Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Aficamten
(N-- 1-methyl-1h-pyrazole-4-carboxamide)		1件: Aficamten1件: Aficamten 💬 5件: MYH6_7,
MYH6_7,
MYL2,
MYL3,
MYL4 💬 		17件: Adherens junction, Adrenergic signaling in cardiomyocytes, Apelin signaling pathway, Cardiac muscle contraction, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy, Leukocyte transendothelial migration, Motor proteins, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Viral myocarditis, cGMP-PKG signaling pathway 💬1件: 58 💬
2 Allopurinol
(1H-Pyrazolopyrimidin-4-ol)		2件: Allopurinol; Allopurinol sodium2件: Allopurinol ,
Allopurinol sodium 💬 		1件: XDH 💬 4件: Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬7件: 6, 46, 57, 60, 66, 96, 97 💬
3 Berotralstat
(1H-pyrazole-5-carboxamide dihydrochloride)		2件: BCX7353; Berotralstat2件: Berotralstat ,
Berotralstat hydrochloride 💬 		1件: KLKB1 💬 1件: Complement and coagulation cascades 💬1件: 65 💬
4 MG-S-2525
(5--1H-pyrazole-4-carboxylic acid amide)		1件: MG-S-2525---1件: 85 💬
5 Pirtobrutinib
(1h-pyrazole-4-carboxamide)		1件: Pirtobrutinib1件: Pirtobrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬1件: 13 💬
6 Pyrazole
(1H-Pyrazol)		2件: 1H-pyrazol; Pyrazole---3件: 2, 58, 75 💬