Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 FDPS [1] Terpenoid backbone biosynthesis D01968 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
2 FDPS [1] Terpenoid backbone biosynthesis D07119 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299
3 FDPS [1] Terpenoid backbone biosynthesis D07281 Pamidronic acid [3] 270, 271, 274
4 FDPS [1] Terpenoid backbone biosynthesis D08484 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274
5 FDPS [1] Terpenoid backbone biosynthesis D08689 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
6 FNTA [1] Terpenoid backbone biosynthesis D03720 Tipifarnib [1] 34
7 FNTA [1] Terpenoid backbone biosynthesis D04768 Lonafarnib [2] 113, 333
8 FNTB [1] Terpenoid backbone biosynthesis D03720 Tipifarnib [1] 34
9 FNTB [1] Terpenoid backbone biosynthesis D04768 Lonafarnib [2] 113, 333
10 HMGCR [1] Terpenoid backbone biosynthesis D00359 Lovastatin [11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
11 HMGCR [1] Terpenoid backbone biosynthesis D00434 Simvastatin [21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
12 HMGCR [1] Terpenoid backbone biosynthesis D07474 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
13 HMGCR [1] Terpenoid backbone biosynthesis D07983 Fluvastatin [3] 79, 218, 222
14 HMGCR [1] Terpenoid backbone biosynthesis D08410 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333
15 HMGCR [1] Terpenoid backbone biosynthesis D08492 Rosuvastatin [11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299