Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Hepatitis B 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
2 Hepatitis B 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
3 Hepatitis B 💬
 [2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
4 Hepatitis B 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
5 Hepatitis B 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
6 Hepatitis B 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
7 Hepatitis B 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
8 Hepatitis B 💬
 [1] IFNAR1 💬 D11082 💬 Anifrolumab [2] 46, 49 💬
9 Hepatitis B 💬
 [1] IFNAR1 💬 D03305 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
10 Hepatitis B 💬
 [1] IFNAR1 💬 D00745 💬 Interferon alfa-2a [1] 56 💬
11 Hepatitis B 💬
 [1] IFNAR1 💬 D02745 💬 Interferon alfa-2b [2] 25, 34 💬
12 Hepatitis B 💬
 [1] IFNAR1 💬 D04554 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
13 Hepatitis B 💬
 [1] IFNAR1 💬 D00746 💬 Interferon beta-1b [1] 13 💬
14 Hepatitis B 💬
 [1] IFNAR1 💬 D10483 💬 Peginterferon beta-1a [1] 13 💬
15 Hepatitis B 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
16 Hepatitis B 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
17 Hepatitis B 💬
 [2] IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
18 Hepatitis B 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
19 Hepatitis B 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
20 Hepatitis B 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
21 Hepatitis B 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
22 Hepatitis B 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
23 Hepatitis B 💬
 [2] JAK1, JAK2 💬 D09959 💬 Ruxolitinib [1] 228 💬
24 Hepatitis B 💬
 [3] JAK1, JAK2, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
25 Hepatitis B 💬
 [4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
26 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
27 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
28 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
29 Hepatitis B 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
30 Hepatitis B 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
31 Hepatitis B 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
32 Hepatitis B 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
33 Hepatitis B 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
34 Hepatitis B 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
35 Hepatitis B 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
36 Hepatitis B 💬
 [1] SLC10A1 💬 D10951 💬 Maralixibat [3] 296, 297, 338 💬
37 Hepatitis B 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
38 Hepatitis B 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
39 Hepatitis B 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
40 Hepatitis B 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
41 Hepatitis B 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬
42 Hepatitis B 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
43 Hepatitis B 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
44 Hepatitis B 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
45 Hepatitis B 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
46 Hepatitis B 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
47 Hepatitis B 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
48 Hepatitis B 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
49 Hepatitis B 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
50 Hepatitis B 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
51 Hepatitis B 💬
 [1] TYK2 💬 D11817 💬 Deucravacitinib [2] 96, 97 💬