Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir
(Synonym: Apo-abacavir)		[4] Abacavir; Abacavir sulfate; Triumeq; Ziagen[2] D00891 ,
D07057 		--[4] 2, 135, 265, 325
2 Abiraterone
(Synonym: Apo-abiraterone)		[3] Abiraterone; Abiraterone acetate; ZYTIGA---[2] 75, 81
3 Acetaminophen
(Synonym: Medique Apap)		[5] Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
4 Acetylsalicylic acid
(Synonym: Biovanta Trip Action Green Apple and Honey)		[2] Acetylsalicylic Acid; Aspirin[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
5 Acyclovir
(Synonym: Apo-acyclovir)		[3] ACICLOVIR; Acycloguanosine; Acyclovir[1] D00222 --[5] 13, 28, 46, 53, 60
6 Adenosine
(Synonym: Applicell Essential Toner)		[2] Adenosine; Ginseng[1] D00045 [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65
7 Alendronic acid
(Synonym: Apo-alendronate/vitamin D3)		[3] Alendronate; Alendronate sodium; ALENDRONIC ACID[2] D00939 ,
D07119 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
8 Alfuzosin
(Synonym: Apo-alfuzosin)		[1] Alfuzosin[2] D01692 ,
D07124 		[1] ADRA1A 💬[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13
9 Allopurinol
(Synonym: Apo-allopurinol)		[2] Allopurinol; ALLOPURINOL SODIUM[1] D00224 [1] XDH 💬[5] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism 💬[6] 6, 46, 57, 66, 96, 97
10 Alprazolam
(Synonym: Apo-alpraz Ts)		[1] Alprazolam[1] D00225 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75
11 Ambrisentan
(Synonym: Apo-ambrisentan)		[3] Ambrisentan; Letairis; VOLIBRIS[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 51, 84, 85, 86, 88, 210, 211
12 Aminopterin
(Synonym: APGA)		[1] Aminopterin---[1] 46
13 Amiodarone
(Synonym: Apo-amiodarone Tablets)		[1] Amiodarone[2] D00636 ,
D02910 		[16] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[32] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 28, 127
14 Amitriptyline
(Synonym: Apo Peram Tab 3-15)		[3] Amitriptylin; Amitriptyline; Amitriptyline hydrochloride[2] D00809 ,
D07448 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299
15 Amlodipine
(Synonym: Apo-amlodipine-atorvastatin)		[1] Amlodipine[3] D00615 ,
D02914 ,
D07450 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
16 Amoxicillin
(Synonym: Apo-amoxicillin-clavulanate)		[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin[3] D00229 ,
D02925 ,
D07452 		--[9] 6, 19, 46, 63, 84, 96, 97, 222, 299
17 Ampicillin
(Synonym: Apo Ampi Capsules 500mg)		[1] ABPC[3] D00204 ,
D01251 ,
D02119 		--[5] 2, 6, 13, 84, 299
18 Anastrozole
(Synonym: Apo-anastrozole)		[2] ANASTROZOLE; Arimidex[1] D00960 [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193
19 Apabetalone [1] Apabetalone[1] D11131 (Name: Apabetalone)[4] BRD2,
BRD3,
BRD4,
BRDT 💬		-[1] 86
20 Apadamtase alfa [1] Apadamtase alfa---[1] 64
21 Apigenin [1] Apigenin---[1] 97
22 Apitegromab [1] Apitegromab[1] D11797 (Name: Apitegromab)[1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 3
23 Apixaban [2] Apixaban; Eliquis[1] D03213 (Name: Apixaban)[1] F10 💬[1] Complement and coagulation cascades 💬[3] 96, 97, 222
24 Aplindore [1] Aplindore---[1] 6
25 Apomorphine [3] APOKYN; Apomorfina; Apomorphine[2] D02004 (Name: Apomorphine hydrochloride),
D07460 (Name: Apomorphine)		[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7
26 Apple [1] Apple---[1] 70
27 Apraclonidine [1] Apraclonidine[2] D01008 (Name: Apraclonidine hydrochloride),
D07461 (Name: Apraclonidine)		[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11
28 Apratastat [1] Apratastat[1] D08859 (Name: Apratastat)[2] ADAM17,
MMP13 💬		[7] Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬[1] 46
29 Apremilast [2] APREMILAST; Otezla[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271
30 Aprotinin [1] Aprotinin[1] D02971 (Name: Aprotinin)--[1] 28
31 Aripiprazole
(Synonym: Apo-aripiprazole)		[1] Aripiprazole[1] D01164 [4] DRD2,
DRD3,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206
32 Ascorbic acid
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		[4] Acidum ascorbicum; ASCORBIC ACID; Iron; Vitamin C[1] D00018 --[8] 10, 97, 192, 206, 210, 211, 212, 298
33 Atazanavir
(Synonym: Apo-atazanavir)		[2] Atazanavir; Reyataz[2] D01276 ,
D07471 		--[1] 265
34 Atenolol
(Synonym: Apo-atenol Tab 100mg)		[1] ATENOLOL[1] D00235 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167
35 Atomoxetine
(Synonym: Apo-atomoxetine)		[2] Atomoxetine; Strattera[2] D02574 ,
D07473 		[1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
36 Atorvastatin
(Synonym: Apo-amlodipine-atorvastatin)		[3] Atorvastatin; Atorvastatin Calcium; Lipitor[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
37 Atovaquone
(Synonym: Apo-atovaquone)		[1] ATOVAQUONE[1] D00236 --[1] 61
38 Azathioprine
(Synonym: Apo-azathioprine)		[3] AZATHIOPRINE; AZATIOPRINA; Imuran[2] D00238 ,
D03033 		--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
39 Azithromycin
(Synonym: Apo-azithromycin Z)		[5] AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX[3] D02134 ,
D06390 ,
D07486 		--[6] 13, 84, 85, 96, 228, 299
40 Baclofen
(Synonym: Apo-baclofen)		[2] Baclofen; Kemstro[1] D00241 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[7] 2, 10, 13, 18, 65, 149, 206
41 Beclomethasone dipropionate
(Synonym: Apo-beclomethasone Nasal Spray)		[2] BECLOMETASONE DIPROPIONATE; Beclomethasone dipropionate[2] D00689 ,
D07495 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 85, 97, 98
42 Bisacodyl
(Synonym: Apo-bisacodyl Sup 10mg)		[1] Bisacodyl[1] D00245 --[1] 13
43 Bisoprolol
(Synonym: Apo-bisoprolol)		[2] BISOPROLOL; Bisoprolol Fumarate[2] D00634 ,
D02342 		[1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 67, 86, 113
44 Bosentan
