Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [2] PML, RARA 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
2 Adherens junction 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
3 Adherens junction 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
4 Adherens junction 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
5 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
6 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
7 Adipocytokine signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
9 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
10 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
11 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
12 Alcoholism 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
13 Alcoholism 💬
 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
14 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
15 Aldosterone synthesis and secretion 💬
 [1] CYP11B2 💬 D11061 💬 Osilodrostat [1] 75 💬
16 Aldosterone synthesis and secretion 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [15]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
17 Aldosterone-regulated sodium reabsorption 💬
 [1] NR3C2 💬 D01115 💬 Eplerenone [4] 75, 113, 210, 215 💬
18 Amphetamine addiction 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
19 AMPK signaling pathway 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
20 AMPK signaling pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
21 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
22 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
23 Amyotrophic lateral sclerosis 💬
 [1] HDAC6 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
24 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
25 Apelin signaling pathway 💬
 [2] HDAC4, HDAC5 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
26 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
27 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
28 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
29 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
30 Bile secretion 💬
 [1] RXRA 💬 D03106 💬 Bexarotene [2] 13, 75 💬
31 Bladder cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
32 Bladder cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
33 Bladder cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
34 Breast cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
35 Breast cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
36 Breast cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
37 Breast cancer 💬
 [1] PGR 💬 D00585 💬 Mifepristone [1] 75 💬
38 Calcium signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
39 Calcium signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
40 Calcium signaling pathway 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
41 Calcium signaling pathway 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
42 cAMP signaling pathway 💬
 [2] CRHR1, CRHR2 💬 D03905 💬 Corticorelin [2] 75, 205 💬
43 cAMP signaling pathway 💬
 [2] CRHR1, CRHR2 💬 D03592 💬 Corticorelin ovine triflutate [1] 75 💬
44 cAMP signaling pathway 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
45 cAMP signaling pathway 💬
 [1] GLP1R 💬 D06404 💬 Liraglutide [3]  6 , 75, 193 💬
46 cAMP signaling pathway 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [15]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
47 cAMP signaling pathway 💬
 [3] SSTR1, SSTR2, SSTR5 💬 D10147 💬 Pasireotide [3] 67, 74, 75 💬
48 cAMP signaling pathway 💬
 [1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
49 cAMP signaling pathway 💬
 [1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
50 Cell cycle 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
51 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
52 Central carbon metabolism in cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
53 Central carbon metabolism in cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
54 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
55 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
56 Chemical carcinogenesis - reactive oxygen species 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
57 Chemical carcinogenesis - reactive oxygen species 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
58 Chemical carcinogenesis - reactive oxygen species 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
59 Chemical carcinogenesis - receptor activation 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
60 Chemical carcinogenesis - receptor activation 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
61 Chemical carcinogenesis - receptor activation 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
62 Chemical carcinogenesis - receptor activation 💬
 [1] PGR 💬 D00585 💬 Mifepristone [1] 75 💬
63 Chemical carcinogenesis - receptor activation 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
64 Chemical carcinogenesis - receptor activation 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
65 Choline metabolism in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
66 Choline metabolism in cancer 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
67 Choline metabolism in cancer 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
68 Chronic myeloid leukemia 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
69 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
70 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
71 Cocaine addiction 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
72 Colorectal cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
73 Colorectal cancer 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
74 Colorectal cancer 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
75 Complement and coagulation cascades 💬
 [1] F10 💬 D07086 💬 Rivaroxaban [5] 46, 49, 75, 91, 210 💬
76 Complement and coagulation cascades 💬
 [1] F8 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
77 Complement and coagulation cascades 💬
 [1] F8 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
78 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
79 Coronavirus disease - COVID-19 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
80 Coronavirus disease - COVID-19 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
81 Coronavirus disease - COVID-19 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
82 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
83 Cortisol synthesis and secretion 💬
 [1] CYP11B1 💬 D00410 💬 Metyrapone [2] 75, 193 💬
84 Cortisol synthesis and secretion 💬
 [1] CYP11B1 💬 D05019 💬 Metyrapone [2] 75, 193 💬
85 Cortisol synthesis and secretion 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
86 Cortisol synthesis and secretion 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [15]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
87 Cushing syndrome 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
88 Cushing syndrome 💬
 [2] CRHR1, CRHR2 💬 D03905 💬 Corticorelin [2] 75, 205 💬
89 Cushing syndrome 💬
 [2] CRHR1, CRHR2 💬 D03592 💬 Corticorelin ovine triflutate [1] 75 💬
90 Cushing syndrome 💬
 [1] CYP11B1 💬 D00410 💬 Metyrapone [2] 75, 193 💬
91 Cushing syndrome 💬
 [1] CYP11B1 💬 D05019 💬 Metyrapone [2] 75, 193 💬
92 Cushing syndrome 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
93 Cushing syndrome 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
94 Cushing syndrome 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
95 Cushing syndrome 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
96 Cushing syndrome 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [15]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
