Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adipocytokine signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
2 Adipocytokine signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
4 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
5 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
6 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
7 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D01450 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D07552 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D00358 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D02086 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D08127 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
12 African trypanosomiasis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
13 African trypanosomiasis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
14 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
15 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
16 Alcoholic liver disease 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
17 Alcoholic liver disease 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
18 Aldosterone synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
19 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 D00718 💬 Flavoxate [1] 226 💬
20 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 D07961 💬 Flavoxate [1] 226 💬
21 Allograft rejection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
22 Allograft rejection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
23 Alzheimer disease 💬
 [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 D08441 💬 Propiverine [1] 226 💬
24 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
25 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
26 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
27 Alzheimer disease 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
28 Alzheimer disease 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
29 Alzheimer disease 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
30 Alzheimer disease 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
31 Amoebiasis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
32 Amoebiasis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
33 Amphetamine addiction 💬
 [2] CACNA1C, CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
34 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
35 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
36 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
37 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
38 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
39 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
40 Amyotrophic lateral sclerosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
41 Amyotrophic lateral sclerosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
42 Antifolate resistance 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
43 Antifolate resistance 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
44 Antigen processing and presentation 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
45 Antigen processing and presentation 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
46 Apelin signaling pathway 💬
 [1] PDE3B 💬 D00718 💬 Flavoxate [1] 226 💬
47 Apelin signaling pathway 💬
 [1] PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
48 Apoptosis 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
49 Apoptosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
50 Apoptosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
51 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
52 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
53 Arrhythmogenic right ventricular cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
54 Asthma 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
55 Asthma 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
56 Asthma 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
57 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
58 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
59 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
60 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
61 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
62 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
63 Breast cancer 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
64 Breast cancer 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
65 Breast cancer 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
66 Breast cancer 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
67 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
68 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
69 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
70 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
71 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
72 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
73 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
74 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
75 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
76 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
77 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
78 Calcium signaling pathway 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
79 Calcium signaling pathway 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
80 Calcium signaling pathway 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
81 Calcium signaling pathway 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
82 Calcium signaling pathway 💬
 [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM5 💬 D08441 💬 Propiverine [1] 226 💬
83 Calcium signaling pathway 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
84 Calcium signaling pathway 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [6]  6 , 72, 127, 193, 206, 226 💬
85 Calcium signaling pathway 💬
 [1] P2RX3 💬 D11349 💬 Gefapixant [2] 85, 226 💬
86 Calcium signaling pathway 💬
 [3] PDE1A, PDE1B, PDE1C 💬 D00718 💬 Flavoxate [1] 226 💬
87 Calcium signaling pathway 💬
 [3] PDE1A, PDE1B, PDE1C 💬 D07961 💬 Flavoxate [1] 226 💬
88 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
89 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
90 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
91 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
92 cAMP signaling pathway 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
93 cAMP signaling pathway 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
94 cAMP signaling pathway 💬
 [6] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2 💬 D08441 💬 Propiverine [1] 226 💬
95 cAMP signaling pathway 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [6]  6 , 72, 127, 193, 206, 226 💬
96 cAMP signaling pathway 💬
 [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00718 💬 Flavoxate [1] 226 💬
97 cAMP signaling pathway 💬
 [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D07961 💬 Flavoxate [1] 226 💬
98 Carbohydrate digestion and absorption 💬
 [1] CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
99 Cardiac muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
100 Cellular senescence 💬
 [1] CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
101 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
102 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
103 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
104 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D00514 💬 Dexmedetomidine [13]  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬
105 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D01205 💬 Dexmedetomidine [13]  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬
106 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
107 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
108 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
109 cGMP-PKG signaling pathway 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
110 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
111 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 D01340 💬 Naloxone [2]  6 , 226 💬
112 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 D08249 💬 Naloxone [2]  6 , 226 💬
113 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
114 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
115 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 D03783 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
116 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 D05312 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
117 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 D05462 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
118 cGMP-PKG signaling pathway 💬
 [3] PDE2A, PDE3A, PDE3B 💬 D00718 💬 Flavoxate [1] 226 💬
119 cGMP-PKG signaling pathway 💬
 [3] PDE2A, PDE3A, PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
120 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
121 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