(Synonym: Apo-bosentan)		[2] Bosentan; Tracleer[2] D01227 ,
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
45 Brimonidine
(Synonym: Apo-brimonidine)		[2] Brimonidine; Brimonidine Tartrate[2] D02076 ,
D07540 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 13, 90
46 Bupropion
(Synonym: Appbutamone-D)		[2] Bupropion; Bupropion Hydrochloride[3] D00817 ,
D07591 ,
D07938 (Name: Aplenzin (TN))		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
47 Buspirone
(Synonym: Apo-buspirone)		[2] Buspirone; Buspirone Hydrochloride[2] D00702 ,
D07593 		[2] DRD2,
HTR1A 💬		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[3] 6, 51, 179
48 Cabergoline
(Synonym: Apo-cabergoline)		[3] CABERGOLINA; Cabergoline; DOSTINEX[1] D00987 [2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75
49 Caffeine
(Synonym: Apo-acetaco #1)		[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
50 Calcium carbonate
(Synonym: Apatite Professional)		[3] Calcio carbonato; Calcium; Calcium Carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
51 Candesartan cilexetil
(Synonym: Apo-candesartan/hctz)		[1] CANDESARTAN[2] D00522 ,
D00626 		[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67
52 Capecitabine
(Synonym: Apo-capecitabine)		[1] Capecitabine[1] D01223 [1] TYMS 💬[4] Antifolate resistance, Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism 💬[1] 94
53 Capsaicin
(Synonym: Capzasin No Mess Applicator)		[2] Capsaicin; Qutenza[1] D00250 [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226
54 Captopril
(Synonym: Apo-capto Tab 100mg)		[1] Captopril[1] D00251 (Name: Apopril (TN))[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[8] 6, 17, 46, 86, 96, 97, 107, 271
55 Carbamazepine
(Synonym: Apo-carbamazepine)		[1] Carbamazepine[1] D00252 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[2] 13, 231
56 Carbidopa
(Synonym: Apo-levocarb-tab 25mg/100mg)		[7] Carbidopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] D00558 [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[9] 2, 4, 6, 13, 17, 90, 140, 164, 201
57 Carvedilol
(Synonym: Apo-carvedilol)		[1] Carvedilol[2] D00255 ,
D03415 		[5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		[13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 57, 86, 113, 210
58 Cefadroxil
(Synonym: Apo-cefadroxil)		[0] [2] D00257 ,
D02353 		--[2] 222, 240
59 Cefepime
(Synonym: Apo-cefepime)		[1] Cefepime[1] D02376 --[2] 60, 299
60 Cefuroxime
(Synonym: Apo-cefuroxime)		[2] Cefuroxim; CEFUROXIME[4] D00262 ,
D00914 ,
D00915 ,
D03431 		--[2] 97, 299
61 Celecoxib
(Synonym: Apo-celecoxib)		[2] Celebrex; Celecoxib[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
62 Cephalexin
(Synonym: Apo-cephalex)		[2] CEFALEXIN; Cephalexin[2] D00263 ,
D00906 		--[1] 299
63 Cetirizine
(Synonym: Apo-cetirizine)		[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[2] D00664 ,
D07662 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300
64 Chlordiazepoxide
(Synonym: Not applicable)		[0] [2] D00267 ,
D00693 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 46
65 Chlorhexidine
(Synonym: Chlorhexidine Gluconate Applicator)		[2] Chlorhexidine; Chlorhexidine Gluconate[4] D00858 ,
D01345 ,
D03463 ,
D07668 		--[2] 86, 299
66 Chlorpheniramine
(Synonym: Aphedrid Cold and Allergy)		[1] Clorfenamina[4] D00665 ,
D00668 ,
D07398 ,
D07803 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
67 Chlorpromazine
(Synonym: Apo Chlorpromazine)		[2] Chlorpromazine; Chlorpromazine Hydrochloride[4] D00270 ,
D00789 ,
D03274 ,
D04034 		[13] ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		[22] Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 254
68 Cholecalciferol
(Synonym: Apcal)		[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[25] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
69 Ciclesonide
(Synonym: Apo-ciclesonide)		[1] Ciclesonide[1] D01703 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 84
70 Cilazapril
(Synonym: Apo-cilazapril)		[1] Cilazapril[2] D01069 ,
D07699 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 66
71 Cimetidine
(Synonym: Apo-cimetidine Oral Solution)		[1] Cimetidine[2] D00295 ,
D03503 		[1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254
72 Cinacalcet
(Synonym: Apo-cinacalcet)		[1] Cinacalcet[2] D03504 ,
D03505 		[1] CASR 💬[2] NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬[2] 85, 238
73 Ciprofloxacin
(Synonym: Apo-ciproflox)		[2] Ciprofloxacin; Ciprofloxacin hydrochloride[2] D00186 ,
D02216 		--[5] 2, 60, 96, 97, 299
74 Citalopram
(Synonym: Apo-citalopram)		[1] Citalopram[2] D00822 ,
D07704 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
75 Clarithromycin
(Synonym: Apo-clarithromycin XL)		[1] Clarithromycin[1] D00276 --[8] 6, 63, 84, 96, 97, 222, 228, 299
76 Clavulanic acid
(Synonym: Apo-amoxicillin-clavulanate)		[4] AMOXICILLIN; Augmentin; Clavulanate; CLAVULANIC ACID[1] D07711 --[1] 299
77 Clindamycin
(Synonym: Apo-clindamycin)		[2] Clindamycin; Dalacin C phosphate[4] D00277 ,
D01073 ,
D01990 ,
D02132 		--[2] 46, 299
78 Clobazam
(Synonym: Apo-clobazam)		[1] CLOBAZAM[1] D01253 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 140, 144
79 Clobetasol propionate
(Synonym: PMS-clobetasol Scalp Application)		[1] Clobetasol propionate[2] D01272 ,
D07715 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 46, 162
80 Clonazepam
(Synonym: Apo-clonazepam)		[1] Clonazepam[1] D00280 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6
81 Clonidine
(Synonym: Apo-clonidine)		[4] Clonidin; Clonidina; Clonidine; Clonidine hydrochloride[2] D00281 ,
D00604 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78
82 Clopidogrel
(Synonym: Clopidogrel Apotex)		[1] Clopidogrel[4] D00769 ,
D07729 ,
D10823 ,
