Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 💬1件: Abatacept1件: ABATACEPT2件: CD80,
CD86 💬 		14件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬28件: 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Alefacept 💬1件: Alefacept1件: Alefacept1件: CD58 💬 2件: Cell adhesion molecule (CAM) interaction, Epstein-Barr virus infection 💬6件: 37, 60, 65, 164, 284, 285 💬
3 Alemtuzumab 💬1件: Alemtuzumab1件: Alemtuzumab--21件: 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
4 Bitopertin 💬1件: Bitopertin1件: Bitopertin1件: SLC6A9 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle 💬2件: 254, 284 💬
5 Busulfan 💬1件: Busulfan2件: Busulfan; BUSULFANO--14件: 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
6 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; CYCLOPHOSPHAMIDE; CYCLOPHOSPHAMIDE MONOHYDRATE--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
7 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
8 Cyclosporine 💬1件: Cyclosporine7件: CICLOSPORIN; Ciclosporina; Ciclosporine; CYCLOSPORIN; Cyclosporin A; Cyclosporine; Cyclosporine A5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
9 Daclizumab 💬1件: Daclizumab1件: Daclizumab1件: IL2RA 💬 11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬10件: 13, 26, 56, 60, 63, 65, 97, 107, 283, 284 💬
10 Deferasirox 💬1件: Deferasirox1件: Deferasirox--5件: 54, 60, 254, 284, 286 💬
11 Deferitazole 💬1件: Deferitazole1件: Deferitazole--1件: 284 💬
12 Deferoxamine 💬1件: Deferoxamine1件: Deferoxamine--2件: 284, 286 💬
13 Deferoxamine hydrochloride 💬1件: Deferoxamine1件: Deferoxamine--2件: 284, 286 💬
14 Deferoxamine mesylate 💬1件: Deferoxamine1件: Deferoxamine--2件: 284, 286 💬
15 Eltrombopag choline 💬1件: Eltrombopag2件: Eltrombopag; ELTROMBOPAG OLAMINE1件: MPL 💬 3件: Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬5件: 60, 63, 65, 284, 285 💬
16 Eltrombopag olamine 💬1件: Eltrombopag2件: Eltrombopag; ELTROMBOPAG OLAMINE1件: MPL 💬 3件: Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬5件: 60, 63, 65, 284, 285 💬
17 Ferrous fumarate 💬1件: Iron1件: Iron--7件: 18, 60, 96, 97, 238, 254, 284 💬
18 Filgrastim 💬1件: Filgrastim4件: Filgrastim; G-CSF; Gcsf; Granulocyte Colony Stimulating Factor1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬30件: 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
19 Fludarabine 💬1件: Fludarabine3件: FLUDARABINA; Fludarabine; Fludarabine Phosphate1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
20 Fludarabine phosphate 💬1件: Fludarabine3件: FLUDARABINA; Fludarabine; Fludarabine phosphate1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
21 Hydroxyurea 💬1件: Hydroxyurea1件: Hydroxyurea1件: RRM2 💬 5件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
22 Lenalidomide 💬1件: Lenalidomide1件: Lenalidomide1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬9件: 16, 26, 28, 34, 49, 56, 284, 300, 331 💬
23 Leucine 💬1件: Leucine2件: L-leucine; Leucine--13件: 5, 6, 7, 18, 19, 65, 96, 97, 127, 280, 283, 284, 299 💬
24 Magnesium hydroxide 💬1件: Magnesium hydroxide1件: Magnesium hydroxide--1件: 284 💬
25 Melphalan 💬1件: Melphalan2件: Melphalan; Melphalan Hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
26 Melphalan hydrochloride 💬1件: Melphalan2件: MELPHALAN; Melphalan Hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
27 Methotrexate 💬1件: Methotrexate5件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Methylaminopterin; Metotrexato2件: DHFR,
DHFR2 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
28 Methotrexate sodium 💬1件: Methotrexate5件: Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO2件: DHFR,
DHFR2 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
29 Methylprednisolone 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
30 Methylprednisolone acetate 💬1件: Methylprednisolone3件: Methylprednisolon; METHYLPREDNISOLONE; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
31 Mycophenolate mofetil 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
32 Mycophenolate mofetil hydrochloride 💬1件: Mycophenolate mofetil1件: Mycophenolate Mofetil2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
33 Prednisone 💬1件: Prednisone2件: Prednisona; Prednisone1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
34 Rimiducid 💬1件: Rimiducid1件: Rimiducid1件: CASP9 💬 34件: Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬7件: 19, 49, 60, 65, 284, 285, 326 💬
35 Rituximab 💬1件: Rituximab1件: RITUXIMAB1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
36 Rivogenlecleucel 💬1件: Rivogenlecleucel1件: Rivogenlecleucel--6件: 19, 60, 65, 284, 285, 326 💬
37 Sotatercept 💬1件: Sotatercept1件: Sotatercept1件: ACVR2A 💬 4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬2件: 86, 284 💬
38 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
39 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
40 Thiotepa 💬1件: Thiotepa1件: Thiotepa--14件: 13, 19, 20, 28, 46, 51, 60, 65, 85, 96, 107, 164, 284, 285 💬
41 Treosulfan 💬1件: Treosulfan1件: TREOSULFAN--6件: 13, 19, 62, 65, 284, 286 💬
42 Trifluoperazine 💬1件: Trifluoperazine1件: Trifluoperazine1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284 💬
43 Trifluoperazine hydrochloride 💬1件: Trifluoperazine1件: Trifluoperazine1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284 💬