Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [1] DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
2 Alcoholism 💬
 [1] DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
3 Alcoholism 💬
 [1] DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
4 Alcoholism 💬
 [1] DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
5 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00270 💬 Chlorpromazine [1] 254 💬
6 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00789 💬 Chlorpromazine [1] 254 💬
7 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D03274 💬 Chlorpromazine [1] 254 💬
8 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D04034 💬 Chlorpromazine [1] 254 💬
9 Biosynthesis of cofactors 💬
 [1] ALAS1 💬 D11702 💬 Givosiran [1] 254 💬
10 Biosynthesis of cofactors 💬
 [2] ALAS1, ALAS2 💬 D10003 💬 Hemin [1] 254 💬
11 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 D00270 💬 Chlorpromazine [1] 254 💬
12 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 D00789 💬 Chlorpromazine [1] 254 💬
13 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 D03274 💬 Chlorpromazine [1] 254 💬
14 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 D04034 💬 Chlorpromazine [1] 254 💬
15 Calcium signaling pathway 💬
 [1] HRH2 💬 D00295 💬 Cimetidine [2]  2 , 254 💬
16 Calcium signaling pathway 💬
 [1] HRH2 💬 D03503 💬 Cimetidine [2]  2 , 254 💬
17 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
18 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
19 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
20 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
21 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D00270 💬 Chlorpromazine [1] 254 💬
22 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D00789 💬 Chlorpromazine [1] 254 💬
23 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D03274 💬 Chlorpromazine [1] 254 💬
24 cGMP-PKG signaling pathway 💬
 [3] ADRA2A, ADRA2B, ADRA2C 💬 D04034 💬 Chlorpromazine [1] 254 💬
25 Chemical carcinogenesis - reactive oxygen species 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
26 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00270 💬 Chlorpromazine [1] 254 💬
27 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00789 💬 Chlorpromazine [1] 254 💬
28 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D03274 💬 Chlorpromazine [1] 254 💬
29 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D04034 💬 Chlorpromazine [1] 254 💬
30 Cocaine addiction 💬
 [1] DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
31 Cocaine addiction 💬
 [1] DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
32 Cocaine addiction 💬
 [1] DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
33 Cocaine addiction 💬
 [1] DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
34 Dopaminergic synapse 💬
 [1] DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
35 Dopaminergic synapse 💬
 [1] DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
36 Dopaminergic synapse 💬
 [1] DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
37 Dopaminergic synapse 💬
 [1] DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
38 Ferroptosis 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
39 Fluid shear stress and atherosclerosis 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
40 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 D00270 💬 Chlorpromazine [1] 254 💬
41 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 D00789 💬 Chlorpromazine [1] 254 💬
42 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 D03274 💬 Chlorpromazine [1] 254 💬
43 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 D04034 💬 Chlorpromazine [1] 254 💬
44 Gastric acid secretion 💬
 [1] CHRM3 💬 D00270 💬 Chlorpromazine [1] 254 💬
45 Gastric acid secretion 💬
 [1] CHRM3 💬 D00789 💬 Chlorpromazine [1] 254 💬
46 Gastric acid secretion 💬
 [1] CHRM3 💬 D03274 💬 Chlorpromazine [1] 254 💬
47 Gastric acid secretion 💬
 [1] CHRM3 💬 D04034 💬 Chlorpromazine [1] 254 💬
48 Gastric acid secretion 💬
 [1] HRH2 💬 D00295 💬 Cimetidine [2]  2 , 254 💬
49 Gastric acid secretion 💬
 [1] HRH2 💬 D03503 💬 Cimetidine [2]  2 , 254 💬
50 Glycine, serine and threonine metabolism 💬
 [1] ALAS1 💬 D11702 💬 Givosiran [1] 254 💬
51 Glycine, serine and threonine metabolism 💬
 [2] ALAS1, ALAS2 💬 D10003 💬 Hemin [1] 254 💬
52 Hepatocellular carcinoma 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
53 HIF-1 signaling pathway 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
54 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 D00270 💬 Chlorpromazine [1] 254 💬
55 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 D00789 💬 Chlorpromazine [1] 254 💬
56 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 D03274 💬 Chlorpromazine [1] 254 💬
57 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 D04034 💬 Chlorpromazine [1] 254 💬
