Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Apomorphine 2件: Apomorphine; Apomorphine hydrochloride2件: Apomorphine hydrochloride ,
Apomorphine 💬 		2件: DRD1,
DRD2 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7 💬
2 Bepranemab 1件: Bepranemab1件: Bepranemab 💬 1件: MAPT 💬 4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 5 💬
3 Botulinum toxin type A 5件: Botulinum toxin A; Botulinum toxin type A; BTX-A; Incobotulinumtoxina; Onabotulinumtoxina2件: Botulinum toxin type A ,
Prabotulinumtoxin A 💬 		1件: SNAP25 💬 2件: Insulin secretion, Synaptic vesicle cycle 💬14件: 2, 5, 6, 7, 13, 15, 17, 47, 51, 70, 113, 149, 171, 226 💬
4 Davunetide 1件: Davunetide1件: Davunetide 💬 --3件: 5, 7, 127 💬
5 Donepezil 2件: Donepezil; Donepezil hydrochloride2件: Donepezil hydrochloride ,
Donepezil 💬 		1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬8件: 5, 6, 13, 46, 124, 127, 156, 206 💬
6 Droxidopa 2件: Droxidopa; L-dops1件: Droxidopa 💬 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170 💬
7 Emeramide 1件: Emeramide---2件: 5, 17 💬
8 Fasudil 2件: Fasudil; Fasudil hydrochloride2件: Fasudil hydrochloride ,
Fasudil 💬 		2件: ROCK1,
ROCK2 💬 		24件: Adherens junction, Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 2, 5, 6, 7, 51 💬
9 Flortaucipir 0件: 1件: Flortaucipir F 18 💬 1件: MAPT 💬 4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127 💬
10 Fludeoxyglucose (18F) 2件: 18F-FDG; Fludeoxyglucose F 181件: Fludeoxyglucose F 18 💬 --12件: 5, 6, 7, 8, 34, 41, 46, 84, 85, 96, 127, 300 💬
11 Flutemetamol 1件: Flutemetamol---5件: 5, 6, 7, 17, 127 💬
12 Flutemetamol (18F) 1件: Flutemetamol1件: Flutemetamol F 18 💬 --5件: 5, 6, 7, 17, 127 💬
13 Gosuranemab 1件: BMS-9861681件: Gosuranemab 💬 1件: MAPT 💬 4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 5 💬
14 Hydrogen 1件: Hydrogen---7件: 5, 6, 13, 17, 97, 226, 288 💬
15 Masitinib 2件: Masitinib; Masitinib mesylate1件: Masitinib 💬 1件: KIT 💬 11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬6件: 2, 5, 6, 13, 46, 96 💬
16 Nicotinamide 2件: Niacinamide; Nicotinamide1件: Niacinamide 💬 --20件: 2, 5, 6, 7, 8, 13, 17, 18, 21, 46, 49, 60, 63, 65, 67, 85, 97, 107, 162, 191 💬
17 Nicotinamide riboside 2件: Nicotinamide riboside; Nicotinamide riboside chloride---14件: 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
18 Nitrogen 1件: Nitrogen1件: Nitrogen 💬 --5件: 5, 6, 17, 211, 299 💬
19 Rasagiline 2件: Rasagiline; Rasagiline mesylate3件: Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		1件: MAO 💬 13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬5件: 2, 5, 6, 17, 66 💬
20 Riluzole 1件: Riluzole1件: Riluzole 💬 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		24件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬8件: 2, 3, 5, 8, 13, 17, 203, 206 💬
21 Rivastigmine 1件: Rivastigmine2件: Rivastigmine tartrate ,
Rivastigmine 💬 		1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬3件: 5, 6, 13 💬
22 Salsalate 1件: Salsalate1件: Salsalate 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5 💬
23 Suvorexant 1件: Suvorexant1件: Suvorexant 💬 2件: HCRTR1,
HCRTR2 💬 		2件: Hormone signaling, Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13 💬
24 THK-5351 1件: THK-5351---5件: 5, 6, 7, 17, 127 💬
25 Tideglusib 1件: Tideglusib---3件: 2, 5, 113 💬
26 Tolfenamic acid 1件: Tolfenamic acid1件: Tolfenamic acid 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5 💬
27 TPI-287 0件: ---2件: 5, 7 💬
28 Trihexyphenidyl 1件: Trihexyphenidyl2件: Trihexyphenidyl hydrochloride ,
Trihexyphenidyl 💬 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6 💬
29 Ubidecarenone 2件: Coenzyme Q10; COQ101件: Ubidecarenone 💬 --14件: 2, 5, 6, 8, 10, 46, 57, 86, 96, 107, 113, 193, 214, 215 💬
30 Valproic acid 3件: Valproate; Valproate sodium; Valproic acid3件: Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬13件: 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
31 Water 1件: Water1件: Water 💬 --28件: 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 64, 66, 67, 72, 85, 96, 97, 206, 225, 226, 230, 274, 278, 299 💬
32 Zoledronic acid 3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate5件: Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
33 Zolpidem 2件: Zolpidem; Zolpidem tartrate2件: Zolpidem tartrate ,
Zolpidem 💬 		16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 5, 6, 46 💬