122 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
123 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
124 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
125 Chagas disease 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
126 Chagas disease 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
127 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
128 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
129 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
130 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
131 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
132 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
133 Chemical carcinogenesis - receptor activation 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
134 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
135 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
136 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
137 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
138 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
139 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
140 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
141 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
142 Cholinergic synapse 💬
 [9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D08441 💬 Propiverine [1] 226 💬
143 Circadian entrainment 💬
 [2] CACNA1C, CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
144 Complement and coagulation cascades 💬
 [1] SERPINC1 💬 D07510 💬 Heparin [12] 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
145 Coronavirus disease - COVID-19 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
146 Coronavirus disease - COVID-19 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
147 Cortisol synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
148 Cortisol synthesis and secretion 💬
 [2] PDE8A, PDE8B 💬 D00718 💬 Flavoxate [1] 226 💬
149 Cortisol synthesis and secretion 💬
 [2] PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
150 Cushing syndrome 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
151 Cushing syndrome 💬
 [3] PDE11A, PDE8A, PDE8B 💬 D00718 💬 Flavoxate [1] 226 💬
152 Cushing syndrome 💬
 [3] PDE11A, PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
153 Cytokine-cytokine receptor interaction 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
154 Cytokine-cytokine receptor interaction 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
155 Cytokine-cytokine receptor interaction 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
156 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
157 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
158 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
159 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
160 Dilated cardiomyopathy 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
161 Dilated cardiomyopathy 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
162 Dopaminergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
163 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
164 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
165 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
166 Dopaminergic synapse 💬
 [1] SCN1A 💬 D01450 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
167 Dopaminergic synapse 💬
 [1] SCN1A 💬 D07552 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
168 Dopaminergic synapse 💬
 [1] SCN1A 💬 D00358 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
169 Dopaminergic synapse 💬
 [1] SCN1A 💬 D02086 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
170 Dopaminergic synapse 💬
 [1] SCN1A 💬 D08127 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
171 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
172 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
173 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
174 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
175 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
176 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
177 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
178 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
179 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
180 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
181 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
182 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
183 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
184 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
185 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
186 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
187 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
188 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
189 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
190 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
191 Epstein-Barr virus infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
192 Epstein-Barr virus infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
193 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
194 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
195 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
196 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
197 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
198 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
199 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
200 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
201 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01340 💬 Naloxone [2]  6 , 226 💬
202 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08249 💬 Naloxone [2]  6 , 226 💬
203 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
204 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
205 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D03783 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
206 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05312 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
207 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05462 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
208 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01355 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
209 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08623 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
210 Fc epsilon RI signaling pathway 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
211 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
212 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
213 Fluid shear stress and atherosclerosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
214 Fluid shear stress and atherosclerosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
215 GABAergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
216 Gap junction 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
217 Gap junction 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
218 Gap junction 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
219 Gastric acid secretion 💬
 [1] CHRM3 💬 D08441 💬 Propiverine [1] 226 💬
220 Glucagon signaling pathway 💬
 [1] PDE3B 💬 D00718 💬 Flavoxate [1] 226 💬
221 Glucagon signaling pathway 💬
 [1] PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
222 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
223 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
224 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
225 Glutamatergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
226 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
227 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
228 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
229 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
230 GnRH secretion 💬
 [1] ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
231 GnRH secretion 💬
 [1] ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
232 GnRH secretion 💬
 [1] ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
233 GnRH secretion 💬
 [1] ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
234 GnRH secretion 💬
 [1] ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
235 GnRH secretion 💬
 [1] ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
236 GnRH secretion 💬
 [1] ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
237 GnRH secretion 💬
 [1] ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
238 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
239 Graft-versus-host disease 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
240 Graft-versus-host disease 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
241 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
242 Hematopoietic cell lineage 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
243 Hematopoietic cell lineage 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
244 Hepatitis B 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
