Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abacavir 💬1件: Abacavir2件: Abacavir; Abacavir sulfate--5件: 2, 49, 135, 265, 325 💬
2 Abacavir sulfate 💬1件: Abacavir2件: Abacavir; Abacavir sulfate--5件: 2, 49, 135, 265, 325 💬
3 Acipimox 💬1件: Acipimox1件: Acipimox--2件: 78, 265 💬
4 Amprenavir 💬1件: Amprenavir1件: Amprenavir--1件: 265 💬
5 Atazanavir 💬1件: Atazanavir1件: Atazanavir--1件: 265 💬
6 Atazanavir sulfate 💬1件: Atazanavir1件: Atazanavir--1件: 265 💬
7 Atorvastatin 💬1件: Atorvastatin3件: ATORVASTATIN; Atorvastatin Calcium; Atorvastatina1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬21件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
8 Atorvastatin calcium 💬1件: Atorvastatin3件: Atorvastatin; Atorvastatin Calcium; Atorvastatina1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬21件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
9 Baricitinib 💬1件: Baricitinib1件: Baricitinib2件: JAK1,
JAK2 💬 		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬24件: 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
10 Caffeine 💬1件: Caffeine1件: Caffeine11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
11 Caffeine citrate 💬1件: Caffeine1件: Caffeine11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
12 Cholic acid 💬1件: Cholic Acid1件: Cholic Acid1件: NR1H4 💬 1件: Bile secretion 💬4件: 20, 234, 265, 310 💬
13 Coptis rhizome 💬1件: Berberine2件: Berberine; Berberine Chloride--3件: 46, 97, 265 💬
14 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
15 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
16 Didanosine 💬1件: Didanosine1件: Didanosine--2件: 25, 265 💬
17 Diosmin 💬1件: Diosmin1件: Diosmin--4件: 46, 51, 97, 265 💬
18 Dolutegravir 💬1件: Dolutegravir1件: Dolutegravir--3件: 2, 26, 265 💬
19 Dolutegravir sodium 💬1件: Dolutegravir1件: Dolutegravir--3件: 2, 26, 265 💬
20 Doravirine 💬1件: Doravirine1件: Doravirine--1件: 265 💬
21 Efavirenz 💬1件: Efavirenz1件: Efavirenz--3件: 23, 67, 265 💬
22 Emtricitabine 💬1件: Emtricitabine1件: Emtricitabine--5件: 13, 25, 93, 265, 325 💬
23 Enfuvirtide 💬1件: Enfuvirtide1件: Enfuvirtide--2件: 25, 265 💬
24 Fenofibrate 💬1件: Fenofibrate1件: Fenofibrate1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265 💬
25 Indinavir 💬1件: Indinavir1件: Indinavir--1件: 265 💬
26 Indinavir sulfate 💬1件: Indinavir1件: Indinavir--1件: 265 💬
27 Indinavir sulfate ethanolate 💬1件: Indinavir1件: Indinavir--1件: 265 💬
28 Lactic acid 💬1件: Lactic acid1件: Lactic acid--3件: 46, 265, 299 💬
29 Lamivudine 💬1件: Lamivudine1件: Lamivudine--10件: 2, 26, 42, 46, 49, 135, 156, 223, 265, 325 💬
30 Lopinavir 💬1件: Lopinavir1件: Lopinavir--1件: 265 💬
31 Mecasermin 💬1件: Mecasermin1件: Mecasermin2件: GHR,
IGF1R 💬 		34件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cadherin signaling, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Hormone signaling, Integrin signaling, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬4件: 96, 168, 265, 299 💬
32 Mecasermin rinfabate 💬1件: Mecasermin1件: Mecasermin2件: GHR,
IGF1R 💬 		34件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cadherin signaling, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Hormone signaling, Integrin signaling, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬4件: 96, 168, 265, 299 💬
33 Melatonin 💬1件: Melatonin1件: Melatonin2件: MTNR1A,
MTNR1B 💬 		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
34 Metformin 💬1件: Metformin4件: Metformin; Metformin Hydrochloride; METFORMINA; Metformine2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
35 Metformin hydrochloride 💬1件: Metformin4件: Metformin; METFORMIN HYDROCHLORIDE; METFORMINA; Metformine2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
36 Metreleptin 💬1件: Metreleptin2件: METRELEPTIN; R-metHuLeptin1件: LEPR 💬 7件: AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬1件: 265 💬
37 Nelfinavir 💬1件: Nelfinavir2件: Nelfinavir; Nelfinavir mesylate--3件: 49, 265, 331 💬
38 Nelfinavir mesylate 💬1件: Nelfinavir2件: Nelfinavir; Nelfinavir mesylate--3件: 49, 265, 331 💬
