Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
2 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
3 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
4 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
5 Aldosterone-regulated sodium reabsorption 💬
 [1] NR3C2 💬 D00443 💬 Spironolactone [7] 58, 67, 86, 113, 210, 218, 225 💬
6 Aldosterone-regulated sodium reabsorption 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D00649 💬 Amiloride [4] 13, 67, 225, 299 💬
7 Aldosterone-regulated sodium reabsorption 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D07447 💬 Amiloride [4] 13, 67, 225, 299 💬
8 Alzheimer disease 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
9 Alzheimer disease 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
10 Alzheimer disease 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
11 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
12 AMPK signaling pathway 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
13 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
14 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
15 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
16 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
17 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
18 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
19 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
20 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
21 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
22 Bile secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
23 Bile secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
24 Bile secretion 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
25 Bile secretion 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
26 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
27 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
28 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
29 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
30 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
31 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
32 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
33 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
34 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
35 Circadian entrainment 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
36 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
37 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
38 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
39 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
40 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
41 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
42 Collecting duct acid secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
43 Collecting duct acid secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
44 Complement and coagulation cascades 💬
 [1] F8 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
45 Complement and coagulation cascades 💬
 [1] F8 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
46 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
47 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
48 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
49 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
50 Gap junction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
51 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
52 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
53 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
54 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
55 Gastric acid secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
56 Gastric acid secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
57 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
58 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
59 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
60 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
61 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
62 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
63 Human papillomavirus infection 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
64 Human papillomavirus infection 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
65 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
66 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
67 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
68 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
69 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
70 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
71 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
72 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
73 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
74 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
75 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
76 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
77 Leishmaniasis 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
78 Leishmaniasis 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
79 Leishmaniasis 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
80 Long-term depression 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
81 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
82 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
83 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
84 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
85 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
86 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
87 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
88 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
89 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
90 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
91 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
92 Metabolic pathways 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
93 Metabolic pathways 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
94 Metabolic pathways 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
95 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
96 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
97 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
98 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
99 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
100 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
101 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
102 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
103 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
104 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
105 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
106 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [3] 67, 72, 225 💬
107 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
108 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
109 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
110 Nitrogen metabolism 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
111 Nitrogen metabolism 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
112 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
113 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
114 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
115 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
116 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
117 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
118 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
119 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
120 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
121 Oxytocin signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
122 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
123 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
124 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
125 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
126 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
127 Pancreatic secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
128 Pancreatic secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
129 Pathways in cancer 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
130 Pathways in cancer 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
131 Pathways in cancer 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
132 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
133 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
134 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
135 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
136 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
137 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [3] 67, 72, 225 💬
138 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
139 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
140 Platelet activation 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
141 Platelet activation 💬
 [1] PTGS1 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
142 Platelet activation 💬
 [1] PTGS1 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
143 Platelet activation 💬
 [1] PTGS1 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
144 Proximal tubule bicarbonate reclamation 💬
 [2] CA2, CA4 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
145 Proximal tubule bicarbonate reclamation 💬
 [2] CA2, CA4 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
146 Purine metabolism 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
147 Purine metabolism 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
148 Purine metabolism 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
149 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
150 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
151 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
152 Renin secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
153 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
154 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
155 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
156 Salivary secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
157 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
158 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
159 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
160 Small cell lung cancer 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
161 Small cell lung cancer 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
162 Small cell lung cancer 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
163 Taste transduction 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D00649 💬 Amiloride [4] 13, 67, 225, 299 💬
164 Taste transduction 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D07447 💬 Amiloride [4] 13, 67, 225, 299 💬
165 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
166 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
167 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
168 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
169 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
170 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
171 TNF signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
172 TNF signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
173 TNF signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
174 Vascular smooth muscle contraction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
175 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
176 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
177 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [3] 67, 72, 225 💬
178 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
179 VEGF signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
180 VEGF signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬

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