Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetate 1件: Acetate---52件: 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
2 Albuterol 2件: Albuterol; Salbutamol2件: Albuterol sulfate ,
Albuterol 💬 		1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
3 Allogeneic Cardiosphere-Derived Cells 1件: Allogeneic Cardiosphere-Derived Cells---2件: 57, 113 💬
4 Amino acids 1件: Amino acids---6件: 6, 70, 90, 113, 240, 298 💬
5 Amlodipine 1件: AMLODIPINE4件: Amlodipine besylate ,
Amlodipine maleate ,
Amlodipine ,
Amlodipine benzoate 💬 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 51, 67, 79, 113, 222, 298 💬
6 AOC 1001 1件: AOC 10011件: Delpacibart 💬 1件: TFRC 💬 6件: Endocytosis, Ferroptosis, HIF-1 signaling pathway, Hematopoietic cell lineage, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬1件: 113 💬
7 AOC-1020 1件: AOC-1020---1件: 113 💬
8 Apitegromab 1件: Apitegromab1件: Apitegromab 💬 1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬2件: 3, 113 💬
9 Arginine 1件: Arginine3件: Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--16件: 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
10 ATA-100 1件: ATA-100---1件: 113 💬
11 Ataluren 1件: Ataluren1件: Ataluren 💬 --6件: 19, 113, 140, 246, 299, 329 💬
12 ATL1102 1件: ATL1102---2件: 13, 113 💬
13 ATX-01 1件: ATX-01---1件: 113 💬
14 ATYR-1940 1件: ATYR1940---1件: 113 💬
15 BB-301 1件: BB-301---1件: 113 💬
16 Bisoprolol 2件: BISOPROLOL; Bisoprolol Fumarate2件: Bisoprolol fumarate ,
Bisoprolol 💬 		1件: ADRB1 💬 13件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 57, 58, 67, 86, 113 💬
17 BLS-M22 1件: BLS-M22---1件: 113 💬
18 BMN-044 2件: BMN 044; PRO044---1件: 113 💬
19 BMN-045 2件: BMN 045; PRO045---1件: 113 💬
20 BMN-053 2件: BMN053; PRO053---1件: 113 💬
21 BMN-351 0件: ---1件: 113 💬
22 Bocidelpar 1件: Bocidelpar2件: Bocidelpar ,
Bocidelpar sulfate 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 113 💬
23 Botulinum toxin type A 5件: Botulinum toxin A; BOTULINUM TOXIN TYPE A; IncobotulinumtoxinA; Onabotulinumtoxin A; OnabotulinumtoxinA4件: Botulinum toxin type A ,
OnabotulinumtoxinA ,
AbobotulinumtoxinA ,
Incobotulinumtoxin A 💬 		1件: SNAP25 💬 2件: Insulin secretion, Synaptic vesicle cycle 💬13件: 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
24 Calcifediol 1件: Calcifediol1件: Calcifediol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 86, 113 💬
25 Canakinumab 1件: CANAKINUMAB1件: Canakinumab 💬 1件: IL1B 💬 43件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
26 Carvedilol 1件: Carvedilol2件: Carvedilol ,
Carvedilol phosphate 💬 		5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		15件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 6, 46, 57, 58, 86, 113, 210 💬
27 Casimersen 1件: CASIMERSEN1件: Casimersen 💬 1件: DMD 💬 5件: Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
28 Citrulline 2件: Citrulline; L-Citrulline2件: L-Citrulline ,
Citrulline malate 💬 		--3件: 21, 86, 113 💬
29 Clenbuterol 2件: Clenbuterol; CLENBUTEROL HYDROCHLORIDE2件: Clenbuterol hydrochloride ,
Clenbuterol 💬 		1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 1, 2, 6, 57, 113, 256 💬
30 Creatine 3件: Acetic acid; Creatine; Creatine monohydrate---18件: 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 97, 113, 156, 201, 256, 337 💬
31 Deflazacort 1件: DEFLAZACORT1件: Deflazacort 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬2件: 30, 113 💬
32 Delandistrogene moxeparvovec 1件: Delandistrogene moxeparvovec1件: Delandistrogene moxeparvovec 💬 1件: DMD 💬 5件: Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
33 Dexmedetomidine 4件: DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; Imidazole2件: Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
