Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 AKR1B 💬 [5] Pentose and glucuronate interconversions, Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Folate biosynthesis Epalrestat 💬 Epalrestat [1] 10 💬
2 GABBR 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
3 GABBR 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
4 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone hydrochloride 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
5 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
6 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone hydrochloride 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
7 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
8 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naltrexone 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
9 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naltrexone hydrochloride 💬 Naltrexone [12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
10 PGR 💬 [5] Oocyte meiosis, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Chemical carcinogenesis - receptor activation, Breast cancer Ulipristal acetate 💬 Ulipristal [1] 10 💬
11 PGR 💬 [5] Oocyte meiosis, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Chemical carcinogenesis - receptor activation, Breast cancer Ulipristal 💬 Ulipristal [1] 10 💬
12 SCN1A 💬 [1] Dopaminergic synapse Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
13 SCN1A 💬 [1] Dopaminergic synapse Mexiletine hydrochloride 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
14 SCN2A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
15 SCN2A 💬 [1] Taste transduction Mexiletine hydrochloride 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
16 SCN3A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
17 SCN3A 💬 [1] Taste transduction Mexiletine hydrochloride 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
18 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Mexiletine hydrochloride 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
19 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
20 SCN9A 💬 [1] Taste transduction Mexiletine hydrochloride 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
21 SCN9A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