Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Breast cancer 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
2 Breast cancer 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
3 Breast cancer 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
4 Breast cancer 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
5 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
6 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
7 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
8 Breast cancer 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
9 Breast cancer 💬
 [1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
10 Breast cancer 💬
 [1] PGR 💬 D08167 💬 Megestrol acetate [1] 76 💬
11 Breast cancer 💬
 [1] PGR 💬 D00066 💬 Progesterone [1] 76 💬
12 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
13 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
14 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
15 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
16 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
17 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
18 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
19 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
20 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
21 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
22 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
23 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
24 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
25 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
26 Chemical carcinogenesis - receptor activation 💬
 [1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
27 Chemical carcinogenesis - receptor activation 💬
 [1] PGR 💬 D08167 💬 Megestrol acetate [1] 76 💬
28 Chemical carcinogenesis - receptor activation 💬
 [1] PGR 💬 D00066 💬 Progesterone [1] 76 💬
29 Cytokine-cytokine receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
30 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
31 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
32 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
33 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
34 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
35 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
36 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
37 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
38 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
39 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
40 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
41 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
42 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
43 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
44 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
45 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
46 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
47 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
48 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
49 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
50 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
51 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
52 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
53 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
54 Estrogen signaling pathway 💬
 [1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
55 Estrogen signaling pathway 💬
 [1] PGR 💬 D08167 💬 Megestrol acetate [1] 76 💬
56 Estrogen signaling pathway 💬
 [1] PGR 💬 D00066 💬 Progesterone [1] 76 💬
57 GnRH secretion 💬
 [1] ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
58 GnRH secretion 💬
 [1] ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
59 GnRH secretion 💬
 [1] ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
60 GnRH secretion 💬
 [1] ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
61 GnRH secretion 💬
 [1] ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
62 GnRH secretion 💬
 [1] ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
63 GnRH secretion 💬
 [1] ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
64 GnRH secretion 💬
 [1] ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
65 GnRH signaling pathway 💬
 [1] GNRHR 💬 D00988 💬 Gonadorelin [1] 76 💬
66 GnRH signaling pathway 💬
 [1] GNRHR 💬 D03267 💬 Gonadorelin [1] 76 💬
67 GnRH signaling pathway 💬
 [1] GNRHR 💬 D04361 💬 Gonadorelin [1] 76 💬
68 GnRH signaling pathway 💬
 [1] GNRHR 💬 D08027 💬 Gonadorelin [1] 76 💬
69 GnRH signaling pathway 💬
 [1] GNRHR 💬 D02369 💬 Histrelin [1] 76 💬
70 GnRH signaling pathway 💬
 [1] GNRHR 💬 D00989 💬 Leuprolide [5]  1 ,  2 ,  3 , 51, 76 💬
71 GnRH signaling pathway 💬
 [1] GNRHR 💬 D06247 💬 Triptorelin [2] 49, 76 💬
72 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
73 JAK-STAT signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
74 Neuroactive ligand-receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
75 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D00988 💬 Gonadorelin [1] 76 💬
76 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D03267 💬 Gonadorelin [1] 76 💬
77 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D04361 💬 Gonadorelin [1] 76 💬
78 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D08027 💬 Gonadorelin [1] 76 💬
79 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D02369 💬 Histrelin [1] 76 💬
80 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D00989 💬 Leuprolide [5]  1 ,  2 ,  3 , 51, 76 💬
81 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D06247 💬 Triptorelin [2] 49, 76 💬
82 Oocyte meiosis 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
83 Oocyte meiosis 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
84 Oocyte meiosis 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
85 Oocyte meiosis 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
86 Oocyte meiosis 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
87 Oocyte meiosis 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
88 Oocyte meiosis 💬
 [1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
89 Oocyte meiosis 💬
 [1] PGR 💬 D08167 💬 Megestrol acetate [1] 76 💬
90 Oocyte meiosis 💬
 [1] PGR 💬 D00066 💬 Progesterone [1] 76 💬
91 Pathways in cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
92 Pathways in cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
93 Pathways in cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
94 Pathways in cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
95 Pathways in cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
96 Pathways in cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
97 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
98 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
99 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
100 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
101 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
102 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
103 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
104 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
105 PI3K-Akt signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
106 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
107 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 D08167 💬 Megestrol acetate [1] 76 💬
108 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 D00066 💬 Progesterone [1] 76 💬
109 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
110 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
111 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
112 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
113 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
114 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
115 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
116 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
117 Prostate cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
118 Prostate cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
119 Prostate cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
120 Prostate cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
121 Prostate cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
122 Prostate cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
123 Proteoglycans in cancer 💬
 [1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
124 Proteoglycans in cancer 💬
 [1] ESR1 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
125 Proteoglycans in cancer 💬
 [1] ESR1 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
126 Proteoglycans in cancer 💬
 [1] ESR1 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
127 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
128 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
129 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
130 Proteoglycans in cancer 💬
 [1] ESR1 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
131 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
132 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
133 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
134 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
135 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
136 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
137 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
138 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬

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