020   Phase 1;Phase 3   EUCTR2019-001931-30-NL   Australia;Austria;Netherlands;Taiwan;United States
      2020   Phase 1;Phase 3   EUCTR2019-001931-30-AT   Australia;Austria;Netherlands;Taiwan;United States
      2019   Phase 3   EUCTR2017-003170-13-NO   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-GR   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-GB   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2017-003170-13-AT   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-003170-13-NL   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2017-003170-13-CZ   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;South Africa;Ukraine;United Kingdom;United States
      2016   Phase 2   EUCTR2016-000411-32-NL   Canada;Netherlands;United States
      -   Phase 3   EUCTR2017-003170-13-FR   Australia;Austria;Canada;Czech Republic;France;Germany;Greece;Italy;Japan;Netherlands;Norway;South Africa;Turkey;Ukraine;United Kingdom;United States
REGN1500 250 MG SC/15 MG/KG IV/450 MG SC
   Regeneron Pharmaceuticals
      2015   Phase 2   NCT02265952   Canada;Netherlands;United States
REGN727
   REGENERON PHARMACEUTICALS, INC.
      2018   Phase 3   EUCTR2017-001388-19-IT   Australia;Austria;Canada;Czech Republic;Czechia;France;Germany;Greece;Italy;Netherlands;South Africa;Turkey;Ukraine;United States
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
   sanofi-aventis Recherche & Développement
      2012   -   EUCTR2012-001096-37-NL   Canada;India;Netherlands;Russian Federation;South Africa;United States
      2012   -   EUCTR2011-005109-56-SE   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   Phase 3   EUCTR2011-005109-56-NO   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   Phase 3   EUCTR2011-005109-56-NL   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-GB   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-ES   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-DK   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-CZ   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-AT   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
   sanofi-aventis recherche et développement
      2014   Phase 3   EUCTR2013-002572-40-RO   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-PT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-NO   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-HU   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-GB   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-FI   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DK   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-CZ   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BG   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-AT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-NL   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-IT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-ES   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
REGN727/SAR236553
   Regeneron Pharmaceuticals Inc.
      2012   -   EUCTR2012-001222-95-NL   Czech Republic;Netherlands;United Kingdom
      2012   -   EUCTR2012-001222-95-GB   Czech Republic;Netherlands;United Kingdom
      2012   -   EUCTR2012-001222-95-CZ   Czech Republic;Netherlands;United Kingdom
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-GB   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-ES   Australia;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002333-11-DE   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
Repatha 140 MG solution FOR injection IN PRE-filled PEN
   Amgen Europe B.V.
      2019   Phase 3   EUCTR2015-002276-25-SI   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Swaziland;Switzerland;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Amgen Inc
      2019   Phase 3   EUCTR2015-002276-25-PT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2019   Phase 3   EUCTR2015-002276-25-PL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2014-002277-11-SI   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-002276-25-NL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2017   Phase 3   EUCTR2015-002276-25-ES   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Romania;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-HU   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-GR   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-DE   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-CZ   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-BE   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-AT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2013   Phase 2;Phase 3   EUCTR2011-005400-15-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;France;Greece;Hong Kong;Israel;Italy;Japan;Lebanon;Netherlands;New Zealand;South Africa;Spain;United Kingdom;United States
      2012   Phase 2   EUCTR2011-001915-29-DE   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Japan;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      2011   Phase 2   EUCTR2011-001915-29-CZ   Australia;Belgium;Canada;Czech Republic;Denmark;European Union;Finland;Germany;Hong Kong;Hungary;Japan;Netherlands;Norway;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
      -   Phase 3   EUCTR2015-002276-25-NO   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2015-002276-25-GB   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;United Kingdom
Repatha 420 MG solution FOR injection IN cartridge
   Amgen Europe B.V.
      2019   Phase 3   EUCTR2015-002276-25-SI   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Swaziland;Switzerland;Taiwan;Turkey;Ukraine;United Kingdom;United States
   Amgen Inc
      2019   Phase 3   EUCTR2015-002276-25-PT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2019   Phase 3   EUCTR2015-002276-25-PL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Malaysia;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-002276-25-NL   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-CZ   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-BE   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      2016   Phase 3   EUCTR2015-002276-25-AT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
      -   Phase 3   EUCTR2015-002276-25-NO   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Slovenia;South Africa;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2015-002276-25-GB   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Turkey;United Kingdom
Repatha 420 MG soluzione PER iniezione IN cartuccia
   AMGEN INC.
