Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Prolactin signaling pathway 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
2 Prolactin signaling pathway 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
3 Prolactin signaling pathway 💬
 [1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
4 Prolactin signaling pathway 💬
 [1] ESR1 💬 D00554 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
5 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D00962 💬 Clomifene [1] 74 💬
6 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D07726 💬 Clomifene [1] 74 💬
7 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
8 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
9 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
10 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
11 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
12 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
13 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
14 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
15 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
16 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
17 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol valerate [1] 65 💬
18 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D00185 💬 Estriol [2] 13, 227 💬
19 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01986 💬 Estriol [2] 13, 227 💬
20 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
21 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D00575 💬 Mestranol [2] 46, 49 💬
22 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
23 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D02217 💬 Raloxifene [1] 46 💬
24 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D08465 💬 Raloxifene [1] 46 💬
25 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D00966 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
26 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D08559 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
27 Prolactin signaling pathway 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
28 Prolactin signaling pathway 💬
 [1] JAK2 💬 D10653 💬 Peficitinib [1] 46 💬
29 Prolactin signaling pathway 💬
 [1] JAK2 💬 D09959 💬 Ruxolitinib [1] 228 💬
30 Prolactin signaling pathway 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
31 Prolactin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
32 Prolactin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
33 Prolactin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
34 Prolactin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
35 Prolactin signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
36 Prolactin signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
37 Prolactin signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
38 Prolactin signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
39 Prolactin signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
40 Prolactin signaling pathway 💬
 [1] PRL 💬 D00780 💬 Bromocriptine [2]  6 , 74 💬
41 Prolactin signaling pathway 💬
 [1] PRL 💬 D03165 💬 Bromocriptine [2]  6 , 74 💬
42 Prolactin signaling pathway 💬
 [1] PRL 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
43 Prolactin signaling pathway 💬
 [1] PRL 💬 D01348 💬 Terguride [2] 51, 86 💬
44 Prolactin signaling pathway 💬
 [1] RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
45 Prolactin signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
46 Prolactin signaling pathway 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
47 Prolactin signaling pathway 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
48 Prolactin signaling pathway 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
49 Prolactin signaling pathway 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
50 Prolactin signaling pathway 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
51 Prolactin signaling pathway 💬
 [1] TNFSF11 💬 D03684 💬 Denosumab [7] 46, 50, 93, 95, 96, 274, 299 💬