97 Cytokine-cytokine receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
98 Cytokine-cytokine receptor interaction 💬
 [1] PRL 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
99 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
100 Dopaminergic synapse 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
101 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
102 EGFR tyrosine kinase inhibitor resistance 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
103 EGFR tyrosine kinase inhibitor resistance 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
104 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
105 Endocrine resistance 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
106 Endocrine resistance 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
107 Endocrine resistance 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
108 Endocytosis 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
109 Endocytosis 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
110 Endocytosis 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
111 Endocytosis 💬
 [1] PML 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
112 Endometrial cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
113 Endometrial cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
114 Endometrial cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
115 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
116 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
117 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
118 Epstein-Barr virus infection 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
119 ErbB signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
120 ErbB signaling pathway 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
121 ErbB signaling pathway 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
122 Estrogen signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
123 Estrogen signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
124 Estrogen signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
125 Estrogen signaling pathway 💬
 [1] PGR 💬 D00585 💬 Mifepristone [1] 75 💬
126 Estrogen signaling pathway 💬
 [1] RARA 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
127 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
128 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
129 Focal adhesion 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
130 Focal adhesion 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
131 Focal adhesion 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
132 FoxO signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
133 FoxO signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
134 FoxO signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
135 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
136 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
137 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
138 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
139 Gap junction 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
140 Gap junction 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
141 Gap junction 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
142 Gap junction 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
143 Gastric acid secretion 💬
 [1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
144 Gastric acid secretion 💬
 [1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
145 Gastric acid secretion 💬
 [1] SSTR2 💬 D10147 💬 Pasireotide [3] 67, 74, 75 💬
146 Gastric cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
147 Gastric cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
148 Gastric cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
149 Gastric cancer 💬
 [1] RARB 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
150 Gastric cancer 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
151 Glioma 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
152 Glioma 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
153 Glioma 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
154 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
155 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
156 GnRH signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
157 GnRH signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
158 GnRH signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
159 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
160 Growth hormone synthesis, secretion and action 💬
 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 D10147 💬 Pasireotide [3] 67, 74, 75 💬
161 Growth hormone synthesis, secretion and action 💬
 [1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
162 Growth hormone synthesis, secretion and action 💬
 [1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
163 Hepatitis C 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
164 Hepatitis C 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
165 Hepatitis C 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
166 Hepatitis C 💬
 [1] RXRA 💬 D03106 💬 Bexarotene [2] 13, 75 💬
167 Hepatocellular carcinoma 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
168 Hepatocellular carcinoma 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
169 Hepatocellular carcinoma 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
170 Herpes simplex virus 1 infection 💬
 [1] PML 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
171 HIF-1 signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
172 HIF-1 signaling pathway 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
173 HIF-1 signaling pathway 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
174 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
175 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
176 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
177 Human papillomavirus infection 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
178 Human papillomavirus infection 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
179 Human papillomavirus infection 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
180 Human papillomavirus infection 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
181 Huntington disease 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
182 Huntington disease 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
183 Huntington disease 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
184 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
185 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
186 Influenza A 💬
 [1] PML 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
187 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
188 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
189 Insulin secretion 💬
 [1] GLP1R 💬 D06404 💬 Liraglutide [3]  6 , 75, 193 💬
190 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
191 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
192 JAK-STAT signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
193 JAK-STAT signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
194 JAK-STAT signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
195 JAK-STAT signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
196 JAK-STAT signaling pathway 💬
 [1] PRL 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
197 Lipid and atherosclerosis 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
198 Lipid and atherosclerosis 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
199 Lipid and atherosclerosis 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
200 Long-term depression 💬