      2016   Phase 3   EUCTR2015-002276-25-IT   Australia;Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Czechia;Germany;Greece;Hungary;Italy;Netherlands;New Zealand;Norway;Poland;Portugal;Russian Federation;Slovenia;South Africa;Spain;Switzerland;Turkey;United Kingdom
Resmetirom
   Madrigal Pharmaceuticals, Inc.
      2017   Phase 2   NCT03038022   Denmark;Netherlands;Norway
RN316
   Pfizer
      2013   Phase 3   NCT01968980   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2014   Phase 3   EUCTR2013-002644-87-GB   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002644-87-ES   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002644-87-BG   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-NO   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-NL   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-IT   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002644-87-FI   Bulgaria;Canada;Finland;Italy;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
Rosuvastatin
   AstraZeneca
      2006   Phase 3   NCT00355615   Canada;Netherlands;Norway;Spain;United States
      2002   Phase 3   NCT00654602   -
      2002   Phase 3   NCT00654446   -
   Organon and Co
      2016   Phase 3   NCT02748057   Japan
   Regeneron Pharmaceuticals
      2012   Phase 3   NCT01709500   Czech Republic;Netherlands;Norway;United Kingdom
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002333-11-GB   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002333-11-ES   Australia;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002333-11-DE   Australia;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
Rosuvastatin 20MG
   AstraZeneca
      2015   Phase 3   NCT02434497   Belgium;Canada;Denmark;Israel;Malaysia;Taiwan
      2014   Phase 3   NCT02226198   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
Rosuvastatin calcium
   AstraZeneca
      2010   Phase 3   NCT01078675   Austria;Belgium;Canada;Netherlands;Norway;United States
   AstraZeneca AB
      2015   Phase 3   EUCTR2014-004746-99-DK   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      2015   Phase 3   EUCTR2014-004746-99-BE   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      2010   -   EUCTR2009-016492-29-NL   Belgium;Canada;Netherlands;Norway;United States
      2010   Phase 3   EUCTR2009-016492-29-BE   Belgium;Netherlands
      2010   -   EUCTR2009-016492-29-AT   Austria;Belgium;Netherlands
      2006   Phase 3   EUCTR2006-002616-96-NL   Netherlands;Spain
      -   Phase 3   EUCTR2014-004746-99-SE   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      -   -   EUCTR2009-016492-29-Outside-EU/EEA   Belgium;Canada;Netherlands;Norway;United States
      -   -   EUCTR2006-002616-96-Outside-EU/EEA   Canada;United States
   Regeneron Pharmaceuticals, Inc.
      2013   Phase 3   EUCTR2012-002344-24-GB   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002344-24-ES   Australia;Brazil;Canada;France;Germany;Italy;Mexico;New Zealand;Spain;United Kingdom;United States
      2013   -   EUCTR2012-002344-24-DE   Australia;Brazil;Canada;France;Germany;Italy;Mexico;Spain;United Kingdom;United States
Salivary sample
   Hospices Civils de Lyon
      2020   -   NCT04261803   France
SAR236553
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
   Sanofi-Aventis Recherche & Développement
      2018   Phase 3   EUCTR2017-002297-39-SI   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-NO   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-NL   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-IT   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-FR   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-ES   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-DK   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-BG   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-002297-39-AT   Argentina;Austria;Brazil;Bulgaria;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
   Sanofi-aventis recherche & développement
      2018   Phase 3   EUCTR2017-001903-60-SI   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-SE   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-NO   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-NL   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-IT   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-HU   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-FR   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-FI   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-ES   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-DK   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-DE   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-CZ   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-BG   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      2018   Phase 3   EUCTR2017-001903-60-AT   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