245 Hepatitis B 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
246 Hepatitis C 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
247 Hepatitis C 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
248 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
249 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
250 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
251 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
252 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
253 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
254 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
255 Human cytomegalovirus infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
256 Human cytomegalovirus infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
257 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
258 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
259 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
260 Human immunodeficiency virus 1 infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
261 Human immunodeficiency virus 1 infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
262 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
263 Human papillomavirus infection 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
264 Human papillomavirus infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
265 Human papillomavirus infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
266 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
267 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
268 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
269 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
270 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
271 Hypertrophic cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
272 Hypertrophic cardiomyopathy 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
273 Hypertrophic cardiomyopathy 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
274 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
275 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
276 IL-17 signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
277 IL-17 signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
278 Inflammatory bowel disease 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
279 Inflammatory bowel disease 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
280 Inflammatory mediator regulation of TRP channels 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
281 Inflammatory mediator regulation of TRP channels 💬
 [1] TRPV1 💬 D00250 💬 Capsaicin [5]  2 ,  6 , 19, 86, 226 💬
282 Influenza A 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
283 Influenza A 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
284 Insulin resistance 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
285 Insulin resistance 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
286 Insulin secretion 💬
 [5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM3 💬 D08441 💬 Propiverine [1] 226 💬
287 Insulin secretion 💬
 [1] SNAP25 💬 D00783 💬 Botulinum toxin type A [13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
288 Insulin signaling pathway 💬
 [1] PDE3B 💬 D00718 💬 Flavoxate [1] 226 💬
289 Insulin signaling pathway 💬
 [1] PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
290 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
291 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
292 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
293 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
294 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
295 Legionellosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
296 Legionellosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
297 Leishmaniasis 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
298 Leishmaniasis 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
299 Leishmaniasis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
300 Leishmaniasis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
301 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
302 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
303 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
304 Lipid and atherosclerosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
305 Lipid and atherosclerosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
306 Long-term potentiation 💬
 [1] CACNA1C 💬 D08441 💬 Propiverine [1] 226 💬
307 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
308 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
309 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
310 Malaria 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
311 Malaria 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
312 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
313 MAPK signaling pathway 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
314 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
315 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
316 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
317 MAPK signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
318 MAPK signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
319 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
320 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
321 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
322 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
323 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00718 💬 Flavoxate [1] 226 💬
324 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
325 Metabolic pathways 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
326 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
327 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
328 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
329 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
330 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
331 Morphine addiction 💬
 [1] OPRM1 💬 D01340 💬 Naloxone [2]  6 , 226 💬
332 Morphine addiction 💬
 [1] OPRM1 💬 D08249 💬 Naloxone [2]  6 , 226 💬
333 Morphine addiction 💬
 [1] OPRM1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
334 Morphine addiction 💬
 [1] OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
335 Morphine addiction 💬
 [1] OPRM1 💬 D03783 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
336 Morphine addiction 💬
 [1] OPRM1 💬 D05312 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
337 Morphine addiction 💬
 [1] OPRM1 💬 D05462 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
338 Morphine addiction 💬
 [1] OPRM1 💬 D01355 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
339 Morphine addiction 💬
 [1] OPRM1 💬 D08623 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
340 Morphine addiction 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00718 💬 Flavoxate [1] 226 💬
341 Morphine addiction 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
342 mTOR signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
343 mTOR signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
344 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
345 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
346 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
347 Natural killer cell mediated cytotoxicity 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
348 Natural killer cell mediated cytotoxicity 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
349 Necroptosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
350 Necroptosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
351 Neuroactive ligand-receptor interaction 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D00514 💬 Dexmedetomidine [13]  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬
352 Neuroactive ligand-receptor interaction 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D01205 💬 Dexmedetomidine [13]  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬
353 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
354 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
355 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
356 Neuroactive ligand-receptor interaction 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
357 Neuroactive ligand-receptor interaction 💬
 [1] CALCA 💬 D11055 💬 Fremanezumab [2] 124, 226 💬
358 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D08441 💬 Propiverine [1] 226 💬
359 Neuroactive ligand-receptor interaction 💬
 [2] CNR1, CNR2 💬 D10915 💬 Cannabidiol [19]  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
360 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00385 💬 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬
361 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00983 💬 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬
362 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00984 💬 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬
363 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00985 💬 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬
364 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D06216 💬 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298 💬
365 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 D01340 💬 Naloxone [2]  6 , 226 💬
366 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 D08249 💬 Naloxone [2]  6 , 226 💬
367 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
368 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
369 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 D03783 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
370 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 D05312 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
371 Neuroactive ligand-receptor interaction 💬
 [3] OPRD1, OPRK1, OPRM1 💬 D05462 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
372 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 D01355 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
373 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 D08623 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
374 Neuroactive ligand-receptor interaction 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [6]  6 , 72, 127, 193, 206, 226 💬
375 Neuroactive ligand-receptor interaction 💬
 [1] P2RX3 💬 D11349 💬 Gefapixant [2] 85, 226 💬
376 Neuroactive ligand-receptor interaction 💬
 [1] TRPV1 💬 D00250 💬 Capsaicin [5]  2 ,  6 , 19, 86, 226 💬
377 Neurotrophin signaling pathway 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
378 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
379 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
380 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
381 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
382 NOD-like receptor signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
383 NOD-like receptor signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
384 Non-alcoholic fatty liver disease 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
385 Non-alcoholic fatty liver disease 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
386 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 D00718 💬 Flavoxate [1] 226 💬
387 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 D07961 💬 Flavoxate [1] 226 💬
388 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
389 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
390 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
391 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
392 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
393 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
394 Osteoclast differentiation 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
395 Osteoclast differentiation 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
396 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
397 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
398 Oxytocin signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
399 Oxytocin signaling pathway 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [6]  6 , 72, 127, 193, 206, 226 💬
400 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
401 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
402 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
403 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
404 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
405 Pancreatic secretion 💬
 [1] CHRM3 💬 D08441 💬 Propiverine [1] 226 💬
406 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D00718 💬 Flavoxate [1] 226 💬
407 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D07961 💬 Flavoxate [1] 226 💬
408 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
409 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
410 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
411 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
412 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
413 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
414 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
415 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
416 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
417 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
418 Pathways in cancer 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
419 Pathways in cancer 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
420 Pathways of neurodegeneration - multiple diseases 💬
 [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 D08441 💬 Propiverine [1] 226 💬
421 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
422 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
423 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
424 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
425 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
426 Pathways of neurodegeneration - multiple diseases 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
427 Pathways of neurodegeneration - multiple diseases 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
428 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
429 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
430 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
431 Pertussis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
432 Pertussis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
433 Phospholipase D signaling pathway 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
434 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D08441 💬 Propiverine [1] 226 💬
435 PI3K-Akt signaling pathway 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
436 Platelet activation 💬
 [1] PTGS1 💬 D00813 💬 Ketorolac [2] 70, 226 💬
437 Platelet activation 💬
 [1] PTGS1 💬 D08104 💬 Ketorolac [2] 70, 226 💬
438 Prion disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
439 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
440 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
441 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
442 Prion disease 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
443 Prion disease 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
444 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 D00718 💬 Flavoxate [1] 226 💬
445 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
446 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
447 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
448 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
449 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
450 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
451 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
452 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
453 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
454 Proteoglycans in cancer 💬
 [1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
455 Proteoglycans in cancer 💬
 [1] ESR1 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
456 Proteoglycans in cancer 💬
 [1] ESR1 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
457 Proteoglycans in cancer 💬
 [1] ESR1 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
458 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
459 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
460 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
461 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
462 Proteoglycans in cancer 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
463 Proteoglycans in cancer 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
464 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
465 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
466 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
467 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
468 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00718 💬 Flavoxate [1] 226 💬
469 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
470 Purine metabolism 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
471 Purine metabolism 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
472 Rap1 signaling pathway 💬
 [1] CNR1 💬 D10915 💬 Cannabidiol [19]  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
473 Rap1 signaling pathway 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
474 Ras signaling pathway 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
475 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D08441 💬 Propiverine [1] 226 💬
476 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
477 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
478 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
479 Regulation of lipolysis in adipocytes 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
480 Regulation of lipolysis in adipocytes 💬
 [1] PDE3B 💬 D00718 💬 Flavoxate [1] 226 💬
481 Regulation of lipolysis in adipocytes 💬
 [1] PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
482 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
483 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
