Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
2 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Alendronic acid 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
3 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Pamidronic acid 💬 Pamidronic acid [3] 270, 271, 274 💬
4 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Risedronic acid 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
5 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
6 FNTA 💬 [1] Terpenoid backbone biosynthesis Tipifarnib 💬 Tipifarnib [1] 34 💬
7 FNTA 💬 [1] Terpenoid backbone biosynthesis Lonafarnib 💬 Lonafarnib [2] 113, 333 💬
8 FNTB 💬 [1] Terpenoid backbone biosynthesis Tipifarnib 💬 Tipifarnib [1] 34 💬
9 FNTB 💬 [1] Terpenoid backbone biosynthesis Lonafarnib 💬 Lonafarnib [2] 113, 333 💬
10 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Lovastatin 💬 Lovastatin [11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
11 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Simvastatin 💬 Simvastatin [21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
12 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Atorvastatin 💬 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
13 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Fluvastatin 💬 Fluvastatin [3] 79, 218, 222 💬
14 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Pravastatin 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
15 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Rosuvastatin 💬 Rosuvastatin [11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