      -   Phase 3   EUCTR2017-001903-60-PL   Argentina;Austria;Brazil;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Italy;Lebanon;Mexico;Netherlands;Norway;Poland;Russian Federation;Slovenia;South Africa;Spain;Sweden;Taiwan;Turkey;United States
   sanofi-aventis Recherche & Développement
      2012   -   EUCTR2012-001096-37-NL   Canada;India;Netherlands;Russian Federation;South Africa;United States
      2012   -   EUCTR2011-005109-56-SE   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   Phase 3   EUCTR2011-005109-56-NO   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   Phase 3   EUCTR2011-005109-56-NL   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-GB   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-ES   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-DK   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-CZ   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2012   -   EUCTR2011-005109-56-AT   Austria;Canada;Czech Republic;Denmark;France;India;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
   sanofi-aventis recherche et développement
      2014   Phase 3   EUCTR2013-002572-40-RO   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-PT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-NO   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-HU   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-GB   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-FI   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DK   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-DE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-CZ   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BG   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-BE   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2014   Phase 3   EUCTR2013-002572-40-AT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-NL   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-IT   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2013   Phase 3   EUCTR2013-002572-40-ES   Argentina;Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Norway;Portugal;Romania;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
   sanofi-aventis recherche&developpement
      2017   Phase 2   EUCTR2015-003766-85-SE   Australia;Canada;Czech Republic;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden
      2016   Phase 2   EUCTR2015-003766-85-FR   Australia;Canada;Czech Republic;France;Israel;Norway;Russian Federation;Spain;Sweden
      2016   Phase 2   EUCTR2015-003766-85-ES   Australia;Canada;Czech Republic;France;Israel;Norway;Russian Federation;Spain;Sweden
      2016   Phase 2   EUCTR2015-003766-85-CZ   Australia;Canada;Czech Republic;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden
      -   Phase 2   EUCTR2015-003766-85-Outside-EU/EEA   Australia;Canada;Czech Republic;France;Israel;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden
SAR236553/REGN727
   Regeneron Pharmaceuticals, Inc.
      2015   Phase 3   EUCTR2014-001917-20-DE   Germany;United States
SFA muffin
   University of Oslo
      2016   -   NCT02729857   Norway
Sfingomielina
   CERENIS THERAPEUTICS SA
      2012   -   EUCTR2011-003998-28-IT   Canada;Italy;Netherlands;United Kingdom;United States
SHR-1209
   Jiangsu HengRui Medicine Co., Ltd.
      2021   Phase 3   NCT04885218   China
      2020   Phase 2   NCT04455581   -
SHR-1918
   Beijing Suncadia Pharmaceuticals Co., Ltd
      2025   Phase 2   NCT07133815   China
      2025   Phase 3   NCT06723652   China
      2023   Phase 2   NCT06009393   China
Simvastatin
   AstraZeneca
      2002   Phase 3   NCT00654446   -
   Organon and Co
      2002   Phase 3   NCT00552097   -
      2000   Phase 3   NCT03885921   -
      2000   Phase 3   NCT03884452   -
   Regeneron Pharmaceuticals
      2012   Phase 3   NCT01709500   Czech Republic;Netherlands;Norway;United Kingdom
   SCHERING-PLOUGH
      2005   -   EUCTR2004-002627-40-IT   Finland;Germany;Italy;Spain
   Sanofi
      2018   Phase 3   NCT03510715   Austria;Brazil;Canada;Denmark;France;Italy;Mexico;Netherlands;Norway;Russian Federation;Slovenia;Spain;Taiwan;Turkey;United States
   Schering-Plough Research Institute
      2005   Phase 3   EUCTR2004-002627-40-FI   Austria;Finland;Germany;Italy;Spain
      2005   Phase 3   EUCTR2004-002627-40-ES   Austria;Finland;Germany;Italy;Spain
      2005   -   EUCTR2004-002627-40-AT   Austria;Finland;Germany;Italy;Spain
   Schering-Plough Research Institute on behalf of MSP Singapore Company, LLC
      2005   -   EUCTR2004-002627-40-DE   Austria;Finland;Germany;Italy;Spain
Single intravenous (IV) dose OF human LOW density lipoprotein receptor (ldlr) gene therapy
   REGENXBIO Inc.