 [1] CRHR1 💬 D03905 💬 Corticorelin [2] 75, 205 💬
201 Long-term depression 💬
 [1] CRHR1 💬 D03592 💬 Corticorelin ovine triflutate [1] 75 💬
202 Longevity regulating pathway 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
203 Longevity regulating pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
204 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
205 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
206 Longevity regulating pathway - multiple species 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
207 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
208 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
209 MAPK signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
210 MAPK signaling pathway 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
211 MAPK signaling pathway 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
212 Melanoma 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
213 Melanoma 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
214 Melanoma 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
215 Metabolic pathways 💬
 [1] CYP11B1 💬 D00410 💬 Metyrapone [2] 75, 193 💬
216 Metabolic pathways 💬
 [1] CYP11B1 💬 D05019 💬 Metyrapone [2] 75, 193 💬
217 Metabolic pathways 💬
 [1] CYP11B2 💬 D11061 💬 Osilodrostat [1] 75 💬
218 Metabolic pathways 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
219 Metabolic pathways 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
220 MicroRNAs in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
221 MicroRNAs in cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
222 MicroRNAs in cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
223 MicroRNAs in cancer 💬
 [4] HDAC1, HDAC2, HDAC4, HDAC5 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
224 Mineral absorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
225 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
226 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
227 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
228 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
229 Neuroactive ligand-receptor interaction 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
230 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
231 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
232 Neuroactive ligand-receptor interaction 💬
 [2] CRHR1, CRHR2 💬 D03905 💬 Corticorelin [2] 75, 205 💬
233 Neuroactive ligand-receptor interaction 💬
 [2] CRHR1, CRHR2 💬 D03592 💬 Corticorelin ovine triflutate [1] 75 💬
234 Neuroactive ligand-receptor interaction 💬
 [2] DRD2, PRL 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
235 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
236 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
237 Neuroactive ligand-receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
238 Neuroactive ligand-receptor interaction 💬
 [1] GLP1R 💬 D06404 💬 Liraglutide [3]  6 , 75, 193 💬
239 Neuroactive ligand-receptor interaction 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [15]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
240 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00292 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
241 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00975 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
242 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01510 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
243 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01615 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
244 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01632 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
245 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01948 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
246 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02174 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
247 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02591 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
248 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02592 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
249 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00088 💬 Hydrocortisone [11]  6 , 41, 46, 53, 75, 78, 81, 83, 97, 98, 299 💬
250 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00585 💬 Mifepristone [1] 75 💬
251 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00472 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
252 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00980 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
253 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00981 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
254 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00982 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
255 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01239 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
256 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01998 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
257 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02156 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
258 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D03301 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
259 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D11336 💬 Relacorilant [1] 75 💬
260 Neuroactive ligand-receptor interaction 💬
 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 D10147 💬 Pasireotide [3] 67, 74, 75 💬
261 Neuroactive ligand-receptor interaction 💬
 [1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
262 Neuroactive ligand-receptor interaction 💬
 [1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
263 Neutrophil extracellular trap formation 💬
 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
264 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
265 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
266 Non-alcoholic fatty liver disease 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
267 Non-alcoholic fatty liver disease 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
268 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
269 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
270 Non-alcoholic fatty liver disease 💬
 [1] RXRA 💬 D03106 💬 Bexarotene [2] 13, 75 💬
271 Non-small cell lung cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
272 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
273 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
274 Non-small cell lung cancer 💬
 [1] RARB 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
275 Non-small cell lung cancer 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
276 Notch signaling pathway 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
277 Oocyte meiosis 💬
 [1] PGR 💬 D00585 💬 Mifepristone [1] 75 💬
278 Osteoclast differentiation 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
279 Osteoclast differentiation 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
280 Ovarian steroidogenesis 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
281 Oxytocin signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
282 Oxytocin signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
283 Oxytocin signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
284 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
285 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
286 Pancreatic cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
287 Pancreatic cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
288 Pancreatic cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
