Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 1件: ABATACEPT1件: Abatacept 💬 2件: CD80,
CD86 💬 		14件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬28件: 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Alkaline Phosphatase 1件: Alkaline Phosphatase---4件: 46, 93, 97, 172 💬
3 Atorvastatin 3件: ATORVASTATIN; Atorvastatin Calcium; Atorvastatina2件: Atorvastatin calcium ,
Atorvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬21件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
4 Azathioprine 2件: AZATHIOPRINE; Azatioprina2件: Azathioprine ,
Azathioprine sodium 💬 		--26件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
5 Baricitinib 1件: Baricitinib1件: Baricitinib 💬 2件: JAK1,
JAK2 💬 		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬24件: 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
6 Bezafibrate 1件: BEZAFIBRATE1件: Bezafibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
7 Budesonide 1件: BUDESONIDE1件: Budesonide 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬10件: 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
8 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
9 Choline 2件: Choline; Choline Chloride1件: Choline 💬 --4件: 93, 171, 193, 299 💬
10 Cilofexor 1件: Cilofexor---2件: 93, 94 💬
11 Colchicine 2件: COLCHICINA; Colchicine1件: Colchicine 💬 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬 		12件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, IgSF CAM signaling, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagocytosis, Prion disease, Salmonella infection 💬9件: 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
12 Cyclophosphamide 5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
13 Denosumab 1件: Denosumab1件: Denosumab 💬 1件: TNFSF11 💬 8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬11件: 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬
14 Elafibranor 1件: Elafibranor1件: Elafibranor 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94 💬
15 Emtricitabine 1件: Emtricitabine1件: Emtricitabine 💬 --5件: 13, 25, 93, 265, 325 💬
16 Ezetimibe 1件: Ezetimibe1件: Ezetimibe 💬 1件: NPC1L1 💬 1件: Fat digestion and absorption 💬5件: 49, 79, 93, 149, 260 💬
17 Fecal microbiota 3件: Fecal Microbial Transplantation; Fecal microbiota; Fecal microbiota transplantation---14件: 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 222, 271, 298 💬
18 Fenofibrate 1件: Fenofibrate1件: Fenofibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265 💬
19 Gold 1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
20 Golexanolone 1件: GOLEXANOLONE---1件: 93 💬
21 Hesperidin 1件: Hesperidin1件: Hesperidin 💬 --3件: 13, 46, 93 💬
22 Linerixibat 1件: Linerixibat1件: Linerixibat 💬 1件: SLC10A2 💬 1件: Bile secretion 💬1件: 93 💬
23 Magnesium 2件: MAGNESIO; Magnesium---23件: 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬
24 Methionine 2件: L-methionine; METHIONINE1件: Methionine 💬 --9件: 34, 75, 84, 93, 94, 229, 298, 300, 337 💬
25 Methotrexate 5件: Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO2件: Methotrexate ,
Methotrexate sodium 💬 		2件: DHFR,
DHFR2 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
26 Methylprednisolone 3件: Methylprednisolon; METHYLPREDNISOLONE; Methylprednisolone acetate2件: Methylprednisolone ,
Methylprednisolone acetate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
27 Minodronic acid 1件: Minodronic acid---4件: 6, 46, 93, 95 💬
28 Modafinil 1件: Modafinil1件: Modafinil 💬 --6件: 6, 13, 49, 93, 96, 97 💬
29 Moexipril 1件: Moexipril2件: Moexipril hydrochloride ,
Moexipril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 93 💬
30 Mycophenolate mofetil 1件: MYCOPHENOLATE MOFETIL2件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
31 Nalmefene 1件: Nalmefene3件: Nalmefene hydrochloride ,
Nalmefene ,
Nalmefene hydrochloride hydrate 💬 		3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 6, 93 💬
32 Obeticholic acid 1件: Obeticholic Acid1件: Obeticholic acid 💬 1件: NR1H4 💬 1件: Bile secretion 💬3件: 93, 265, 296 💬
33 Pemafibrate 1件: Pemafibrate1件: Pemafibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 67, 93 💬
34 Pentoxifylline 1件: Pentoxifylline1件: Pentoxifylline 💬 --13件: 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
35 Potassium 1件: Potassium1件: Potassium 💬 --17件: 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬
36 Prednisone 2件: Prednisona; Prednisone1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
37 Pyridoxine 2件: PYRIDOXINE; Vitamin B 62件: Pyridoxine hydrochloride ,
Pyridoxine 💬 		--5件: 49, 93, 145, 234, 320 💬
38 Raltegravir 1件: Raltegravir2件: Raltegravir ,
Raltegravir potassium 💬 		--4件: 13, 26, 93, 265 💬
39 Rifaximin 2件: Rifaximin; RIFAXIMINA1件: Rifaximin 💬 --8件: 6, 65, 93, 96, 97, 99, 296, 299 💬
40 Risedronic acid 3件: Risedronate; RISEDRONATE SODIUM; Risedronic acid3件: Risedronate sodium ,
Risedronic acid ,
Risedronate sodium monohydrate 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬7件: 46, 50, 93, 95, 107, 113, 274 💬
41 Rituximab 1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
42 Saroglitazar 2件: Saroglitazar; SAROGLITAZAR MAGNESIUM2件: Saroglitazar ,
Saroglitazar magnesium 💬 		3件: PPARA,
PPARD,
PPARG 💬 		22件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Efferocytosis, Glucagon signaling pathway, Hepatitis C, Huntington disease, Insulin resistance, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Wnt signaling pathway, cAMP signaling pathway 💬1件: 93 💬
43 Seladelpar 1件: SELADELPAR2件: Seladelpar ,
Seladelpar lysine 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94 💬
44 Setanaxib 1件: SETANAXIB---2件: 93, 218 💬
45 Tauroursodeoxycholic acid 3件: Tauroursodeoxycholic acid; Taurursodiol; Ursodoxicoltaurine1件: Taurursodiol 💬 --5件: 2, 28, 93, 299, 302 💬
46 Tenofovir 1件: Tenofovir1件: Tenofovir 💬 --8件: 2, 6, 13, 25, 26, 93, 265, 325 💬
47 Tenofovir disoproxil 2件: Tenofovir disoproxil; Tenofovir Disoproxil Fumarate3件: Tenofovir disoproxil fumarate ,
Tenofovir disoproxil phosphate ,
Tenofovir disoproxil maleate 💬 		--3件: 6, 93, 265 💬
48 Tetrathiomolybdate 1件: Tetrathiomolybdate---3件: 85, 93, 171 💬
49 Thiamine 1件: THIAMINE3件: Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--5件: 8, 13, 93, 265, 340 💬
50 Tigecycline 1件: Tigecycline1件: Tigecycline 💬 --2件: 93, 299 💬
51 Tropifexor 1件: Tropifexor1件: Tropifexor 💬 1件: NR1H4 💬 1件: Bile secretion 💬1件: 93 💬
52 Ursodeoxycholic acid 3件: UDCA; Ursodeoxycholic Acid; Ursodiol1件: Ursodiol 💬 1件: NR1H4 💬 1件: Bile secretion 💬10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
53 Ustekinumab 1件: Ustekinumab1件: Ustekinumab 💬 3件: IL12A,
IL12B,
IL23A 💬 		28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
54 Vitamin D 1件: Vitamin D---26件: 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
55 Volixibat 2件: Volixibat; Volixibat potassium2件: Volixibat potassium ,
Volixibat 💬 		--2件: 93, 94 💬
56 Zoledronic acid 2件: Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE5件: Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