D10824 		[1] P2RY12 💬[1] Platelet activation 💬[2] 49, 86
83 Colesevelam
(Synonym: Apo-colesevelam)		[2] Cholestagel; Colesevelam[2] D03582 ,
D07743 		--[2] 96, 260
84 Cromoglicic acid
(Synonym: Apo-cromolyn Sterules)		[4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium[2] D00526 ,
D07753 		--[3] 2, 85, 98
85 Cyclosporine
(Synonym: Apo-cyclosporine Oral Solution)		[10] CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
86 D-glucose
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		[2] D-glucose; Glucose[1] D00009 --[3] 49, 86, 88
87 Dabigatran etexilate
(Synonym: Apo-dabigatran)		[1] Dabigatran etexilate[1] D07144 [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[1] 51
88 Dalfampridine
(Synonym: 4-AP)		[7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; FAMPYRA[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14
89 Darifenacin
(Synonym: Apo-darifenacin)		[2] Darifenacin; Emselex[2] D01699 ,
D03654 		[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13
90 Darunavir
(Synonym: Apo-darunavir)		[1] Darunavir[1] D03656 --[1] 2
91 Dasatinib
(Synonym: Apo-dasatinib)		[1] Dasatinib[2] D03658 ,
D06414 		[8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85
92 Deferasirox
(Synonym: Apo-deferasirox)		[2] Deferasirox; EXJADE[1] D03669 --[3] 254, 284, 286
93 Desmopressin
(Synonym: Apo-desmopressin)		[5] DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288
94 Desogestrel
(Synonym: Apri 28)		[2] Desogestrel; Désogestrel[1] D02367 [2] ESR1,
PGR 💬		[11] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 230
95 Dexamethasone
(Synonym: Apo-dexamethasone)		[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex[9] D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
96 Dextromethorphan
(Synonym: AP-Hist DM)		[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
97 Diclofenac
(Synonym: Apo-diclo Rapide 50 Mg Tablets)		[3] Diclofenac; Diclofenac sodium; Diclofenac SR[3] D00903 ,
D00904 ,
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
98 Digoxin
(Synonym: Apo-digoxin)		[1] Digoxin[1] D00298 [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 8, 46, 210
99 Diltiazem
(Synonym: Apo-diltiaz CD)		[2] Diltiazem; Diltiazem Hydrochloride[3] D00616 ,
D03830 ,
D07845 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86
100 Dimethyl fumarate
(Synonym: Apo-dimethyl Fumarate)		[3] DIMETHYL FUMARATE; Dimethylfumarat; TECFIDERA[1] D03846 [1] KEAP1 💬[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 49, 51, 86, 296
101 Diphenhydramine
(Synonym: Aphenap)		[2] Diphenhydramine; Diphenhydramine hydrochloride[6] D00300 ,
D00669 ,
D02419 ,
D03285 ,
D03360 ,
D03854 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
102 Dipivefrin
(Synonym: Apo-dipivefrin)		[2] Dipivefrin; Dipivefrine[1] D02349 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
103 Dipyridamole
(Synonym: Apo-dipyridamole)		[1] Dipyridamole[1] D00302 [2] PDE4A,
PDE5A 💬		[6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 46, 49, 51, 66, 96, 224
104 Domperidone
(Synonym: Apo-domperidone - Tab 10mg)		[1] Domperidone[2] D01745 ,
D07868 		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230
105 Donepezil
(Synonym: Apo-donepezil)		[3] Aricept; Donepezil; Donepezil hydrochloride[2] D00670 ,
D07869 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
106 Dorzolamide
(Synonym: Apo-dorzo-timop)		[1] Dorzolamide[2] D00653 ,
D07871 		[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90
107 Doxazosin
(Synonym: Apo-doxazosin)		[2] CARDURA; DOXAZOSIN[2] D00608 ,
D07874 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 57, 67
108 Doxycycline
(Synonym: Apo-doxy Cap 100mg)		[4] Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets[5] D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876 		--[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
109 Duloxetine
(Synonym: Apo-duloxetine)		[3] CYMBALTA; Duloxetine; Duloxetine hydrochloride[2] D01179 ,
D07880 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13
110 Dutasteride
(Synonym: Apo-dutasteride)		[2] Dutasterida; DUTASTERIDE[1] D03820 [2] SRD5A1,
SRD5A2 💬		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2
111 Efavirenz
(Synonym: Apo-efavirenz-emtricitabine-tenofovir)		[2] Efavirenz; SUSTIVA[1] D00896 --[1] 265
112 Emtricitabine
(Synonym: Apo-efavirenz-emtricitabine-tenofovir)		[2] Emtricitabine; TRUVADA[1] D01199 --[4] 25, 93, 265, 325
113 Enalapril
(Synonym: Apo-enalapril Tab 10mg)		[2] Enalapril; Enalapril Maleate[2] D00621 ,
D07892 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
114 Entacapone
(Synonym: Apo-entacapone)		[5] COMTAN; Comtess; ENTACAPONA; Entacapone; Stalevo[1] D00781 [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17
115 Entecavir
(Synonym: Apo-entecavir)		[1] Entecavir[2] D04008 ,
D07896 		--[6] 46, 56, 96, 97, 107, 271
116 Eplerenone
(Synonym: Apo-eplerenone)		[1] Eplerenone[1] D01115 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[4] 75, 113, 210, 215
117 Erlotinib
(Synonym: Apo-erlotinib)		[1] Erlotinib[2] D04023 ,
D07907 		[1] EGFR 💬[48] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬[1] 94
118 Escitalopram
(Synonym: Apo-escitalopram)		[3] Citalopram; Escitalopram; Escitalopram oxalate[3] D02567 ,
D07704 ,
D07913 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 2, 6, 13
119 Esomeprazole
(Synonym: Apo-esomeprazole)		[3] Esomeprazole; Nexium; Omeprazole[4] D01984 ,
D04056 ,
D07917 ,
D09339 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299
120 Ethanol
(Synonym: Green Apple Hand Sanitizer)		[3] Alcohol; Ethanol; Prednisone[4] D00068 ,
D02798 ,
D04855 ,
D06542 		--[7] 13, 51, 58, 97, 279, 280, 298
121 Ethinylestradiol
(Synonym: Apri 21)		[3] Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 777[1] D00554 [1] ESR1 💬[9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 13, 46, 49, 299
122 Ezetimibe
(Synonym: Apo-ezetimibe)		[2] Ezetimibe; Ezetrol[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
123 Factor IX Complex (Human)
(Synonym: APCC)		[1] Prothrombin Complex Concentrate---[1] 288
124 Famciclovir
(Synonym: Apo-famciclovir)		[1] Famciclovir[1] D00317 --[1] 13
125 Famotidine
(Synonym: Apo-famotidine Injectable)		[2] FAMOTIDINA; Famotidine[1] D00318 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[7] 6, 46, 61, 86, 98, 107, 300
126 Fenofibrate
(Synonym: Apo-feno-super)		[1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[5] 8, 79, 93, 94, 265
127 Fentanyl
(Synonym: Apo-fentanyl Matrix)		[1] Fentanyl[2] D00320 ,
D01399 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[4] 46, 70, 215, 231
128 Fesoterodine
(Synonym: Apo-fesoterodine)		[1] Fesoterodine[1] D07226 [2] CHRM2,
CHRM3 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6
129 Finasteride
(Synonym: Apo-finasteride)		[1] Finasteride[1] D00321 [1] SRD5A2 💬[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6
130 Fingolimod
(Synonym: Apo-fingolimod)		[2] FINGOLIMOD; GILENYA[1] D10001 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 14, 156
131 Flavoxate
(Synonym: Apo-flavoxate)		[1] Flavoxate[2] D00718 ,
D07961 		[16] PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[18] Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
132 Flecainide
(Synonym: Apo-flecainide)		[3] Flecainide; FLECAINIDE ACETATE; Flecainidum[2] D00638 ,
D07962 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6
133 Fluconazole
(Synonym: Apo-fluconazole-150)		[2] Diflucan; FLUCONAZOLE[2] D00322 ,
D01429 		--[2] 96, 225
134 Fluoxetine
(Synonym: Apo-fluoxetine)		[5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[2] D00326 ,
D00823 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206
135 Fluticasone propionate
(Synonym: Apo-fluticasone HFA)		[3] Flovent; Fluticasone; FLUTICASONE PROPIONATE[1] D01708 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 228
136 Fulvestrant
(Synonym: Apo-fulvestrant)		[2] Faslodex; Fulvestrant[1] D01161 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 49, 86
137 Furosemide
(Synonym: Apo Furosemide Tab 40mg)		[2] Furosemide; Furosemide Injection[1] D00331 [1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[1] 6
138 Gabapentin
(Synonym: Apo-gabapentin Tablets)		[4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN[1] D00332 [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298
139 Galantamine
(Synonym: Apo-galantamine)		[2] Galantamine; Galantamine hydrobromide[2] D02173 ,
D04292 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[2] 6, 127
140 Gefitinib
(Synonym: Apo-gefitinib)		[1] Gefitinib[1] D01977 [1] EGFR 💬[48] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬[1] 75
141 Glycerin
(Synonym: Jejuen Waterful Applemango Sheet Mask)		[3] Bee venom; Glycerine; Glycerol[1] D00028 --[6] 6, 13, 79, 265, 316, 317
142 Haloperidol
(Synonym: Apo-haloperidol LA Injectable)		[1] Haloperidol[2] D00136 ,
D01898 		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
143 Hydralazine
(Synonym: Apresoline)		[1] Hydralazine[2] D01302 (Name: Apresoline (TN)),
D08044 		[1] AOC3 💬[5] Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism 💬[1] 67
144 Hydrochlorothiazide
(Synonym: Apo-ramipril/hctz)		[2] Esidrix; Hydrochlorothiazide[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
145 Hydrocortisone
(Synonym: Apres Peel Soothing Balm)		[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[11] 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
146 Hydrogen peroxide
(Synonym: Aplicare Hydrogen Peroxide)		[1] Hydrogen peroxide[1] D00008 --[1] 13
147 Hydromorphone
(Synonym: Apo-hydromorphone CR)		[1] Hydromorphone[2] D00839 ,
D08047 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70
148 Hydroxychloroquine
(Synonym: Apo-hydroxyquine)		[3] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; Plaquenil[1] D08050 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
149 Hydroxyurea
(Synonym: Apo-hydroxyurea)		[1] Hydroxyurea[1] D00341 [1] RRM2 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
150 Ibuprofen
(Synonym: Aprofen Regular Strength)		[2] Ibuprofen; IBUPROFEN 200MG[4] D00126 ,
D01122 ,
D04490 ,
D06606 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
151 Imatinib
(Synonym: Apo-imatinib)		[4] Gleevec; GLIVEC; Imatinib; Imatinib Mesylate[2] D01441 ,
D08066 		[3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
152 Imiquimod
(Synonym: Apo-imiquimod)		[1] Imiquimod[1] D02500 [1] TLR7 💬[5] Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬[2] 34, 51
153 Indapamide
(Synonym: Apo-perindopril-indapamide)		[1] Indapamide[2] D00345 ,
D06401 		[1] SLC12A3 💬-[1] 13
154 Indomethacin
(Synonym: Apo Indomethacin Cap 50mg)		[2] INDOMETACIN; Indomethacin[3] D00141 ,
D01565 ,
D02110 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298
155 Ipratropium
(Synonym: Apo-ipravent Solution - Inh 250mcg/ml)		[1] Ipratropium[1] D02212 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 6, 86
156 Irbesartan
(Synonym: Apo-irbesartan/hctz)		[2] Aprovel; IRBESARTAN[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 66, 167, 168, 222
157 Ketoconazole
(Synonym: Apo-ketoconazole)		[2] Ketoconazole; NIZORAL[1] D00351 [1] CYP17A1 💬[6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[3] 8, 13, 75
158 Ketorolac
(Synonym: Apo-ketorolac)		[2] Ketorolac; Ketorolac Tromethamine[2] D00813 ,
D08104 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 70, 226
159 Lacosamide
(Synonym: Apo-lacosamide)		[1] Lacosamide[1] D07299 [2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[3] 2, 46, 149
160 Lactulose
(Synonym: Apo-lactulose)		[1] Lactulose[1] D00352 --[3] 13, 96, 291
161 Lamivudine
(Synonym: Apo-abacavir-lamivudine)		[4] COMBIVIR; Epivir; Lamivudine; Triumeq[1] D00353 --[7] 2, 26, 42, 46, 135, 265, 325
162 Lamotrigine
(Synonym: Apo-lamotrigine)		[2] Lamictal; LAMOTRIGINE[1] D00354 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 13, 34, 38, 114, 144
163 Lansoprazole
(Synonym: Apo-lansoprazole-amoxicillin-clarithromycin)		[1] Lansoprazole[1] D00355 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299
164 Leflunomide
(Synonym: Apo-leflunomide)		[3] Arava; LEFLUNOMIDE; Leflunomidum[1] D00749 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
165 Lenalidomide
(Synonym: Apo-lenalidomide)		[2] Lenalidomide; Revlimid[1] D04687 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331
166 Letrozole
(Synonym: Apo-letrozole)		[1] Letrozole[1] D00964 [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[2] 81, 89
167 Levetiracetam
(Synonym: Apo-levetiracetam)		[2] KEPPRA; Levetiracetam[1] D00709 [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
168 Levodopa
(Synonym: Apo-levocarb - Tab 25mg/250mg)		[8] DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 2, 4, 6, 17, 90, 140, 164, 201
169 Levofloxacin
(Synonym: Apo-levofloxacin)		[2] Levaquin; Levofloxacin[2] D00588 ,
D08120 		--[5] 46, 53, 84, 85, 299
170 Lidocaine
(Synonym: Aprizio Pak II)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[3] D00358 ,
D02086 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
171 Linezolid
(Synonym: Apo-linezolid)		[1] LINEZOLID[1] D00947 --[1] 299
172 Lisinopril
(Synonym: Apo-lisinopril Tablet - 20mg)		[2] Lisinopril; Zestril[2] D00362 ,
D08131 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
173 Lithium carbonate
(Synonym: Apo-lithium Carbonate)		[2] Lithium; Lithium Carbonate[1] D00801 --[6] 2, 13, 17, 18, 19, 127
174 Loperamide
(Synonym: Apo-loperamide)		[2] Loperamide; Loperamide hydrochloride[3] D00729 ,
D07113 ,
D08144 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97
175 Loratadine
(Synonym: Apo-loratadine)		[2] Loratadina; Loratadine[1] D00364 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98
176 Lorazepam
(Synonym: Apo-lorazepam Tab 2mg)		[1] Lorazepam[1] D00365 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 36, 231
177 Losartan
(Synonym: Apo-losartan/hctz)		[3] Cozaar; Losartan; Losartan Potassium[2] D00357 ,
D08146 		[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
178 Magnesium oxide
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		[1] Magnesium Oxide[1] D01167 --[3] 6, 166, 291
179 Medroxyprogesterone acetate
(Synonym: Apo-medroxy)		[1] Medroxyprogesterone[2] D00951 ,
D08166 		[1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[6] 13, 35, 46, 49, 51, 60
180 Megestrol acetate
(Synonym: Apo-megestrol)		[1] Megestrol acetate[2] D00952 ,
D08167 		[1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 76
181 Meloxicam
(Synonym: Apo-meloxicam)		[1] Meloxicam[1] D00969 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 46, 49, 271, 296
182 Memantine
(Synonym: Apo-memantine)		[3] EBIXA; MEMANTINE; Memantine hydrochloride[2] D04905 ,
D08174 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
183 Mesalazine
(Synonym: Apriso)		[10] 5-AminoSalicylic Acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; Mesalazine; Mesalazinum; MEZAVANT; Pentasa; Salofalk[1] D00377 (Name: Apriso (TN))--[4] 46, 96, 97, 164
184 Metformin
(Synonym: Apo-metformin)		[5] Metformin; Metformin HCl; Metformin Hydrochloride; Metformina; Metformine[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
185 Methimazole
(Synonym: Apo-methimazole)		[1] Methimazole[1] D00401 [1] TPO 💬[4] Autoimmune thyroid disease, Metabolic pathways, Thyroid hormone synthesis, Tyrosine metabolism 💬[1] 50
186 Methotrexate
(Synonym: Apo-methotrexate)		[6] Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
187 Methyldopa
(Synonym: Apo Methazide 25)		[1] Methyldopa[2] D00405 ,
D08205 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 323
188 Methylphenidate
(Synonym: Apo-methylphenidate SR)		[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[2] D01296 (Name: APTENSIO XR),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206
189 Metoclopramide
(Synonym: Apo-metoclop Tab 10mg)		[1] METOCLOPRAMIDE[3] D00726 ,
D02213 ,
D05008 		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 51
190 Metoprolol
(Synonym: Apo-metoprolol SR)		[2] Metoprolol; Metoprolol succinate[3] D00601 ,
D02358 ,
D05011 		[1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226
191 Metronidazole
(Synonym: Apo-metronidazole)		[3] Flagyl; Metronidazol; Metronidazole[3] D00409 ,
D05016 ,
D05017 		--[8] 46, 51, 63, 94, 95, 96, 97, 291
192 Midazolam
(Synonym: Apo-midazolam Injectable 1 mg/ml)		[2] Midazolam; Midazolam injection[3] D00550 ,
D00696 ,
D05028 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
193 Midodrine
(Synonym: Apo-midodrine)		[2] Midodrine; MIDODRINE HYDROCHLORIDE[2] D01307 ,
D08220 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58
194 Milrinone
(Synonym: Apo-milrinone Injectable)		[1] Milrinone[2] D00417 ,
D02085 		[2] PDE3A,
PDE3B 💬		[11] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 294
195 Mineral oil
(Synonym: Apj Hemorrhoidal)		[1] Paraffin Oil[1] D05042 --[1] 291
196 Minoxidil
(Synonym: Apo-gain Liq 20mg/ml)		[1] MINOXIDIL[1] D00418 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[1] 179
197 Modafinil
(Synonym: Apo-modafinil)		[2] MODAFINIL; Provigil[1] D01832 --[5] 6, 13, 49, 93, 113
198 Mometasone furoate
(Synonym: Apo-mometasone)		[3] Mometasone; MOMETASONE FUROATE; Nasonex[1] D00690 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 162
199 Montelukast
(Synonym: Apo-montelukast Sodium)		[3] Montelukast; MONTELUKAST SODIUM; Singulair[2] D00529 ,
D08229 		[1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228
200 Moxifloxacin
(Synonym: Apo-moxifloxacin)		[2] Moxifloxacin; Moxifloxacin Hydrochloride[2] D00874 ,
D08237 		--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
201 Mycophenolate mofetil
(Synonym: Apo-mycophenolate Mofetil)		[3] CELLCEPT; Mycophenolate Mofetil; Mycophenolate mofetil TEVA[3] D00752 ,
D05094 ,
D05095 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
202 Mycophenolic acid
(Synonym: Apo-mycophenolic Acid)		[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
203 Nabilone
(Synonym: Apo-nabilone)		[1] NABILONE[1] D05099 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[2] 6, 13
204 Nadolol
(Synonym: Apo-nadolol)		[1] Nadolol[1] D00432 [2] ADRB1,
ADRB2 💬		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
205 Naltrexone
(Synonym: Apo-naltrexone)		[2] Naltrexone; Naltrexone Hydrochloride[2] D02095 ,
D05113 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
206 Naproxen
(Synonym: Apo-naproxen)		[5] Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[1] D00118 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271
207 Nebivolol
(Synonym: Apo-nebivolol)		[1] Nebivolol[1] D05127 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167
208 Neomycin
(Synonym: Antibiotic Application)		[1] Neomycin[1] D08260 --[3] 96, 97, 296
209 Nevirapine
(Synonym: Apo-zidovudine-lamivudine-nevirapine)		[1] Nevirapine[1] D00435 --[1] 265
210 Nicotinamide
(Synonym: Appedrine)		[4] Ginseng; Multivitamin; Niacinamide; Nicotinamide[1] D00036 --[11] 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
211 Nifedipine
(Synonym: Apo-nifed Pa)		[1] Nifedipine[1] D00437 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 50, 81
212 Nitroglycerin
(Synonym: Apo-nitroglycerin)		[2] Nitroglycerin; Nitroglycerine[1] D00515 --[2] 46, 51
213 Nortriptyline
(Synonym: Apo-nortriptyline - Cap 10mg)		[2] Nortriptyline; Nortriptyline hydrochloride[2] D00816 ,
D08288 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226
214 Olanzapine
(Synonym: Olanzapine Apotex)		[2] Olanzapine; Zyprexa[2] D00454 ,
D06623 		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
215 Olive oil
(Synonym: Rhodd Ato Repair Body So Ap)		[1] Olive Oil[1] D03311 --[3] 13, 49, 53
216 Omeprazole
(Synonym: Not Applicable)		[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
217 Ondansetron
(Synonym: Apo-ondansetron)		[1] Ondansetron[2] D00456 ,
D00678 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[4] 6, 97, 107, 231
218 Oxcarbazepine
(Synonym: Apo-oxcarbazepine)		[2] Oxcarbazepine; Trileptal[1] D00533 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13
219 Oxybutynin
(Synonym: Apo-oxybutynin)		[1] Oxybutynin[2] D00465 ,
D00722 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53
220 Oxycodone
(Synonym: Oxycodone Apap)		[3] Oxycodone; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen[3] D03783 ,
D05312 ,
D05462 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
221 Paclitaxel
(Synonym: Apo-paclitaxel Injectable)		[1] Paclitaxel[2] D00491 ,
D05333 		[9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[2] 46, 85
222 Pantoprazole
(Synonym: Apo-pantoprazole)		[1] Pantoprazole[2] D02593 ,
D05353 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65
223 Paroxetine
(Synonym: Apo-paroxetine)		[1] Paroxetine[4] D02260 ,
D02362 ,
D05374 ,
D05375 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85
224 Pectin
(Synonym: SMITH BROS WARM APPLE PIE WITH CINNAMON FLAVOR Warming Throat)		[1] Pectin[1] D02316 --[1] 96
225 Pegfilgrastim
(Synonym: pegfilgrastim-apgf)		[1] Pegfilgrastim[1] D06889 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[1] 60
226 Perindopril
(Synonym: Apo-perindopril-indapamide)		[2] Coversyl; Perindopril[2] D00624 ,
D03753 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 58, 113, 167, 222
227 Petrolatum
(Synonym: Apj Hemorrhoidal)		[1] Petrolatum[1] D05331 --[3] 35, 158, 162
228 Phenoxymethylpenicillin
(Synonym: Apo Pen Vk)		[0] [3] D00497 ,
D02506 ,
D05411 		--[3] 13, 97, 215
229 Phenylephrine
(Synonym: Neocitran Extra Strength Cold & Sinus Night - Apple Cinnamon)		[1] Phenylephrine[2] D00511 ,
D08365 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
230 Pioglitazone
(Synonym: Apo-pioglitazone)		[1] Pioglitazone[2] D00945 ,
D08378 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
231 Piperazine [1] Piperazine[6] D00807 ,
D01393 ,
D02127 ,
D02145 (Name: Camin AP (TN)),
D05486 ,
D06224 		--[2] 58, 272
232 Posaconazole
(Synonym: Apo-posaconazole)		[2] Noxafil; POSACONAZOLE[1] D02555 --[4] 60, 65, 96, 299
233 Pramipexole
(Synonym: Apo-pramipexole)		[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
234 Pravastatin
(Synonym: Apo-pravastatin)		[2] Pravastatin; Pravastatin sodium[2] D00893 ,
D08410 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
235 Prednisone
(Synonym: Apo Prednisone Tab 1mg USP)		[3] Prednisona; Prednisone; RAYOS[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
236 Pregabalin
(Synonym: Apo-pregabalin)		[2] Lyrica; Pregabalin[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
237 Propranolol
(Synonym: Apo-propranolol)		[3] Propanolol; Propranolol; Propranolol Hydrochloride[2] D00483 ,
D08443 		[3] ADRB1,
ADRB2,
ADRB3 💬		[12] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 158, 167, 215, 227, 278, 296
238 Prucalopride
(Synonym: Apo-prucalopride)		[2] Prucalopride; Resolor[1] D09205 [1] HTR4 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬[3] 13, 51, 96
239 Pseudoephedrine
(Synonym: Aprodine)		[1] Pseudoephedrine[4] D00485 ,
D05648 ,
D05649 ,
D08449 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17
240 Pyridoxine
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		[2] Pyridoxine; Vitamin B6[2] D02179 ,
D08454 		--[5] 6, 93, 145, 206, 320
241 Quetiapine
(Synonym: Apo-quetiapine Fumarate)		[2] Quetiapine; Seroquel[2] D00458 ,
D08456 		[2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13
242 Quinapril
(Synonym: Apo-quinapril)		[1] Accuretic[2] D00459 ,
D03752 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 19
243 Quinidine
(Synonym: Apo Quinidine Tab 200mg)		[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate[4] D00642 ,
D00643 ,
D02272 ,
D08458 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
244 Rabeprazole
(Synonym: Apo-rabeprazole)		[1] Rabeprazole[2] D00724 ,
D08463 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51
245 Raloxifene
(Synonym: Apo-raloxifene)		[2] Raloxifene; Raloxifene hydrochloride[2] D02217 ,
D08465 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 46
246 Ramipril
(Synonym: Apo-ramipril/hctz)		[1] Ramipril[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
247 Ranitidine
(Synonym: Aptidine 75)		[1] Ranitidine[2] D00422 ,
D00673 		[1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65
248 Rasagiline
(Synonym: Apo-rasagiline)		[4] AZILECT; Rasagilina; Rasagiline; Rasagiline mesylate[3] D02562 ,
D08469 ,
D10829 		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 2, 5, 6, 13, 17, 58, 66
249 Repaglinide
(Synonym: Apo-repaglinide)		[1] Repaglinide[1] D00594 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[3] 6, 21, 299
250 Riboflavin
(Synonym: Appedrine)		[2] Riboflavin; Vitamin B2[3] D00050 ,
D01622 ,
D01913 		--[8] 13, 38, 46, 96, 97, 162, 168, 265
251 Riluzole
(Synonym: Apo-riluzole)		[2] Rilutek; Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
252 Risedronic acid
(Synonym: Apo-risedronate)		[3] Risedronate; RISEDRONATE SODIUM; Risedronic acid[3] D00942 ,
D03234 ,
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
253 Risperidone
(Synonym: Apo-risperidone)		[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
254 Rivastigmine
(Synonym: Apo-rivastigmine)		[3] EXELON; RIVASTIGMINE; Rivastigmine Transdermal System[2] D02558 ,
D03822 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
255 Ropinirole
(Synonym: Apo-ropinirole)		[3] REQUIP; ROPINIROLE; Ropinirole Hydrochloride[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
256 Rosuvastatin
(Synonym: Apo-rosuvastatin)		[3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
257 Royal jelly
(Synonym: Apis Mellifera Secretion)		[1] Royal jelly[1] D09754 --[1] 49
258 Salbutamol
(Synonym: Apo-salvent Sterules)		[3] Albuterol; Salbutamol; Ventolin[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[14] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299
259 Salicylic acid
(Synonym: Medicated Apricot Scrub)		[2] 2-Hydroxybenzoic acid; Salicylic acid[1] D00097 --[1] 97
260 Saxagliptin
(Synonym: Apo-saxagliptin)		[1] Saxagliptin[1] D08996 [1] DPP4 💬[1] Protein digestion and absorption 💬[1] 299
261 Sertraline
(Synonym: Apo-sertraline)		[1] Sertraline[2] D00825 ,
D02360 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206
262 Sildenafil
(Synonym: Apo-sildenafil)		[6] Mysildecard; Revatio; Sildenafil; Sildenafil citrate; SILDENAFILO; Viagra[2] D02229 ,
D08514 (Name: Aphrodil (TN))		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
263 Silodosin
(Synonym: Apo-silodosin)		[2] Silodosin; Silodyx[1] D01965 [1] ADRA1A 💬[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 6, 13
264 Simvastatin
(Synonym: Apo-simvastatin)		[3] Simvastatin; Simvastatina; Simvastatine[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
265 Sodium bicarbonate
(Synonym: Not Applicable)		[1] Sodium Bicarbonate[1] D01203 --[1] 299
266 Sodium chloride
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		[6] Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; Sporanox[1] D02056 --[21] 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
267 Sodium fluoride
(Synonym: Pcxx Watermelon Apf G)		[2] Beam; Sodium fluoride[1] D00943 --[1] 51
268 Solifenacin
(Synonym: Apo-solifenacin)		[2] Solifenacin; Solifenacin Succinate[2] D01269 ,
D08522 		[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53
269 Spironolactone
(Synonym: Apo-spirozide Tab)		[1] SPIRONOLACTONE[1] D00443 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[7] 58, 67, 86, 113, 210, 218, 225
270 Sucralfate
(Synonym: Apo-sucralfate - Tab 1g)		[1] Sucralfate[1] D00446 --[1] 98
271 Sulfamethoxazole
(Synonym: Apo-sulfatrim Oral Suspension)		[3] Bactrim; Sulfamethoxazole; Sulphamethoxazole[1] D00447 --[5] 44, 49, 61, 85, 299
272 Sulfasalazine
(Synonym: Apo Sulfasalazine Tab 500mg)		[3] Salazosulfapyridine; Salicylazosulfapyridine; SULFASALAZINE[1] D00448 --[6] 46, 86, 94, 107, 270, 271
273 Sulindac
(Synonym: Apo-sulin Tab 200mg)		[1] Sulindac[1] D00120 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 206
274 Tacrolimus
(Synonym: Apo-tacrolimus)		[2] Prograf; Tacrolimus[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
275 Tadalafil
(Synonym: Apo-tadalafil Pah)		[4] Adcirca; Cialis; Tadalafil; TADALAFILO[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210
276 Tamoxifen
(Synonym: Apo-tamox Tab 20mg)		[2] TAMOXIFEN; TAMOXIFEN CITRATE[2] D00966 ,
D08559 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 2, 86, 113, 227
277 Telmisartan
(Synonym: Apo-telmisartan)		[1] Telmisartan[1] D00627 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 67
278 Temozolomide
(Synonym: Apo-temozolomide)		[1] Temozolomide[1] D06067 --[1] 34
279 Tenofovir disoproxil
(Synonym: Apo-tenofovir)		[4] Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA[1] D01982 --[2] 93, 265
280 Terazosin
(Synonym: Apo-terazosin)		[1] Terazosin[2] D00610 ,
D08569 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 6
281 Terbinafine
(Synonym: Apo-terbinafine)		[1] Terbinafine[2] D02219 ,
D02375 		--[3] 96, 97, 271
282 Teriparatide
(Synonym: Apo-teriparatide Injection)		[4] Forsteo; Forteo; PTH 1-34; Teriparatide[1] D06078 [1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[7] 46, 65, 68, 70, 71, 235, 274
283 Tetrabenazine
(Synonym: Apo-tetrabenazine)		[2] Tetrabenazine; Xenazine[1] D08575 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
284 Tetracycline
(Synonym: Apo Tetra Tabs 250mg)		[2] Tetracyclin; Tetracycline[1] D00201 --[5] 13, 36, 46, 53, 97
285 Theophylline
(Synonym: Apo-theo ER)		[1] Theophylline[5] D00371 ,
D01712 ,
D02017 ,
D06103 ,
D06104 		[19] ADORA1,
ADORA2A,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[24] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
286 Thiamine
(Synonym: Appedrine)		[2] Thiamine; Vitamin B1[1] D08580 --[5] 8, 13, 93, 145, 265
287 Ticagrelor
(Synonym: Apo-ticagrelor)		[1] Ticagrelor[1] D09017 [1] P2RY12 💬[1] Platelet activation 💬[3] 36, 46, 85
288 Timolol
(Synonym: Apo-travoprost-timolol Pq)		[2] Timolol; TIMOLOL MALEATE[3] D00378 ,
D00603 ,
D08600 		[2] ADRB1,
ADRB2 💬		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227
289 Tipranavir
(Synonym: Aptivus)		[1] Tipranavir[2] D03843 ,
D08605 (Name: Aptivus (TN))		--[1] 265
290 Tobramycin
(Synonym: Apo-tobramycin)		[9] Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum[2] D00063 ,
D02542 		--[1] 299
291 Tolterodine
(Synonym: Apo-tolterodine)		[1] Tolterodine[2] D00646 ,
D01148 		[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53
292 Topiramate
(Synonym: Apo-topiramate)		[2] TOPAMAX; TOPIRAMATE[1] D00537 [36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193
293 Tramadol
(Synonym: Apo-tramadol)		[2] Tramadol; Ultracet[2] D01355 ,
D08623 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
294 Trazodone
(Synonym: Apo-trazodone Tablets 50mg)		[1] Trazodone[2] D00820 ,
D08626 		[4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 2
295 Triamcinolone
(Synonym: Apo-triamcinolone AQ)		[4] Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide[5] D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
296 Trifluoperazine [1] Trifluoperazine[3] D00799 ,
D01448 ,
D08636 (Name: Apo-trifluoperazine (TN))		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284
297 Trihexyphenidyl
(Synonym: Aparkane Tab 2mg)		[1] Trihexyphenidyl[2] D00787 ,
D08638 (Name: Apo-trihex (TN))		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6
298 Trimethoprim
(Synonym: Apo-sulfatrim Oral Suspension)		[2] Bactrim; Trimethoprim[2] D00145 ,
D06236 		--[8] 36, 44, 49, 60, 61, 85, 298, 299
299 Tryptophan
(Synonym: Apo-tryptophan)		[2] Propanoic acid; Tryptophan[1] D00020 --[2] 6, 75
300 Tyrosine
(Synonym: Appbutamone)		[4] Alanine; L-Tyrosine; Propanoic acid; Tyrosine[1] D00022 --[5] 6, 75, 86, 111, 298
301 Urea
(Synonym: Not Applicable)		[1] Urea[2] D00023 ,
D01749 		--[2] 72, 251
302 Valaciclovir
(Synonym: Apo-valacyclovir)		[1] Valacyclovir[3] D00398 ,
D08664 ,
D10518 		--[1] 65
303 Valganciclovir
(Synonym: Apo-valganciclovir)		[1] Valganciclovir[1] D02495 --[6] 28, 60, 85, 97, 299, 331
304 Valproic acid
(Synonym: Apo-valproic Acid)		[3] Valproate; VALPROATE SODIUM; Valproic Acid[1] D00399 [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
305 Valsartan
(Synonym: Apo-valsartan/hctz)		[3] Diovan; Entresto; Valsartan[1] D00400 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 57, 58, 66, 75, 218, 222, 224
306 Vardenafil
(Synonym: Apo-vardenafil)		[3] Levitra; Vardenafil; Vardenafilo[3] D02731 ,
D03260 ,
D08668 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[3] 13, 86, 299
307 Varenicline
(Synonym: Apo-varenicline)		[2] Champix; VARENICLINE[1] D08669 [2] CHRNA4,
CHRNB2 💬		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[2] 6, 18
308 Venlafaxine
(Synonym: Apo-venlafaxine XR)		[2] Venlafaxine; Venlafaxine Hydrochloride[2] D00821 ,
D08670 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46
309 Verapamil
(Synonym: Apo-verap Tab 80mg)		[2] Verapamil; Verapamil SR[2] D00619 ,
D02356 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 96, 140, 167
310 Vitamin A
(Synonym: Appedrine)		[1] Vitamin A[2] D00069 ,
D06543 		[2] RARA,
RARB 💬		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90
311 Vitamin D
(Synonym: Appedrine)		[3] Calciferol; Cod liver oil; Vitamin D---[24] 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
312 Voriconazole
(Synonym: Apo-voriconazole)		[2] Vfend; VORICONAZOLE[1] D00578 --[2] 60, 299
313 Warfarin
(Synonym: Apo-warfarin)		[2] Warfarin; Warfarin Sodium[3] D00564 ,
D01280 ,
D08682 		[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
314 Zidovudine
(Synonym: Apo-abacavir-lamivudine-zidovudine)		[3] COMBIVIR; Retrovir; Zidovudine[1] D00413 --[7] 25, 26, 94, 135, 265, 325, 331
315 Zinc
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		[3] Nicotinamide; Wilzin; Zinc---[4] 2, 113, 171, 299
316 Zolmitriptan
(Synonym: Apo-zolmitriptan)		[1] Zolmitriptan[1] D00415 [2] HTR1B,
HTR1D 💬		[4] Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6
317 Zolpidem
(Synonym: Apo-zolpidem ODT)		[2] Zolpidem; Zolpidem Tartrate[2] D00706 ,
D08690 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46
318 Zopiclone
(Synonym: Apo-zopiclone)		[1] Zopiclone[1] D01372 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6