Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 2 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 4 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 5 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 6 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 7 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 8 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 9 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 10 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 11 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 12 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 13 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 14 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 15 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 16 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 17 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 18 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 19 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 20 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 21 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 22 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 23 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 24 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 25 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D03492 D03492 💬 |
Cibenzoline | 058 [1] 58 💬 |
| 26 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D11155 D11155 💬 |
Eleclazine | 058 [1] 58 💬 |
| 27 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 28 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 29 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 30 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 31 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 32 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 33 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 34 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 35 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 36 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 37 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 38 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 39 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 40 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 41 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 42 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 43 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 44 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 45 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 46 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 47 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 48 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 49 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 50 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 51 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 52 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 53 | Aldosterone-regulated sodium reabsorption 💬 Related to 12 target genes, 12 drugs (DrugBank) and 23 diseases in DDrare |
NR3C2 [1] NR3C2 💬 |
D00443 D00443 💬 |
Spironolactone | 058 [7] 58, 67, 86, 113, 210, 218, 225 💬 |
| 54 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 55 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 56 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 57 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 58 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 59 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 60 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 61 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MME [1] MME 💬 |
D10225 D10225 💬 |
Sacubitril | 058 [1] 58 💬 |
| 62 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 63 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 64 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 65 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 66 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 67 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 68 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 69 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 70 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 71 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 72 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 73 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 74 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 75 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 76 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 77 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 78 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 79 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 80 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 81 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 82 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 83 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 84 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 85 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 86 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 87 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 88 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 89 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 90 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 91 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 92 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 93 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 94 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 95 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 96 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 97 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 98 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 99 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
IL10 [1] IL10 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 100 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 101 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 102 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 103 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 104 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 105 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 106 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 107 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 108 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 109 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 110 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 111 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 112 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 113 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 114 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 115 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 116 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 117 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 118 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 119 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 120 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 121 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 122 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 123 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 124 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 125 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 126 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 127 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 128 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 129 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 130 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 131 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 132 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA2A 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 133 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 134 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 135 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 136 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 137 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 138 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 139 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 140 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 141 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 142 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 143 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 144 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 145 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 146 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 147 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 148 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 149 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 150 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 151 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 152 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 153 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 154 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 155 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 156 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 157 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 158 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 159 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 160 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 161 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 162 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 163 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 164 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 165 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL1A [2] IL1A, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 166 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 167 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 168 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 169 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 170 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 171 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 172 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 173 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 174 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 175 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 176 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 177 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 178 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 179 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 180 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 181 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 182 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 183 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 184 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 185 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 186 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 187 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 188 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 189 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 190 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 191 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 192 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 193 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 194 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 195 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 196 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 197 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 198 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 199 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 200 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 201 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 202 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 203 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 204 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 205 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 206 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 207 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 208 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 209 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 210 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CCL2 [1] CCL2 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 211 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 212 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 213 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 214 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 215 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 216 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 217 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 218 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 219 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 220 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 221 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 222 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 223 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 224 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 225 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 226 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 227 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 228 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 229 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 230 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 231 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 232 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 233 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 234 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 235 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 236 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 237 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 238 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 239 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 240 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 241 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 242 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 243 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 244 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 245 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 246 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 247 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 248 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 249 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 250 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 251 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 252 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 253 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 254 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 255 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 256 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CCL2 [6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 257 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL1B [2] IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 258 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 259 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 260 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 261 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 262 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 263 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 264 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
CPT1B [2] CPT1B, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 265 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
CPT1B [2] CPT1B, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 266 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 267 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 268 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 269 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 270 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 271 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 272 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 273 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 274 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 275 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 276 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 277 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 278 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 279 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 280 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 281 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 282 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 283 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 284 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 285 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 286 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 287 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 288 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 289 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 290 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 291 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
SCN1A [1] SCN1A 💬 |
D03492 D03492 💬 |
Cibenzoline | 058 [1] 58 💬 |
| 292 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
SCN1A [1] SCN1A 💬 |
D11155 D11155 💬 |
Eleclazine | 058 [1] 58 💬 |
| 293 | Drug metabolism - cytochrome P450 💬 Related to 5 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 294 | Drug metabolism - cytochrome P450 💬 Related to 5 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 295 | Drug metabolism - cytochrome P450 💬 Related to 5 target genes, 8 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 296 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 297 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 298 | Fatty acid degradation 💬 Related to 7 target genes, 2 drugs (DrugBank) and 3 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 299 | Fatty acid degradation 💬 Related to 7 target genes, 2 drugs (DrugBank) and 3 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 300 | Fatty acid metabolism 💬 Related to 4 target genes, 1 drug (DrugBank) and 2 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 301 | Fatty acid metabolism 💬 Related to 4 target genes, 1 drug (DrugBank) and 2 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 302 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 303 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
CCL2 [4] CCL2, IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 304 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IL10 [2] IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 305 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 306 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 307 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 308 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 309 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 310 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 311 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 312 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 313 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 314 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 315 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 316 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 317 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 318 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 319 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 320 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 321 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 322 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 323 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 324 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 325 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 326 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 327 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 328 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 329 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 10 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 330 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 10 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 331 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 10 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 332 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 333 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 334 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 335 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 336 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 337 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 338 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 339 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 340 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 341 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 342 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 343 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 344 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 345 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 346 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 347 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 348 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 349 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 350 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 351 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
