Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
2	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
3	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
4	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
5	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
6	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
7	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D00443 💬	Spironolactone	[7] 58, 67, 86, 113, 210, 218, 225 💬
8	AMPK signaling pathway 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
9	AMPK signaling pathway 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
10	Apelin signaling pathway 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
11	Apelin signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
12	Bile secretion 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
13	Bile secretion 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
14	Calcium signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
15	Calcium signaling pathway 💬	[2] AGTR1, EDNRA 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
16	cAMP signaling pathway 💬	[1] EDNRA 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
17	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
18	cGMP-PKG signaling pathway 💬	[2] AGTR1, EDNRA 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
19	Chagas disease 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
20	Chagas disease 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
21	Chagas disease 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
22	Chemical carcinogenesis - receptor activation 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[4] 19, 66, 218, 238 💬
23	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
24	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
25	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
26	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
27	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
28	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
29	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
30	Cushing syndrome 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
31	Cushing syndrome 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
32	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
33	Diabetic cardiomyopathy 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
34	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
35	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
36	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
37	Endocrine and other factor-regulated calcium reabsorption 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[4] 19, 66, 218, 238 💬
38	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
39	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
40	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
41	Metabolic pathways 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
42	Metabolic pathways 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
43	Mineral absorption 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[4] 19, 66, 218, 238 💬
44	Neuroactive ligand-receptor interaction 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
45	Neuroactive ligand-receptor interaction 💬	[2] AGTR1, EDNRA 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
46	Parathyroid hormone synthesis, secretion and action 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[4] 19, 66, 218, 238 💬
47	Pathways in cancer 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
48	Pathways in cancer 💬	[2] AGTR1, EDNRA 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
49	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
50	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
51	Renin secretion 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
52	Renin secretion 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
53	Renin secretion 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
54	Renin secretion 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
55	Renin secretion 💬	[2] AGTR1, EDNRA 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
56	Renin-angiotensin system 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
57	Renin-angiotensin system 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
58	Renin-angiotensin system 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
59	Renin-angiotensin system 💬	[1] AGTR1 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬
60	Renin-angiotensin system 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
61	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
62	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
63	Tuberculosis 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[4] 19, 66, 218, 238 💬
64	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
65	Vascular smooth muscle contraction 💬	[2] AGTR1, EDNRA 💬	D11776 💬	Sparsentan	[3] 66, 218, 222 💬