34 Drisapersen 1件: Drisapersen1件: Drisapersen 💬 1件: DMD 💬 5件: Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
35 DT-DEC01 1件: DT-DEC01---1件: 113 💬
36 DYNE-251 1件: DYNE-251---1件: 113 💬
37 Edasalonexent 1件: EDASALONEXENT1件: Edasalonexent 💬 1件: RELA 💬 76件: AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cadherin signaling, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬1件: 113 💬
38 Empagliflozin 1件: Empagliflozin1件: Empagliflozin 💬 --17件: 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
39 Enalapril 2件: Enalapril; Enalapril Maleate2件: Enalapril maleate ,
Enalapril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬10件: 13, 19, 46, 57, 66, 113, 210, 222, 223, 279 💬
40 ENTR-601-44 1件: ENTR-601-44---1件: 113 💬
41 Epicatechin 1件: Epicatechin---2件: 86, 113 💬
42 Epigallocatechin 1件: Epigallocatechin---5件: 8, 13, 28, 85, 113 💬
43 Eplerenone 1件: Eplerenone1件: Eplerenone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬5件: 57, 75, 113, 210, 215 💬
44 Esomeprazole 3件: Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole5件: Esomeprazole magnesium ,
Esomeprazole sodium ,
Esomeprazole ,
Esomeprazole strontium ,
Esomeprazole magnesium dihydrate 💬 		2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
45 Eteplirsen 1件: ETEPLIRSEN1件: Eteplirsen 💬 1件: DMD 💬 5件: Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
46 Ezutromid 1件: Ezutromid---1件: 113 💬
47 Filgrastim 4件: Filgrastim; G-CSF; Gcsf; GRANULOCYTE COLONY STIMULATING FACTOR1件: Filgrastim 💬 1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬30件: 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
48 Fordadistrogene movaparvovec 1件: Fordadistrogene movaparvovec---1件: 113 💬
49 Gadolinium 1件: Gadolinium---8件: 13, 34, 46, 65, 77, 86, 113, 305 💬
50 Gentamicin 2件: Gentamicin; Gentamicin Sulfate2件: Gentamicin sulfate ,
Gentamicin 💬 		--4件: 13, 36, 113, 299 💬
51 Givinostat 1件: GIVINOSTAT1件: Givinostat 💬 11件: HDAC1,
HDAC10,
HDAC11,
HDAC2,
HDAC3,
HDAC4,
HDAC5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬 		20件: ATP-dependent chromatin remodeling, Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Polycomb repressive complex, TGF-beta signaling pathway, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬2件: 107, 113 💬
52 Gold 1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
53 Golodirsen 1件: GOLODIRSEN1件: Golodirsen 💬 1件: DMD 💬 5件: Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
54 Guanidine 1件: Guanidine1件: Guanidine hydrochloride 💬 --2件: 46, 113 💬
55 GYM329 1件: GYM329---2件: 3, 113 💬
56 Human Umbilical Cord Mesenchymal Stem Cells 2件: Human Umbilical Cord Mesenchymal Stem Cells; Mesenchymal Stromal Cells---5件: 13, 96, 97, 113, 271 💬
57 Ibuprofen 1件: Ibuprofen5件: Ibuprofen ,
Ibuprofen aluminum ,
Ibuprofen lysine ,
Ibuprofen sodium ,
Ibuprofen sodium 💬 		2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
58 Idebenone 1件: Idebenone1件: Idebenone 💬 --9件: 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
59 Ifetroban 2件: Ifetroban; Ifetroban Sodium2件: Ifetroban ,
Ifetroban sodium 💬 		1件: TBXA2R 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬4件: 51, 85, 86, 113 💬
60 Imlifidase 2件: HMed-IdeS; IMLIFIDASE1件: Imlifidase 💬 --4件: 43, 44, 113, 221 💬
61 Isosorbide 1件: Isosorbide1件: Isosorbide 💬 --1件: 113 💬
62 Isosorbide dinitrate 1件: ISOSORBIDE DINITRATE1件: Isosorbide dinitrate 💬 --1件: 113 💬
63 Ketamine 2件: KETAMINE; Ketamine hydrochloride2件: Ketamine hydrochloride ,
Ketamine 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬6件: 6, 13, 70, 113, 156, 215 💬
64 L-arginine 1件: L-arginine---10件: 2, 21, 46, 67, 96, 97, 98, 113, 223, 299 💬
65 L-Glutamine 2件: Glutamine; L-Glutamine1件: Glutamine 💬 --2件: 113, 299 💬