289 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
290 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
291 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
292 Parathyroid hormone synthesis, secretion and action 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
293 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
294 Parkinson disease 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
295 Pathways in cancer 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
296 Pathways in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
297 Pathways in cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
298 Pathways in cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
299 Pathways in cancer 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
300 Pathways in cancer 💬
 [3] PML, RARA, RARB 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
301 Pathways in cancer 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
302 Pathways in cancer 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
303 Pathways in cancer 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
304 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
305 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
306 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
307 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
308 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
309 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
310 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
311 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
312 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
313 PI3K-Akt signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
314 PI3K-Akt signaling pathway 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
315 PI3K-Akt signaling pathway 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
316 PI3K-Akt signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
317 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
318 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
319 PI3K-Akt signaling pathway 💬
 [1] PRL 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
320 PI3K-Akt signaling pathway 💬
 [1] RXRA 💬 D03106 💬 Bexarotene [2] 13, 75 💬
321 Platinum drug resistance 💬
 [1] ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
322 Platinum drug resistance 💬
 [1] ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
323 PPAR signaling pathway 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
324 PPAR signaling pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
325 PPAR signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
326 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 D00585 💬 Mifepristone [1] 75 💬
327 Prolactin signaling pathway 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
328 Prolactin signaling pathway 💬
 [1] PRL 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
329 Prostate cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
330 Prostate cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
331 Prostate cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
332 Protein digestion and absorption 💬
 [1] DPP4 💬 D08516 💬 Sitagliptin [4]  6 , 75, 233, 299 💬
333 Proteoglycans in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
334 Proteoglycans in cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
335 Proteoglycans in cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
336 Purine metabolism 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
337 Rap1 signaling pathway 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
338 Rap1 signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
339 Rap1 signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
340 Rap1 signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
341 Ras signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
342 Ras signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
343 Ras signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
344 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
345 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
346 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
347 Relaxin signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
348 Relaxin signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
349 Relaxin signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
350 Renin secretion 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
351 Renin-angiotensin system 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
352 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
353 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
354 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
355 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
356 Shigellosis 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
357 Shigellosis 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
358 Shigellosis 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
359 Small cell lung cancer 💬
 [1] RARB 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
360 Small cell lung cancer 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
361 Steroid hormone biosynthesis 💬
 [1] CYP11B1 💬 D00410 💬 Metyrapone [2] 75, 193 💬
362 Steroid hormone biosynthesis 💬
 [1] CYP11B1 💬 D05019 💬 Metyrapone [2] 75, 193 💬
363 Steroid hormone biosynthesis 💬
 [1] CYP11B2 💬 D11061 💬 Osilodrostat [1] 75 💬
364 Steroid hormone biosynthesis 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
365 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
366 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
367 Th17 cell differentiation 💬
 [1] RARA 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
368 Th17 cell differentiation 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
369 Thermogenesis 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
370 Thermogenesis 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
371 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
372 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
373 Thyroid cancer 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
374 Thyroid cancer 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
375 Thyroid cancer 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
376 Thyroid hormone signaling pathway 💬
 [3] HDAC1, HDAC2, HDAC3 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
377 Thyroid hormone signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
378 Tight junction 💬
 [1] ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
379 Tight junction 💬
 [1] ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
380 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
381 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
382 Transcriptional misregulation in cancer 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
383 Transcriptional misregulation in cancer 💬
 [2] PML, RARA 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
384 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
385 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
386 Transcriptional misregulation in cancer 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
387 Tuberculosis 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
388 Ubiquitin mediated proteolysis 💬
 [1] PML 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
389 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
390 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
391 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
392 Viral carcinogenesis 💬
 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬

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