      2019   -   NCT04080050   Canada;Italy;Netherlands;United States
Sortis 10 MG filmtabletten
   Pfizer Inc. 235 East 42nd Street, New York, NY 10017, USA
      2009   -   EUCTR2008-006130-95-DE   Belgium;Canada;Germany;Greece;Hungary;Italy;Norway;Poland;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United States
Sortis 20 MG filmtabletten
   Pfizer Inc. 235 East 42nd Street, New York, NY 10017, USA
      2009   -   EUCTR2008-006130-95-DE   Belgium;Canada;Germany;Greece;Hungary;Italy;Norway;Poland;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United States
Sortis 40 MG filmtabletten
   Pfizer Inc. 235 East 42nd Street, New York, NY 10017, USA
      2009   -   EUCTR2008-006130-95-DE   Belgium;Canada;Germany;Greece;Hungary;Italy;Norway;Poland;Russian Federation;Slovakia;Spain;Switzerland;Turkey;United States
SOY protein diet
   Medical University of Vienna
      2009   -   NCT00924339   Austria
SPC5001
   Santaris Pharma A/S
      2011   Phase 1   NCT01350960   Netherlands
Sphingomyelin
   Cerenis Therapeutics
      2012   -   EUCTR2011-003998-28-NL   Canada;France;Italy;Netherlands;United Kingdom;United States
      2012   Phase 2   EUCTR2011-003998-28-GB   Canada;Italy;Netherlands;United Kingdom;United States
Standard lipid lowering therapy
   GWT-TUD GmbH
      2017   -   NCT03110432   Germany
Standard OF care
   Mayo Clinic
      2026   -   NCT07653555   United States
   The Medicines Company
      2016   Phase 2   NCT02963311   Netherlands;South Africa;United States
Statins
   Akeso
      2019   Phase 2   NCT03933293   China
   Sanofi
      2016   Phase 2   NCT02890992   Australia;Canada;Czech Republic;Czechia;France;Netherlands;Norway;Russian Federation;South Africa;Spain;Sweden;United States
Statins and ezetimibe
   University of Sao Paulo
      2007   -   NCT00475826   Brazil
Statins and/or ezetimibe
   Akeso
      2019   Phase 2   NCT04173793   China
Sunflower OIL
   Medical University of Vienna
      2008   -   NCT00924274   Austria
SYH2053 injection
   CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
      2026   Phase 3   NCT07465263   -
      2026   Phase 3   NCT07421297   China
SYH2070 injection DOSE1
   CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
      2026   Phase 2   NCT07591298   -
SYH2070 injection DOSE2
   CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
      2026   Phase 2   NCT07591298   -
TA-8995
   NewAmsterdam Pharma B.V.
      2023   Phase 3   EUCTR2021-005064-22-PL   Canada;Czech Republic;Czechia;Georgia;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005065-40-NL   China;Czech Republic;Czechia;Denmark;Georgia;Japan;Netherlands;Poland;United States
      2022   Phase 3   EUCTR2021-005065-40-DK   China;Czech Republic;Czechia;Denmark;Georgia;Japan;Netherlands;Poland;United States
      2022   Phase 3   EUCTR2021-005065-40-CZ   China;Czech Republic;Czechia;Denmark;Georgia;Japan;Netherlands;Poland;United States
      2022   Phase 3   EUCTR2021-005064-22-NL   Canada;Czech Republic;Czechia;Georgia;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005064-22-CZ   Canada;Czech Republic;Czechia;Georgia;Netherlands;Norway;Poland;South Africa;Spain;United Kingdom;United States
TAK-475
   Takeda Europe R&D Centre Ltd
      2006   -   EUCTR2005-003626-26-GB   United Kingdom
Torcetrapib (CP-529,414)/atorvastatin
      2005   -   EUCTR2004-004269-14-DK   Denmark;Iceland;Sweden
   Pfizer
      2005   Phase 3   EUCTR2004-004269-14-IS   Denmark;Iceland;Sweden
   Pfizer AB
      2005   -   EUCTR2004-004269-14-SE   Denmark;Iceland;Sweden
Torcetrapib/atorvastatin
   Pfizer
      2005   Phase 3   NCT00134511   Canada;South Africa;United States
      2005   Phase 3   NCT00134485   Australia;Canada;Denmark;France;Iceland;Norway;South Africa;Sweden;United States
      2003   Phase 3   NCT00136981   Canada;Czech Republic;Finland;France;Italy;Netherlands;South Africa;United States
Tredaptive
   Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
      2012   -   EUCTR2012-001443-49-GB   New Zealand;Norway;South Africa;United Kingdom
Verve-101
   Verve Therapeutics, Inc.
