Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Oxygen
(Synonym: CARBON DIOXIDE/OXYGEN 5/95)		[1] Oxygen (Synonym: Carbon Dioxide Oxygen Mixtures)[3] Medical air; Nitrogen; Oxygen; --[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
2 Carbon dioxide [1] Carbon dioxide[1] Carbon dioxide; --[2] 97, 158
3 Urea
(Synonym: Carbamide)		[1] Urea (Synonym: Gehwol med Callus)[1] Urea; --[2] 72, 251
4 Cobamamide
(Synonym: Calomide (TN))		[1] Cobamamide (Synonym: Acti-folic + Dibencozide Caplets)[1] Cobamamide; --[1] 299
5 Iodine
(Synonym: Cadex (TN))		[1] Iodine (Synonym: Bal-Care DHA Essential)[2] Iodine; Iodo; --[2] 28, 46
6 Calcifediol [1] Calcifediol[2] 25-Hydroxyvitamin D3; CALCIFEDIOL; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 113, 299
7 Ibuprofen
(Synonym: CALDOLOR)		[1] Ibuprofen (Synonym: Care One Ibuprofen Cold and Sinus)[2] IBUPROFEN; IBUPROFEN 200MG; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
8 Calcitriol [1] Calcitriol[1] Calcitriol; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326
9 Hymecromone
(Synonym: Cantabiline (TN))		[1] Hymecromone[1] Hymecromone; --[1] 94
10 Alprostadil
(Synonym: Caverject (TN))		[1] Alprostadil (Synonym: Caverject)[1] Alprostadil; [1] PTGER1 💬[4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬[2] 51, 70
11 Norethindrone
(Synonym: Camila (TN))		[1] Norethisterone (Synonym: Camila)[3] Norethindrone; Ortho-novum; Ortho-Novum 777; [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[4] 13, 46, 49, 299
12 Ergocalciferol
(Synonym: Calciferol (TN))		[1] Ergocalciferol (Synonym: Cal/mag 2)[3] Ergocalciferol; Vitamin D; Vitamin D2; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299
13 Aztreonam
(Synonym: CAYSTON)		[1] Aztreonam (Synonym: Cayston)[2] AZTREONAM; Cayston; --[2] 228, 299
14 Capsaicin [1] Capsaicin[2] Capsaicin; Qutenza; [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226
15 Captopril [1] Captopril[1] Captopril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[8] 6, 17, 46, 86, 96, 97, 107, 271
16 Carbamazepine [1] Carbamazepine[1] Carbamazepine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 6, 13, 231
17 Carmustine [1] Carmustine[1] Carmustine; --[5] 11, 13, 14, 28, 60
18 Carvedilol [1] Carvedilol[1] Carvedilol; [5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		[13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 86, 113, 210
19 Clonidine
(Synonym: Catarpres-TTS (TN))		[1] Clonidine (Synonym: Catapres-TTS-1)[4] Clonidin; Clonidina; Clonidine; Clonidine hydrochloride; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78
20 Mesalamine
(Synonym: Canasa (TN))		[1] Mesalazine (Synonym: Canasa)[10] 5-Aminosalicylic acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; MESALAZINE; Mesalazinum; MEZAVANT; Pentasa; Salofalk; --[5] 46, 96, 97, 98, 164
21 Spironolactone
(Synonym: CAROSPIR)		[1] Spironolactone (Synonym: CaroSpir)[1] Spironolactone; [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[8] 46, 58, 67, 86, 113, 210, 218, 225
22 Sucralfate
(Synonym: Carafate (TN))		[1] Sucralfate (Synonym: Carafate)[1] Sucralfate; --[1] 98
23 Candesartan [1] Candesartan[1] CANDESARTAN; [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 58, 67
24 Caffeine [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
25 Carbidopa [1] Carbidopa[8] Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo; [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201
26 Candesartan cilexetil [1] Candesartan cilexetil[1] CANDESARTAN; [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67
27 Lithium carbonate [1] Lithium carbonate[2] Lithium; Lithium Carbonate; --[5] 2, 13, 17, 18, 127
28 Calcium carbonate [1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium carbonate; --[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
29 Calcium citrate [1] Calcium citrate[1] Calcium citrate; --[3] 46, 84, 235
30 Calcium gluconate [1] Calcium gluconate[1] Calcium gluconate; --[3] 214, 215, 235
31 Calcium lactate [1] Calcium lactate[1] Calcium lactate; --[1] 235
32 Cabergoline [1] Cabergoline[3] CABERGOLINA; CABERGOLINE; DOSTINEX; [2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75
33 Calcipotriene [1] Calcipotriol[2] Calcipotriene; CALCIPOTRIOL; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 36, 51
34 Carboplatin [1] Carboplatin[2] Carboplatin; CBDCA; --[4] 28, 34, 60, 85
35 Caffeine hydrate [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
36 Fluocinolone acetonide
(Synonym: CAPEX)		[1] Fluocinolone acetonide (Synonym: Capex)[2] Fluocinolone Acetonide; Iluvien; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 90
37 Potassium carbonate [1] Potassium carbonate[0] --[3] 6, 96, 291
38 Levocarnitine
