Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 COMT 💬 [3] Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Tolcapone 💬 Tolcapone [3] 6, 28, 127 💬
2 COMT 💬 [3] Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Opicapone 💬 Opicapone [1] 6 💬
3 COMT 💬 [3] Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Entacapone 💬 Entacapone [2] 6, 17 💬
4 CYP11A 💬 [5] Steroid hormone biosynthesis, Ovarian steroidogenesis, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole [1] 75 💬
5 CYP11B1 💬 [3] Steroid hormone biosynthesis, Cortisol synthesis and secretion, Cushing syndrome Metyrapone 💬 Metyrapone [1] 75 💬
6 CYP11B1 💬 [3] Steroid hormone biosynthesis, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole [1] 75 💬
7 CYP11B2 💬 [2] Steroid hormone biosynthesis, Aldosterone synthesis and secretion Osilodrostat phosphate 💬 Osilodrostat [1] 75 💬
8 CYP11B2 💬 [2] Steroid hormone biosynthesis, Aldosterone synthesis and secretion Osilodrostat 💬 Osilodrostat [1] 75 💬
9 CYP17A 💬 [5] Steroid hormone biosynthesis, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Levoketoconazole 💬 Levoketoconazole [1] 75 💬
10 CYP17A 💬 [5] Steroid hormone biosynthesis, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome Abiraterone acetate 💬 Abiraterone [2] 75, 81 💬
11 CYP19A 💬 [2] Steroid hormone biosynthesis, Ovarian steroidogenesis Anastrozole 💬 Anastrozole [3] 78, 86, 193 💬
12 CYP19A 💬 [2] Steroid hormone biosynthesis, Ovarian steroidogenesis Letrozole 💬 Letrozole [2] 81, 89 💬
13 HSD11B1 💬 [3] Steroid hormone biosynthesis, Metabolism of xenobiotics by cytochrome P450, Chemical carcinogenesis - DNA adducts Dipotassium glycyrrhizinate 💬 Glycyrrhizic acid [2] 46, 51 💬
14 SRD5A1 💬 [1] Steroid hormone biosynthesis Dutasteride 💬 Dutasteride [2] 1, 2 💬
15 SRD5A2 💬 [2] Steroid hormone biosynthesis, Prostate cancer Finasteride 💬 Finasteride [1] 6 💬
16 SRD5A2 💬 [2] Steroid hormone biosynthesis, Prostate cancer Dutasteride 💬 Dutasteride [2] 1, 2 💬