      2022   Phase 1   NCT05398029   New Zealand;United Kingdom
Verve-102
   Verve Therapeutics, Inc.
      2024   Phase 1   NCT06164730   Australia;Canada;Israel;New Zealand;United Kingdom;United States
Visit 1
   National Medical Research Center for Therapy and Preventive Medicine
      2020   -   NCT04656028   Russian Federation
Visit 2
   National Medical Research Center for Therapy and Preventive Medicine
      2020   -   NCT04656028   Russian Federation
Visit 3
   National Medical Research Center for Therapy and Preventive Medicine
      2020   -   NCT04656028   Russian Federation
Visit 4
   National Medical Research Center for Therapy and Preventive Medicine
      2020   -   NCT04656028   Russian Federation
VSA003
   Visirna Therapeutics HK Limited
      2024   Phase 3   NCT06712771   China
      2023   Phase 1   NCT05851066   China
Welchol
   Daiichi Sankyo Pharma Development
      2007   -   EUCTR2005-003511-75-CZ   Czech Republic;Hungary
      2006   Phase 4   EUCTR2005-003511-75-SK   Austria;Czech Republic;Hungary;Slovakia
      2006   -   EUCTR2005-003511-75-HU   Czech Republic;Hungary
   Sankyo Pharma Development (SPhD)
      2005   -   EUCTR2005-003511-75-AT   Austria;Czech Republic;Hungary
      -   Phase 4   EUCTR2005-003511-75-NO   Austria;Czech Republic;Hungary;Norway;Slovakia
Whole genome sequencing
   Nantes University Hospital
      2017   -   NCT03234127   France
YOLT-101
   First Affiliated Hospital Bengbu Medical College
      2024   Early Phase 1   NCT06461702   China
   RenJi Hospital
      2024   Early Phase 1   NCT06458010   China
ZD4522
   AstraZeneca AB
      2015   Phase 3   EUCTR2014-004746-99-DK   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      2015   Phase 3   EUCTR2014-004746-99-BE   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      2014   -   EUCTR2014-000972-24-SE   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
      2014   -   EUCTR2014-000972-24-NL   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
      2014   -   EUCTR2014-000972-24-DK   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
      2014   -   EUCTR2014-000972-24-DE   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2014-000972-24-BE   Australia;Belgium;Czech Republic;Denmark;Germany;Hong Kong;Israel;Netherlands;Norway;South Africa;Sweden;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2014-004746-99-SE   Belgium;Canada;Denmark;Germany;Israel;Lebanon;Malaysia;Netherlands;Sweden;Taiwan;United States
Zocor
   Schering-Plough Research Institute
      2005   Phase 3   EUCTR2004-002627-40-FI   Austria;Finland;Germany;Italy;Spain
      2005   Phase 3   EUCTR2004-002627-40-ES   Austria;Finland;Germany;Italy;Spain
      2005   -   EUCTR2004-002627-40-AT   Austria;Finland;Germany;Italy;Spain
Zocor 10 MG
   Schering-Plough Research Institute on behalf of MSP Singapore Company, LLC
      2005   -   EUCTR2004-002627-40-DE   Austria;Finland;Germany;Italy;Spain
Zocor 20MG
   Schering-Plough Research Institute on behalf of MSP Singapore Company, LLC
      2005   -   EUCTR2004-002627-40-DE   Austria;Finland;Germany;Italy;Spain
Zocor 40MG
   Schering-Plough Research Institute on behalf of MSP Singapore Company, LLC
      2005   -   EUCTR2004-002627-40-DE   Austria;Finland;Germany;Italy;Spain
Zodasiran
   Arrowhead Pharmaceuticals
      2026   Phase 3   NCT07473843   -
Zodasiran injection
   Arrowhead Pharmaceuticals
      2025   Phase 3   NCT07037771   Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Georgia;Germany;Israel;Japan;New Zealand;Saudi Arabia;South Africa;Spain;Sweden;Turkey (Türkiye);United States