Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Lansoprazole 💬 Lansoprazole [8] 63, 71, 85, 98, 166, 222, 223, 299 💬
2 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Lansoprazole 💬 Lansoprazole [8] 63, 71, 85, 98, 166, 222, 223, 299 💬
3 F10 💬 [1] Complement and coagulation cascades Edoxaban tosilate hydrate 💬 Edoxaban [4] 46, 71, 88, 222 💬
4 F10 💬 [1] Complement and coagulation cascades Edoxaban tosylate 💬 Edoxaban [4] 46, 71, 88, 222 💬
5 F10 💬 [1] Complement and coagulation cascades Edoxaban 💬 Edoxaban [4] 46, 71, 88, 222 💬
6 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin magnesium 💬 Pitavastatin [4] 49, 71, 79, 90 💬
7 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin calcium 💬 Pitavastatin [4] 49, 71, 79, 90 💬
8 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
9 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone phosphate 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
10 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone sodium phosphate 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
11 P2RY12 💬 [3] Neuroactive ligand signaling, Efferocytosis, Platelet activation Clopidogrel besilate 💬 Clopidogrel [7] 40, 49, 51, 62, 71, 86, 222 💬
12 P2RY12 💬 [3] Neuroactive ligand signaling, Efferocytosis, Platelet activation Clopidogrel 💬 Clopidogrel [7] 40, 49, 51, 62, 71, 86, 222 💬
13 P2RY12 💬 [3] Neuroactive ligand signaling, Efferocytosis, Platelet activation Clopidogrel bisulfate 💬 Clopidogrel [7] 40, 49, 51, 62, 71, 86, 222 💬
14 P2RY12 💬 [3] Neuroactive ligand signaling, Efferocytosis, Platelet activation Clopidogrel hydrochloride 💬 Clopidogrel [7] 40, 49, 51, 62, 71, 86, 222 💬
15 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Valdecoxib 💬 Parecoxib [3] 46, 71, 271 💬
16 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Parecoxib 💬 Parecoxib [3] 46, 71, 271 💬
17 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Parecoxib sodium 💬 Parecoxib [3] 46, 71, 271 💬
18 PTH1R 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption Teriparatide 💬 Teriparatide [7] 46, 68, 70, 71, 172, 235, 274 💬
19 PTH1R 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption Teriparatide acetate 💬 Teriparatide [7] 46, 68, 70, 71, 172, 235, 274 💬
20 PTH1R 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption Teriparatide acetate 💬 Teriparatide [7] 46, 68, 70, 71, 172, 235, 274 💬
21 SCN1A 💬 [1] Dopaminergic synapse Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
22 SCN1A 💬 [1] Dopaminergic synapse Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
23 SCN1A 💬 [1] Dopaminergic synapse Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
24 SCN1A 💬 [1] Dopaminergic synapse Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
25 SCN2A 💬 [1] Taste transduction Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
26 SCN2A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
27 SCN2A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
28 SCN2A 💬 [1] Taste transduction Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
29 SCN3A 💬 [1] Taste transduction Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
30 SCN3A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
31 SCN3A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
32 SCN3A 💬 [1] Taste transduction Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
33 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
34 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
35 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
36 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
37 SCN8A 💬 [1] IgSF CAM signaling Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
38 SCN8A 💬 [1] IgSF CAM signaling Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
39 SCN8A 💬 [1] IgSF CAM signaling Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
40 SCN8A 💬 [1] IgSF CAM signaling Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
41 SCN9A 💬 [1] Taste transduction Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
42 SCN9A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
43 SCN9A 💬 [1] Taste transduction Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
44 SCN9A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
45 SERPINC1 💬 [1] Complement and coagulation cascades Adomiparin 💬 Enoxaparin [6] 46, 48, 71, 222, 223, 327 💬
46 SERPINC1 💬 [1] Complement and coagulation cascades Enoxaparin sodium 💬 Enoxaparin [6] 46, 48, 71, 222, 223, 327 💬