MME [1] MME 💬 |
D10225 D10225 💬 |
Sacubitril | 058 [1] 58 💬 |
| 352 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 353 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 354 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 355 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 356 | Histidine metabolism 💬 Related to 2 target genes, 7 drugs (DrugBank) and 8 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 357 | Histidine metabolism 💬 Related to 2 target genes, 7 drugs (DrugBank) and 8 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 358 | Histidine metabolism 💬 Related to 2 target genes, 7 drugs (DrugBank) and 8 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 359 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 360 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 361 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 362 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 363 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 364 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 365 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 366 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 367 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 368 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 369 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 370 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 371 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 372 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 373 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 374 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 375 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 376 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 377 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 378 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 379 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 380 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1B [1] IL1B 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 381 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 382 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
CPT1A [2] CPT1A, CPT1B 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 383 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
CPT1A [2] CPT1A, CPT1B 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 384 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 385 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 386 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 387 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 388 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 389 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 390 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL10 [2] IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 391 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
IL10 [2] IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 392 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 393 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 394 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 395 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 396 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
IL10 [4] IL10, IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 397 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 398 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 399 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 400 | Long-term depression 💬 Related to 12 target genes, 17 drugs (DrugBank) and 33 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 401 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 402 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 403 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 404 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 405 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 406 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 407 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 408 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 409 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 410 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 411 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 412 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 413 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 414 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 415 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 416 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 417 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1A [3] IL1A, IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 418 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 419 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 420 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 421 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 422 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 423 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 424 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 425 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 426 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 427 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 428 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 429 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 430 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 431 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 432 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADORA1 [4] ADORA1, ADORA2A, ADORA2B, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 433 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 434 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 435 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 436 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 437 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 438 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 439 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 440 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 441 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 442 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 443 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 444 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 445 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 446 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 447 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 448 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 449 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
IL1B [2] IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 450 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 451 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 452 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 453 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 454 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 455 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 456 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 457 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 458 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 459 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 460 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 461 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 462 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 463 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 464 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 465 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 466 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 467 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 468 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 469 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 470 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 471 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 472 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 473 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 474 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 475 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 476 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 477 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 478 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 479 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 480 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 481 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 482 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 483 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 484 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 485 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 486 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 487 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 488 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 16 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 489 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 16 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 490 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 16 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 491 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 492 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 493 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 494 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 495 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 496 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 497 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 498 | PPAR signaling pathway 💬 Related to 10 target genes, 13 drugs (DrugBank) and 31 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 499 | PPAR signaling pathway 💬 Related to 10 target genes, 13 drugs (DrugBank) and 31 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 500 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 501 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 502 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 503 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 504 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 505 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 506 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 507 | Protein digestion and absorption 💬 Related to 7 target genes, 7 drugs (DrugBank) and 12 diseases in DDrare |
MME [1] MME 💬 |
D10225 D10225 💬 |
Sacubitril | 058 [1] 58 💬 |
| 508 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 509 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 510 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 511 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 512 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 513 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 514 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 515 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 516 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 517 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 518 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 519 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 520 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 521 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 522 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 523 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 524 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 525 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 526 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 527 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 528 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 529 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 530 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 531 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 532 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 533 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 534 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 535 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 536 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 537 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 538 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 539 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 540 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 541 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 542 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 543 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 544 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 545 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 546 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 547 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 548 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 549 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 550 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 551 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 552 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 553 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 554 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 555 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
MME [1] MME 💬 |
D10225 D10225 💬 |
Sacubitril | 058 [1] 58 💬 |
| 556 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 557 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 558 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 559 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 560 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 561 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 562 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 563 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 564 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 565 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 566 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 567 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 568 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 569 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 570 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 571 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 572 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 573 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 574 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 575 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 576 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 577 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 578 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 579 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 580 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 581 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 582 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 583 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 584 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 585 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 586 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
IL1B [2] IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 587 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 588 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 589 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 590 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
IL10 [1] IL10 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 591 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 592 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 593 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 594 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 595 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 596 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 597 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 598 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 599 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D03492 D03492 💬 |
Cibenzoline | 058 [1] 58 💬 |
| 600 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D11155 D11155 💬 |
Eleclazine | 058 [1] 58 💬 |
| 601 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 602 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 603 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 604 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 605 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [2] IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 606 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 607 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 608 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 609 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 610 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 611 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 612 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 613 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 614 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 615 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 616 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 617 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 618 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 619 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 620 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 621 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 622 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 623 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 13 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 624 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 625 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 626 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 627 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 628 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 629 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 630 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 631 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 632 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G [1] CACNA1G 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 633 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G [1] CACNA1G 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 634 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 635 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 636 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 637 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 19 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 638 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 639 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 640 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 641 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 642 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 643 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 644 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 645 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 646 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 647 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 648 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 649 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 650 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 651 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 652 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 653 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 654 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 655 | Viral myocarditis 💬 Related to 30 target genes, 20 drugs (DrugBank) and 47 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 656 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
CCL2 [4] CCL2, IL10, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 657 | Wnt signaling pathway 💬 Related to 8 target genes, 8 drugs (DrugBank) and 60 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 658 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |