Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Artesunate 1件: Artesunate1件: Artesunate 💬 --4件: 18, 66, 86, 96 💬
2 Baclofen 1件: Baclofen1件: Baclofen 💬 2件: GABBR1,
GABBR2 💬 		8件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬8件: 2, 10, 13, 18, 65, 70, 149, 206 💬
3 Bupropion 2件: Bupropion; Bupropion Hydrochloride3件: Bupropion hydrochloride ,
Bupropion ,
Bupropion hydrobromide 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 8, 18, 21, 96, 97, 171, 298 💬
4 Calcitriol 1件: Calcitriol1件: Calcitriol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬11件: 18, 37, 46, 49, 66, 96, 158, 223, 235, 238, 326 💬
5 Citalopram 1件: Citalopram2件: Citalopram hydrobromide ,
Citalopram 💬 		1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127 💬
6 Deferiprone 1件: DEFERIPRONE1件: Deferiprone 💬 --7件: 2, 6, 18, 121, 122, 139, 233 💬
7 Elamipretide 1件: ELAMIPRETIDE2件: Elamipretide ,
Elamipretide hydrochloride 💬 		--3件: 18, 21, 324 💬
8 Erythropoietin 3件: EPOETIN ALFA; Erythropoietin; RhEPO4件: Epoetin alfa ,
Epoetin epsilon ,
Epoetin theta ,
Epoetin zeta 💬 		1件: EPOR 💬 7件: Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬11件: 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
9 Etravirine 2件: ETRAVIRINA; Etravirine1件: Etravirine 💬 --1件: 18 💬
10 Flumazenil 1件: Flumazenil1件: Flumazenil 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		9件: Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206 💬
11 Fursultiamine 1件: Fursultiamine2件: Fursultiamine ,
Fursultiamine hydrochloride 💬 		--2件: 6, 18 💬
12 Gabapentin 3件: Gabapentin; GABAPENTINA; Gabapentine1件: Gabapentin 💬 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		10件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬7件: 6, 13, 18, 19, 70, 226, 298 💬
13 Ginkgo biloba 1件: Ginkgo biloba1件: Ginkgo 💬 --4件: 13, 18, 47, 90 💬
14 Idebenone 1件: Idebenone1件: Idebenone 💬 --9件: 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
15 Interferon Gamma 1件: Interferon Gamma---9件: 18, 65, 85, 96, 107, 228, 299, 301, 326 💬
16 Interferon gamma-1b 1件: Interferon gamma-1b1件: Interferon gamma-1b 💬 2件: IFNGR1,
IFNGR2 💬 		18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬7件: 18, 65, 85, 228, 299, 301, 326 💬
17 Iron 1件: Iron1件: Ferrous fumarate 💬 --7件: 18, 60, 96, 97, 238, 254, 284 💬
18 Lenograstim 2件: G-CSF; Lenograstim1件: Lenograstim 💬 1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬8件: 2, 13, 16, 18, 19, 57, 65, 97 💬
19 Leucine 2件: L-leucine; Leucine1件: Leucine 💬 --13件: 5, 6, 7, 18, 19, 65, 96, 97, 127, 280, 283, 284, 299 💬
20 Lithium carbonate 1件: Lithium Carbonate1件: Lithium carbonate 💬 --6件: 2, 13, 17, 18, 127, 310 💬
21 LX2006 1件: LX2006---1件: 18 💬
22 Methylprednisolone 3件: Methylprednisolon; METHYLPREDNISOLONE; METHYLPREDNISOLONE ACETATE2件: Methylprednisolone ,
Methylprednisolone acetate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
23 Nerve Growth Factor 1件: Nerve Growth Factor---5件: 2, 3, 18, 53, 90 💬
24 Nicotinamide 2件: Niacinamide; Nicotinamide1件: Niacinamide 💬 --19件: 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
25 Nicotinamide riboside 2件: Nicotinamide Riboside; Nicotinamide Riboside Chloride---14件: 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
26 Nomlabofusp 2件: CTI-1601; Nomlabofusp---1件: 18 💬
27 Omaveloxolone 1件: Omaveloxolone1件: Omaveloxolone 💬 1件: NFE2L2 💬 7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18 💬
28 Phenylbutyric acid 2件: PHENYLBUTYRATE; Sodium phenylbutyrate1件: Sodium phenylbutyrate 💬 --5件: 2, 3, 8, 18, 251 💬
29 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬48件: 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
30 Prednisone 2件: PREDNISONA; PREDNISONE1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
31 Resveratrol 2件: Resveratrol; Trans-Resveratrol---10件: 2, 6, 8, 18, 46, 57, 89, 97, 113, 299 💬
32 Riluzole 1件: Riluzole1件: Riluzole 💬 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		24件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
33 Rosuvastatin 2件: Rosuvastatin; ROSUVASTATIN CALCIUM2件: Rosuvastatin calcium ,
Rosuvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬16件: 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
34 Taltirelin 1件: Taltirelin---1件: 18 💬
35 Tocotrienol 1件: Tocotrienol---4件: 18, 21, 156, 299 💬
36 Trehalose 2件: Cabaletta; Trehalose---4件: 2, 6, 18, 113 💬
37 Troriluzole 1件: Troriluzole2件: Troriluzole ,
Troriluzole hydrochloride 💬 		14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		24件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬1件: 18 💬
38 Varenicline 2件: Varenicline; VARENICLINE TARTRATE2件: Varenicline tartrate ,
Varenicline 💬 		2件: CHRNA4,
CHRNB2 💬 		5件: Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction 💬4件: 6, 18, 53, 298 💬
39 Vatiquinone 2件: Alpha-tocotrienol quinone; VATIQUINONE1件: Vatiquinone 💬 --2件: 18, 21 💬
40 VO659 1件: VO659---2件: 8, 18 💬