66 Lamotrigine 1件: LAMOTRIGINE1件: Lamotrigine 💬 6件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		5件: Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬7件: 13, 34, 38, 113, 114, 115, 144 💬
67 Lisinopril 1件: Lisinopril2件: Lisinopril ,
Lisinopril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬9件: 19, 46, 49, 57, 66, 67, 113, 222, 223 💬
68 Lonafarnib 1件: Lonafarnib1件: Lonafarnib 💬 2件: FNTA,
FNTB 💬 		1件: Terpenoid backbone biosynthesis 💬2件: 113, 333 💬
69 Losartan 2件: Losartan; LOSARTAN POTASSIUM2件: Losartan potassium ,
Losartan 💬 		1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬20件: 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
70 Losmapimod 1件: Losmapimod1件: Losmapimod 💬 4件: MAPK11,
MAPK12,
MAPK13,
MAPK14 💬 		64件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cadherin signaling, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease, Diabetic cardiomyopathy, Dopaminergic synapse, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬2件: 113, 222 💬
71 Magnesium 2件: MAGNESIO; Magnesium---23件: 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬
72 Magnesium oxide 1件: Magnesium Oxide1件: Magnesium oxide 💬 --4件: 6, 113, 166, 291 💬
73 Mannitol 3件: D-Mannitol; Mannite; MANNITOL1件: Mannitol 💬 --8件: 6, 13, 21, 28, 60, 96, 113, 299 💬
74 Metformin 4件: Metformin; Metformin Hydrochloride; METFORMINA; Metformine2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
75 Methylphenidate 2件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE2件: Methylphenidate hydrochloride ,
Methylphenidate 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206 💬
76 Metoprolol 2件: Metoprolol; Metoprolol Succinate4件: Metoprolol tartrate ,
Metoprolol succinate ,
Metoprolol ,
Metoprolol fumarate 💬 		1件: ADRB1 💬 13件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226 💬
77 Mexiletine 2件: Mexiletine; Mexiletine hydrochloride2件: Mexiletine hydrochloride ,
Mexiletine 💬 		6件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		5件: Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬6件: 1, 2, 10, 113, 114, 115 💬
78 Moxifloxacin 2件: Moxifloxacin; Moxifloxacin hydrochloride3件: Moxifloxacin hydrochloride ,
Moxifloxacin ,
Moxifloxacin hydrochloride monohydrate 💬 		--10件: 2, 6, 46, 49, 85, 86, 113, 226, 240, 299 💬
79 Nebivolol 1件: Nebivolol2件: Nebivolol ,
Nebivolol hydrochloride 💬 		1件: ADRB1 💬 13件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167 💬
80 Nitrate 1件: Nitrate1件: Nitric acid 💬 --6件: 57, 58, 67, 85, 113, 299 💬
81 Omigapil 1件: Omigapil---1件: 113 💬
82 Oxatomide 1件: Oxatomide1件: Oxatomide 💬 1件: ALOX5 💬 6件: Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬1件: 113 💬
83 Pamrevlumab 1件: PAMREVLUMAB1件: Pamrevlumab 💬 1件: CCN2 💬 2件: Apelin signaling pathway, Hippo signaling pathway 💬2件: 85, 113 💬
84 Pemirolast 1件: PEMIROLAST2件: Pemirolast potassium ,
Pemirolast 💬 		--1件: 113 💬
85 Pentoxifylline 1件: Pentoxifylline1件: Pentoxifylline 💬 --13件: 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
86 Perindopril 2件: PERINDOPRIL; PERINDOPRIL ARGININE3件: Perindopril erbumine ,
Perindopril ,
Perindopril arginine 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 57, 58, 113, 167, 222 💬
87 Pitolisant 1件: Pitolisant2件: Pitolisant ,
Pitolisant hydrochloride 💬 		1件: HRH3 💬 2件: Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193 💬
88 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬48件: 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
89 Prednisone 2件: PREDNISONA; PREDNISONE1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
90 Primidone 1件: Primidone1件: Primidone 💬 --2件: 2, 113 💬