58 Insulin secretion 💬
 [1] CHRM3 💬 D00270 💬 Chlorpromazine [1] 254 💬
59 Insulin secretion 💬
 [1] CHRM3 💬 D00789 💬 Chlorpromazine [1] 254 💬
60 Insulin secretion 💬
 [1] CHRM3 💬 D03274 💬 Chlorpromazine [1] 254 💬
61 Insulin secretion 💬
 [1] CHRM3 💬 D04034 💬 Chlorpromazine [1] 254 💬
62 Melanogenesis 💬
 [1] MC1R 💬 D10511 💬 Afamelanotide [3] 159, 161, 254 💬
63 Metabolic pathways 💬
 [1] ALAS1 💬 D11702 💬 Givosiran [1] 254 💬
64 Metabolic pathways 💬
 [2] ALAS1, ALAS2 💬 D10003 💬 Hemin [1] 254 💬
65 Metabolic pathways 💬
 [2] HMOX1, HMOX2 💬 D05922 💬 Stannsoporfin [1] 254 💬
66 MicroRNAs in cancer 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
67 Mineral absorption 💬
 [2] HMOX1, HMOX2 💬 D05922 💬 Stannsoporfin [1] 254 💬
68 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 D00270 💬 Chlorpromazine [1] 254 💬
69 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 D00789 💬 Chlorpromazine [1] 254 💬
70 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 D03274 💬 Chlorpromazine [1] 254 💬
71 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 D04034 💬 Chlorpromazine [1] 254 💬
72 Neuroactive ligand-receptor interaction 💬
 [1] HRH2 💬 D00295 💬 Cimetidine [2]  2 , 254 💬
73 Neuroactive ligand-receptor interaction 💬
 [1] HRH2 💬 D03503 💬 Cimetidine [2]  2 , 254 💬
74 Neuroactive ligand-receptor interaction 💬
 [1] MC1R 💬 D10511 💬 Afamelanotide [3] 159, 161, 254 💬
75 Pancreatic secretion 💬
 [1] CHRM3 💬 D00270 💬 Chlorpromazine [1] 254 💬
76 Pancreatic secretion 💬
 [1] CHRM3 💬 D00789 💬 Chlorpromazine [1] 254 💬
77 Pancreatic secretion 💬
 [1] CHRM3 💬 D03274 💬 Chlorpromazine [1] 254 💬
78 Pancreatic secretion 💬
 [1] CHRM3 💬 D04034 💬 Chlorpromazine [1] 254 💬
79 Parkinson disease 💬
 [1] DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
80 Parkinson disease 💬
 [1] DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
81 Parkinson disease 💬
 [1] DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
82 Parkinson disease 💬
 [1] DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
83 Pathways in cancer 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
84 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00270 💬 Chlorpromazine [1] 254 💬
85 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00789 💬 Chlorpromazine [1] 254 💬
86 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D03274 💬 Chlorpromazine [1] 254 💬
87 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D04034 💬 Chlorpromazine [1] 254 💬
88 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00270 💬 Chlorpromazine [1] 254 💬
89 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00789 💬 Chlorpromazine [1] 254 💬
90 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D03274 💬 Chlorpromazine [1] 254 💬
91 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D04034 💬 Chlorpromazine [1] 254 💬
92 Porphyrin metabolism 💬
 [1] ALAS1 💬 D11702 💬 Givosiran [1] 254 💬
93 Porphyrin metabolism 💬
 [2] ALAS1, ALAS2 💬 D10003 💬 Hemin [1] 254 💬
94 Porphyrin metabolism 💬
 [2] HMOX1, HMOX2 💬 D05922 💬 Stannsoporfin [1] 254 💬
95 Rap1 signaling pathway 💬
 [1] DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
96 Rap1 signaling pathway 💬
 [1] DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
97 Rap1 signaling pathway 💬
 [1] DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
98 Rap1 signaling pathway 💬
 [1] DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
99 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00270 💬 Chlorpromazine [1] 254 💬
100 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00789 💬 Chlorpromazine [1] 254 💬
101 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D03274 💬 Chlorpromazine [1] 254 💬
102 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D04034 💬 Chlorpromazine [1] 254 💬
103 Salivary secretion 💬
 [1] CHRM3 💬 D00270 💬 Chlorpromazine [1] 254 💬
104 Salivary secretion 💬
 [1] CHRM3 💬 D00789 💬 Chlorpromazine [1] 254 💬
105 Salivary secretion 💬
 [1] CHRM3 💬 D03274 💬 Chlorpromazine [1] 254 💬
106 Salivary secretion 💬
 [1] CHRM3 💬 D04034 💬 Chlorpromazine [1] 254 💬
107 Serotonergic synapse 💬
 [3] HTR2A, HTR2B, HTR2C 💬 D00270 💬 Chlorpromazine [1] 254 💬
108 Serotonergic synapse 💬
 [3] HTR2A, HTR2B, HTR2C 💬 D00789 💬 Chlorpromazine [1] 254 💬
109 Serotonergic synapse 💬
 [3] HTR2A, HTR2B, HTR2C 💬 D03274 💬 Chlorpromazine [1] 254 💬
110 Serotonergic synapse 💬
 [3] HTR2A, HTR2B, HTR2C 💬 D04034 💬 Chlorpromazine [1] 254 💬
111 Taste transduction 💬
 [1] CHRM3 💬 D00270 💬 Chlorpromazine [1] 254 💬
112 Taste transduction 💬
 [1] CHRM3 💬 D00789 💬 Chlorpromazine [1] 254 💬
113 Taste transduction 💬
 [1] CHRM3 💬 D03274 💬 Chlorpromazine [1] 254 💬
114 Taste transduction 💬
 [1] CHRM3 💬 D04034 💬 Chlorpromazine [1] 254 💬

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