Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetate 1件: Acetate---52件: 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
2 Acetazolamide 1件: Acetazolamide2件: Acetazolamide ,
Acetazolamide sodium 💬 		13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		6件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
3 Acetylcysteine 4件: Acetylcysteine; N acetyl cysteine; N-acetyl cysteine; N-acetylcysteine1件: Acetylcysteine 💬 --25件: 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
4 Acetylcysteine amide 2件: Acetylcysteine amide; N-acetylcysteine amide---3件: 19, 90, 303 💬
5 Adalimumab 1件: ADALIMUMAB1件: Adalimumab 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬22件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
6 Aflibercept 1件: Aflibercept1件: Aflibercept 💬 3件: PGF,
VEGFA,
VEGFB 💬 		24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 90, 166 💬
7 Amino acids 1件: Amino acids---6件: 6, 70, 90, 113, 240, 298 💬
8 Betamethasone 1件: Betamethasone6件: Betamethasone ,
Betamethasone sodium phosphate ,
Betamethasone valerate ,
Betamethasone acetate ,
Betamethasone dipropionate ,
Betamethasone benzoate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
9 Botaretigene sparoparvovec 1件: Botaretigene Sparoparvovec---1件: 90 💬
10 Brimonidine 2件: Brimonidine; Brimonidine Tartrate2件: Brimonidine tartrate ,
Brimonidine 💬 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 13, 90 💬
11 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
12 Carbidopa 1件: CARBIDOPA1件: Carbidopa 💬 1件: DDC 💬 8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201 💬
13 Cholesterol 1件: Cholesterol1件: Cholesterol 💬 --10件: 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
14 Cotoretigene toliparvovec 3件: AAV8-RPGR; BIIB112; Cotoretigene Toliparvovec---1件: 90 💬
15 Cyclosporine 7件: CICLOSPORIN; Ciclosporina; Ciclosporine; CYCLOSPORIN; Cyclosporin A; Cyclosporine; Cyclosporine A1件: Cyclosporine 💬 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
16 Cysteine 2件: Cysteine; Cysteine hydrochloride2件: L-Cysteine ,
Cysteine hydrochloride 💬 		--13件: 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
17 Dexamethasone 4件: Dexametasone; Dexamethason; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE3件: Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
18 Disulfiram 1件: Disulfiram1件: Disulfiram 💬 3件: ALDH1B1,
ALDH2,
ALDH3A2 💬 		13件: Alcoholic liver disease, Arginine and proline metabolism, Ascorbate and aldarate metabolism, Fatty acid degradation, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Lysine degradation, Pantothenate and CoA biosynthesis, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬3件: 46, 90, 301 💬
19 Dorzolamide 1件: Dorzolamide2件: Dorzolamide hydrochloride ,
Dorzolamide 💬 		13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		6件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90 💬
20 EA-2353 1件: EA-2353---1件: 90 💬
21 Fluocinolone 1件: Fluocinolone---1件: 90 💬
22 Fluocinolone acetonide 1件: Fluocinolone Acetonide1件: Fluocinolone acetonide 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 90 💬
23 Ginkgo biloba 1件: Ginkgo biloba1件: Ginkgo 💬 --4件: 13, 18, 47, 90 💬
24 GS030-DP 1件: GS030-DP---1件: 90 💬
25 Hydroxychloroquine 2件: HYDROXYCHLOROQUINE; HYDROXYCHLOROQUINE SULFATE2件: Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--29件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
26 KIO-301 1件: KIO-301---1件: 90 💬
27 Levodopa 2件: L-DOPA; Levodopa1件: Levodopa 💬 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬8件: 5, 6, 17, 90, 120, 140, 164, 201 💬
28 Lutein 1件: Lutein---3件: 13, 90, 164 💬
29 Melatonin 1件: Melatonin1件: Melatonin 💬 2件: MTNR1A,
MTNR1B 💬 		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
30 Minocycline 2件: Minocycline; MINOCYCLINE HYDROCHLORIDE2件: Minocycline hydrochloride ,
Minocycline 💬 		--14件: 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
31 Nerve Growth Factor 1件: Nerve Growth Factor---5件: 2, 3, 18, 53, 90 💬
32 Nilvadipine 1件: Nilvadipine1件: Nilvadipine 💬 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 90 💬
33 OCU400 1件: OCU400---1件: 90 💬
34 Omeprazole 3件: Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM3件: Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
35 Oxygen 1件: Oxygen1件: Oxygen 💬 --30件: 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
36 Pitavastatin 2件: Pitavastatin; PITAVASTATIN CALCIUM2件: Pitavastatin calcium ,
Pitavastatin magnesium 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬4件: 49, 71, 79, 90 💬
37 Platelet Rich Plasma 1件: Platelet Rich Plasma---6件: 35, 46, 47, 70, 90, 269 💬
38 Prednisone 2件: PREDNISONA; Prednisone1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
39 QR-1123 1件: QR-1123---1件: 90 💬
40 SAR421869 1件: SAR421869---2件: 90, 303 💬
41 Sildenafil 3件: SILDENAFIL; Sildenafil Citrate; SILDENAFILO2件: Sildenafil citrate ,
Sildenafil 💬 		1件: PDE5A 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
42 Timrepigene emparvovec 1件: Timrepigene emparvovec---1件: 90 💬
43 Triamcinolone 3件: TRIAMCINOLONE; Triamcinolone Acetonide; Triamcinolone hexacetonide4件: Triamcinolone ,
Triamcinolone acetonide ,
Triamcinolone diacetate ,
Triamcinolone hexacetonide 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
44 Ultevursen 1件: Ultevursen---2件: 90, 303 💬
45 Unoprostone 1件: Unoprostone2件: Isopropyl unoprostone ,
Unoprostone 💬 		1件: PTGFR 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 90 💬
46 Valproic acid 3件: Divalproex sodium; VALPROATE SODIUM; Valproic Acid3件: Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
47 Vitamin A 1件: Vitamin A2件: Vitamin A oil ,
Vitamin A 💬 		2件: RARA,
RARB 💬 		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬4件: 13, 53, 90, 97 💬
48 Vitamin E 1件: Vitamin E1件: Vitamin E 💬 --12件: 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
49 Zuretinol acetate 1件: Zuretinol Acetate---1件: 90 💬