39 Nevirapine 💬1件: Nevirapine1件: Nevirapine--1件: 265 💬
40 Niacin 💬1件: Niacin2件: Niacin; Nicotinic acid--4件: 6, 46, 79, 265 💬
41 Obeticholic acid 💬1件: Obeticholic acid1件: Obeticholic Acid1件: NR1H4 💬 1件: Bile secretion 💬3件: 93, 265, 296 💬
42 Pegvisomant 💬1件: Pegvisomant1件: PEGVISOMANT1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 77, 265 💬
43 Pioglitazone 💬1件: Pioglitazone1件: Pioglitazone1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
44 Pioglitazone hydrochloride 💬1件: Pioglitazone1件: Pioglitazone1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
45 Pravastatin 💬1件: Pravastatin2件: Pravastatin; Pravastatin sodium1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬11件: 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
46 Pravastatin sodium 💬1件: Pravastatin2件: Pravastatin; Pravastatin sodium1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬11件: 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
47 Raltegravir 💬1件: Raltegravir1件: Raltegravir--4件: 13, 26, 93, 265 💬
48 Raltegravir potassium 💬1件: Raltegravir1件: Raltegravir--4件: 13, 26, 93, 265 💬
49 Riboflavin 💬1件: Riboflavin2件: Riboflavin; Vitamin B2--8件: 13, 38, 46, 96, 97, 162, 168, 265 💬
50 Ritonavir 💬1件: Ritonavir1件: Ritonavir--3件: 2, 86, 265 💬
51 Rosiglitazone 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬7件: 46, 57, 75, 77, 97, 222, 265 💬
52 Rosiglitazone maleate 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬7件: 46, 57, 75, 77, 97, 222, 265 💬
53 Saquinavir 💬1件: Saquinavir1件: Saquinavir--4件: 86, 222, 223, 265 💬
54 Saquinavir mesylate 💬1件: Saquinavir1件: Saquinavir--4件: 86, 222, 223, 265 💬
55 Setmelanotide 💬1件: Setmelanotide1件: Setmelanotide1件: MC4R 💬 3件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬5件: 134, 193, 202, 236, 265 💬
56 Setmelanotide acetate 💬1件: Setmelanotide1件: Setmelanotide1件: MC4R 💬 3件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬5件: 134, 193, 202, 236, 265 💬
57 Simvastatin 💬1件: Simvastatin2件: Simvastatin; Simvastatine1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬22件: 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
58 Sodium lactate 💬1件: Lactic acid1件: Lactic acid--3件: 46, 265, 299 💬
59 Stavudine 💬1件: Stavudine1件: Stavudine--1件: 265 💬
60 Tenofovir 💬1件: Tenofovir1件: Tenofovir--8件: 2, 6, 13, 25, 26, 93, 265, 325 💬
61 Tenofovir disoproxil fumarate 💬1件: Tenofovir disoproxil2件: Tenofovir disoproxil; Tenofovir Disoproxil Fumarate--3件: 6, 93, 265 💬
62 Tenofovir disoproxil maleate 💬1件: Tenofovir disoproxil2件: Tenofovir disoproxil; Tenofovir Disoproxil Fumarate--3件: 6, 93, 265 💬
63 Tenofovir disoproxil phosphate 💬1件: Tenofovir disoproxil2件: Tenofovir disoproxil; Tenofovir Disoproxil Fumarate--3件: 6, 93, 265 💬
64 Tesamorelin 💬1件: Tesamorelin1件: Tesamorelin1件: GHRHR 💬 3件: Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬1件: 265 💬
65 Tesamorelin acetate 💬1件: Tesamorelin1件: Tesamorelin1件: GHRHR 💬 3件: Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬1件: 265 💬
66 Testosterone 💬1件: Testosterone1件: Testosterone1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
67 Thiamine 💬1件: Thiamine1件: Thiamine--5件: 8, 13, 93, 265, 340 💬
68 Thiamine hydrochloride 💬1件: Thiamine1件: Thiamine--5件: 8, 13, 93, 265, 340 💬
69 Thiamine mononitrate 💬1件: Thiamine1件: Thiamine--5件: 8, 13, 93, 265, 340 💬
70 Tipranavir 💬1件: Tipranavir1件: Tipranavir--1件: 265 💬
71 Tipranavir disodium 💬1件: Tipranavir1件: Tipranavir--1件: 265 💬
72 Tirzepatide 💬1件: Tirzepatide1件: Tirzepatide2件: GIPR,
GLP1R 💬 		4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 67, 96, 97, 193, 233, 265 💬
73 Volanesorsen 💬1件: Volanesorsen1件: Volanesorsen1件: APOC3 💬 2件: Cholesterol metabolism, PPAR signaling pathway 💬1件: 265 💬
74 Volanesorsen sodium 💬1件: Volanesorsen1件: Volanesorsen1件: APOC3 💬 2件: Cholesterol metabolism, PPAR signaling pathway 💬1件: 265 💬
75 Zidovudine 💬1件: Zidovudine1件: Zidovudine--6件: 25, 26, 135, 265, 325, 331 💬