Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abacavir 2件: Abacavir; Abacavir sulfate2件: Abacavir sulfate ,
Abacavir 💬 		--5件: 2, 49, 135, 265, 325 💬
2 Acetate 1件: Acetate---52件: 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
3 Acetylcarnitine 2件: Acetyl-l-carnitine; Acetylcarnitine---3件: 2, 97, 265 💬
4 Acipimox 1件: Acipimox1件: Acipimox 💬 --2件: 78, 265 💬
5 Amprenavir 1件: Amprenavir1件: Amprenavir 💬 --1件: 265 💬
6 Aramchol 1件: Aramchol---2件: 94, 265 💬
7 Atazanavir 1件: Atazanavir2件: Atazanavir sulfate ,
Atazanavir 💬 		--1件: 265 💬
8 Atorvastatin 3件: Atorvastatin; Atorvastatin Calcium; Atorvastatina2件: Atorvastatin calcium ,
Atorvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬21件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
9 Baricitinib 1件: Baricitinib1件: Baricitinib 💬 2件: JAK1,
JAK2 💬 		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬24件: 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
10 Berberine 2件: Berberine; Berberine Chloride1件: Coptis rhizome 💬 --3件: 46, 97, 265 💬
11 Caffeine 1件: Caffeine2件: Caffeine ,
Caffeine citrate 💬 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
12 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
13 Cholic Acid 1件: Cholic Acid1件: Cholic acid 💬 1件: NR1H4 💬 1件: Bile secretion 💬4件: 20, 234, 265, 310 💬
14 Cyclophosphamide 5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
15 Didanosine 1件: Didanosine1件: Didanosine 💬 --2件: 25, 265 💬
16 Diosmin 1件: Diosmin1件: Diosmin 💬 --4件: 46, 51, 97, 265 💬
17 Dolutegravir 1件: Dolutegravir2件: Dolutegravir ,
Dolutegravir sodium 💬 		--3件: 2, 26, 265 💬
18 Doravirine 1件: Doravirine1件: Doravirine 💬 --1件: 265 💬
19 Efavirenz 1件: Efavirenz1件: Efavirenz 💬 --3件: 23, 67, 265 💬
20 Emtricitabine 1件: Emtricitabine1件: Emtricitabine 💬 --5件: 13, 25, 93, 265, 325 💬
21 Enfuvirtide 1件: Enfuvirtide1件: Enfuvirtide 💬 --2件: 25, 265 💬
22 Fenofibrate 1件: Fenofibrate1件: Fenofibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265 💬
23 Gemcabene 1件: Gemcabene---2件: 79, 265 💬
24 Indinavir 1件: Indinavir3件: Indinavir sulfate ,
Indinavir sulfate ethanolate ,
Indinavir 💬 		--1件: 265 💬
25 L-Lactic acid 2件: L-Lactic acid; Lactic acid---1件: 265 💬
26 Lactic acid 1件: Lactic acid2件: Lactic acid ,
Sodium lactate 💬 		--3件: 46, 265, 299 💬
27 Lamivudine 1件: Lamivudine1件: Lamivudine 💬 --10件: 2, 26, 42, 46, 49, 135, 156, 223, 265, 325 💬
28 Leptin 1件: Leptin---2件: 6, 265 💬
29 Lopinavir 1件: Lopinavir1件: Lopinavir 💬 --1件: 265 💬
30 Mecasermin 1件: Mecasermin2件: Mecasermin ,
Mecasermin rinfabate 💬 		2件: GHR,
IGF1R 💬 		34件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cadherin signaling, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Hormone signaling, Integrin signaling, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬4件: 96, 168, 265, 299 💬
31 Melatonin 1件: MELATONIN1件: Melatonin 💬 2件: MTNR1A,
MTNR1B 💬 		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
32 Metformin 4件: Metformin; Metformin Hydrochloride; METFORMINA; Metformine2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
