Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetylcysteine 4件: Acetylcysteine; N acetyl cysteine; N-Acetyl cysteine; N-Acetylcysteine1件: Acetylcysteine 💬 --25件: 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
2 Alemtuzumab 1件: Alemtuzumab1件: Alemtuzumab 💬 --21件: 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
3 Bezafibrate 1件: Bezafibrate1件: Bezafibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
4 Biotin 4件: Biotin; Biotina; D-BIOTIN; Vitamin B71件: Biotin 💬 --6件: 2, 8, 10, 13, 14, 20 💬
5 Busulfan 2件: Busulfan; BUSULFANO1件: Busulfan 💬 --14件: 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
6 Chenodeoxycholic acid 2件: Chenodeoxycholic acid; Chenodiol1件: Chenodiol 💬 1件: NR1H4 💬 1件: Bile secretion 💬5件: 20, 86, 96, 234, 263 💬
7 Cholic Acid 1件: Cholic Acid1件: Cholic acid 💬 1件: NR1H4 💬 1件: Bile secretion 💬4件: 20, 234, 265, 310 💬
8 Clofarabine 1件: Clofarabine1件: Clofarabine 💬 3件: POLA1,
POLA2,
RRM1 💬 		5件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
9 Cyclophosphamide 5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
10 Cyclosporine 7件: CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A1件: Cyclosporine 💬 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
11 Dimethyl fumarate 1件: Dimethyl fumarate1件: Dimethyl fumarate 💬 1件: KEAP1 💬 6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 20, 51, 86, 296 💬
12 Elivaldogene autotemcel 1件: Elivaldogene autotemcel1件: Elivaldogene autotemcel 💬 1件: ABCD1 💬 2件: ABC transporters, Peroxisome 💬1件: 20 💬
13 Glyceryl Trierucate 1件: Glyceryl Trierucate---1件: 20 💬
14 Glyceryl Trioleate 1件: Glyceryl Trioleate---1件: 20 💬
15 Hydroxyurea 1件: Hydroxyurea1件: Hydroxyurea 💬 1件: RRM2 💬 5件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
16 Leriglitazone 1件: Leriglitazone1件: Leriglitazone 💬 1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 20 💬
17 Lipoic acid 3件: Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid1件: Thioctic acid 💬 --6件: 2, 5, 13, 14, 20, 97 💬
18 Melphalan 2件: Melphalan; Melphalan Hydrochloride2件: Melphalan ,
Melphalan hydrochloride 💬 		--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
19 Mycophenolate mofetil 1件: Mycophenolate Mofetil2件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
20 Pioglitazone 1件: Pioglitazone2件: Pioglitazone hydrochloride ,
Pioglitazone 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
21 Plerixafor 1件: Plerixafor1件: Plerixafor 💬 1件: CXCR4 💬 14件: Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬5件: 20, 51, 65, 285, 299 💬
22 Pramipexole 3件: Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE2件: Pramipexole dihydrochloride ,
Pramipexole 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 2, 6, 20, 74 💬
23 PXL-770 free acid anhydrous 0件: ---1件: 20 💬
24 SBT101 1件: SBT101---1件: 20 💬
25 Sobetirome 1件: Sobetirome1件: Sobetirome 💬 1件: THRB 💬 3件: Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20 💬
26 Thalidomide 1件: Thalidomide1件: Thalidomide 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬22件: 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
27 Thiotepa 1件: Thiotepa1件: Thiotepa 💬 --14件: 13, 19, 20, 28, 46, 51, 60, 65, 85, 96, 107, 164, 284, 285 💬
28 Vitamin E 1件: Vitamin E1件: Vitamin E 💬 --12件: 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
29 VK-0214 1件: VK0214---1件: 20 💬