(Synonym: L-Carnitine)		[1] Levocarnitine (Synonym: Carnitor SF)[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
39 Calcium lactate hydrate [1] Calcium lactate[1] Calcium lactate; --[1] 235
40 Pregabalin
(Synonym: PREGABALIN CAPSULES, CV)		[1] Pregabalin (Synonym: Pregabalin Capsules)[2] Lyrica; Pregabalin; [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
41 Alemtuzumab
(Synonym: Campath (TN))		[1] Alemtuzumab (Synonym: Campath)[4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH; [1] CD52 💬-[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
42 beta Carotene [1] Beta carotene[3] Beta carotene; Beta-Carotene; BETACAROTENE; --[2] 13, 96
43 Calfactant [1] Calfactant[1] Calfactant; --[1] 299
44 Calusterone [1] Calusterone[0] [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 2
45 Carbaspirin calcium [1] Carbaspirin calcium[1] Carbasalate calcium; --[1] 46
46 Erythrityl tetranitrate
(Synonym: Cardilate (TN))		[1] Erythrityl tetranitrate[0] [2] NPR1,
NPR2 💬		[10] Aldosterone synthesis and secretion, Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 46
47 Lactobacillus casei [1] Lactobacillus casei[2] Fusion; Lactobacillus casei; --[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296
48 Carisbamate [1] Carisbamate[1] Carisbamate; --[1] 144
49 Green tea leaf
(Synonym: Cameliae sinesis folium)		[1] Green tea leaf (Synonym: Camelliae Sinensis Non Fermentatum Folium)[4] Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract; --[4] 6, 17, 28, 46
50 Carglumic acid [1] Carglumic acid[3] Carbaglu; Carglumic Acid; N-Carbamylglutamate; [1] CPS1 💬[6] Alanine, aspartate and glutamate metabolism, Arginine biosynthesis, Biosynthesis of amino acids, Carbon metabolism, Metabolic pathways, Nitrogen metabolism 💬[3] 245, 246, 251
51 Caspofungin [1] Caspofungin[2] Caspofungin; CASPOFUNGIN ACETATE; --[1] 60
52 Ceftazidime
(Synonym: CAZ)		[1] Ceftazidime[3] Ceftazidim; Ceftazidima; CEFTAZIDIME; --[1] 299
53 Choline
(Synonym: Choline cation)		[1] Choline (Synonym: Card-floe II Tab)[1] Choline; --[4] 93, 171, 193, 299
54 Doxazosin
(Synonym: Cardura XL (TN))		[1] Doxazosin (Synonym: Cardura-1 Tab 1mg)[2] CARDURA; Doxazosin; [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 57, 67
55 Folinic acid calcium salt pentahydrate [1] Leucovorin (Synonym: Leucovorin Calcium Injection USP)[2] Folinic acid; Leucovorin; --[4] 19, 46, 107, 320
56 Hyaluronic acid
(Synonym: Captique (TN))		[1] Hyaluronic acid[2] Hyaluronate; Hyaluronic acid; --[6] 46, 53, 70, 97, 226, 231
57 Nicardipine
(Synonym: Cardene (TN))		[1] Nicardipine (Synonym: Cardene Cap 30mg)[1] Nicardipine; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 70, 86
58 Carfilzomib [1] Carfilzomib[1] Carfilzomib; [1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[1] 28
59 Ferric carboxymaltose [1] Ferric carboxymaltose[1] Ferric carboxymaltose; --[4] 86, 96, 97, 299
60 Canakinumab [1] Canakinumab[2] Canakinumab; ILARIS; [1] IL1B 💬[44] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
61 Carbon monoxide [1] Carbon monoxide[1] Carbon monoxide; --[4] 13, 53, 85, 86
62 Cariprazine [1] Cariprazine[1] Reagila; [3] DRD2,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 21
63 Cabozantinib [1] Cabozantinib[1] Cabozantinib; [3] AXL,
KDR,
MET 💬		[25] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, EGFR tyrosine kinase inhibitor resistance, Epithelial cell signaling in Helicobacter pylori infection, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, Hepatocellular carcinoma, MAPK signaling pathway, Malaria, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Renal cell carcinoma, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 34
64 Catridecacog [1] Catridecacog[1] Catridecacog; --[2] 97, 288
65 Cabotegravir [1] Cabotegravir[1] Cabotegravir; --[1] 256
66 Calcium carbonate [1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium Carbonate; --[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
67 Acalabrutinib
(Synonym: Calquence (TN))		[1] Acalabrutinib (Synonym: Calquence)[1] Acalabrutinib; [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 46, 61
68 Cannabidiol [1] Cannabidiol[4] CANNABIDIOL; Epidiolex; Epidyolex; SATIVEX; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
69 Cavosonstat [1] Cavosonstat[1] Cavosonstat; --[1] 299
70 Caplacizumab [1] Caplacizumab[2] CABLIVI; CAPLACIZUMAB; [1] VWF 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬[1] 64
71 Casimersen [1] Casimersen[1] CASIMERSEN; [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
72 Mavacamten
(Synonym: Camzyos (TN))		[1] Mavacamten (Synonym: Camzyos)[1] MAVACAMTEN; [1] MYH7 💬[7] Adrenergic signaling in cardiomyocytes, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Thyroid hormone signaling pathway, Viral myocarditis, cGMP-PKG signaling pathway 💬[1] 58