33 Metreleptin 2件: METRELEPTIN; R-metHuLeptin1件: Metreleptin 💬 1件: LEPR 💬 7件: AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬1件: 265 💬
34 Mibavademab 1件: Mibavademab---1件: 265 💬
35 Nelfinavir 2件: Nelfinavir; Nelfinavir mesylate2件: Nelfinavir mesylate ,
Nelfinavir 💬 		--3件: 49, 265, 331 💬
36 Nevirapine 1件: Nevirapine1件: Nevirapine 💬 --1件: 265 💬
37 Niacin 2件: Niacin; Nicotinic acid1件: Niacin 💬 --4件: 6, 46, 79, 265 💬
38 Obeticholic acid 1件: Obeticholic Acid1件: Obeticholic acid 💬 1件: NR1H4 💬 1件: Bile secretion 💬3件: 93, 265, 296 💬
39 Pegvisomant 1件: Pegvisomant1件: Pegvisomant 💬 1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 77, 265 💬
40 Pioglitazone 1件: Pioglitazone2件: Pioglitazone hydrochloride ,
Pioglitazone 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
41 Pravastatin 2件: Pravastatin; Pravastatin sodium2件: Pravastatin sodium ,
Pravastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬11件: 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
42 Raltegravir 1件: Raltegravir2件: Raltegravir ,
Raltegravir potassium 💬 		--4件: 13, 26, 93, 265 💬
43 Riboflavin 2件: RIBOFLAVIN; Vitamin B21件: Riboflavin 💬 --8件: 13, 38, 46, 96, 97, 162, 168, 265 💬
44 Ritonavir 1件: Ritonavir1件: Ritonavir 💬 --3件: 2, 86, 265 💬
45 Rosiglitazone 2件: Rosiglitazone; Rosiglitazone maleate2件: Rosiglitazone maleate ,
Rosiglitazone 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬7件: 46, 57, 75, 77, 97, 222, 265 💬
46 Saquinavir 1件: Saquinavir2件: Saquinavir ,
Saquinavir mesylate 💬 		--4件: 86, 222, 223, 265 💬
47 Setmelanotide 1件: Setmelanotide2件: Setmelanotide ,
Setmelanotide acetate 💬 		1件: MC4R 💬 3件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬5件: 134, 193, 202, 236, 265 💬
48 Simvastatin 2件: Simvastatin; Simvastatine1件: Simvastatin 💬 1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬22件: 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
49 Stavudine 1件: Stavudine1件: Stavudine 💬 --1件: 265 💬
50 Tenofovir 1件: Tenofovir1件: Tenofovir 💬 --8件: 2, 6, 13, 25, 26, 93, 265, 325 💬
51 Tenofovir disoproxil 2件: Tenofovir disoproxil; Tenofovir Disoproxil Fumarate3件: Tenofovir disoproxil fumarate ,
Tenofovir disoproxil phosphate ,
Tenofovir disoproxil maleate 💬 		--3件: 6, 93, 265 💬
52 Tesamorelin 1件: Tesamorelin2件: Tesamorelin ,
Tesamorelin acetate 💬 		1件: GHRHR 💬 3件: Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬1件: 265 💬
53 Testosterone 1件: Testosterone1件: Testosterone 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
54 Thiamine 1件: Thiamine3件: Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--5件: 8, 13, 93, 265, 340 💬
55 Tipranavir 1件: Tipranavir2件: Tipranavir disodium ,
Tipranavir 💬 		--1件: 265 💬
56 Tirzepatide 1件: Tirzepatide1件: Tirzepatide 💬 2件: GIPR,
GLP1R 💬 		4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 67, 96, 97, 193, 233, 265 💬
57 Volanesorsen 1件: Volanesorsen2件: Volanesorsen ,
Volanesorsen sodium 💬 		1件: APOC3 💬 2件: Cholesterol metabolism, PPAR signaling pathway 💬1件: 265 💬
58 Zidovudine 1件: Zidovudine1件: Zidovudine 💬 --6件: 25, 26, 135, 265, 325, 331 💬