Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
2 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
3 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram 2件: 8, 13 💬
4 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
5 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate 1件: 226 💬
6 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
7 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
8 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
9 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Zatolmilast 💬 Zatolmilast 1件: 206 💬
10 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
11 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
12 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Dipyridamole 💬 Dipyridamole 5件: 46, 51, 66, 96, 224 💬
13 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast 2件: 2, 13 💬
14 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
15 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
16 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
17 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬
18 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
19 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate 1件: 226 💬
20 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
21 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
22 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline 1件: 63 💬
23 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate 1件: 226 💬
24 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast 4件: 84, 97, 206, 299 💬
25 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram 2件: 8, 13 💬
26 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬
27 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
28 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram 2件: 8, 13 💬
29 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast 4件: 84, 97, 206, 299 💬
30 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬
31 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
32 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
33 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
34 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast 2件: 2, 13 💬
35 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
36 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
37 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
38 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline 1件: 63 💬
39 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬
40 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
41 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast 2件: 2, 13 💬
42 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
43 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline 1件: 63 💬
44 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate 1件: 226 💬
45 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
46 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
47 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline 1件: 63 💬
48 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast 4件: 84, 97, 206, 299 💬
49 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬
50 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
51 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬
52 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
53 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
54 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬
55 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
56 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
57 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
58 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast 2件: 2, 13 💬
59 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast 4件: 84, 97, 206, 299 💬
60 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram 2件: 8, 13 💬
61 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine 8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
62 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline 2件: 236, 299 💬