Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
3 Alanine, aspartate and glutamate metabolism 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
4 Alcoholism 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
5 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
6 Alcoholism 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
7 Alcoholism 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
8 Aldosterone synthesis and secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
9 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
10 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
11 Alzheimer disease 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
12 Alzheimer disease 💬
 [1] MAPT 💬 Gosuranemab 💬 Gosuranemab [1]  5  💬
13 Alzheimer disease 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
14 Alzheimer disease 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
15 Amphetamine addiction 💬
 [1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
16 Amphetamine addiction 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
17 Amphetamine addiction 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
18 Amphetamine addiction 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
19 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
20 Amyotrophic lateral sclerosis 💬
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
21 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
22 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
23 Arginine and proline metabolism 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
24 Arginine and proline metabolism 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
25 Axon guidance 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
26 beta-Alanine metabolism 💬
 [3] ABAT, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
27 Breast cancer 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
28 Butanoate metabolism 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
29 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
30 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
31 Calcium signaling pathway 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
32 Calcium signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
33 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
34 Calcium signaling pathway 💬
 [1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
35 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
36 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
37 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
38 cAMP signaling pathway 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
39 cAMP signaling pathway 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
40 cAMP signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
41 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
42 cGMP-PKG signaling pathway 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
43 cGMP-PKG signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
44 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
45 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
46 Chemical carcinogenesis - receptor activation 💬
 [3] ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
47 Chemokine signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
48 Cholinergic synapse 💬
 [1] ACHE 💬 Donepezil 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
49 Cholinergic synapse 💬
 [1] ACHE 💬 Rivastigmine 💬 Rivastigmine [3]  5 ,  6 , 13 💬
50 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
51 Circadian entrainment 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
52 Circadian entrainment 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
53 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
54 Cocaine addiction 💬
 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
55 Cocaine addiction 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
56 Cocaine addiction 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
57 Cortisol synthesis and secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
58 Cushing syndrome 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
59 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
60 Dopaminergic synapse 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
61 Dopaminergic synapse 💬
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
62 Dopaminergic synapse 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
63 Dopaminergic synapse 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
64 Drug metabolism - cytochrome P450 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
65 Drug metabolism - cytochrome P450 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
66 Focal adhesion 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
67 GABAergic synapse 💬
 [3] ABAT, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
68 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
69 Gap junction 💬
 [1] ADRB1 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
70 Gap junction 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
71 Gastric acid secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
72 Glutamatergic synapse 💬
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
73 Glycerophospholipid metabolism 💬
 [1] ACHE 💬 Donepezil 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
74 Glycerophospholipid metabolism 💬
 [1] ACHE 💬 Rivastigmine 💬 Rivastigmine [3]  5 ,  6 , 13 💬
75 Glycine, serine and threonine metabolism 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
76 Glycine, serine and threonine metabolism 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
77 GnRH secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
78 Hematopoietic cell lineage 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
79 Histidine metabolism 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
80 Histidine metabolism 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
81 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
82 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
83 Human cytomegalovirus infection 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
84 Human papillomavirus infection 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
85 Human papillomavirus infection 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
86 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
87 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
88 Huntington disease 💬
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
89 IL-17 signaling pathway 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
90 IL-17 signaling pathway 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
91 Influenza A 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
92 Influenza A 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
93 Insulin secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
94 Insulin secretion 💬
 [1] SNAP25 💬 Botulinum toxin type A 💬 Botulinum toxin type A [14]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
95 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
96 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
97 Leishmaniasis 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
98 Leishmaniasis 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
99 Leukocyte transendothelial migration 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
100 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
101 Long-term depression 💬
 [3] GRIA1, GRIA2, GRIA3 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
102 Long-term potentiation 💬
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
103 MAPK signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
104 MAPK signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
105 MAPK signaling pathway 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
106 MAPK signaling pathway 💬
 [1] MAPT 💬 Gosuranemab 💬 Gosuranemab [1]  5  💬
107 Melanogenesis 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
108 Metabolic pathways 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
109 Metabolic pathways 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