91 Ramipril 1件: Ramipril1件: Ramipril 💬 1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬10件: 46, 49, 57, 66, 67, 113, 218, 222, 223, 257 💬
92 Ranolazine 1件: Ranolazine2件: Ranolazine ,
Ranolazine hydrochloride 💬 		--8件: 2, 57, 58, 86, 96, 97, 113, 114 💬
93 Renadirsen 1件: Renadirsen---1件: 113 💬
94 Resveratrol 2件: Resveratrol; Trans-Resveratrol---10件: 2, 6, 8, 18, 46, 57, 89, 97, 113, 299 💬
95 rhIGFBP-3 1件: RhIGFBP-3---2件: 113, 195 💬
96 Ribitol 2件: BBP-418; Ribitol1件: Ribitol 💬 --1件: 113 💬
97 Rimeporide 1件: Rimeporide---1件: 113 💬
98 Risedronic acid 3件: Risedronate; Risedronate Sodium; Risedronic acid3件: Risedronate sodium ,
Risedronic acid ,
Risedronate sodium monohydrate 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬7件: 46, 50, 93, 95, 107, 113, 274 💬
99 Satralizumab 1件: Satralizumab1件: Satralizumab 💬 1件: IL6R 💬 11件: Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬4件: 11, 13, 86, 113 💬
100 Semaglutide 1件: Semaglutide1件: Semaglutide 💬 1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 6, 51, 84, 113, 299 💬
101 Sevasemten 1件: Sevasemten1件: Sevasemten 💬 8件: MYH1,
MYH13,
MYH15,
MYH2,
MYH3,
MYH4,
MYH7B,
MYH8 💬 		2件: Cytoskeleton in muscle cells, Motor proteins 💬1件: 113 💬
102 Sildenafil 3件: Sildenafil; Sildenafil Citrate; SILDENAFILO2件: Sildenafil citrate ,
Sildenafil 💬 		1件: PDE5A 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
103 Sodium nitrate 1件: Sodium Nitrate---2件: 58, 113 💬
104 Spironolactone 1件: Spironolactone1件: Spironolactone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬12件: 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
105 SRD-001 1件: SRD-001---2件: 57, 113 💬
106 SRP-6004 1件: SRP-6004---1件: 113 💬
107 SRP-9005 1件: SRP-9005---1件: 113 💬
108 Suvodirsen 1件: Suvodirsen---1件: 113 💬
109 Tacrolimus 1件: Tacrolimus2件: Tacrolimus ,
Tacrolimus 💬 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
110 Tadalafil 2件: Tadalafil; TADALAFILO1件: Tadalafil 💬 1件: PDE5A 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬8件: 6, 51, 75, 77, 84, 86, 113, 210 💬
111 Tamoxifen 2件: Tamoxifen; TAMOXIFEN CITRATE2件: Tamoxifen citrate ,
Tamoxifen 💬 		2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬6件: 2, 65, 86, 113, 227, 299 💬
112 Testosterone 1件: Testosterone1件: Testosterone 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
113 Testosterone decanoate 1件: Testosterone decanoate1件: Testosterone decanoate 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
114 Testosterone enanthate 1件: Testosterone Enanthate1件: Testosterone enanthate 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
115 Testosterone isocaproate 1件: Testosterone isocaproate---1件: 113 💬
116 Testosterone phenylpropionate 1件: Testosterone phenylpropionate1件: Testosterone phenylpropionate 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
117 Testosterone propionate 1件: Testosterone propionate1件: Testosterone propionate 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
118 Tetracosactide 3件: Cosyntropin; Tetracosactide; Tetracosactide Acetate2件: Cosyntropin ,
Tetracosactide acetate 💬 		1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 83, 113, 145, 222 💬
119 Tideglusib 1件: Tideglusib---3件: 2, 5, 113 💬
120 Tranilast 1件: Tranilast1件: Tranilast 💬 --4件: 46, 84, 106, 113 💬
121 Trehalose 2件: Cabaletta; Trehalose---4件: 2, 6, 18, 113 💬
122 Vamorolone 1件: VAMOROLONE1件: Vamorolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬2件: 97, 113 💬
123 Vesleteplirsen 1件: Vesleteplirsen---1件: 113 💬
124 Viltolarsen 1件: VILTOLARSEN1件: Viltolarsen 💬 1件: DMD 💬 5件: Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
125 WVE-N531 1件: WVE-N531---1件: 113 💬
126 Yeast 1件: Yeast1件: Dried yeast 💬 --2件: 97, 113 💬