484 Renin secretion 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
485 Renin secretion 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
486 Renin secretion 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
487 Renin secretion 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
488 Renin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
489 Renin secretion 💬
 [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 D00718 💬 Flavoxate [1] 226 💬
490 Renin secretion 💬
 [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
491 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
492 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
493 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
494 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
495 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 D10915 💬 Cannabidiol [19]  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
496 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
497 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
498 Rheumatoid arthritis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
499 Rheumatoid arthritis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
500 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
501 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
502 Salivary secretion 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
503 Salivary secretion 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
504 Salivary secretion 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
505 Salivary secretion 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
506 Salivary secretion 💬
 [1] CHRM3 💬 D08441 💬 Propiverine [1] 226 💬
507 Salmonella infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
508 Salmonella infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
509 Serotonergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
510 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
511 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
512 Serotonergic synapse 💬
 [1] SLC6A4 💬 D00809 💬 Amitriptyline [4] 78, 97, 226, 299 💬
513 Serotonergic synapse 💬
 [1] SLC6A4 💬 D07448 💬 Amitriptyline [4] 78, 97, 226, 299 💬
514 Serotonergic synapse 💬
 [1] SLC6A4 💬 D00816 💬 Nortriptyline [2]  6 , 226 💬
515 Serotonergic synapse 💬
 [1] SLC6A4 💬 D08288 💬 Nortriptyline [2]  6 , 226 💬
516 Shigellosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
517 Shigellosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
518 Small cell lung cancer 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
519 Small cell lung cancer 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
520 Sphingolipid signaling pathway 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
521 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 D01340 💬 Naloxone [2]  6 , 226 💬
522 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 D08249 💬 Naloxone [2]  6 , 226 💬
523 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
524 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
525 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 D03783 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
526 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 D05312 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
527 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 D05462 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
528 Sphingolipid signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
529 Sphingolipid signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
530 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 D00809 💬 Amitriptyline [4] 78, 97, 226, 299 💬
531 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 D07448 💬 Amitriptyline [4] 78, 97, 226, 299 💬
532 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 D00816 💬 Nortriptyline [2]  6 , 226 💬
533 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 D08288 💬 Nortriptyline [2]  6 , 226 💬
534 Synaptic vesicle cycle 💬
 [1] SNAP25 💬 D00783 💬 Botulinum toxin type A [13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
535 Systemic lupus erythematosus 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
536 Systemic lupus erythematosus 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
537 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
538 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
539 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
540 T cell receptor signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
541 T cell receptor signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
542 Taste transduction 💬
 [2] CACNA1C, CHRM3 💬 D08441 💬 Propiverine [1] 226 💬
543 Taste transduction 💬
 [1] P2RX3 💬 D11349 💬 Gefapixant [2] 85, 226 💬
544 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 D00718 💬 Flavoxate [1] 226 💬
545 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 D07961 💬 Flavoxate [1] 226 💬
546 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D01450 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
547 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D07552 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
548 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D00358 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
549 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D02086 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
550 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D08127 💬 Lidocaine [13]  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
551 TGF-beta signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
552 TGF-beta signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
553 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
554 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
555 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
556 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
557 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
558 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
559 Thermogenesis 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
560 Thermogenesis 💬
 [1] CNR1 💬 D10915 💬 Cannabidiol [19]  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
561 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
562 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
563 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
564 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
565 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
566 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
567 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
568 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
569 Tight junction 💬
 [1] CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
570 TNF signaling pathway 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
571 TNF signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
572 TNF signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
573 TNF signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
574 Toll-like receptor signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
575 Toll-like receptor signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
576 Toxoplasmosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
577 Toxoplasmosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
578 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
579 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
580 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
581 Tuberculosis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
582 Tuberculosis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
583 Type I diabetes mellitus 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
584 Type I diabetes mellitus 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
585 Type II diabetes mellitus 💬
 [2] CACNA1C, CACNA1D 💬 D08441 💬 Propiverine [1] 226 💬
586 Type II diabetes mellitus 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
587 Type II diabetes mellitus 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
588 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
589 Vascular smooth muscle contraction 💬
 [1] CALCA 💬 D11055 💬 Fremanezumab [2] 124, 226 💬
590 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
591 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
592 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
593 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
594 VEGF signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
595 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
596 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
597 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
598 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
599 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
600 Yersinia infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
601 Yersinia infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬

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