110 Metabolic pathways 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
111 Metabolic pathways 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
112 Metabolic pathways 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
113 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
114 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
115 MicroRNAs in cancer 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
116 MicroRNAs in cancer 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
117 MicroRNAs in cancer 💬
 [1] ROCK1 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
118 Morphine addiction 💬
 [1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
119 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
120 Neuroactive ligand-receptor interaction 💬
 [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
121 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
122 Neuroactive ligand-receptor interaction 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
123 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
124 Neuroactive ligand-receptor interaction 💬
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
125 Neuroactive ligand-receptor interaction 💬
 [2] HCRTR1, HCRTR2 💬 Suvorexant 💬 Suvorexant [3]  5 ,  6 , 13 💬
126 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
127 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
128 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
129 Nicotine addiction 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
130 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
131 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
132 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
133 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
134 Oxytocin signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
135 Pancreatic secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
136 Parkinson disease 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
137 Parkinson disease 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
138 Parkinson disease 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
139 Parkinson disease 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
140 Parkinson disease 💬
 [1] MAPT 💬 Gosuranemab 💬 Gosuranemab [1]  5  💬
141 Pathogenic Escherichia coli infection 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
142 Pathways in cancer 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
143 Pathways in cancer 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
144 Pathways in cancer 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
145 Pathways in cancer 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
146 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
147 Pathways of neurodegeneration - multiple diseases 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
148 Pathways of neurodegeneration - multiple diseases 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
149 Pathways of neurodegeneration - multiple diseases 💬
 [1] MAPT 💬 Gosuranemab 💬 Gosuranemab [1]  5  💬
150 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
151 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
152 Phenylalanine metabolism 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
153 Phenylalanine metabolism 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
154 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
155 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
156 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
157 Platelet activation 💬
 [1] PTGS1 💬 Salsalate 💬 Salsalate [1]  5  💬
158 Platelet activation 💬
 [1] PTGS1 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
159 Platelet activation 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
160 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
161 Propanoate metabolism 💬
 [1] ABAT 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
162 Proteoglycans in cancer 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
163 Rap1 signaling pathway 💬
 [1] DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
164 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
165 Rap1 signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
166 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
167 Ras signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
168 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
169 Regulation of actin cytoskeleton 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
170 Regulation of lipolysis in adipocytes 💬
 [3] ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
171 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
172 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
173 Renin secretion 💬
 [3] ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
174 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
175 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
176 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
177 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
178 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
179 Salivary secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
180 Salmonella infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
181 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
182 Serotonergic synapse 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
183 Serotonergic synapse 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
184 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
185 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
186 Shigellosis 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
187 Small cell lung cancer 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
188 Small cell lung cancer 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
189 Sphingolipid signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
190 Spinocerebellar ataxia 💬
 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
191 Synaptic vesicle cycle 💬
 [1] SNAP25 💬 Botulinum toxin type A 💬 Botulinum toxin type A [14]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
192 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
193 Taste transduction 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
194 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
195 Taurine and hypotaurine metabolism 💬
 [2] GAD1, GAD2 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
196 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
197 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
198 TGF-beta signaling pathway 💬
 [1] ROCK1 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
199 Thermogenesis 💬
 [1] ADRB3 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
200 Tight junction 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
201 TNF signaling pathway 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
202 TNF signaling pathway 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
203 Transcriptional misregulation in cancer 💬
 [1] GRIA3 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
204 Tryptophan metabolism 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
205 Tryptophan metabolism 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
206 Type I diabetes mellitus 💬
 [2] GAD1, GAD2 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
207 Type II diabetes mellitus 💬
 [1] CACNA1G 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
208 Tyrosine metabolism 💬
 [1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
209 Tyrosine metabolism 💬
 [1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
210 Valine, leucine and isoleucine degradation 💬
 [1] ABAT 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
211 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
212 Vascular smooth muscle contraction 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
213 VEGF signaling pathway 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
214 VEGF signaling pathway 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
215 Wnt signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
216 Yersinia infection 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬

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